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Risk factors for acute kidney injury after partial hepatectomy

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World Journal of Hepatology 2017年第18期9卷 815-822页

作者： Luis cesar Bredt Luis Alberto Batista Peres Department of Surgical Oncology and Hepa- tobiliary Surgery University Hospital of Western Paraná State University of Western Paraná Department of Nephrology University Hospital of Western Paraná State University of Western Paraná

To identify risk factors for the occurrence of acute kidney injury (AKI) in the postoperative period of partial hepatectomies. METHODSRetrospective analysis of 446 consecutive resections in 405 patients, analyzing clinical characteristics, preoperative laboratory data, intraoperative data, and postoperative laboratory data and clinical evolution. Adopting the International Club of Ascites criteria for the definition of AKI, potential predictors of AKI by logistic regression were identified. RESULTSOf the total 446 partial liver resections, postoperative AKI occurred in 80 cases (17.9%). Identified predictors of AKI were: Non-dialytic chronic kidney injury (CKI), biliary obstruction, the Model for End-Stage Liver Disease (MELD) score, the extent of hepatic resection, the occurrence of intraoperative hemodynamic instability, post-hepatectomy haemorrhage, and postoperative sepsis. CONCLUSIONThe MELD score, the presence of non-dialytic CKI and biliary obstruction in the preoperative period, and perioperative hemodynamics instability, bleeding, and sepsis are risk factors for the occurrence of AKI in patients that underwent partial hepatectomy.

关键词： Kidney injury Hepatectomy Postoperative Liver Resection

Stroke gets in your eyes: stroke-induced retinal ischemia and the potential of stem cell therapy

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Neural Regeneration Research 2020年第6期15卷 1014-1018页

作者： Chase Kingsbury Matt Heyck Brooke Bonsack Jea-Young Lee cesar V.Borlongan Center of Excellence for Aging and Brain Repair University of South Florida College of Medicine

Stroke persists as a global health and economic crisis,yet only two interventions to reduce stroke-induced brain injury *** the clinic,many patients who experience an ischemic stroke often further suffer from retinal ischemia,which can inhibit their ability to make a functional recovery and may diminish their overall quality of *** this,no treatments for retinal ischemia have been *** both cases,ischemia-induced mitochondrial dysfunction initiates a cell loss cascade and inhibits endogenous brain *** cells have the ability to transfer healthy and functional mitochondria not only ischemic neurons,but also to similarly endangered retinal cells,replacing their defective mitochondria and thereby reducing cell *** this review,we encapsulate and assess the relationship between cerebral and retinal ischemia,recent preclinical advancements made using in vitro and in vivo retinal ischemia models,the role of mitochondrial dysfunction in retinal ischemia pathology,and the therapeutic potential of stem cell-mediated mitochondrial ***,we discuss the pitfalls in classic rodent functional assessments and the potential advantages of laser Doppler as a metric of stroke *** studies evaluated in this review highlight stem cell-derived mitochondrial transfer as a novel therapeutic approach to both retinal ischemia and ***,we posit the immense correlation between cerebral and retinal ischemia as an underserved area of study,warranting exploration with the aim of these treating injuries together.

关键词： laser Doppler MCAO mesenchymal stem cells mitochondrial network mitochondrial transfer ophthalmic artery optic nerve oxygen-glucose deprivation regenerative medicine retinal ganglion cells visual impairment

On the ponderomotive force and the effect of loss reaction on parametric instability

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Chinese Physics B 2007年第2期16卷 558-563页

作者：吴军吴健 cesar La Hoz School of Electronic Information Wuhan University Wuhan 430079 China National Key Laboratory of Electromagnetic Environment China Reseaxch Institute of Radiowsve P.O. Box 6301 Beijing 102206 China Department of Physics University of TromsФ Norway

In this paper, the growth rate, ponderomotive force and the exciting condition for parametric instability are derived by considering the loss reaction using a new method. On the basis of the hydrodynamic equations, we take the production and loss reactions in plasma into account to derive the coupling equations for the electron plasma oscillation and ion acoustic oscillation, and obtain the growth rate for the parametric instability, the ponderomotive force and the exciting condition. The result shows that （a） the production reaction has no effect on the parametric instability, and the effect of loss reaction on the parametric instability is a damping one, （b） the more intensive the external field or pump is, the larger the growth rate is, （c） there exist two modes of the ponderomotive force, i.e. the high frequency mode and the low frequency mode, and （d） when ponderomotive force counteracts the damping force, the oscillations become non-damping and non-driving. The ratio of the electron plasma oscillation to ion acoustic oscillation is independent of the loss reaction and the external field.

关键词： parametric instability loss reaction ponderomotive force

Puma （Puma concolor） epididymal sperm morphometry

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Asian Journal of Andrology 2016年第6期18卷 879-881页

作者： Hernan Cucho Virgilio Alarcon cesar Ordonez Enrique Ampuero Aydee Meza Caries Solere Zootechny School National University of San Atonio Abad del Cusco Postal code 921 Cusco Peru Functional Biology and Physical Anthropology Department University of Valencia C/. Dr Moliner 50 46100 Burjassot Valencia Spain Proiser R+D S.L. Scientific Park of the University of Valencia 46980 Paterna Spain

The Andean puma （Puma concolor） has not been widely studied, particularly in reference to its semen characteristics. The aim of the present study was to define the morphometry of puma sperm heads and classify their subpopulations by cluster analysis. Samples were recovered postmortem from two epididymides from one animal and prepared for morphological observation after staining with the Hemacolor kit. Morphometric data were obtained from 581 spermatozoa using a CASA-Morph system, rendering 13 morphometric parameters. The principal component （PC） analysis was performed followed by cluster analysis for the establishment of subpopulations. Two PC components were obtained, the first related to size and the second to shape. Three subpopulations were observed, corresponding to elongated and intermediate-size sperm heads and acrosomes, to large heads with large acrosomes, and to small heads with short acrosomes. In conclusion, puma spermatozoa showed no uniform sperm morphology but three clear subpopulations. These results should be used for future work in the establishment of an adequate germplasm bank of this species.

关键词： principal component analysis puma sperm morphometry subpopulation wild animal

Influence of variables related to soil weathering on the geomechanical performance of tropical soils

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第9期15卷 2423-2440页

作者： Rodrigo cesar Pierozan Gregorio Luís Silva Araújo Ennio Marques Palmeira Celso Romanel Department of Civil Engineering Federal Institute of EducationScienceand Technology of RondoniaPorto VelhoROBrazil Department of Civil and Environmental Engineering University of BrasiliaBrasiliaDFBrazil Department of Civil and Environmental Engineering Pontifical Catholic University of Rio de JaneiroRio de JaneiroRJBrazil

This paper presents an experimental and analytical investigation of the influence of variables related to soil weathering on the geomechanical performance of sand-silt mixtures containing lateritic soils,*** weathered tropical soils with the influence of interparticle *** sand-silt mixtures containing different relative proportions between uniform sand and lateritic soil were produced,and geomechanical soil characterization tests were *** on the results,a transition from a primarily coarse-to a fine-grained prevailing soil structure was found to cause considerable impact on the geomechanical performance of these soils,as evidenced by design variables related to soil mineralogy and size distribution ***,fines contents of both individual soil particles and soil aggregations were found to correlate with experimental results,while the relative proportion between sesquioxides(aluminum,and iron oxides),and silica,***-silica ratios(SSR^(-1)),facilitated estimates concerning changes in geomechanical ***,the application of the sandsilt mixtures containing lateritic soil on soil walls reinforced with polymeric strips was also evaluated,further emphasizing the potential advantages of adopting variables related to soil weathering on design guidelines concerning tropical soils.

关键词： Sesquioxides-silica ratio Tropical soils Sand-silt mixtures Lateritic soil Reinforced soil walls

The hydrolysis degree of agave syrup modulates its functional properties: Impact on metabolic responses and oxidative stress in C57BL/6 mice

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FOOD BIOSCIENCE 2023年第3期53卷 2535-2542页

作者： Cardona-Herrera, Roman Franco-Robles, Elena Quinones-Munoz, Tannia Alexandra Ozuna, cesar Univ Guanajuato Posgrad Biociencias Div Ciencias Vida Campus Irapuato Salamanca Irapuato 36500 Guanajuato Mexico Univ Guanajuato Dept Vet & Zootecnia Div Ciencias Vida Irapuato 36500 Guanajuato Mexico Consejo Nacl Human Ciencias & Tecnol CONAHCYT Ctr Invest & Asistencia Unidad Tecnol Alimentaria Disen Estado Jalisco CIATEJ Camino Arenero 1227 Zapopan 45019 Jalisco Mexico Univ Guanajuato Dept Alimentos Div Ciencias Vida Irapuato 36500 Guanajuato Mexico Univ Guanajuato Dept Alimentos Posgrad Biociencias Div Ciencias Vida Salamanca 36500 Guanajuato Mexico

Nowadays, agave syrup (AS) is a controversial sweetener due to its high fructose content. However, the hydrolysis process to which AS is subjected could contribute to improving its functional properties. This work aimed to evaluate the relationship between the degree of hydrolysis (DH) of AS (95%: AS95, 88%: AS88, and 50%: AS50) and its functional properties. In addition, the impact of these properties on weight gain, blood biochemical parameters, and oxidative stress (lipids and proteins) was studied in C57BL/6 mice. By HPLC analysis, the main polyphenols identified in AS were catechin, chlorogenic acid, caffeic acid, vanillin, quercetin, naringin, rutin, ellagic acid, and gallic acid. As the DH of AS increased, its fructose concentration increased (p 0.05) in comparison to the control (water). However, mice drinking AS50 solutions showed a decrease (p < 0.05) in weight gain (35%), cholesterol (6%), triglycerides (18-22%), and oxidative stress in lipids (63%) and proteins (44%) compared to mice drinking AS88 and AS95 solutions.

关键词： Natural sweeteners Fructose Fructans Polyphenols Antioxidant capacity

The impact of anti-tobacco legislation on birth weight in Peru

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Global Health Research and Policy 2020年第1期5卷 396-405页

作者： Patricia Mallma cesar Carcamo Jay S.Kaufman Epidemiology HIV and STD UnitSchool of Public Health and AdministrationUniversidad Peruana Cayetano HerediaLimaPeru Department of Epidemiology Biostatisticsand Occupational HealthMcGill UniversityMontrealCanada

Background:Tobacco exposure remains a significant issue for public health,especially for pregnant *** increases the risk for premature labor,low birth weight and small for gestational age(SGA),among other *** reduce these risks,many countries have enacted public policies to curb tobacco *** enacted anti-tobacco laws that forbid smoking in public places,require prevention text and images in products and publicity,along with restriction of sales to *** evaluated the effect of the implementation of this law on newborn outcomes:birth weight,prematurity and ***:This was a quasi-experimental study that utilized data from the Peruvian Live Birth *** born to mothers from urban areas were the intervention group,while children born to mothers from rural areas were considered the control *** singletons with information on birth weight and gestational age,born to mothers aged 12 to 49 years were included in the *** addition,newborns with birth weights greater than+4 standard deviations(SD)or less than−4 SD from the gestational age-specific mean were *** measure the effect of legislation on birth weight we performed a difference in differences ***:A total of 2,029,975 births were included in the *** adjusting for characteristics of the mother and the child,and contextual variables,the anti-tobacco law in Peru reduced the incidence of prematurity by 30 cases per 10,000 live births(95%CI:19 to 42).Conclusions:The reform had negligible effects on overall birth weights and on the incidence of *** modest result suggests the need for a more aggressive fight against tobacco,prohibiting all types of advertising and promotion of tobacco products,among others measures.

关键词： Tobacco control Peru Low birth weight Prematurity and small gestational age

A hybrid method to select morphometric features using tensor completion and F-score rank for gifted children identification

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Science China(Technological Sciences) 2021年第9期64卷 1863-1871页

作者： ZHANG Jin FENG Fan HAN TianYi DUAN Feng SUN Zhe CAIAFA cesar F. SOLÉ-CASALS Jordi College of Computer Science Nankai UniversityTianjin 300350China Department of Artificial Intelligence Nankai UniversityTianjin 300350China Computational Engineering Applications Unit Head Office for Information Systems and CybersecurityRIKEN351-0198 SaitamaJapan Instituto Argentino de Radioastronomía-CCT La Plata CONICET/CIC-PBA/UNLP1894 V.ElisaArgentina Department of Psychiatry University of CambridgeCambridge CB20SZUnited Kingdom Data and Signal Processing Group University of Vic-Central University of Catalonia08500 VicCataloniaSpain

Gifted children are able to learn in a more advanced way than others, probably due to neurophysiological differences in the communication efficiency in neural pathways. Topological features contribute to understanding the correlation between the brain structure and intelligence. Despite decades of neuroscience research using MRI, methods based on brain region connectivity patterns are limited by MRI artifacts, which therefore leads to revisiting MRI morphometric features, with the aim of using them to directly identify gifted children instead of using brain connectivity. However, the small, high-dimensional morphometric feature dataset with outliers makes the task of finding good classification models challenging. To this end, a hybrid method is proposed that combines tensor completion and feature selection methods to handle outliers and then select the discriminative features. The proposed method can achieve a classification accuracy of 93.1%, higher than other existing algorithms, which is thus suitable for the small MRI datasets with outliers in supervised classification scenarios.

关键词： gifted children identification morphometric features tensor completion feature selection

Multitemporal landslide inventory analysis of an intertropical mountain in west-central Mexico——Basis for hazard management

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Journal of Mountain Science 2022年第6期19卷 1650-1669页

作者： Alejandro cesar VALDES CARRERA Manuel E.MENDOZA Teodoro CARLÓN ALLENDE Jose Luis MACIAS Centro de Investigaciones en Geografia Ambiental Universidad Nacional Autonoma de MexicoMorelia 58190Mexico Consejo Nacional de Ciencia y Tecnologia-Instituto de Geofisica-Unidad Michoacan Universidad Nacional Autonoma de MexicoMorelia 58190Mexico Instituto de Geofisica-Unidad Michoacan Universidad Nacional Autonoma de MexicoMorelia 58190Mexico

Landslides in intertropical mountainous areas of Mexico are a natural hazard that could potentially generate a disaster. Despite this, many areas lack landslide inventories, making it difficult to monitor and efficiently manage the associated risks for local populations. For this reason, the aim of this research was to undertake a multitemporal landslide inventory and analyze its conditioning factors in the Pico de Tancítaro stratovolcano, which, in recent decades, has presented several high-risk geomorphological events with disastrous consequences for nearby localities. The spatial distribution of landslides and its conditioning factors were mapped at a 1:50,000 scale for the 1995-2020 period, through visual interpretation of orthophotos and satellite images(Landsat, SPOT, and SENTINEL). The conditioning factors that link the most to landslides were Quaternary andesite and basaltic andesite rocks;volcanic cones, mountain river valleys, and very steep to steep slopes(30° to >45°), oriented to the South, North, and East;Andosols and Leptosols;and the oyamel fir and mixed forests. 505 landslide events classified into slides and flows that occurred in 1995, 2004, 2010, and 2015 were identified. New scars generated by the reactivation of landslide processes were also observed. The landslides in the study area were triggered by torrential rains caused by hurricanes and tropical storms;such as hurricanes Alex and Patricia. The inventory and analysis of conditioning factors highlighted the distribution and dynamics of slides and flows in the study area. In addition, the most important factors for studies of landslide susceptibility, hazards, and risks in the Pico de Tancítaro stratovolcano were identified, contributing to the management of geomorphological risks in intertropical mountain areas.

关键词： Geomorphology Mass wasting Natural hazards Pico de Tancítaro stratovolcano Risk management