检索结果-南通市图书馆

Effects of aqueous extract from red Liriope platyphylla on phthalic-anhydride-induced atopic dermatitis in Interleukin-4/Luciferase/Consensus non-coding sequence-1 transgenic mice evaluated in terms of luciferase signal and general phenotype biomarkers

引用

Journal of Traditional Chinese Medicine 2017年第4期37卷 475-485页

作者： moon Hwa Kwak Ji eun Kim Jun Go Hong Joo Son Hee Seob Lee Jin Tae Hong Dae Youn Hwang College of Natural Resources and Life Science/Life and Industry Convergence Research Institute Pusan National UniversityMiryang 627-706South of Korea College of Human Ecology Pusan National UniversityBusan 609-735south of Korea College of Pharmacy and Medical Research Center Chungbuk National UniversityChungju 361-763south of Korea College of Pharmacology Chungbuk National UniversityChungju 361-763south of Korea

OBJECTIVE: To quantitatively evaluate the therapeutic effects of Red Liriope platyphylla(RLP) on atopic dermatitis(AD), alterations in the luciferase(Luc) signal and general phenotype biomarkers were compared in phthalic anhydride(PA) treated Interleukin-4(IL-4)/Luc/Consensus non-coding sequence-1(CNS-1) transgenic(Tg) mice following treatment with aqueous extract of RLP(AEt RLP) for4 ***: Alterations in AD phenotypes were measured in IL-4/Luc/CNS-1 Tg mice following treatment with AEt RLP using inflammation parameter analysis, bioluminescence imaging analysis, histological analysis, reverse transcription-polymerase chain reaction, enzyme linked immunosorbent assay and Western blot ***: RLP contained high concentrations of total phenolic compounds, total flavonoid compounds and 5-HNE related to AD therapy. The Luc signal was only detected in the abdominal region and the submandibular lymph node(SL), mesenteric lymph node(ML), thymus and pancreas of the PA treated group. This signal was significantly decreased by 28%-73% throughout the body and in the four organs in PA + AEt RLP treated group. Furthermore, the lymph node weight, immunoglobulin E concentration and dermal thickness were decreased by 37%-67% in the PA + AEt RLP treated ***: Our findings suggest that the therapeutic effect of AEt RLP on PA induced AD could be successfully quantified by comparison of Luc signals and AD phenotype markers in IL-4/Luc/CNS-1Tg mice, and that the Luc signal was as sensitive as the general AD phenotypes, enabling detection of effects without euthanasia.

关键词： Dermatitis, Atopic Liriope plant Interleukin-4 Luciferases Mice, transgenic Phthalic anhydrides Immunoglobulin E

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Congenital absence of the splenic artery and splenic vein accompanied with a duodenal ulcer and deformity

引用

World Journal of Gastroenterology 2009年第11期15卷 1401-1403页

作者： eun Kyung Shin Won moon Seun Ja Park Moo In Park Kyu Jong Kim Jee Suk Lee Jin Hwan Kwon Department of Gastroenterology Kosin University College of MedicineBusanSouth Korea Department of Radiology Kosin University College of MedicineBusanSouth Korea

Congenital absence of the splenic artery is a very rare *** the best of our knowledge, congenital absence of the splenic artery accompanied with absence of the splenic vein has not been *** report a case of the absence of the splenic artery and vein in a 61-year-old woman who presented with postprandial epigastric discomfort. Upper gastrointestinal endoscopy showed a dilated, pulsatile vessel in the fundus and duodenal stenosis. An abdominal computed tomography(CT)scan revealed absence of the splenic vein with a tortuously engorged gastroepiploic ***-dimensional CT demonstrated the tortuously dilated left gastric artery and the left gastroepiploic artery with non-visualization of the splenic *** administration of a proton pump inhibitor,abdominal symptoms resolved without any recurrence of symptoms during 6 mo of follow-up.

关键词： Congenital Anomaly Splenic artery Splenic vein Duodenum Ulcer Deformity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles

引用

World Journal of Stem Cells 2022年第7期14卷 527-538页

作者： Ramya Lakshmi Rajendran Prakash Gangadaran Mi Hee Kwack Ji Min Oh chae moon Hong Young KwanSung Jaetae Lee Byeong-Cheol Ahn Department of Nuclear Medicine School of MedicineKyungpook National UniversityDaegu 41944South Korea BK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents Department of Biomedical SciencesSchool of MedicineKyungpook National UniversityDaegu 41944South Korea Department of Immunology School of MedicineKyungpook National UniversityDaegu 41944South Korea Department of Nuclear Medicine Kyungpook National University HospitalDaegu 41944South Korea

BACKGROUND Dermal papillae(DP)and outer root sheath(ORS)cells play important roles in hair growth and regeneration by regulating the activity of hair follicle(HF)*** To investigate the effects of human mesenchymal stem cell-derived extracellular vesicles(hMSC-EVs)on DP and ORS cells as well as *** are known to regulate various cellular ***,the effects of hMSC-EVs on hair growth,particularly on human-derived HF cells(DP and ORS cells),and the possible mechanisms underlying these effects are *** hMSC-EVs were isolated and characterized using transmission electron microscopy,nanoparticle tracking analysis,western blotting,and flow *** activation of DP and ORS cells was analyzed using cellular proliferation,migration,western blotting,and real-time polymerase chain *** growth was evaluated ex vivo using human *** Wnt3a is present in a class of hMSC-EVs and associated with the EV ***-EVs promote the proliferation of DP and ORS ***,they translocateβ-catenin into the nucleus of DP cells by increasing the expression ofβ-catenin target transcription factors(Axin2,EP2 and LEF1)in DP *** with hMSC-EVs also promoted the migration of ORS cells and enhanced the expression of keratin(K)differentiation markers(K6,K16,K17,and K75)in ORS ***,treatment with hMSC-EVs increases hair shaft elongation in cultured human *** These findings suggest that hMSC-EVs are potential candidates for further preclinical and clinical studies on hair loss treatment.

关键词： Mesenchymal stem cells Extracellular vesicles Hair growth Dermal papillae Outer root sheath cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Superior mesenteric vein thrombosis induced by influenza infection:A case report

引用

World Journal of Clinical Cases 2020年第18期8卷 4193-4199页

作者： Gyu Man Oh Kyoungwon Jung Jae Hyun Kim Sung eun Kim Won moon Moo In Park Seun Ja Park Department of Internal Medicine Kosin University College of MedicineBusan 49267South Korea

BACKGROUND Among the various types and causes of mesenteric ischemia,superior mesenteric vein(SMV)thrombosis is a rare and ambiguous *** a patient presents with SMV thrombosis,past medical history should be reviewed,and the patient should be screened for underlying *** thrombosis may also occur due to systemic *** this report,we describe a case of SMV thrombosis complicated by influenza B *** SUMMARY A 64-year-old male visited the hospital with general weakness,muscle aches,fever,and abdominal *** patient underwent computed tomography(CT)and was diagnosed with SMV *** the patient’s muscle pain and fever could not be explained by the SMV thrombosis,the clinician performed a test for influenza,which produced a positive result for influenza *** patient had a thrombus in the SMV only,with no invasion of the portal or splenic veins,and was clinically *** treatment was prescribed without surgery or other *** follow-up CT scan showed improvement,and the patient was subsequently discharged with continued oral anticoagulant *** This case provides evidence that influenza may be a possible risk factor for SMV *** unexplained abdominal pain is accompanied by an influenza infection,examination of an abdominal CT scan may be necessary to screen for possible SMV thrombosis.

关键词： Influenza B virus Mesenteric ischemia Venous thrombosis Mesenteric vascular occlusion Influenza Human Case reports

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coherent interface driven super-plastic elongation of brittle intermetallic nano-fibers at room temperature

引用

Journal of Materials Science & Technology 2022年第20期115卷 97-102页

作者： eun-Ae Choi Seung Zeon Han Hyung Giun Kim Jee Hyuk Ahn Sung Hwan Lim Sangshik Kim Nong-moon Hwang Kwangho Kim Jehyun Lee Department of Special Alloy Korea Institute of Materials ScienceChangwon 642-831Korea Gangwon Regional Division Korea Institute of Industrial TechnologyGangneung 210-340Korea Department of Advanced Materials Science&Engineering Kangwon National UniversityChuncheon 200-701Korea Department of Materials Science and Engineering ReCAPTGyeongsang National UniversityChinju 660-701Korea Department of Materials Science and Engineering Seoul National UniversitySeoul 151-744Korea Department of Materials Science and Engineering Pusan National UniversityBusan 46241Korea Department of Materials Science and Engineering Changwon National UniversityChangwon 641-773Korea

The intermetallic compound such as Ni_(2)Si has a brittle ***,monolithic intermetallic compounds have not yet been prepared by mechanical *** mechanical drawing of bulk CuNi_(2)Si alloy at room temperature,we observed more than 400%plastic elongation of hard and brittle Ni_(2)Si intermetallic *** calculation based on the density functional theory reveals that the fully coherent interface induces strain on the intermetallic compound surrounded by the matrix,and lowers the intrinsic stacking fault energy below the level required to break an interatomic *** new interface between the Ni_(2)Si intermetallic and Cu matrix formed by the plastic deformation is as stable as the original coherent interface formed by precipitation,and the activation energy of the newly formed interface to slip is similar to that of the Cu *** of these make plastic deformation of brittle Ni_(2)Si intermetallic possible by slip without failure.

关键词： Ni_(2)Si Intermetallic compound Plastic deformation Precipitation Brittle fiber Interface Density functional theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mineralogical characteristics of bentonites occurring in Ningcheng and Jianping area,China

引用

Science China Earth Sciences 2010年第4期53卷 541-549页

作者： GU JaRang moon YongHee moon HiSoo Department of Earth System Sciences Yonsei University Institute of Earth Atmosphere Astronomy BK21 Yonsei University

This study is focused on the basic mineralogical and chemical characteristics of some selected samples from Jianping(JP) and Ningcheng(NC) area,*** were studied using X-ray diffraction(XRD),expandability,Greene-Kelly test,specific surface area,cation exchange capacity(CEC),differential thermal analysis(DTA),and chemical *** bulk samples consist of mainly montmorillonites along with appreciable amounts of cristobalite and with small amounts of quartz,feldspar and *** basal spacings of montmorillonites in all these examined samples show at about 1.5 nm,indicating that pre-dominant cations were *** crystallite thickness of the present sample lies from 0.449 to 0.710 nm(4.58-7.24 layers).As Greene-Kelly test,samples from Ningcheng area confirmed appreciable amount of beidellite component but samples from Jianping area did not contain anything about *** area of samples varies from 671 to 766 m2 g-1 depending on the amounts of *** CEC ranges from 70.30 to 82.75 meq 100g-1 in <2 μm size *** DTA curves are considered abnormal *** from Ningcheng area show relatively higher amount of SiO2 than those from Jianping area,possibly due to difference of parent rock *** element(Y,Nb,Ce and Zr) data are plotted on acidic to intermediate *** is apparent that no large chemical transfer would have been necessary during alteration.

关键词： montmorillonite beidellite expandability Greene-Kelly test trace element

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Faraday rotations,ellipticity,and circular dichroism in magneto-optical spectrum of moire superlattices

引用

Chinese Physics B 2021年第7期30卷 18-32页

作者： J A Crosse Pilkyung moon Arts and Sciences New York University ShanghaiShanghai 200122China NYU-ECNU Institute of Physics at NYU Shanghai Shanghai 200062China Department of Physics New York UniversityNew York 10003USA

We study the magneto-optical conductivity of a number of van der Waals heterostructures,namely,twisted bilayer graphene,AB–AB and AB–BA stacked twisted double bilayer graphene and monolayer graphene and AB-stacked bilayer graphene on hexagonal boron *** the magnetic field increases,the absorption spectrum exhibits a self-similar recursive pattern reflecting the fractal nature of the energy *** twisted bilayer graphene displays only weak circular dichroism,the other four structures display strong circular dichroism with monolayer graphene and AB-stacked bilayer graphene on hexagonal boron nitride being particularly pronounced owing to strong inversion symmetry breaking properties of the hexagonal boron nitride *** the left and right circularly polarized light interact with these structures differently,plane-polarized incident light undergoes a Faraday rotation and gains an ellipticity when *** size of the respective angles is on the order of a degree.

关键词： 2D-materials van der Waals heterostructures magneto-optical conductivity graphene

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The role of vasoepididymostomy for treatment of obstructive azoospermia in the era of in vitro fertilization:a systematic review and meta-analysis

引用

Asian Journal of Andrology 2019年第1期21卷 67-73页

作者： Young eun Yoon Hyung Ho Lee Sung Yul Park Hong Sang moon Dong Suk Kim Seung-Hun Song Dae Keun Kim Department of Urology Hanyang University College of MedicineSeou104763Korea Department of Urology National Health Insurance Corporation Ilsan Hospital Gyeonggi-do 10444Korea Department of Urology Fertility Center of CHA Gangnam Medical CenterCHA UniversitySeou106135Korea Department of Urology CHA Seoul Station Fertility CenterCHA UniversitySeou104637Korea Department of Urology School of MedicineGraduate SchoolHanyang UniversitySeou104763Korea

This study comprises a systematic review and meta-analysis of micmsurgical vasoepididymostomy outcomes in epididymal obstructive azoospermia.A comprehensive literature search was performed using Medline,Embase,and the Cochrane library that included all studies related to microsurgical *** included “vasoepididymostomy,”“epididymovasostomy,”“epididymal obstruction,”and “epididymis obstruction.”Event rate and risk ratio (RR)were *** rate and pregnancy rate were *** analysis comprised 1422 articles,including 42 observational studies with 2298 enrolled patients performed from November 1978 to January *** overall mean patency rate was 64.1%(95%confidence interval [CI]:58.5%-69.3%;F=83.0%),and the overall mean pregnancy rate was 31.1%(95%CI:26.9%-35.7%;I^2=73.0%).We performed a meta-analysis comparing the patency rate of bilateral microsurgical vasoepididymostomy and unilateral microsurgical vasoepididymostomy and found an RR of 1.38%(95%CI: 1.21%-1.57%;P <0.00001).A comparison of the site of microsurgical vasoepididymostomy showed that caudal or corpus area was favorable for patency rate (RR =1.17%;95%CI: 1.01%-1.35%;P =0.04).Patients with motile sperm in epididymal fluid exhibited an RR of 1.53%(95%CI:1.11%-2.13%;P =0.01)with respect to patency rate. Microsurgical vasoepididymostomy is an effective treatment for epididymal obstructive azoospermia that can improve male fertility. We find that performing microsurgical vasoepididymostomy bilaterally,anastomosing a larger caudal area,and containing motile sperm in epididymis fluid can potentially achieve a superior patency rate.

关键词： azoospermia meta-analysis vasoepididymostomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Favorable surgical treatment outcomes for chronic constipation with features of colonic pseudo-obstruction

引用

World Journal of Gastroenterology 2012年第32期18卷 4441-4446页

作者： Eon Chul Han Heung-Kwon Oh Heon-Kyun Ha eun Kyung Choe Sang Hui moon Seung-Bum Ryoo Kyu Joo Park Department of Surgery Seoul National University College of MedicineSeoul 110-744South Korea Seoul National University Hospital Gangnam Center Seoul 110-744South Korea

AIM:To determine long-term outcomes of surgical treatments for patients with constipation and features of colonic ***:Consecutive 42 patients who underwent surgery for chronic constipation within the last 13 years were prospectively *** identified a subgroup with colonic pseudo-obstruction(CPO) features,with dilatation of the colon proximal to the narrowed transitional zone,in contrast to typical slowtransit constipation(STC),without any dilated colonic *** outcomes of surgical treatments for chronic constipation with features of CPO were analyzed and compared with outcomes for ***:Of the 42 patients who underwent surgery for constipation,33 patients had CPO with dilatation of the colon proximal to the narrowed transitional *** were 16 males and 17 females with a mean age of 51.2 ± 16.1 *** had symptoms of chronic intestinal obstruction,including abdominal distension,pain,nausea,or vomiting,and the mean duration of symptoms was 67 mo(range:6-252 mo).Preoperative defecation frequency was 1.5 ± 0.6 times/wk(range:1-2 times/wk).Thirty-two patients underwent total colectomy,and one patient underwent diverting transverse *** was no surgery-related *** histologic examination showed hypoganglionosis or agangliosis in 23 patients and hypoganglionosis combined with visceral neuropathy or myopathy in 10 *** contrast,histology of STC group revealed intestinal neuronal dysplasia type B(n = 6) and visceral myopathy(n = 3).Early postoperative complications developed in six patients with CPO;wound infection(n = 3),paralytic ileus(n = 2),and intraabdominal abscess(n = 1).Defecation frequencies 3 mo after surgery improved to 4.2 ± 3.2 times/d(range:1-15 times/d).Long-term follow-up(median:39.7 mo) was available in 32 patients;all patients had improvements in constipation symptoms,but two patients needed intermittent medication for management of *** 32 patients had distinct

关键词： Constipation Total colectomy Pseudoobstruction Surgical outcome Hypoganglionosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Primary large cell neuroendocrine carcinoma in the common bile duct:First Asian case report

引用

World Journal of Gastroenterology 2014年第47期20卷 18048-18052页

作者： Sung Bae Park Suk Bae moon Young Joon Ryu Jeana Hong Yang Hee Kim Gi Bong chae Seong Kweon Hong Department of Surgery Kangwon National University HospitalKangwon National University School of MedicineChuncheon 200-947South Korea Department of Pathology Kangwon National University HospitalKangwon National University School of MedicineChuncheon 200-947South Korea Department of Pediatrics Kangwon National University HospitalKangwon National University School of MedicineChuncheon 200-947South Korea

Large cell neuroendocrine carcinoma (LCNEC) in the biliary system is a poorly differentiated, high-grade neuroendocrine tumor. These tumors exhibit aggressive behavior and an increased tendency for early nodal and distant metastases. Herein, we report an unusual case of a pure primary LCNEC of the common bile duct (CBD). A 75-year-old female presented with nausea and jaundice. The patient underwent a CBD excision with lymph node dissection. Upon histological and immunohistochemical examination, the tumor exhibited pure large cell-type neuroendocrine features. Metastases were noted in two of the eight lymph nodes. The patient was administered adjuvant chemotherapy. The patient’s cancer recurred 7 mo after surgery, and the patient died from liver failure 5 mo after recurrence. The prognosis of LCNEC of CBD remains poor despite curative resection and adjuvant chemotherapy. The role of additional therapies, such as multimodal treatment including radiation therapy, must be further studied to improve the prognoses of patients.

关键词： Neuro endocrine tumor Large cell neuroendocrine carcinoma Metastases Multimodal treatment Common bile duct

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：