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Parkinson's disease, heart disease and propolis consumption

Journal of Integrative Medicine 2021年第5期19卷 467-468页

作者： Fulvio a.scorza Antonio-Carlos G.de Almeida carla a.scorza Ana C.Fiorini Josef Finsterer Disciplina de Neurociência Escola Paulista de MedicinaUniversidade Federal de Sao Paulo(EPM/UNIFESP)Sao PauloSP 04021-001Brazil Centro de Neurociências e Saúde da Mulher Escola Paulista de MedicinaUniversidade Federal de Sao Paulo(EPM/UNIFESP)Sao PauloSP04021-001Brazil Departamento de Engenharia de Biossistemas Universidade Federal de Sao Joao del-Rei(UFSJ)Sao Joao del-ReiMG36307-352Brazil Departamento de Fonoaudiologia Escola Paulista de MedicinaUniversidade Federal de Sao Paulo(EPM/UNIFESP)Sao PauloSP04021-001Brazil Brazil-Programa de Estudos Pós-Graduado em Fonoaudiologia Pontifícia Universidade Católica de Sao Paulo(PUC-SP)Sao PauloSP04021-001Brazil Klinikum Landstrasse Messerli InstituteVienna 1210Austria

It is reported that neurodegeneration is a process that is implicated in both neuropharmacological disorders and brain aging [1].Research has shown that natural products have a wide range of pharmacological and biolog... 详细信息

关键词： Parkinson’s disease heart disease and propolis consumption

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Physical activity in sudden unexpected death in epilepsy: much more than a simple sport

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Neuroscience Bulletin 2008年第6期24卷 374-380页

作者： Ricardo M.ARIDA carla a.scorza Beny SCHMIDT Marlyde ALBUQUERQUE Esper A.CAVALHEIRO Fulvio a.scorza 圣保罗联邦大学生理学系圣保罗联邦大学实验神经生物学实验室圣保罗联邦大学病理学系

Sudden unexpected death in epilepsy （SUDEP） is the most important direct epilepsy-related cause of death. Additionally, potential pathomechanisms for SUDEP is unknown, but it is very probable that cardiac arrhythmia during and between seizures, electrolyte disturbances, arrhythmogenic drugs or transmission of epileptic activity via the autonomic nervous system to the heart may play a potential role. Quite interestingly, clinical and experimental data have shown that physical activity can decrease seizure frequency, as well as lead to improved cardiovascular health in patients with epilepsy. Based on these facts, the purpose of this article is to review the body of literature of the possible contribution of physical exercise to the SUDEP prevention in a comprehensive manner.

关键词： sudden unexpected death in epilepsy physical activity epilepsy heart seizure

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Mitochondrial tRNA Glutamic Acid Variant 14709T〉C Manifesting as Myoclonic Epilepsy with Ragged Red Fibers

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Chinese Medical Journal 2018年第20期131卷 2518-2519页

作者： Josef Finsterer Fulvio a.scorza Ana C Fiorini carla a.scorza Antonio Carlos de Almeida Department of Neurology City Hospital Rudolfstiftung Vienna Austria Department of Neuroscience University of Sao Paolo Sao Paolo Brazil Department of Audiology University of Sao Paolo Sao Paolo Brazil Department of Biosystems Engineering Laboratory of Experimental and Computational Neuroscience Sao Paolo Brazi

We read with interest the case report by Ban et al. about a 17-year-old male with myoclonic epilepsy with ragged red fibers （MERRF） syndrome being attributed to the mitochondrial tRNA glutamic acid （tRNA [Glu]） variant mitochondrial 14709T〉C. The authors claimed that the variant occurred sporadically and has not been reported in association with a MERRF phenotype so far. We have the following comments and concerns.

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Repurposing the antioxidant and anti-inflammatory agent N-acetyl cysteine for treating COVID-19

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World Journal of Virology 2022年第1期11卷 82-84页

作者： Josef Finsterer Fulvio a.scorza carla a.scorza Ana C Fiorini Department of Neurology University of Sao PaoloSao Paolo 01000-000Brazil

Although several considerations have been raised suggesting a beneficial effect of N-acetyl cysteine(NAC)for the treatment of severe acute respiratory syndrome coronavirus 2 infection,there is currently no clinical evidence that NAC truly prevents coronavirus disease 2019(COVID-19),reduces the severity of the disease,or improves the *** designed clinical trials are warranted to prove or disprove a therapeutic effect of NAC for COVID-19 patients.

关键词： N-acetyl cysteine SARS-CoV-2 COVID-19 Reactive oxygen species Cytokines

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