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Journal of Intensive Medicine 2022年第2期2卷 103-109页

作者： Diego Gil carlos tiscar Maria Gómez Javier Felices Luis Gajate Patricia Fernandez David Pestaña Tommaso Bardi Department of Anaesthesiology and Critical Care Ramón y Cajal Hospital28034 MadridSpain Department of Psychology Ramón y Cajal Hospital28034 MadridSpain

Background:There are insufficient data regarding the impact of acute respiratory distress syndrome related to coronavirus disease 2019(C-ARDS)–caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)–on health-related quality of life(HRQoL)and the occurrence of stress-related disorders in coronavirus disease 2019(COVID-19)intensive care unit(ICU)*** aim of this study is to assess HRQoL and the occurrence of stress-related disorders(acute stress disorder[ASD]and post-traumatic stress disorder[PTSD])in C-ARDS ICU survivors at 1 and 6 months following hospital ***:This prospective observational study included 90 patients treated for C-ARDS between March and May 2020 in the ICU and discharged alive from the *** patients included in the study were contacted by telephone 1 month and 6 months post-hospital discharge to assess the presence of symptoms of stress-related disorders and HRQoL using the 8-item Treatment Outcome Post-traumatic Stress Disorder scale(TOP-8)and 36-item Short Form survey(SF-36).We performed univariate analyses to evaluate differences between patients who developed stress and those who did *** also compared SF-36 scores in our sample with data from the general Spanish population and from cohorts of non–C-ARDS and severe acute respiratory syndrome coronavirus-1(SARS-CoV-1)***:There are 24.1%of patients showed symptoms of ASD;in 13.5%of cases the symptoms persisted 6 months *** factors for the development of symptoms of ASD and PTSD are younger age,female sex,obesity,a previously diagnosed psychiatric disease and disease severity at ICU admission(P<0.05).HRQoL was greatly affected by C-ARDS;however,there was improvement on all scales of the SF-36 at the 6-month follow-up(P<0.05).The mean SF-36 score of our sample was higher than those previously reported in non–C-ARDS survivors(P<0.05)for physical functioning(78.0 vs.52.0),role functioning/physical(51.0 vs.31.0),bodily pain(76.1 vs.57

关键词： COVID-19 Post-intensive care syndrome Respiratory distress syndrome,Adult Health-related quality of life Post-traumatic stress disorder

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