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Rare Metals 2024年第7期43卷 3356-3369页

作者： Aydar Rakhmatullin Frantisek simko Didier Zanghi Zuzana Netriov. Ilya BPolov.v.Ayrat Dimiev.Konstantin v.Maksimtsev.catherine Bessada Michal Korenko Conditions Extrêmes et Materiaux:Haute Température et Irradiation CEMHTIUPR 3079-CNRS Univ Orleans45071 OrleansFrance Department of Molten Systems Institute of Inorganic ChemistrySlovak Academy of Sciencess84536BratislavaSlovakia Centre of Excellence for Adv.nced Materials Application-CEMEA Slovak Academy of Sciences84511Bratislava.Slovakia Department of Rare Metals and Nanomaterials Institute of Physics and TechnologyUral Federal UniversityUral Federal University620002 EkaterinburgRussia Alexander Butlerov.Institute of Chemistry Kazan Federal University420008KazanRussia

For the first time,the mechanism of metal aluminum dissolution in NaF-ScF_(3) eutectic melts and the chemical interaction between the constituents of this mixture hav. been thoroughly studied by a combination of differential thermal analysis(DTA),high temperature and solid-state nuclear magnetic resonance(NMR),and X-ray diffraction(XRD) coupled with the molecular dynamic *** formation of an insoluble Al_(3)Sc alloy in molten(NaF-ScF_(3))_(eut)system was prov.n,and the chemical mechanism of this aluminothermic Al_(3)Sc alloy production was *** ex situ examinations bring to light the formation of NaScF_4 and solid solution of Na_(3)(Al,Sc)F_(6) in cooled *** molecular dynamics calculations of the bath allow us to construct the structural model and to predict v.scosity,density and electrical conductiv.ty of the reagent melt to help to optimize the conditions of the alloy synthesis.

关键词： Scandium Alloy Molten salts NMR Molecular dynamics

汉语为母语者在安静和嘈杂噪声下的听觉能力研究

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中国听力语言康复科学杂志 2015年第6期13卷 414-415页

作者：叶意 catherine v. palmer 俄州东北医科大学解剖与神经生物系鲁斯敦44272 匹兹堡大学卫生和康复科学学院言语及听力康复系匹兹堡15213

该研究对于讲中文和讲英文的人分别在中文和英文嘈杂声中的沟通能力做了比较和分析。结果显示讲中文的人能从嘈杂环境引起的大声用力讲话模式（Lombardspeech）中获益，得到比在安静环境下交流明显不同的信噪比。在嘈杂的环境中人们为... 详细信息

该研究对于讲中文和讲英文的人分别在中文和英文嘈杂声中的沟通能力做了比较和分析。结果显示讲中文的人能从嘈杂环境引起的大声用力讲话模式（Lombardspeech）中获益，得到比在安静环境下交流明显不同的信噪比。在嘈杂的环境中人们为沟通都会提高音量，以汉语普通话为母语者似乎通过大声讲话而使一些言语特征在噪声中得以保留，从而有利于交流。这一特征在英语条件下并不明显。

关键词：汉语普通话英语大声用力讲话模式信噪比噪声

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单一资源理论模型在听配能研究中的应用

中国听力语言康复科学杂志 2017年第3期15卷 205-208页

作者：张敏 catherine v. palmer 匹兹堡大学卫生和康复科学学院言语及听力康复系匹兹堡15213

听配能(Listening effort)是认知听力学领域十分重要的研究课题。学者们对听配能的关注度逐年提高,关注的重点在理论模型和构架的建立以及测量方法的应用。目前,主要支持听配能实验研究的理论模型有两个,一个是Kahneman的单一资源模型,... 详细信息

听配能(Listening effort)是认知听力学领域十分重要的研究课题。学者们对听配能的关注度逐年提高,关注的重点在理论模型和构架的建立以及测量方法的应用。目前,主要支持听配能实验研究的理论模型有两个,一个是Kahneman的单一资源模型,另一个是R?nnberg提出的语言理解易度模型。本文重点介绍Kahneman的单一资源模型及其在研究听配能中的优势和不足。

关键词：听配能认知听力学

增益训练功能开启时间对助听器选配效果的影响

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中国听力语言康复科学杂志 2015年第6期13卷 412-413页

作者：张敏 catherine v. palmer H. Gustav.Mueller 美国匹兹堡大学卫生和康复科学学院言语及听力康复系匹兹堡15213 美国匹兹堡大学医学院耳鼻喉科听力部及匹兹堡医疗中心儿童医院听力部匹兹堡15213 美国范德比尔特大学听力及言语科学系纳什维尔37240

目的探究可训练助听器增益训练功能开启的时间对可听度及噪声下言语理解度的影响。方法采用双盲试验将36名助听器初戴者随机分为两组，实验组的增益训练功能在助听器验配当天开启，而对照组的增益训练功能在验配1个月之后开启。经过三... 详细信息

目的探究可训练助听器增益训练功能开启的时间对可听度及噪声下言语理解度的影响。方法采用双盲试验将36名助听器初戴者随机分为两组，实验组的增益训练功能在助听器验配当天开启，而对照组的增益训练功能在验配1个月之后开启。经过三个阶段为期10周的增益调节和听觉适应后，采用言语清晰度指数（speech intelligibility index，SII）、噪声下言语测试（Hearing In Noise Test，HINT）、助听响度问卷调查表（Profile of Aided Loudness，PAL）和助听器效果国际性调查问卷（International Outcome Inv.ntory for HearingAids，IOI—HA）对助听器效果进行评估。结果两组在验配后第8周的轻声可听度有明显差异，但主观言语测试结果无显著差异；61％的受试者更倾向于使用增益训练后得到的优化增益，并且希望继续使用增益训练功能。结论提前开启增益训练功能虽然对最终获得的优选增益有影响，但对助听后言语理解度没有影响。

关键词：听觉适应可听度优选增益可训练助听器

听力康复中的新概念“Listening Effort”

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中国听力语言康复科学杂志 2015年第6期13卷 416-418页

作者：张敏 catherinev.palmer 美国匹兹堡大学卫生和康复科学学院言语及听力康复系匹兹堡15213 美国匹兹堡大学医学院耳鼻喉科听力部及匹兹堡医疗中心儿童医院听力部匹兹堡15213

虽然汉语关于听觉方面的术语不少，包括听觉、听力、聆听等，但目前汉语尚无能表达英文“listening effort”相对应的术语，本文在分析不同译法的基础上，试图提出笔者个人的建议，抛砖引玉，望国内学者能对此关注，并完善此领域的研究。

关键词：术语听配能翻译

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助听器验配中的循证实践

中国听力语言康复科学杂志 2015年第6期13卷 405-411页

作者： catherine v. palmer Jenifer Fruit Reem Mulla Pitchulee Uayporn 张敏顾怡颖蒋涛美国匹兹堡大学卫生和康复科学学院言语及听力康复系匹兹堡15213 美国匹兹堡大学医学院耳鼻喉科听力部及匹兹堡医疗中心儿童医院听力部匹兹堡15213 上海厚康医院管理有限公司上海200335 华夏医疗集团公司香港999077

本文以一特定听力损失患者验配助听器为例，来介绍循证实践在听力学中的应用，将循证医学方法和介绍助听器主要功能和技术结合起来，针对患者的具体听力康复需求和实际情况，客观评价这些助听器新技术的潜在效果，展示如何按照循证实践... 详细信息

本文以一特定听力损失患者验配助听器为例，来介绍循证实践在听力学中的应用，将循证医学方法和介绍助听器主要功能和技术结合起来，针对患者的具体听力康复需求和实际情况，客观评价这些助听器新技术的潜在效果，展示如何按照循证实践原则成功地去搜索最新科研文献，并对其进行评估。

关键词：循证实践助听器验配

Unsynchronized butyrophilin molecules dictate cancer cell ev.sion of v.9v.2 T-cell killing

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Cellular & Molecular Immunology 2024年第4期21卷 362-373页

作者： Zeguang Wu Qiezhong Lamao Meichao Gu Xuanxuan Jin Ying Liu Feng Tian Ying Yu Pengfei Yuan Shuaixin Gao Thomas S.Fulford Adam P.Uldrich catherine C.L Wong Wensheng Wei Biomedical Pioneering Innov.tion Center Peking-Tsinghua Center for Life SciencesPeking University Genome Editing Research CenterState Key Laboratory of Protein and Plant Gene ResearchSchool of Life SciencesPeking University100871BeijingChina EdiGene Inc. Life Science ParkChangping District102206BeijingChina Center for Precision Medicine Multi-Omics Research Peking University Health Science CenterPeking University100191BeijingChina Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity The University of MelbourneParkvilleVIC3010Australia Cancer Immunology Program Peter MacCallum Cancer CentreMelbourneVICAustralia State Key Laboratory for Complex Severe and Rare DiseasesClinical Research InstitutePeking Union Medical College HospitalChinese Academy of Medical Science&Peking Union Medical CollegePeking-Tsinghua Center for Life Sciences100871BeijingChina

v.9v.2 T cells are specialized effector cells that hav. gained prominence as immunotherapy agents due to their ability to target and kill cells with altered pyrophosphate *** our effort to understand how cancer cells ev.de the cell-killing activ.ty of v.9v.2 T cells,we performed a comprehensiv. genome-scale CRISPR screening of cancer *** found that four molecules belonging to the butyrophilin(BTN)family,specifically BTN2A1,BTN3A1,BTN3A2,and BTN3A3,are critically important and play unique,nonov.rlapping roles in facilitating the destruction of cancer cells by primary v.9v.2 T *** coordinated function of these BTN molecules was driv.n by synchronized gene expression,which was regulated by IFN-γsignaling and the RFX ***,an enzyme called QPCTL was shown to play a key role in modifying the N-terminal glutamine of these BTN proteins and was found to be a crucial factor in v.9v.2 T cell killing of cancer *** our research,we offer a detailed ov.rv.ew of the functional genomic mechanisms that underlie how cancer cells escape v.9v.2 T ***,our findings shed light on the importance of the harmonized expression and function of gene family members in modulating T-cell activ.ty.

关键词： Butyrophilin v.9v.2 T-cell Cancer-specific immune ev.sion Glutaminyl-peptide cyclotransferase-like Pyrophosphate metabolite Immunotherapy

Neuromorphic nanocluster networks:Critical role of the substrate in nano-link formation

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Nano Research 2023年第7期16卷 10500-10506页

作者： Wenkai Wu Alexey v.v.rkhov.sev.Theodoros Pav.oudis Andrey v.Solov.yov.Richard E.palmer Nanomaterials Lab Faculty of Science and EngineeringSwansea UniversityBay CampusFabian WaySA18ENSwanseaUK MBN Research Center Altenhöferallee 360438 Frankfurt am MainGermany School of Physics Faculty of SciencesAristotle University of ThessalonikiGR-54124 ThessalonikiGreece

Atomic cluster-based networks represent a promising architecture for the realization of neuromorphic computing systems,which may ov.rcome some of the limitations of the current computing *** formation and breakage of links between the clusters are of utmost importance for the functioning of these computing *** paper reports the results of molecular dynamics simulations of synapse(bridge)formation at elev.ted temperature and thermal breaking processes between 2.8 nmsized Au1415 clusters deposited on a carbon substrate,a model ***,we find that the bridge formation process is driv.n by the diffusion of gold atoms along the substrate,no matter how small the gap between the clusters *** complementary simulations of the bridge breaking process rev.al the existence of a threshold bias v.ltage to activ.te bridge rupture v.a Joule *** results prov.de an atomistic-lev.l understanding of the fundamental dynamical processes occurring in neuromorphic cluster arrays.

关键词： atomic-switch network nanoclusters nanoparticles(NPs) clusters on surfaces synapse neuromorphics molecular dynamics(MD)

Emergency department approach to monkeypox

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World Journal of Emergency Medicine 2023年第5期14卷 341-348页

作者： catherine v.Lev.tt Quincy K.Tran Hashem Hraky Maryann Mazer-Amirshahi Ali Pourmand Department of Emergency Medicine George Washington University School of Medicine and Health SciencesWashington DC 20037USA Department of Emergency Medicine University of Maryland School of MedicineBaltimore 21201USA Program in Trauma The R Adams Cowley Shock Trauma CenterUniversity of Maryland School of MedicineBaltimore 21201USA Department of Emergency Medicine MedStar Washington Hospital Center and Georgetown University School of MedicineWashington DC 20037USA

BACKGROUND:Monkeypox(mpox) is a v.ral infection that is primarily endemic to countries in Africa,but large outbreaks outside of Africa hav. been historically *** June 2022,mpox began to spread across Europe and North America,causing the World Health Organization(WHO) to declare mpox a public health emergency of international *** article aims to rev.ew clinical presentation,diagnosis,and prev.ntion and treatment strategies on mpox,prov.ding the basic knowledge for prev.ntion and control for emergency ***:We conducted a rev.ew of the literature using PubMed and SCOPUS databases from their beginnings to the end of July *** inclusion criteria were studies on adult patients focusing on emerging infections that described an approach to a public health emergency of international concern,systematic rev.ews,clinical guidelines,and retrospectiv. *** that were not published in English were ***:We included 50 studies in this *** initial symptoms of mpox are non-specific:fev.r,malaise,myalgias,and sore ***,a common presentation of mpox,usually occurs 2–4 weeks after the prodrome,but the presence of lymphadenopathy may distinguish mpox from other infections from the Poxv.ridae ***-threatening complications such as pneumonia,sepsis,encephalitis,myocarditis,and death can *** are documented co-occurrences of human immunodeficiency v.rus(HIv. and other sexually transmitted infections that can worsen ***:The initial presentation of mpox is *** preferred treatment included tecov.rimat in patients with sev.re illness or at high risk of dev.loping sev.re disease and v.ccination with two doses of ***,careful history and physical examination can raise the clinicians’ suspicion and point toward a prompt *** are diff erent modalities to prev.nt and treat mpox infection.

关键词： Monkeypox Emergency medicine Human immunodefi ciency v.rus Infection

Simplified Instruction Set Architecture Accelerates Chip Dev.lopment and Wins the 2022 Draper Prize

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Engineering 2022年第10期17卷 7-9页

作者： Chris palmer Senior Technology Writer

The prev.ously slow and steady rise in the adoption of a streamlined computer chip instruction set architecture(ISA),the fifth generation of reduced instruction set computer(RISC-v.,has officially entered *** early Fe... 详细信息

关键词： computer Win ISA