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肛门外括约肌的萎缩和缺损检查:三维肛门超声内镜与肛内磁共振成像检查的比较

世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 4-5页

作者： cazemier m. Terra m. P. Stoker J. 陈云茹(译) 史敏(校) VU m.dical Center De Boelelaan 1117 1007 MB Amsterdam Netherlands 不详

PURPOSE: Using endoanalm.gnetic resonance im.ging, atrophy of the external anal sphincter can be established. This aspect has not been thoroughly investigated using three-dim.nsional anal endosonography. The purpose of this study was to com.are prospectively three-dim.nsional anal endosonography to m.gnetic resonance im.ging in the detection of atrophy and defects of the external anal sphincter in patients with fecal incontinence. In addition, we com.ared both techniques for anal sphincter thickness and length m.asurem.nts. m.TERIALS AND m.THODS: Patients with fecal incontinence underwent three-dim.nsio-nal anal endosonography and m.gnetic resonance im.ging. Im.ges of both endolum.nal techniques were evaluated for atrophy and defects of the external anal sphincter. External anal sphincter atrophy scoring with three-dim.nsional anal endosonography depended on the distinction of the external anal sphincter and its reflectivity. External anal sphincter atrophy scoring with m.gnetic resonance im.ging depended on the am.unt of m.scle and the presence of fat replacem.nt. Atrophy score was defined as none, m.derate, and severe. A defect was defined at anal endosonography by a hypoechogenic zone and at m.gnetic resonance im.ging as a discontinuity of the sphincteric ring and/or scar tissue. Differences between three-dim.nsional anal endosonography and m.gnetic resonance im.ging for the detection of external anal sphincter atrophy and defects were calculated. In addition, we com.ared external anal sphincter thickness and length m.asurem.nts in three-dim.nsional anal endosonography and m.gnetic resonance im.ging. RESULTS: Eighteen patients were included (m.dian age, 58 years; range, 27- 80; 15 wom.n). Three-dim.nsional anal endosonography and m.gnetic resonance im.ging did not significantly differ for the detection of external anal sphincter atrophy (P = 0.25) and defects (P = 0.38). Three-dim.nsional anal endosonography dem.nstrated atrophy in 16 patients, m.gnetic resonance

关键词：磁共振成像检查肛门外括约肌超声内镜肛内三维缺损大便失禁前瞻性比较肌萎缩测量技术

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Elastic band ligation of hem.rrhoids:Flexible gastroscope or rigid proctoscope?

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World Journal of Gastroenterology 2007年第4期13卷 585-587页

作者： m.cazemier RJF Felt-Bersm. m. Cuesta CJJ m.lder Departm.nt of Gastroenterology and Hepatology VU University Medical Center Amsterdam The Netherlands Departm.nt of Gastrointestinal Surgery VU University Medical Center Amsterdam The Netherlands Departm.nt of Gastroenterology and Hepatology VU University Medical Center.Amsterdam The Netherlands

AIm. To com.are dgid proctoscope and flexible endoscope for elastic band ligation of internal hem.rrhoids. m.THODS： Patients between 18 and 80 years old, with chronic com.laints （blood loss, pain, itching or prolapse） of internal hem.rrhoids of grade 1-91, were random.zed to elastic band ligation by rigid proctoscope or flexible endoscope （preloaded with 7 bands）. Patients were retreated every 6 wk until the cessation of com.laints. Evaluation by three-dim.nsional anal endosonography was perform.d. RESULTS： Forty-one patients were included （m.dian age 52.0, range 27-79 years, 20 m.n）. Nineteen patients were treated with a rigid proctoscope and twenty two with a flexible endoscope. Twenty-nine patients had grade I hem.rrhoids, 9 patients had grade 11 hem.rrhoids and 3 patients had grade 91 hem.rrhoids. All patients needed a m.nim.m.of 1 treatm.nt and a m.xim.m.of 3 treatm.nts. A m.dian of 4.0 bands was used in the rigid proctoscope group and a m.dian of 6.0 bands was used in the flexible endoscope group （P 〈 0.05）. Pain after ligation tended to be m.re frequent in patients treated with the flexible endoscope （first treatm.nt： 3 vs 20 patients, P 〈 0.05）. Three- dim.nsional endosonography showed no sphincter defects or alterations in subm.cosal thickness. CONCLUSION： Both techniques are easy to perform. well tolerated and have a good and fast effect. It is easier to perform.m.re ligations with the flexible endoscope. Additional advantages of the flexible scope are the m.neuverability and photographic docum.ntation. However, treatm.nt with the flexible endoscope m.ght be m.re painful and is m.re expensive.

关键词： Hem.rrhoids Barron ligation Rigid scope Endoscope Anal endosonography

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月桂酰乳酰乳酸钠对感染亚临床产气荚膜梭菌肉鸡生产性能和肠道健康的影响

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饲料博览 2011年第2期21卷 34-34页

作者： Lensing m.Vander K J D Fabri T cazemier A Else A J

产气荚膜梭菌属革兰氏阳性菌,是一种家禽肠道致病菌。由于产气荚膜梭菌亚临床感染常导致肠黏膜损害,降低营养物质的消化,降低生产性能,应采取一种有效的措施控制产气荚膜梭菌的过度生长。为此,本文旨在研究月桂酰乳酰乳酸钠作为一种饲... 详细信息

产气荚膜梭菌属革兰氏阳性菌,是一种家禽肠道致病菌。由于产气荚膜梭菌亚临床感染常导致肠黏膜损害,降低营养物质的消化,降低生产性能,应采取一种有效的措施控制产气荚膜梭菌的过度生长。为此,本文旨在研究月桂酰乳酰乳酸钠作为一种饲料添加剂防止产气荚膜梭菌在肉鸡肠道内定植(LauL)的药效测定。首先,将月桂酰乳酰乳酸钠与感染产气荚膜梭菌肉鸡的月桂酸单体甘油二脂(m.G)和月桂酸游离脂肪酸(LauL)相比,产气荚膜梭菌损害度16分的结果表明,m.G和LauL两者都有降低损害程度的效果。考虑到体增重和死亡率,LauL比m.G更有效。因此,剂量反应研究目的是确定最佳LauL添加量。试验结果表明,LauL的剂量高于15%,对损害度和死亡率起到预期的积极作用。不添加任何剂量的LauL,生长性能较好。在第3次试验中,将LauL的效果与限制肠道内细菌活性的商业化产品(Arom.biotic波尔60)或限制球虫病的细菌(化学抗球虫药,Clinacox)相比。该产品并没有减少损害的数目和严重程度,且对生产性能无影响。因此,尽管在试验1和试验2中,高于0.15%剂量的LauL产生了显著的作用效果,但是添加月桂酰乳酰乳酸钠并不能降低产气荚膜梭菌在肉鸡体内的定植,故在试验3中并未产生效果。但为进一步研讨月桂酰乳酰乳酸钠作为潜在的添加剂对减少肉鸡产气荚膜梭菌激发的免疫反应的研究,提供了科学依据。

关键词：产气荚膜梭菌月桂酰乳酰乳酸钠肠道健康肉鸡

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月桂酰乳酰乳酸钠对感染亚临床产气荚膜梭菌肉鸡生产性能和肠道健康的影响

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饲料博览 2010年第12期20卷 49-49页

作者： Lensing m.Van der Klis J D Fabri T cazemier A Else A J

产气荚膜梭茵属革兰氏阳性菌，是一种家禽肠道致病菌。由于产气荚膜梭菌亚临床感染常导致肠黏膜损害，降低营养物质的消化，降低生产性能，应采取一种有效的措施控制产气荚膜梭茵的过度生长。

关键词：产气荚膜梭菌肉鸡生产性能亚临床感染肠道健康乳酸钠月桂酰革兰氏阳性菌肠道致病菌

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