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Determinants of High Blood Pressure and Quality of Management in Three Regions of Benin

Open Journal of Epidemiology 2018年第1期8卷 14-28页

作者： Mohamed Lamine Dramé Corine Houehanou Paulin Sogbohossou René Paré Armand Ekambi carmelle mizéhoun-adissoda Dismand Houinato Karel Gyselinck Michael Marx Maria Rosáttrio Oliveira Martins Paulo Ferrinho GHTM Instituto de Higiene e Medicina Tropical Universidade Nova de Lisboa Lisbon Portugal Faculty of Health Sciences Laboratory of epidemiology of Chronic and Neurological Diseases (LEMACEN) Abomey-Calavi University Cotonou Benin Belgium Technical Cooperation—BTC Cotonou Benin Heidelberg University Heidelberg Germany

Objective: The aim of this work was to determine the prevalence, associated factors and quality of high blood pressure (HBP) management in three regions of Benin in 2015. Methodology: This was a cross-sectional study, with two components. The first component included adults aged from 18 to 69 years, selected using a three-stage random sampling within the households. Data were collected thanks to the French version of the WHO STEPS instrument. Anthropometric data, including blood pressure, capillary fasting glucose and total cholesterol were measured according to standard procedures. The second component included Public Health Centers (PHC) selected by a random stratified multi-stage sampling. Data were collected on the structures and the processes of HBP management using the standardized tool for assessing the capacities of management of non-communicable diseases in peripheral health centers provided by the World Health Organization. Results: A total of 4816 participants were included in the first component. The mean age was 35.8 ± 12.7 years. The weighted prevalence of HBP was 27.9% (95% Confidence Interval (CI) [25.6 - 30.2]). It was higher in the 60 - 69 years compared to the lower age groups (Adjusted Odd-ratio (ORa) = 5;95% CI [3.9 - 6.5)]). HBP was positively associated with urban residence (ORa = 1.26;95% CI [1.24 - 1.28]), obesity (ORa = 1.46;95% CI [1.43 - 1.50]), hyperglycemia (ORa = 1.13;95% CI [1.10 - 1.15)]) and hypercholesterolemia (ORa = 1.64;95% CI [1.59 - 1.70)]). A total of 27 PHC were included in the second component. Taking blood pressure and other anthropometric measurements was not routine in PHC. Several essential medicines were not available in the PHC. A low level of community involvement in the management of HBP was noted. Conclusion: This study confirms the high prevalence of HBP and shows inadequacies in its management in the targeted PHC. More appropriate prevention and control measures for HBP should be implemented.

关键词： High Blood Pressure Determinants Management Benin

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Prevalence and Factors Associated with Overweight and Obesity among Adolescents in Schools in Benin in 2016

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Open Journal of Epidemiology 2019年第3期9卷 213-242页

作者： Olga Agbohoui Houinato Alphonse Kpozehouen Benjamin hounkpatin Kévin Yann Gbédji Hélène Robin carmelle mizéhoun-adissoda Fernand Guédou Dismand Stéphan Houinato René Xavier Perrin Epidemiologic Laboratory for Chronic and Neurological Diseases (LEMACEN) Faculty of Health Sciences University of Abomey Calavi Cotonou Benin Regional Institut of Public Healt. (IRSP) University of Abomey Calavi Cotonou Benin Centre Hospitalier Universitaire de la Mère et de l’Enfant Lagune (CHU MEL) Faculty of Health Sciences University of Abomey Calavi Cotonou Benin Health Center of Sexually Transmitted Infections (DIST) Health Center of Cotonou1 Cotonou Bénin

Introduction Overweight and obesity are considered to be global public health concerns. The objective was to estimate the prevalence of overweight and obesity and the associated factors. Methods This was a cross-sectional study conducted in 2016 and involving 3968 adolescents of 10 to 19 years from 40 secondary schools in Benin. Participants were selected using a 2-level random sampling technique. Data were collected through a self-administered questionnaire and were analyzed using Epi Info and Stata softwares. Associated factors were investigated by a logistic regression. Results Mean age was 16.54 ± 0.04 years and sex ratio was 1.16. The prevalence of overweight was 8.1% and that of obesity was 1.6%. Associated risk factors were female gender, sedentary lifestyle, consumption of sugary and carbonated beverages. Consumption of fruits and vegetables, regular physical activity, age over than 15 years were protective factors. Conclusion Overweight and obesity among school adolescents are increasing in Benin. The establishment of a school nutrition program and the promotion of regular physical activity should contribute to reducing their prevalence.

关键词： Prevalence Overweight Obesity Adolescent School Environment

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Diabetes and Its Treatment Quality in Benin (West Africa): Analysis of Data from the STEPS Survey 2015

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Open Journal of Epidemiology 2018年第4期8卷 242-258页

作者： Mohamed Lamine Dramé carmelle mizéhoun-adissoda Salimanou Amidou Paulin Sogbohossou René Paré Armand Ekambi Corine Houehanou Dismand Houinato Karel Gyselinck Michael Marx Maria Rosàrio Oliveira Martins Paulo Ferrinho Instituto de Higiene e Medicina Tropical Universidade Nova de Lisboa Lisbon Portugal Laboratory of Non-Communicable and Neurologic Diseases Epidemiology Faculty of Health Science University of Abomey-Calavi Cotonou Benin Belgium Technical Cooperation—BTC Cotonou Benin University of Heidelberg Heidelberg Germany

Aims: Diabetes is a major public health problem in low and middle-income countries. This study 1) estimated prevalence and factors associated with hyperglycemia in Benin, and 2) assessed the treatment quality of diabetes. Methodology: A cross-sectional research was conducted with two components. The First component has included 4954 subjects aged (18 - 69) randomly selected in Mono/Couffo and Donga regions. Data were collected according to WHO’s STEPS approach. Capillary blood glucose was measured using the automat Cardiocheck®PA. The Second component considered Public Health Centers (PHCs) within the study regions. Health system established for diabetes control, healthcare practices and the level of involvement of the Public Healthcare Providers and community actors in the management of diabetes have been explored. Findings: A total of 4775 subjects participated in the first component with a predominance of women (56.8%), rural residence and aged (Conclusion: Diabetes prevalence goes increasingly in Benin when its management is inadequate in PHCs. Prevention and control actions should be strengthened.

关键词： Diabetes Determinants Treatment Benin

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Factors Associated with Hypovitaminosis D in People Living with HIV/AIDS (PLWHA) Followed up in Porto-Novo in 2019

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Food and Nutrition Sciences 2021年第11期12卷 1020-1027页

作者： Alassani Adébayo Gninkoun Comlan Jules mizèhoun-adissoda carmelle Dovonou C. Albert Attinsounon Cossi Wanvoégbè Armand Medicine and Medical Specialties Faculty of Medicine University of Parakou Parakou Benin Medicine and Medical Specialties Faculty of Medicine University of Abomey-Calavi Abomey-Calavi Benin

Background: Vitamin D deficiency is very common among PLWHA compared to the general population and is promoted by several factors. Aim: To identify the factors associated with hypovitaminosis D in people living with HIV/AIDS (PLWHA) followed up in Porto-Novo in 2019. Methods: This was a cross-sectional, descriptive and analytical study. PLWHA who were monitored on an outpatient basis and who gave their consent were included in this work. Subjects unable to answer questions or under ongoing vitamin D supplementation or suffering from chronic liver diseases were not included. Hypovitaminosis D was defined by a blood level of 25 hydroxy-vitamin D less than 30 ng/mL. Results: A total of 270 PLWHA were included in the study. The mean age of the patients was 39.51 ± 6.85 years with a female predominance (73.3%). The frequency of hypovitaminosis D was 56%. Hypertension, low protein intake, anemia and low glomerular filtration rate were associated with vitamin D deficiency. Conclusion: Vitamin D deficiency is common among PLWHA, which justifies routine screening, especially among those at risk.

关键词： Hypovitaminosis D PLWHA Malnutrition Denutrition Porto-Novo

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Geochemical and Petrological Insights into the Neoproterozoic Moumba Metabasites: Implications for Crustal Processes in the West Congo Belt (Republic of Congo)

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Journal of Geoscience and Environment Protection 2024年第2期12卷 1-29页

作者： Ulrich Verne Matiaba-Bazika Nelson Lekeba Makamba Vicky Tendresse Télange Bouénitéla Nicy carmelle Bazebizonza Tchiguina Timothée Miyouna Florent Boudzoumou Laboratory of Geosciences Faculty of Sciences and Technics Marien NGOUABI University Brazzaville Republic of Congo National Institute for Research in Exact and Natural Sciences (IRSEN) Brazzaville Republic of Congo Geographid Research and Cartographic Production Center (CERGEC) Brazzaville Republic of Congo

The West Congo Belt contains in its rocks of Neoproterozoic age from Nemba complex outcropping in the Moumba River. This West Congo belt is made up of a crustal segment of the Arcuaï-West Congo orogen which extends from southwest Gabon to the northeast of Angola. This study aims to constrain the geochemical signature Nemba complex of West Congo belt from the petrograhic and geochemical study on the whole rock. The petrographic data from this study show the Moumba metabasites are made up of amphibolites, metagabbros, epidotites and greenschists interstratified in the Eburnean metasediments and affected by mesozonal to epizonal metamorphism characterized by the retromorphosis of intermediate amphibolite facies minerals into greenschist facies. Whole-rock geochemical data indicate that these metabasites are continental flood basalts (CFB) of basic nature and transitional affinity emplaced in intraplate context. These continental flood basalts are generated from magma originating from a significantly enriched shallow mantle plume and this magma then contaminated by the continental crust during their ascent. The reconstruction of tectonic signature suggests that West Congo belt would result from closure of an ocean basin with subduction phenomena. This collision would be marked by the establishment of ophiolite complex. We show that this model is incompatible with the CFB nature of metabasites and the orogenic evolution of Neoproterozoic. It does not seem that we can evoke a genetic link with a subduction of oceanic crust, because the paleogeography of Neoproterozoic (Rodinia) is marked by intracontinental rifts linked to opening of Rodinia. We therefore suggest the non-existence of ophiolitic complex in western Congo belt and reject the collisional model published by certain authors. We confirm the currently available intracontinental orogen model.

关键词： Mayombe Metabasites Moumba Mantle Plume Continental Rifting Basalts Flood Continental

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Prevalence and Predictors of Double Burden of Malnutrition within Households in Africa: A Systematic Review

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Food and Nutrition Sciences 2023年第10期14卷 908-927页

作者： Reynald Santos Charles Sossa Jerome Colette Azandjeme carmelle mizehoun-adissoda Clémence Metonnou Department of Health Promotion Regional Institute of Public Health (IRSP) of Ouidah Ouidah Benin School of Nutrition and Dietetics Faculty of Health Sciences (FSS) of Cotonou Cotonou Benin

In recent years, there has been growing interest in the emergence of double burden of malnutrition (DBM) in Africa. In this study, we reviewed the literature on double burden of malnutrition in households, reviewing previous studies investigating the prevalence of DBM in Africa and the factors associated with it. To identify relevant studies, we consulted the PubMed and Cochrane electronic databases, using specific search terms. A total of seventeen articles met the eligibility criteria. These articles were published between 2012 and 2022, and their data were collected between 2000 and 2019. Twelve of these studies used secondary data, including demographic and health surveys. The age of children and adults varied from study to study. All studies used Body Mass Index as a nutritional indicator for adults. For children, the height-for-age Z-score was most commonly used, while weight-for-age, weight-for-height and Body Mass Index-for-age were less commonly used. The national prevalence of double nutritional burden in households ranged from 1.71% to 38.7%, depending on the country and the year. However, direct comparisons between studies were limited due to differences in combinations of undernutrition, overweight or obesity. Among the factors associated with double nutritional burden within households, the most frequently cited in the selected articles were urban/rural residence, income or socioeconomic status, age of child and mother, household size and mother’s level of education. However, no study assessed physical activity, and very few examined the diet of household members. It is essential to take these different parameters into account when designing and implementing interventions to prevent the DBM in Africa. Community and societal factors will also need to be studied and taken into account in these interventions.

关键词： Double Burden of Malnutrition Household Prevalence Associated Factors Africa

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Factors Associated with Hypovitaminosis D in People Living with HIV/AIDS (PLWHA)Followed up in Porto-Novo in 2019

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Food and Nutrition Sciences 2021年第11期

作者： Alassani Adébayo Gninkoun Comlan Jules mizèhoun-adissoda carmelle Dovonou C. Albert Attinsounon Cossi WanvoégbèArmand

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Etiologies of Bone Metastases at the Rheumatology Department (UTH) of Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2020年第1期10卷 1-7页

作者： Mariam Gbané Jean Claude Soglo Mohamed Diomandé Guy Léopold Kengni Baly Ouattara Jean Mermoz Djaha Kouassi You Nina carmelle Kpami Yaya Coulibaly Edmond Eti Rheumatology Department University Teaching Hospital (UTH) of Cocody Abidjan C&#244 te d'Ivoire

Objectives: The aim of this study was to describe the diagnostic and etiological aspects of bone metastases in the Rheumatology Department of Cocody’s University Teaching Hospital (UTH). Methodology: This was a descriptive, 11-year retrospective study (January 1, 2006 to December 31, 2016) of inpatient records of bone metastases. The diagnosis was made on clinical (bone signs), radiological (osteolysis, bone condensation) and sometimes histological basis. Result: Eighty out of 6, 1111 inpatients suffered from bone metastasis with a hospital frequency of 1.30%. The average age was 60.74 years (range 26 to 81 years). Men were predominant (53 men for 27 women) with a sex ratio of 1.96. The main complaints were pain (97.6%). chronic (90%), severe (73.8%), inflammatory (93.8%). There was sometimes a neurological complication: a motor deficit (21.3%), sensitive (13.8%). These symptoms were associated with fever (56.3%) and altered general state (85%). Bone metastases have been revealing in the vast majority of cases (93.75%);the primary cancer was known only in 5 patients (prostate = 2, breast = 2 and cervix = 1). Bone condensation (61.3%), osteolysis (50%) and mixed lesions (7.5%) where the main radiological lesions observed. The primary tumors were: prostatic (50%), pulmonary (18.8%), mammary (11.3%), uterine (5%), renal (2.5%), hepatic (2.5%), bladder (1.3%) and adrenal (1.3%). Conclusion: Bone metastases affect mostly the elderly;inflammatory spinal pain is the main symptom. Bone condensation is the most common radiologic lesion. The prostate, breast and lungs are the main primary tumors.

关键词： Bone Metastases Bone Condensation Prostate Cancer Africa

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Resistance to Abiotic Stress and Effectiveness of Native Rhizobia on Bambara Groundnut [Vigna subterranea (L.) Verdc.] in Benin

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Open Journal of Soil Science 2022年第6期12卷 193-215页

作者： Mahougnon carmelle Charlotte Zoundji Agassin Martinien Arcadius Ahoglé Tobi Moriaque Akplo Sèmèvo Oslo Gangnon Diorel Montéiro Yves Zanvo Félix Kouelo Alladassi Pascal houngnandan Laboratoire des Sciences Végétales Horticoles et Forestières Université Nationale d’Agriculture Kétou Benin Ecole de Gestion et de Production Végétale et Semencière Université Nationale d’Agriculture Kétou Benin Laboratoire de Microbiologie des Sols et d’Ecologie Microbienne Faculté des Sciences Agronomiques Université d’Abomey-Calavi Cotonou Benin Department of Spatial and Environmental Planning Kenyatta University Nairobi Kenya Faculté d’Agronomie Université de Parakou Parakou Benin

Bambara groundnut [Vigna subterranea (L.) Verdc.], as a legume, can establish relationships with nitrogen-fixing bacteria such as Rhizobium. However, Rhizobium efficacy is not always optimal due to the lack or poor efficient strains in the soil. This study aimed to evaluate symbiotic efficiency of endogenous Rhizobia nodulating Bambara groundnut and their resistance to abiotic conditions. Root nodules were randomly sampled from three agroecological zones across the country, surface sterilized, ground and paste plated on YEMA media. After 24 hours, the bacterial colonies were purified. The pure cultures were further characterized using morphological and biochemical methods and their resistance to antibiotics and heavy metals was evaluated. Lastly, the symbiotic efficiency of the isolates was assessed through a greenhouse experiment. A total of eighty-five presumptive strains were isolated from Bambara groundnut roots nodules obtained from the farms. The physiological characterization of the isolated showed a decrease in isolates growth when NaCl concentration was more than 7%. In addition, 47% of the isolates were tolerant to a temperature of 40°C. Most of the isolates were highly resistant to Erythromycin in all its concentration levels and to Kanamycin, Spectinomycin, Neomycin and Ampicillin at 10 μg⋅mL−1. Most of them showed resistance to Cu and Zn at 10 μg⋅mL−1. Results of the effectiveness test on two Bambara groundnut varieties yielded dry shoot matter varying from 3.33 g⋅plant−1 to 7.21 g⋅plant−1 for variety 1 and from 4.38 g⋅plant−1 to 8.38 g⋅plant−1 on variety 2. N uptake ranged between 0.09 g⋅plant−1 and 0.29 g⋅plant−1 for variety 1 and between 0.12 and 0.29 g⋅plant−1 for variety 2. The isolates yielding higher shoot dry weight and N uptake were LMSEM312, LM

关键词： Indigenous Rhizobia Nitrogen Fixation Biodiversity Bambara Groundnut West Africa

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Mesenteric infarction due to iatrogenic polycythemia

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World Journal of Emergency Medicine 2013年第3期4卷 232-234页

作者： Katrina Skoog Marie carmelle-Elie Kevin Ferguson University of Florida School of Medicine GainesvilleFLUSA

BACKGROUND:Polycythemia vera is defined as a chronic myeloproliferative disorder characterized by increased red blood cell *** have been no reports on mesenteric thrombosis resulting from iatrogenic ***:We present a patient with a history of non-small cell lung cancer undergoing maintenance oral chemotherapy on tarceva and adjunctive use of *** patient presented to our emergency department with an acute abdomen and was found to have ischemic bowel from unmonitored procrit,which lead to hyperviscosity of blood and mesenteric ***:The patient remained intubated with ventilator *** refused a *** continued on feeding through the J port of the nasojejunal *** white cell count,and hematocrit and creatinine levels remained *** use and chemotherapy were not *** was transferred to a subacute nursing facility for further ***:Procrit and other erythropoiesis stimulating drugs can cause significant morbidity and mortality with an increased risk of cardiovascular events,gastrointestinal bleeding,thromboembolism and *** case report suggests that without closely monitoring hematocrit levels,epoetin may also be associated with an increased risk of mesenteric infarction.

关键词： Mesenteric infarction latrogenic polycythemia

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