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Bridging the gap:Unveiling the crisis of physical inactivity in inflammatory bowel diseases

World Journal of Gastroenterology 2024年第10期30卷 1261-1265页

作者： Remus Stafie Ana-Maria Singeap Adrian Rotaru carol Stanciu Anca Trifan Department of Gastroenterology Faculty of Medicine“Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania Institute of Gastroenterology and Hepatology “St.Spiridon”University HospitalIasi 700111Romania

In this editorial we comment on the article titled“Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity:The BE-FIT-IBD study”published in a recent issue of the World Journal of Gastroen-terology 2023;29(41):5668-5682.Inflammatory bowel diseases(IBD)are emerging as a significant global health concern as their incidence continues to rise on a global scale,with detrimental impacts on quality of life.While many advances have been made regarding the management of the disease,physical inactivity in these patients represents an underexplored issue that may hold the key for further and better understanding the ramifications of IBD.Chronic pain,fatigue,and fear of exacerbating symptoms promotes physical inactivity among IBD patients,while the lack of clear guidelines on safe exercise regimens contributes to a norm of physical inactivity.Physical activity(PA)is accepted to have a positive effect on disease outcomes and quality of life,while inactivity exacerbates comorbidities like cardiovascular disease and mental health disorders.The“BE-FIT-IBD”study,focusing on PA levels and barriers in IBD patients of Southern Italy,revealed that a significant proportion(42.9%)were physically inactive.This lack of PA is attributed to barriers such as fear of flare-ups and misconceptions about exercise exacerbating the disease.The study also highlighted the need for better communication between healthcare providers and patients regarding the benefits of PA and safe incorporation into lifestyles.Moreover,physical inactivity may also contribute to disability in IBD patients,having a great impact on employment status.Of note is the fact that IBD also comes with an important psychological burden with relevant evidence suggesting that regular PA can improve mood,reduce anxiety,and enhance mental health.The“BE-FIT-IBD”study advocated for the integration of PA into IBD management,emphasizing the bidirectional link between PA and IBD.Regular exercise can influence the course of IBD,potentiall

关键词： Inflammatory bowel disease Physical activity Disability Psychological burden Body composition Quality of life

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Repeatability,interocular correlation and agreement of optic nerve head vessel density in healthy eyes:a sweptsource optical coherence tomographic angiography study

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 896-903页

作者： Dan-Qi Fang Da-Wei Yang Xiao-Ting Mai carol Y Cheung Hao-Yu Chen Joint Shantou International Eye Center Shantou University&the Chinese University of Hong KongShantou 515041Guangdong ProvinceChina Department of Ophthalmology and Visual Sciences Chinese University of Hong KongHong Kong 999077China

AIM:To assess the repeatability,interocular correlation,and agreement of quantitative swept-source optical coherence tomography angiography(OCTA)optic nerve head(ONH)parameters in healthy subjects.METHODS:Thir ty-three healthy subjects were enrolled.The ONH of both eyes were imaged four times by a swept-source-OCTA using a 3 mm×3 mm scanning protocol.Images of the radial peripapillary capillary were analyzed by a customized Matlab program,and the vessel density,fractal dimension,and vessel diameter index were measured.The repeatability of the four scans was determined by the intraclass correlation coefficient(ICC).The most well-centered optic disc from the four repeated scans was then selected for the interocular correlation and agreement analysis using the Pearson correlation coefficient,ICC and Bland-Altman plots.RESULTS:All swept-source-OCTA ONH parameters exhibited certain repeatability,with ICC>0.760 and coefficient of variation(CoV)≤7.301%.The obvious interocular correlation was observed for papillary vessel density(ICC=0.857),vessel diameter index(ICC=0.857)and fractal dimension(ICC=0.906),while circumpapillary vessel density exhibited moderate interocular correlation(ICC=0.687).Bland-Altman plots revealed an agreement range of-5.26%to 6.21%for circumpapillary vessel density.CONCLUSION:OCTA ONH parameters demonstrate good repeatability in healthy subjects.The interocular correlations of papillary vessel density,fractal dimension and vessel diameter index are high,but the correlation for circumpapillary vessel density is moderate.

关键词： interocular correlation repeatability optic nerve head optical coherence tomography angiography vessel density

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Market Risk Analysis, Quantitative Methods in Finance 1

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丛书名： Wiley Finance Series

2008年

作者： Alexander carol.

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African Ceremonies=非洲意识

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2002年

作者： Beckwith carol

Title translated: 非洲仪式400 p. : col. ill. ; 36 cm. + 1 CD-ROM.

ISBN: (纸本)0810934841

Title translated: 非洲仪式400 p. : col. ill. ; 36 cm. + 1 CD-ROM.

关键词： Rites and ceremonies Africa. Ritual Africa. Initiation rites Africa.

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Fundamentals of nursing : the art and science of nursing care

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2005年

作者： Taylor carol CSFN.

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女性商学院院长增多缩小性别差距

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商业周刊（中文版） 2024年第5期 14-15页

作者： carol Hymowitz 汪泽(译) 不详

在美国商学院中,担任领导职务的女性和男性之间的差距一直在缩小,特别是越来越多的女性被提拔到有望担任院长的后备职位上。据美国精英商学院协会(Association to Advance Collegiate Schools of Business,简筒称AACSB)的一项研究,2023-... 详细信息

在美国商学院中,担任领导职务的女性和男性之间的差距一直在缩小,特别是越来越多的女性被提拔到有望担任院长的后备职位上。据美国精英商学院协会(Association to Advance Collegiate Schools of Business,简筒称AACSB)的一项研究,2023-2024年,美国368所商学院的女院长占总数的30%。这比2007-08年的17%有所提高。

关键词：领导职务 AACSB 商学院性别差距

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改变生活的一体化多功能遥控器

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微型计算机 2006年第32期26卷 80-81页

作者： carol 无（图）不详《本刊编辑部》

家里的摇控器越来越多，有时候真是觉得它们不仅仅是控制家里的电器而是控制我们的生活！能让这一切变得简单些么，这可不是痴人说梦，是时候让这些方头方脑的家伙浓缩集成在一起了。

关键词：生活遥控器多功能一体化摇控器控制

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Mastering COBOL /

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1998年

作者： Baroudi carol.

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Market models

Market models

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2001年

作者： Alexander carol.

ISBN: (纸本)9780471899754

Market Models provides an authoritative and up-to-date treatment of the use of market data to develop models for financial analysis. Written by a leading figure in the field of financial data analysis, this book is the first of its kind to address the vital techniques required for model selection and development. Model developers are faced with many decisions, about the pricing, the data, the statistical methodology and the calibration and testing of the model prior to implementation. It is important to make the right choices and carol Alexander's clear exposition provides valuable insights at every stage. In each of the 13 Chapters, Market Models presents real world illustrations to motivate theoretical developments. The accompanying CD contains spreadsheets with data and programs; this enables you to implement and adapt many of the examples. The pricing of options using normal mixture density functions to model returns; the use of Monte Carlo simulation to calculate the VaR of an options portfolio; modifying the covariance VaR to allow for fat-tailed P&L distributions; the calculation of implied, EWMA and 'historic' volatilities; GARCH volatility term structure forecasting; principal components analysis; and many more are all included. carol Alexander brings many new insights to the pricing and hedging of options with her understanding of volatility and correlation, and the uncertainty which surrounds these key determinants of option portfolio risk. Modelling the market risk of portfolios is covered where the main focus is on a linear algebraic approach; the covariance matrix and principal component analysis are developed as key tools for the analysis of financial systems. The traditional time series econometric approach is also explained with coverage ranging from the application cointegration to long-short equity hedge funds, to high-frequency data prediction using neural networks and nearest neighbour algorithms. Throughout this text the emphasis is on understanding concepts and implementing solutions. It ha

关键词： Stock price forecasting

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Associations between meeting 24-hour movement guidelines and academic achievement in Australian primary school-aged children

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Journal of Sport and Health Science 2022年第4期11卷 521-529页

作者： Amanda Watson Dorothea Dumuid carol Maher Tim Olds Alliance for Research in Exercise Nutrition and Activity(ARENA)Allied Health and Human PerformanceUniversity of South AustraliaAdelaideSA5001Australia

Background:Few studies have investigated associations between academic achievement and meeting recommendations from the 24-hour(24-h)movement guidelines.The specific guidelines associated with the most benefit academic achievement are unknown.Utilizing both self-report and objective movement data,this study examined associations between academic achievement and meeting individual recommendations and combinations of recommendations from the 24-h movement guidelines(sleep,physical activity,and screen time).Methods:Data from CheckPoint,a cross-sectional study nested between Waves 6 and 7 of the Longitudinal Study of Australian Children,were used.Movement behaviors were measured using 24-h wrist-worn accelerometry(GENEActiv(Activinsights,Kimbolton,UK))and were selfreported by children using the Multimedia Activity Recall for Children and Adolescents.Academic achievement was measured using a nationally administered standardized test in literacy and numeracy.Analysis of covariance,with t tests with sequential Bonferroni adjustments,was used to compare academic achievement with all possible combinations of meeting recommendations,adjusting for demographic confounders.Two models were considered:guideline compliance assessed by self-report(n=1270,mean age=11.99 years,52%males)and by accelerometry(for moderate-to-vigorous intensity physical activity(MVPA)and sleep))and self-report(screen time)in combination(n=927,mean age=11.97 years,52%males).Results:Literacy achievement significantly differed based on self-report(F_((7,1258))=3.08,p=0.003)and accelerometer derived(F_((7,915))=2.40,p=0.02)guideline compliance.Numeracy achievement significantly differed based on self-report(F_((7,1258))=2.92,p=0.005)but not accelerometer derived guideline compliance(F_((7,915))=0.80,p=0.58).When assessed by self-report,children who met all guidelines(t_((334))=-4.05,p=0.0001)or met the screen time and sleep guidelines in combination(t_((125))=-5.02,p<0.001)had superior literacy achievement.Meeting the self-report MVPA guideline in any comb

关键词： Academic achievement Physical activity Sedentary behavior Sleep

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