Bac.ground c.rdiovasc.lar disease (c.D) is mainly c.used by atherosc.erosis,for whic. dyslipidemia (i.e. high (V)LDL-c.olesterol (c.,high triglyc.rides and low HDLc.is a major risk fac.or. To reduc. the risk to develo...
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Bac.ground c.rdiovasc.lar disease (c.D) is mainly c.used by atherosc.erosis,for whic. dyslipidemia (i.e. high (V)LDL-c.olesterol (c.,high triglyc.rides and low HDLc.is a major risk fac.or. To reduc. the risk to develop c.D,patients with dyslipidemia are usually treated with lipid-lowering drugs inc.uding statins and fibrates.
Dear Editors,Ec.lizumab is a therapeutic.c.mplement c. inhibitor approved for the treatment of atypic.l hemolytic.uremic.syndrome(aHUS),paroxysmal noc.urnal proteinuria(PNH),generalized myasthenia gravis and neuromyel...
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Dear Editors,Ec.lizumab is a therapeutic.c.mplement c. inhibitor approved for the treatment of atypic.l hemolytic.uremic.syndrome(aHUS),paroxysmal noc.urnal proteinuria(PNH),generalized myasthenia gravis and neuromyelitis optic. spec.rum *** dosing of ec.lizumab is important to ensure c.mplete c.mplement *** ac.ivity is often monitored by measuring either formation of the c. ac.ivation produc. c.b-9 in vitro using an ELISA,independent of red blood c.lls,or by hemolytic.assays measuring hemoglobin release from *** approac.es allow analysis of c.mplement ac.ivation via the c.assic.l(c.)and alternative(AP)pathways.
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