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临床超声医学杂志 2019年第9期21卷 681-684页

作者：黄丽珍王荣荣罗雅峰苏洁马阿利许磊安军明康亚宁陕西中医药大学附属西安市中医医院超声科西安市710016 陕西中医药大学附属西安市中医医院针灸推拿康复科西安市710016

目的探讨实时剪切波弹性成像(SWE)评价颈肩部肌筋膜疼痛综合征(MPS)患者经阿是穴针刺治疗的疗效。方法应用SWE技术定量测量30例颈肩部MPS患者经阿是穴针刺治疗前后斜方肌疼痛触发点的弹性模量值及弹性评分,应用视觉模拟评分(VAS)法评估... 详细信息

目的探讨实时剪切波弹性成像(SWE)评价颈肩部肌筋膜疼痛综合征(MPS)患者经阿是穴针刺治疗的疗效。方法应用SWE技术定量测量30例颈肩部MPS患者经阿是穴针刺治疗前后斜方肌疼痛触发点的弹性模量值及弹性评分,应用视觉模拟评分(VAS)法评估其主观疼痛强度,分析治疗前VAS评分与杨氏模量值及弹性评分的相关性,以及针刺治疗后VAS评分变化值(ΔVAS)与杨氏模量变化值(Δ杨氏模量值)及弹性评分变化值(Δ弹性评分)的相关性。结果与阿是穴针刺治疗前比较,颈肩部MPS患者针刺治疗后斜方肌疼痛触发点弹性评分及杨氏模量值均明显降低(t=6.34、33.36,均P<0.001),VAS评分减低(t=10.02,P<0.001)。阿是穴针刺治疗前,颈肩部MPS患者VAS评分与杨氏模量值及弹性评分均呈正相关(r=0.572、0.474,均P<0.05);阿是穴针刺治疗后,颈肩部MPS患者ΔVAS与Δ杨氏模量值及Δ弹性评分均呈正相关(r=0.611、0.561,均P<0.05)。结论SWE能客观有效地评估颈肩部MPS患者阿是穴针刺疗效,具有较好的临床应用价值。

关键词：剪切波弹性成像肌筋膜疼痛综合征针灸,阿是穴

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补肾活血方对复发性流产孕鼠Th17/Treg平衡及妊娠结局的影响

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现代中西医结合杂志 2022年第16期31卷 2230-2235页

作者：陈颖庆邓阿黎陈林娜周忠明王燕萍金晶向英吴双徐静余念卢雯婷李婷詹妮湖北中医药大学湖北武汉430065 湖北中医药大学附属湖北省中医院湖北武汉430060

目的观察补肾活血方对复发性流产(RSA)孕鼠辅助性T细胞17(Th17)/调节性T细胞(Treg)平衡及相关细胞因子水平和妊娠结局的影响。方法将雌性CBA/j小鼠与雄性DBA/2小鼠按照2∶1比例交配建立RSA模型,成功后将RSA小鼠随机分为模型组、地屈孕... 详细信息

目的观察补肾活血方对复发性流产(RSA)孕鼠辅助性T细胞17(Th17)/调节性T细胞(Treg)平衡及相关细胞因子水平和妊娠结局的影响。方法将雌性CBA/j小鼠与雄性DBA/2小鼠按照2∶1比例交配建立RSA模型,成功后将RSA小鼠随机分为模型组、地屈孕酮组和补肾活血方低、中、高剂量组,每组10只;另将雌性CBA/j小鼠与雄性BALB/C小鼠按照2∶1交配,取正常妊娠的10只雌性小鼠作为正常妊娠组。妊娠第1天,正常妊娠组和模型组孕鼠给予生理盐水灌胃,地屈孕酮组孕鼠给予6.18 mg/kg地屈孕酮灌胃,补肾活血方低、中、高剂量组孕鼠分别给予7.83 g/kg、15.67 g/kg、31.34 g/kg补肾活血方灌胃,均每天1次,连续14 d。疗程结束,取各组孕鼠外周血,检测血清中白细胞介素-17(IL-17)、转化生长因子-β(TGF-β)水平,计算IL-17/TGF-β比值;处死孕鼠,计算胚胎吸收率;流式细胞术检测脾脏淋巴细胞中Th17细胞比例、Treg细胞比例,计算Th17/Treg比值。结果与模型组比较,地屈孕酮组及补肾活血方各组孕鼠血清IL-17水平及IL-17/TGF-β比值、胚胎吸收率、脾脏淋巴细胞中Th17细胞比例和Th17/Treg比值均明显降低(P均0.05)。结论补肾活血方可能通过调节Th17/Treg平衡及相关细胞因子水平,使母胎免疫耐受,改善小鼠妊娠结局。

关键词：复发性流产小鼠补肾活血辅助性T细胞17 调节性T细胞妊娠结局

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Feasibility and physics potential of detecting ^(8)B solar neutrinos at jUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop joão Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao jun Cao Rossella Caruso Cédric Cerna jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The jiangmen Underground Neutrino Observatory(jUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of jUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of jUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),jUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,jUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino jUNO

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