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Boron-containing compounds as labels,drugs,and theranostic agents for diabetes and its complications

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World Journal of Diabetes 2024年第6期15卷 1060-1069页

作者： Marvin A Soriano-Ursúa R Ivan Cordova-ch.vez Eunice D Farfan-García George Kabalka Department of Physiology Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Department of Physiology Instituto Politécnico NacionalMexico City 11340Mexico Department of Biochemistry Instituto Politécnico NacionalMexico City 11340Mexico Department of chemistry The University of TennesseeKnoxvilleTN 37996United States

Diabetes is a disease with a high global *** strategies have failed to limit the advancement and impact of the *** early diagnosis and treatment will require the development of new *** this sense,boroncontaining compounds have been reported as agents with the ability to reduce glycemia and *** have also been used for labeling and measuring carbohydrates and other molecules linked to the initial stages of diabetes and its *** addition,certain boron compounds bind to molecules related to diabetes development and their biological activity in the regulation of elevated ***,it should be noted that some boron compounds appear to exert beneficial effects on diabetes complications such as accelerating wound healing while ameliorating pain in diabetic patients.

关键词： Boron Carbohydrates Metabolism Diabetes Boronodipyrromethene

Highly divergent sympatric lineages of Leptotila verreauxi(Aves:Columbidae)suggest a secondary contact area in the Isthmus of Tehuantepec,Mexico

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Avian Research 2024年第1期15卷 12-21页

作者： Orlando J.Espinosa-ch.vez Adolfo G.Navarro-Sigüenza Hernando Rodríguez-Correa Luis A.Sánchez-González Museo de Zoología“Alfonso L.Herrera” Depto.de Biología EvolutivaFacultad de CienciasUniversidad Nacional Autonoma de MexicoApdo.Postal 70-399CP 04510Ciudad de MexicoMexico Posgrado en Ciencias Biologicas Unidad de PosgradoEdificio D1◦PisoCircuito de PosgradosCiudad UniversitariaUniversidad Nacional Autonoma de MexicoCoyoacanCP 04510CDMXMexico Escuela Nacional de Estudios Superiores Unidad Morelia Universidad Nacional Autonoma de Mexico.Antigua Carretera a Patzcuaro No.8701 Col.Ex Hacienda de San Jose de la HuertaC.P.58190MoreliaMichoacanMexico

Due to a complex geological and biotic history,the Isthmus of Tehuantepec(IT),has been long recognized as a driver for the evolutionary divergence of numerous lowland and highland *** distributed in the lowlands of the American continent,the White-Tipped Dove(Leptotila verreauxi)is a polytypic species with 13 recognized *** of these have been recorded in Mexico,and the distribution of three abuts at the IT,suggesting a contact *** estimate phylogenetic patterns,divergence times and genetic differentiation,we examined two mt DNA(ND2 and COI)and one n DNA(β-fibint 7)*** also used correlative ecological niche models(ENM)to assess whether ecological differences across the IT may have acted as a biogeographical *** estimated paleodistributions during the Middle Holocene,Last Glacial Maximum and Last Interglacial,to evaluate the influence of climate changes on the distribution and demographic *** results showed genetically distinct lineages that diverged approximately 2.5 million years *** and ecological factors may have played a dual role in promoting differentiation,but also in the formation of a secondary contact zone in the southern *** ecological niche comparisons indicated that the ecological niche of sympatric lineages at the IT are not identical,suggesting niches divergence;in addition,environmental niche models across the region indicated no abrupt biogeographic barriers,but the presence of regions with low *** results suggest that genetic differentiation originated by a vicariant event probably related to environmental factors,favored the evolution of different ecological ***,the absence of a biogeographic barrier but the presence of less suitable areas in the contact regions,suggest that secondary contact zones may be also maintained by climatic factors for the eastern group,but also by biotic interactions for the western group.

关键词： Biogeographical boundary Humid and dry forests Isthmus of Tehuantepec Phylogeography Secondary contact

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Solid-liquid extraction for yttrium recovery using porous polymeric resin(XAD-7) functionalized with D_(2)EHPA

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Journal of Rare Earths 2024年第9期42卷 1764-1773,I0005页

作者： P.A.Martínez-Montoya R.G.Sanchez-Alvarado D.Y.Medina-Velazquez M.L.Carrera-Jota P.Garnica-ch.vez A.de J.Morales-Ramirez Higher School of chemical Engineering and Extractive Industries ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico Metropolitan Autonomous University Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center for Research and Technological Innovation CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

The recovery of yttrium is proposed by applying a solid-liquid extraction process using di-2-ethyl hexylphosphoric acid(D2EHPA) as extracting *** extracting agents were supported on a macro porous polymeric resin XAD-7(solid phase).Yttrium ions extraction and discharge tests were performed,firstly from a synthetic aqueous solution of 100 mg/L Y(liquid phase) at 25℃ with *** effects of pH of aqueous solutions bearing yttrium,volume fraction of extracting agents and the solid/liquid(S/L)ratio on the yttrium recovery were *** most favorable conditions for yttrium ions extraction are;20 vol% D_(2)EHPA functionalized resin,pH=1.5 and an S/L ratio of 10 mg/mL The discharge of yttrium ions was done under the same conditions of extraction stage,using a 2 mol/L [H_(2)SO_(4)] as stripping *** to 80% yttrium is extracted,while 75% yttrium is recovered in the striping *** all experiments,the reaction equilibrium is reached after 20 min,and the kinetics for the extraction stage was determined as a second-order ***,experiments were carried out to discharge the yttriumloaded resins,and it has been determined that the best pH value to strip the Y ions is *** tests of extraction and discharge for yttrium ions show that the functionalized resin can work at least five cycles without decreasing its ***,the proposed process was tested in a real solution with Y ions fro m a waste fluorescent la mp powder leached in H_(2)SO_(4),demonstrating the ability to effectively recover yttrium,separating it from various metals from the studied residue.

关键词： Yttrium recovery Rare earth solid-liquid extraction XAD-7 resin Fluorescent lamps recycling Solid-liquid kinetics extraction

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自推进胶囊在小肠中移动时的优化控制

机械工程学报 2024年

作者：廖茂林李智朱佳鹏王泽旭 JOSEPHPáez ch.vez 北京科技大学机械工程学院北京科技大学井下智能控制研究院德累斯顿工业大学动力学研究中心

在消化道检测领域，传统的管线式内镜常给患者带来极大的心理负担与生理不适，胶囊内镜则因驱动方式和控制复杂等原因而难以对小肠部位开展全面而高效的检测。为此，考虑以双边约束的激振胶囊为研究对象，根据小肠结构的变化分别建立了... 详细信息

在消化道检测领域，传统的管线式内镜常给患者带来极大的心理负担与生理不适，胶囊内镜则因驱动方式和控制复杂等原因而难以对小肠部位开展全面而高效的检测。为此，考虑以双边约束的激振胶囊为研究对象，根据小肠结构的变化分别建立了扩张段和狭窄段的小肠-胶囊耦合动力学模型，并以小肠多变的摩擦环境以及对胶囊的包裹程度不同作为不稳定因素，分析了自推进胶囊的动力学行为规律。基于此，同时以胶囊的移动速度、单位能耗和对小肠壁冲击力作为优化目标，采用(Six-Sigma+NSGA-II+Monte-Carlo)组合优化算法获取胶囊可控移动对应的参数组合区间。最终，结合ADAMS动力学仿真与实验测试验证了当采用优化后的参数组合控制自推进胶囊时，可使其实现低能耗低冲击的定速定向移动。

关键词：小肠胶囊非光滑多目标优化运动控制

Standardizing MI-TLIF, a Proposal for a Reproducible Technique

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Open Journal of Modern Neurosurgery 2024年第2期14卷 91-103页

作者： Iván Ulises Sámano López Jesús Alberto Pérez Contreras Emmanuel Cantú ch.vez Diana ch.vez Lizárraga Ana Sofía Peña Blesa Thania Karina Gutiérrez Anchondo Á ngeles Pedregal Ciudad de México México

Background: Minimally invasive transforaminal lumbar interbody fusion (MI TLIF) is a widely known and performed technique, however its versatility among different physicians continues to hinder its replication and results. Therefore, this study aimed to provide a step-by-step surgical guide to perform a safe MI-TLIF, based on the results obtained in patients operated on by a single surgeon over a period of 12 years. Patients and methods: A retrospective, single center, longitudinal, and observational cohort study was conducted with 931 patients who underwent MI TLIF by a single surgeon between 2010 and 2022 using the technique described on this paper, each with a minimum follow-up of 12 months. Criteria included Schizas classification, listhesis according to Meyerding classification, number of levels treated, cage size, and complications (screw repositioning or cerebrospinal fluid leak). Patient clinical outcomes were assessed using the Oswestry Disability Index (ODI), Visual Analog Scale (VAS) for pre- and postoperative radicular pain. Thin slice CT scans were used to assess the progression of the fusion using the Bridwell classification. In the statistical analysis, percentages, median, and interquartile range (IQR) were calculated. Results: Nine hundred and thirty one patients underwent MI TLIF using the technique described, eight hundred and eighty (94.5%) had a single level treated and fifty one (5.5%) had a 2 level procedure (982 levels), an 8mm cage was placed on five hundred and seventeenlevels (52.7%), six hundred and sixty three levels(67.6%) achieved grade I fusion, two hundred and sixty six levels (27.1%) achieved grade II fusion, 52 levels (5.3) achieved grade III fusion and one level (0.1) achieved a grade IV fusion or non-union. Revision surgery was performed on 3 patients (0.3%) for screw repositioning, cerebrospinal fluid leak was present on 2 patients during surgery and treated before closure. VAS scores and ODI were improved at 12 months postop (V

关键词： MITLIF Lumbar Interbody Fusion Technique Pain Relief and Disability

Effect of music therapy on short-term psychological and physiological outcomes in mechanically ventilated patients:A randomized clinical pilot study

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Journal of Intensive Medicine 2024年第4期4卷 515-525页

作者： Mark Ettenberger Rosangela Casanova-Libreros Josefina ch.vez-ch.vez Jose Gabriel Cordoba-Silva William Betancourt-Zapata Rafael Maya Lizeth Alexa Fandino-Vergara Mario Valderrama Ingrid Silva-Fajardo Sandra Milena Hernández-Zambrano SONO-Centro de Musicoterapia BogotáColombia Vice-Rectorate for Research Fundación Universitaria de Ciencias de la SaludBogotáColombia Department of Biomedical Engineering University of Los AndesBogotáColombia Department of Rehabilitation Sociedad de Cirugía de Bogotá Hospital de San JoséBogotáColombia Faculty of Nursing Fundación Universitaria de Ciencias de la SaludBogotáColombia

Background:Elevated anxiety levels are common in patients on mechanical ventilation(MV)and may challenge *** suggests music-based interventions may reduce anxiety during ***,studies inves-tigating specific music therapy techniques,addressing psychological and physiological well-being in patients on MV,are ***:This three-arm randomized clinical pilot study was conducted with MV patients admitted to the intensive care unit(ICU)of Hospital San Joséin Bogotá,Colombia between March 7,2022,and July 11,*** were divided into three groups:intervention group 1(IG1),music-assisted relaxation;intervention group 2(IG2),patient-preferred therapeutic music listening;and control group(CG),standard *** main outcome measure was the 6-item State-Anxiety *** outcomes were:pain(measured with a visual analog scale),resilience(measured with the Brief Resilience Scale),agitation/sedation(measured with the Richmond Agitation-Sedation Scale),vital signs(including heart rate,blood pressure,oxygen saturation,and respiratory rate),days of MV,extubation success,and days in the ***,three patients underwent electroencephalography during the ***:Data from 23 patients were analyzed in this *** age range of the patients was 24.0-84.0 years,with a median age of 66.0 years(interquartile range:57.0-74.0).Of the 23 patients,19 were female(82.6%).No statistically significant differences between the groups were observed for anxiety(P=0.330),pain(P=0.624),resilience(P=0.916),agitation/sedation(P=0.273),length of ICU stay(P=0.785),or vital signs.A statistically significant difference between the groups was found for days of MV(P=0.019).Electroencephalography mea-surements showed a trend toward delta and theta band power decrease for two patients and a power increase on both beta frequencies(slow and fast)in the frontal areas of the brain for one ***:In this pilot study,music therapy did not sig

关键词： Music therapy Mechanical ventilation Intensive care unit Anxiety Pain

Academic Stress Assessment Using Virtual Reality as an Educational Tool in Spine Surgery

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Open Journal of Modern Neurosurgery 2024年第2期14卷 114-123页

作者： Diana ch.vez Lizárraga Jesús Alberto Pérez Contreras Fernando Alvarado Gómez Evelyn Quintero Medina Emmanuel Cantú ch.vez Iván Ulises Sámano López Ana Sofía Peña Blesa Department of Neurosurgery ángeles Pedregal Ciudad de México México Department of Traumatology and Orthopedics Hospital Santa Fe Bogotá Colombia

Introduction: The evaluation of academic stress in medical students and residents is a topic of significant interest, given the considerable challenges they face during their learning process with traditional teaching methods. The use of technologies like virtual reality presents an opportunity to enhance their skills through simulations and training. The main objective of this study is to qualitatively assess the stress levels experienced by medical students and residents by integrating virtual reality into their current learning methods, aiming to improve their ability to manage stressors in their practice. Material and Methods: A questionnaire was conducted with 12 medical students and 12 Traumatology and orthopedics residents. The purpose of the questionnaire was to evaluate the levels of academic stress using the SISCO inventory. The stress levels were calculated by transforming average values into percentages, and the following criteria were assigned: 0 to 33% for Mild Stress, 34 to 66% for Moderate Stress, and 67 to 100% for Deep Stress. Then, a virtual reality class focused on spine surgery was provided. Both medical students and residents were trained using the Non Nocere SharpSurgeon software platform and Oculus Quest 2 virtual reality glasses. At the end of the session, a second questionnaire related to the practice with virtual reality was conducted with the same evaluation criteria and a comparative analysis was carried out. Results: 12 undergraduate students from Hospital Angeles Mexico, CDMX and 12 traumatology and orthopedics residents at Hospital Santa Fe, Bogota were evaluated. The students in CDMX reported an average qualitative stress of 28.50% during habitual practices, which decreased to an average of 14.67% after virtual reality practice. Residents in Bogotá experienced an average qualitative stress of 30.50% with their current learning methods but this reduced to an average of 13.92% after using virtual reality. These findings indicate that t

关键词： Virtual Reality Academic Stress Learning Strategies Spine Surgery Training

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乡村公共数字文化服务标准化推进机理

图书情报研究 2024年第2期17卷 26-38页

作者：田一王锰连忻杰 Amalia Isabel Rivero ch.vez 江苏大学科技信息研究所镇江212013 曼萨尼约市历史档案馆古巴曼萨尼约市87510

[目的/意义]乡村公共数字文化服务在国家层面已然得到政策和法律保障,基本公共文化服务体系初具成效。本研究聚焦乡村公共数字文化服务标准化。[方法/过程]以我国三个公共文化服务体系示范区乡镇服务点的实地调研数据为依据,深入了解乡... 详细信息

[目的/意义]乡村公共数字文化服务在国家层面已然得到政策和法律保障,基本公共文化服务体系初具成效。本研究聚焦乡村公共数字文化服务标准化。[方法/过程]以我国三个公共文化服务体系示范区乡镇服务点的实地调研数据为依据,深入了解乡村公共数字文化服务标准化状况。[结果/结论]从推进主体、推进内容、推进方式三方面构建乡村公共数字文化服务标准化机制的模型,“政府驱动型”、“服务增效型”、“基础保障型”的三重应用模式为政府以标准化完善现代化公共文化服务体系提供了有效参考。

关键词：公共数字文化服务数字乡村服务标准扎根理论

Polygeneration Study of Low-to-Medium Enthalpy Geothermal Reservoirs in Mexico

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Journal of Thermal Science 2021年第3期30卷 1077-1087页

作者： ch.vez osca. GODÍNEZ Francisco Tecnológico Nacional de México/I.T.chihuahua.Av.Tecnológico 2909 C.P.31310ChihuahuaChihuahuaMéxico Instituto de Ingeniería Universidad Nacional Autónoma de MéxicoUNAMC.U.Ciudad de MéxicoC.P.04510México Polo Universitario de Tecnología Avanzada Universidad Nacional Autónoma de MéxicoVía de la Innovación No.410Autopista Monterrey-Aeropuertokm.10 PIITC.P.66629Apodaca Nuevo LeónMéxico

This study combines the thermodynamic analysis of a polygeneration system along with the numerical modelling of the thermal behavior of geothermal reservoirs in Mexico to exploit their *** reservoir was modeled as a porous medium assuming a five-spot well configuration and local thermal *** heat conduction-convection along with the Laplace equations were solved to compute temperature distributions,the useful life and the optimum distance between injection-extraction *** predicted temperature and pressure of the geothermal fluid at the outlet of the reservoir were exploited in the polygeneration system consisting of:(1)a Rankine cycle,(2)an absorption refrigeration cycle,and(3)a heat *** developed approach allows calculating both the optimal distance between injection-extraction wells and the global(utilization)efficiency of six arrangements(each composed by a reservoir connected to a polygeneration system)by assuming that reservoirs have a lifespan of 30 *** also show that:(a)due to the low efficiency of the Rankine cycle,very little thermal energy is converted into electrical one;(b)not only the temperature and the size are important when evaluating the power production performance of reservoirs,but also the permeability plays a fundamental role;(c)the first law efficiency of the polygeneration system ranges from 41.9%to 43.7%;(d)the utilization efficiency of the six arrangements lies in the range between 25.8%and 31%.

关键词： polygeneration system geothermal reservoir local thermal equilibrium low-to-medium enthalpy

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