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An　SCF－MS－Xα　Study　of　the　Electronic　Structures　of　Binuclear　and　Trinuclear　Gold（Ⅰ）　Compounds

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Chemical Research in Chinese Universities 1996年第4期12卷 378-389页

作者： GUO chun-xiao(Department of Chemistry,Jilin University,changchun,130023)chan Chi-keung and CHE Chi-ming(Department of Chemistry,University of Hongkong,Hongkong) JILIN UNIV DEPT CHEMCHANGCHUN 130023PEOPLES R CHINA UNIV HONG KONG DEPT CHEMHONG KONGHONG KONG

The SCF-Xα-SW molecular orbital calculations were carried out on the modelcompounds of binuclear and trinuclear gold(Ⅰ)using starting potential of Au atom and the Watson *** energy level order of the frontier orbital of a binuclear gold model compound is in agreement with the experimental *** calculated ionization potential of the binuclear model compound is consistent well with the photoelectron spectrum of Au (Me)(PMe_3).The metal-metal interactions are *** calculated electronic absorption spectra of binuclear and trinuclear gold(Ⅰ)are basically in agreement with experimental results.

关键词： s:Electronic structure,SCF-Xα-SW Gold(Ⅰ)

Bevacizumab for neovascular age-related macular degeneration in Chinese patients in a clinical setting

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International Journal of Ophthalmology(English edition) 2016年第3期9卷 424-430页

作者： Danny Siu-chun Ng Alvin Kwan-Ho Kwok Justin Man-Kit Tong Clement Wai-Nang chan Walton Wai-Tat Li Department of Ophthalmology & Visual Sciences the Chinese University of Hong Kong Department of Ophthalmology Hong Kong Sanatorium and Hospital Department of Ophthalmology United Christian Hospital

AIM：To determine the outcome of non-investigational treatment with intravitreal bevacizumab（IVB） in neovascular age-related macular degeneration（AMD）patients.· METHODS：Retrospective chart review of 81 eyes with neovascular AMD followed-up for at least 12 mo and received 3-monthly loading IVB ***-treat was based upon the individual clinician＇s *** visual acuity（BCVA） and optical coherence tomography measurements of central foveal thickness outcomes were evaluated at 12,24 mo.· RESULTS：Eighty-one eyes（of 75 patients） completed12 mo of follow-up and 44 eyes（of 41 patients） completed24 mo of *** mean baseline logMAR BCVA significantly improved from 0.94±0.69 to 0.85±0.68 at12mo（P〈0.001） and from 0.91±0.65 to 0.85±0.60（P=0.004）at 24 *** proportion of eyes that lost 〈15 logMAR letters at 12 mo was 90.1%and at 24 mo was 81.8%.IVB was effective in improving visual acuity in both treatment naive and previous photodynamic therapy（PDT）-treated *** naive patients required significantly fewer injections than patients with prior *** regression analysis identified that poorer baseline visual acuity was associated with greater improvement in visual acuity（P=0.015）.· CONCLUSION：Fewer injections in clinical practice may result in suboptimal visual outcomes compared with clinical trials of IVB in neovascular AMD *** baseline visual acuity and prior PDT treatment may also improve vision after *** safety and durability of effect was maintained at 24 mo.

关键词： bcvacizumab age-related maculardegeneration Chinese

Turbulent flows over real heterogeneous urban surfaces:Wind tunnel experiments and Reynolds-averaged Navier-Stokes simulations

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Building Simulation 2021年第5期14卷 1345-1358页

作者： Wai-Chi Cheng chun-Ho Liu Yat-Kiu Ho Ziwei Mo Zhangquan Wu Wenye Li Lilian Y.L.chan W.K.Kwan Hing Tuen Yau School of Atmospheric Sciences and Guangdong Province Key Laboratory for Climate Change and Natural Disaster StudiesSun Yat-sen UniversityZhuhaiChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina Department of Mechanical Engineering The University of Hong KongHong KongChina Information Technology Services The University of Hong KongHong KongChina

Wind tunnel experiment and steady-state Reynolds-averaged Navier-Stokes(RANS)approaches are used to examine the urban boundary layer(UBL)development above Kowloon Peninsula,Hong Kong Special Administrative Region(HKSAR).The detailed urban morphology is resolved by computational fluid dynamics(CFD)and is fabricated by 3D-printing(reduced scale)for wind tunnel *** from the majority existing results based on idealized,homogeneous urban geometries,it was found that the wind and turbulence in the UBL over downtown Kowloon are characterized by the wake behind several high-rise *** particular,local maxima of turbulence kinetic energy(TKE)and shear stress are found at the roof level of those high-rise *** the downstream region where the flows are already adjusted to the urban surfaces,the urban roughness sublayer(URSL)can be further divided into two layers based on the structures of the mixing length/m,effective drag Dx and dispersive *** the lower URSL(z<100 m),lm is rather uniform,and the Reynolds stress and dispersive stress are *** the upper URSL(100 m z s 300 m),on the contrary,lm is peaked at the mid-height and the magnitude of dispersive stress is smaller than that of the Reynolds stress(<30%).The effective drag Dx is negligible in the upper URSL.

关键词： computational fluid dynamics(CFD) real urban morphology urban boundary layer(UBL) urban canopy model(UCM) wind tunnel experiments

One-year real-world outcomes of ranibizumab 0.5 mg treatment in Taiwan Residents patients with polypoidal choroidal vasculopathy： a subgroup analysis of the REAL study

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International Journal of Ophthalmology(English edition) 2018年第11期11卷 1802-1808页

作者： San-Ni Chen Cheng-Kuo Cheng Ling Yeung Jiann-Torng Chen Wei-chun chan Jorn-Hon Liu Shwu-Jiuan Sheu Wen-Chuan Wu Chi-chun Lai changhua Christian Hospital Changhua Taiwan 50094China College of Medicine Chung Shan Medical UniversityTaichung City Taiwan 40246 China Shin Kong Wu Ho-Su Memorial Hospital Shilin DistrictTaipei City Taiwan 11101 China chang Gung Memorial Hospital-Keelung Anle DistrictKeelung City Taiwan 204 China Tri-Service General Hospital Chenggong Road Taipei CityTaiwan 11490 China Mackay Memorial Hospital Zhongshan District Taipei CityTaiwan 813 China Cheng Hsin General Hospital Beitou District Taipei CityTaiwan 112 China Kaohsiung Veterans General Hospital Zuoying DistrictKaohsiung City Taiwan 81362 China Kaohsiung Medical University chung-Ho Memorial Hospital Sanmin District Kaohsiung City Taiwan 807 China chang Gung Memorial Hospital-Linkou Guishan DistrictTaoyuan City Taiwan 333 China

AIM： To assess the effectiveness and safety of ranibizumab 0.5 mg in Taiwan Residents patients with polypoidal choroidal vasculopathy（PCV） by performing a retrospective exploratory subgroup analysis of the REAL ***： REAL was a 12-month, observational, prospective, non-interventional phase IV post-marketing surveillance study conducted at 9 centers in Taiwan. The study collected data as part of the routine patient visits from the medical records of patients with neovascular agerelated macular degeneration treated with ranibizumab 0.5 mg according to local standard medical practice and local label and/or reimbursement guidelines. The presence of PCV at baseline was determined using indocy received prior tanine green angiography. RESULTS： At baseline, PCV was diagnosed in 64 of the 303 enrolled patients（21.1%）. Of these, 41 patients（64.1%） hadreatment; 15（23.4%） patients had received ranibizumab. The intent-to-treat population included 58 patients; 47（80%） who received ranibizumab and 11（20%） who received ranibizumab plus photodynamic therapy（PDT; 9 patients received once, 2 patients received twice）. Bevacizumab was used as a concomitant medication in a similar percentage of patients who received ranibizumab（43%, n=20） or ranibizumab plus PDT（45%, n=5）. In patients who received ranibizumab, visual acuity（VA） at baseline was 50.1±12.9 Early Treatment Diabetic Retinopathy Study letters, and the gain at month 12 was 1.1±17.8 letters. In patients who received ranibizumab plus PDT, VA at baseline was 51.4±15.9 letters, and there was a marked gain in VA at month 12（14.0±9.2 letters, P=0.0009）. In the intent-totreat population, the reduction in central retinal subfield thickness from baseline at month 12 was 69.6±122.6 μm（baseline： 310.8±109.8 μm, P=0.0004）. The safety results were consistent with the well-characterized safety profile of ***： In real-world settings, ranibizumab 0.5 mg treatment for 12 mo results in maintenance of VA and reduction

关键词： observational study polypoidal choroidal vasculopathy ranibizumab Taiwan visual acuity

Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men

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Asian Journal of Andrology 2019年第5期21卷 468-472页

作者： Jeremy Yuen-chun Teoh Chi-Kwok chan Maggie Haitian Wang Chi-Ho Leung Eddie Shu-Yin chan Peter Ka-Fung Chiu Chi-Hang Yee Hon-Ming Wong Simon See-Ming Hou Chi-Fai Ng S.H.Ho Urology Centre Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Division of Biostatistics JC School of Public Health and Primary CareThe Chinese University of Hong KongHong KongChina Division of Urology Department of SurgeryNorth District HospitalHong KongChina Division of Urology Department of SurgeryAlice Ho Miu Ling Nethersole HospitalHong KongChina

It is largely unknown whether lower urinary tract symptoms(LUTS)or acute retention of urine(AROU)is linked to shorter life expectancy in *** conducted a multicenter,retrospective database analysis of patients undergoing transurethral resection of prostate(TURP)to study their *** Cox regression analysis and Kaplan-Meier analysis with stratification to age and indication of TURP were *** further performed an age-and sex-matched survival analysis with the general population using data from the Census and Statistics Department of the Hong Kong Special Administrative Region(Hong Kong,China).From January 2002 to December 2012,3496 patients undergoing TURP were included in our study,with 1764 patients in the LUTS group and 1732 patients in the AROU *** age,ischemic heart disease,cerebrovascular accident,and AROU were risk factors of *** aged80 *** to the general population,younger patients in the LUTS group appeared to have better survival(80 years,survival was similar with the general population in both the LUTS and AROU *** conclusion,AROU at young age was associated with mortality,while early detection and management of LUTS may improve survival.

关键词： acute retention of urine lower urinary tract symptoms mortality transurethral resection of prostate

Predicting tumor response after preoperative chemoradiation using clinical parameters in rectal cancer

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World Journal of Gastroenterology 2011年第48期17卷 5310-5316页

作者： chan Ho Park Hee Cheol Kim Yong Beom Cho Seong Hyeon Yun Woo Yong Lee Young Suk Park Doo Ho Choi Ho-Kyung chun Departmentof Surgery Samsung Medical Center Sungkyunkwan Univer-sity School of Medicine Irwon-dong 50 Gangnam-gu Seoul135-710 South Korea Division of Hematology-Oncology Depart-ment of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Irwon-dong 50 Gangnam-guSeoul 135-710 South Korea Department of Radiation Oncology SamsungMedical Center Sungkyunkwan University School of MedicineIrwon-dong 50 Gangnam-gu Seoul 135-710 South Korea

AIM: To evaluate the clinical parameters and identify a better method of predicting pathological complete response (pCR). METHODS: We enrolled 249 patients from a database of 544 consecutive rectal cancer patients who underwent surgical resection after preoperative chemoradiation therapy (PCRT). A retrospective review of morphological characteristics was then performed to collect data regarding rectal examination findings. A scoring model to predict pCR was then created. To validate the ability of the scoring model to predict complete ***: Seventy patients (12.9%) achieved a pCR. A multivariate analysis found that pre-CRT movability (P = 0.024), post-CRT size (P = 0.018), post-CRT morphology (P = 0.023), and gross change (P = 0.009) were independent predictors of pCR. The accuracy of the scoring model was 76.8% for predicting pCR with the threshold set at 4.5. In the validation set, the accuracy was 86.7%. CONCLUSION: Gross changes and morphological findings are important predictors of pathological response. Accordingly, PCRT response is best predicted by a combination of clinical, laboratory and metabolic information.

关键词： Rectal cancer Preoperative chemoradiotherapy Downstaging Tumor regression Validation

高血压脑病、急性肾损伤伴双肾肿大:儿童非霍奇金淋巴瘤1例

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临床肾脏病杂志 2024年第5期24卷 437-440页

作者：孙晓颖王雨雪黄玉婵王鑫磊李春珍河北省儿童医院肾脏免疫科石家庄050000

非霍奇金淋巴瘤(non-Hodgkin lymphoma,NHL)伴高血压脑病病例国内外少有报道,我们报告1例以高血压脑病起病的儿童,其表现为一过性双眼黑蒙伴双眼右斜、口唇发绀。患儿为6岁女孩,既往体健,起病急,在常规体格检查中发现其血压升高。该患... 详细信息

非霍奇金淋巴瘤(non-Hodgkin lymphoma,NHL)伴高血压脑病病例国内外少有报道,我们报告1例以高血压脑病起病的儿童,其表现为一过性双眼黑蒙伴双眼右斜、口唇发绀。患儿为6岁女孩,既往体健,起病急,在常规体格检查中发现其血压升高。该患儿以高血压脑病为首发症状就诊,这是一种罕见的淋巴瘤的非典型表现。肾脏淋巴瘤常见表现包括急性肾功能衰竭、腰痛、血尿、体重减轻和腹部肿块。入院后出现急性肾损伤,双肾呈弥漫性肿大,经肾穿刺活检取肾脏病理组织,确诊为B淋巴母细胞性淋巴瘤。根据病情入院后给予抗感染、降压、利尿及化疗等综合治疗,随访9个月,目前处于疾病缓解期。肾脏淋巴瘤的表现多种多样,尤其是无肾外受累的原发性肾淋巴瘤。易误诊、漏诊,及时、早期进行肾脏病理穿刺活检对于诊断有重要意义。

关键词：非霍奇金淋巴瘤高血压脑病急性肾损伤肾脏淋巴瘤儿童

SNOS：一种传感器网络操作系统的设计与实现

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电子学报 2005年第B12期33卷 2485-2492页

作者：孙岩陈振冲中国科学院软件研究所北京100080 中国科学院研究生院北京100039 香港理工大学电子计算学系香港

传感器网络是一种新型的网络信息系统，其独特的特点包括：它是一个自组织网络，其运行和应用服务以传感器数据及数据聚合为中心，中间结点与信息服务紧密融合等．这些特征为操作系统研究领域提出了新的课题．本文提出了一种传感器网络... 详细信息

传感器网络是一种新型的网络信息系统，其独特的特点包括：它是一个自组织网络，其运行和应用服务以传感器数据及数据聚合为中心，中间结点与信息服务紧密融合等．这些特征为操作系统研究领域提出了新的课题．本文提出了一种传感器网络操作系统一SNOS（Sensor Network Operating System），该操作系统以满足传感器网络的特点和需求为目标设计完成．本文论述了SNOS系统的结构和设计，系统资源机制和运行管理机制，介绍了SNOS系统任务实现的模拟试验和系统原型在煤矿井下初步应用的情况，为传感器网络操作系统的设计研究提供了思路和参考．

关键词：无线传感器网络操作系统数据聚合系统资源模拟试验原型

Development of Dual Phosphorescent Materials Based on Multiple Stimuli-Responsive Ir(Ⅲ)Acyclic Carbene Complexes

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CCS Chemistry 2022年第7期4卷 2354-2368页

作者： Jingqi Han Yuen-Kiu chun Shing-Lun chan Shun-Cheung Cheng Shek-Man Yiu Chi-Chiu Ko Department of Chemistry City University of Hong KongKowloonHong Kong 999077

A new series of Ir(Ⅲ)carbene complexes with luminescent mechanochromism derived from trans-cis isomerization has been *** the introduction of π-conjugating groups into the acyclic carbene ligand,the mechanochromic trans-and cisconfigurations can be readily interconverted,leading to dual emissive properties in the solid ***,the solid-or film-forming solvent system can control the dual emission and mechanoresponsive properties in the solid *** potential uses of a single emissive complex to develop multicolor emissive and multiple stimuli-responsive films have been studied.

关键词： luminescent mechanochromism iridium(Ⅲ)cyclometallates luminescent vapochromism dual emission