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基于中子/瞬发γ射线联合测量的中子剂量监测模拟研究

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同位素 2024年第4期37卷 372-378页

作者：程璨贾文宝顾加雨邢立腾胡尊浩马靖武夏勋荣江苏省计量科学研究院(江苏省能源计量数据中心) 南京210023 南京航空航天大学南京211106 南京中医药大学附属医院(江苏省中医院) 南京210019

辐射场下的中子周围剂量当量率监测具有重要意义,其可以反应核设施运行状况以及辐射防护信息。目前常用的监测仪器为基于单探测器、单慢化体的A-B型剂量当量率仪,其响应曲线与“中子注量-周围剂量当量转换系数”有较大的差异,导致测量... 详细信息

辐射场下的中子周围剂量当量率监测具有重要意义,其可以反应核设施运行状况以及辐射防护信息。目前常用的监测仪器为基于单探测器、单慢化体的A-B型剂量当量率仪,其响应曲线与“中子注量-周围剂量当量转换系数”有较大的差异,导致测量结果误差较大。为提升中子剂量仪测量结果的准确性,对基于中子和瞬发γ射线联合监测中子剂量率开展研究。利用铅块、含硼聚乙烯、有机玻璃和氯化钠组合而成的转换材料,通过蒙特卡罗模拟计算B、H、Cl、Pb、C和O元素对不同能量中子的响应,利用响应曲线结合LB6411型剂量仪的响应曲线进行线性拟合,得到与“中子注量-周围剂量当量转换系数”更为接近的响应曲线。通过差分进化算法计算得到线性拟合系数,结果显示,新的响应曲线在1×10^(-8)~16 MeV能量区间内与h_(φ)响应曲线更贴近,二者的相对偏差在50%之内。联合测量中子与瞬发γ射线对中子周围剂量当量率进行监测可行,为中子剂量仪校准和研发提供了新的方向和支持。

关键词：中子周围剂量当量瞬发γ射线响应曲线差分进化算法

Characteristics of pathogens detected in adults with hematological malignancies and nosocomial infections in the tropics

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Chinese Medical Journal 2020年第14期133卷 1735-1737页

作者： Li-Ping Dou cheng Hou Ting Yang Long-can cheng Jian Bo Department of Hematology Hainan Branch of Chinese People’s Liberation Army General HospitalSanyaHainan 572013China Department of Hematology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China

To the Editor:Human pathogens have evolved over a long time to become mesophiles to adapt to the typical 37°C temperature of the human *** and yeast-like fungi also grow very well at this temperature,while the optimal temperature for the growth of filamentous fungi is 25 to 28℃.Hainan Island in China has a tropical oceanic monsoon climate with indistinct *** mean temperature at this place for many years has been 24.4℃,and the annual temperature variation is small;the precipitation is approximately 1718.6 mm,and the relative humidity is 82%.These unique weather characteristics provide a favorable growth environment for *** with hematologic malignancies have poor immunity and are susceptible to *** results in high nosocomial infection rates in patients with hematologic malignancies and frequent antibiotic *** surveys of different regions and hospitals can provide more guidance for clinical drug administration by hematologists in treating infections in patients with hematologic malignancies.

关键词： pathogens infections immunity

Multi-functional metasurface:ultra-wideband/multi-band absorption switching by adjusting guided-mode resonance and local surface plasmon resonance effects

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Communications in Theoretical Physics 2024年第6期76卷 174-184页

作者： Wenxin Li Shubo cheng Huafeng Zhang Zao Yi Bin Tang can Ma Pinghui Wu Qingdong Zeng Rizwan Raza School of Physics and Optoelectronic Engineering Yangtze UniversityJingzhouHubei 434023China Joint Laboratory for Extreme Conditions Matter Properties Southwest University of Science and TechnologyMianyang 621010China School of Chemistry and Chemical Engineering Jishou UniversityJishou 416000China School of Microelectronics and Control Engineering Changzhou UniversityChangzhou 213164China Department of Oncology Sichuan Science City HospitalMianyangSichuan Province 621000China Office of Science and Technology Quanzhou Normal UniversityQuanzhou 362000China School of Physics and Electronic-information Engineering Hubei Engineering UniversityXiaogan 432000China Department of Physics COMSATS Institute of Information Technology 54000 LahorePakistan

This study introduces an innovative dual-tunable absorption film with the capability to switch between ultra-wideband and narrowband *** manipulating the temperature,the film can achieve multi-band absorption within the 30-45 THz range or ultra-wideband absorption spanning 30-130 THz,with an absorption rate exceeding ***,the structural parameters of the absorption film are optimized using the particle swarm optimization(PSO)algorithm to ensure the optimal absorption *** absorption response of the film is primarily attributed to the coupling of guided-mode resonance and local surface plasmon resonance *** film's symmetric structure enables polarization incoherence and allows for tuning through various means such as doping/voltage,temperature and structural *** the case of a multi-band absorption response,the film exhibits good sensitivity to refractive index changes in multiple absorption ***,the absorption spectrum of the film remains effective even at large incidence angles,making it highly promising for applications in fields such as biosensing and infrared stealth.

关键词： PSO optimization ultra-wideband/narrowband absorption switching intelligent absorption film vanadium dioxide

Preoperative albumin-bilirubin score predicts short-term outcomes and long-term prognosis in colorectal cancer patients undergoing radical surgery

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2096-2105页

作者： Yu-Hang Diao Xin-Peng Shu can Tan Li-Juan Wang Yong cheng Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND The albumin-bilirubin(ALBI)score is a serum biochemical indicator of liver function and has been proven to have prognostic value in a variety of *** colorectal cancer(CRC),a high ALBI score tends to be associated with poorer *** To investigate the correlation between the preoperative ALBI score and outcomes in CRC patients who underwent radical *** Patients who underwent radical CRC surgery between January 2011 and January 2020 at a single clinical center were *** ALBI score was calculated by the formula(log10 bilirubin×0.66)+(albumin×-0.085),and the cutoff value for grouping patients *** short-term outcomes,overall survival(OS),and disease-free survival(DFS)were *** A total of 4025 CRC patients who underwent radical surgery were enrolled in this study,and there were 1908 patients in the low ALBI group and 2117 patients in the high ALBI *** regression analysis revealed that age,tumor size,tumor stage,ALBI score,and overall complications were independent risk factors for OS;age,tumor stage,ALBI score,and overall complications were identified as independent risk factors for *** A high preoperative ALBI score is correlated with adverse short-term outcomes,and the ALBI score is an independent risk factor for OS and DFS in patients with CRC undergoing radical surgery.

关键词： Colorectal cancer Albumin-bilirubin score Overall survival Disease-free survival Outcomes

Safety and efficacy of a programmed cell death 1 inhibitor combined with oxaliplatin plus S-1 in patients with Borrmann large type III and IV gastric cancers

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1281-1295页

作者： Zhe-Han Bao can Hu Yan-Qiang Zhang Peng-cheng Yu Yi Wang Zhi-Yuan Xu Huan-Ying Fu Xiang-Dong cheng Department of Interventional Radiology Zhejiang Cancer HospitalHangzhou 310004Zhejiang ProvinceChina Department of Gastric Surgery Zhejiang Cancer HospitalHangzhou 310022Zhejiang ProvinceChina Department of Colonic Surgery Jinhua Central HospitalJinhua 321000Zhejiang ProvinceChina Department of Breast Surgery Lin’an People’s HospitalHangzhou 311300Zhejiang ProvinceChina

BACKGROUND Gastric cancer(GC)is the fifth most common and the fourth most lethal malignant tumour in the *** patients are already in the advanced stage when they are diagnosed,which also leads to poor overall *** effect of posto-perative adjuvant chemotherapy for advanced GC is unsatisfactory with a high rate of distant metastasis and local *** To investigate the safety and efficacy of a programmed cell death 1(PD-1)inhibitor combined with oxaliplatin and S-1(SOX)in the treatment of Borrmann large type III and IV *** A retrospective analysis(IRB-2022-371)was performed on 89 patients with Borrmann large type III and IV GCs who received neoadjuvant therapy(NAT)from January 2020 to December *** to the different neoadjuvant treatment regimens,the patients were divided into the SOX group(61 patients)and the PD-1+SOX(P-SOX)group(28 patients).RESULTS The pathological response(tumor regression grade 0/1)in the P-SOX group was significantly higher than that in the SOX group(42.86%vs 18.03%,P=0.013).The incidence of ypN0 in the P-SOX group was higher than that in the SOX group(39.29%vs 19.67%,P=0.05).The use of PD-1 inhibitors was an independent factor affecting tumor regression ***,the use of PD-1 did not increase postoperative complications or the adverse effects of *** A PD-1 inhibitor combined with SOX could significantly improve the rate of tumour regression during NAT for patients with Borrmann large type III and IV GCs.

关键词： Neoadjuvant therapy Immunotherapy Gastric cancer Borrmann type Tumor regression grade

Instant Effects of Radiofrequency Electromagnetic Wave on Hemoglobin in Single Living Intact Red Blood Cell

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Chinese Chemical Letters 2005年第8期16卷 1121-1124页

作者： cheng can YAO Xiao Kun LI Yao Xiong HUANG College of Pharmacy Jinan University Guangzhou 510630 Institute of Biomedical Engineering Jinan University Guangzhou 510630

The absorption spectrum of the hemoglobin （Hb） in single riving intact red blood cell（RBC）, exposed in 900 MHz radiofrequency electromagnetic wave （RF-EMW）, was non-invasive,in situ, real-time measured by employing a highly sensitive fast multi-channel microspectrophotometer system. Both the absorption intensity and site of intracellular Hb were altered after RBCs were exposed in 900 MHz RF-EMW with power density at 5 mW/cm^2. It was indicated that not only the concentration of Hb in living RBCs was decreased, but the molecular structure of Hb was changed by the RF-EMW action.

关键词： Radiofrequency electromagnetic wave hemoglobin absorption spectrum structure and function.

Optimization of PGNAA set-up for the elements detection in aqueous solution

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Science China(Technological Sciences) 2014年第3期57卷 625-629页

作者： JIA WenBao HEI DaQian cheng can ZHANG HaoJia SHAN Qing College of Materials Science and Engineering Nanjing University of Aeronautics and Astronautics

A prompt gamma neutron activation analysis(PGNAA)set-up was developed for the elements detection in aqueous solution,which includes a 241Am-Be neutron source and a 4-inch BGO *** geometry of set-up is determined by a series of simulations with the MOCA code to improve the efficiency of the elements *** thermal neutron flux and the gamma-ray self-absorption are considered during the optimization *** were performed to validate the set-up using samples including chlorine and mercury,*** result shows that the characteristic peak count has linear relationship with the chlorine and mercury concentration *** minimum detectable concentrations of chlorine and mercury were found as 54 mg/L and 51.4 mg/L,respectively.

关键词： PGNAA 检测效率优化计算水溶液元素设置中子活化分析 BGO探测器

Developer Role Evolution in Open Source Software Ecosystem： An Explanatory Study on GNOME

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Journal of Computer Science & Technology 2017年第2期32卷 396-414页

作者： can cheng Bing Li Zeng-Yang Li Yu-Qi Zhao Feng-Ling Liao International School of Software Wuhan University Wuhan 430072 China State Key Laboratory of Software Engineering Wuhan University Wuhan 430072 China Complex Networks Research Center Wuhan University Wuhan 430072 China

An open source software （OSS） ecosystem refers to an OSS development community composed of many software projects and developers contributing to these projects. The projects and developers co-evolve in an ecosystem. To keep healthy evolution of such OSS ecosystems, there is a need of attracting and retaining developers, particularly project leaders and core developers who have major impact on the project and the whole team. Therefore, it is important to figure out the factors that influence developers＇ chance to evolve into project leaders and core developers. To identify such factors, we conducted a case study on the GNOME ecosystem. First, we collected indicators reflecting developers＇ subjective willingness to contribute to the project and the project environment that they stay in. Second, we calculated such indicators based on the GNOME dataset. Then, we fitted logistic regression models by taking as independent variables the resulting indicators after eliminating the most collinear ones, and taking as a dependent variable the future developer role （the core developer or project leader）. The results showed that part of such indicators （e.g., the total number of projects that a developer joined） of subjective willingness and project environment significantly influenced the developers＇ chance to evolve into core developers and project leaders. With different validation methods, our obtained model performs well on predicting developmental core developers, resulting in stable prediction performance （0.770, F-value）.

关键词： developer role evolution open source software ecosystem project environment subjective willingness

Synthesis of Iron Chlorophyllins and Their Catalytic Performance for Aerobic Oxidation of Cyclohexene

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Chemical Research in Chinese Universities 2013年第3期29卷 526-532页

作者： LIU Xiao-hong LI Yong-jin YANG Wei-jun GUO can-cheng College of Chemistry and Chemical Engineering Hunan University Changsha 410082 P. R. China

A series of iron（III） chlorophyllins was prepared from silkworm excrement crude chlorophyll extract as a raw material. Aerobic oxidation of cyclohexene by using the prepared iron（III） chlorophyllins as biomimetic catalysts was studied under atmospheric pressure in the absence of reducing agent and solvent. The results indicate that chloro- phyll iron porphyrins have better catalytic performance than the industrial-applied iron tetraphenylporphyrin and cobalt tetraphenylporphyrin, and possess a higher selectivity for 2-cyclohexen-1-one. The smaller the polarity of iron（III） chlorophyllin＇s ligand is, the easier the catalytic oxidation of cyclohexene will be. Esterification products of iron（III） chlo- rophyllins can catalyze the oxidation of cyclohexene better than non-esterified iron（III） chlorophyllins, and therefore show a higher conversion of cyclohexene and a higher selectivity for 2-cyclohexen-l-one than the non-esterified ones. Among the six synthesized iron（III） chlorophyllin catalysts, iron（III） methyl-pyropheophorbide-a is the best biomimetic catalyst for the highest conversion of cyclohexene. The influences of catalyst＇s substituent, polarity and ring structure on the catalytic performance were discussed. The catalytic performance of iron（III） chlorophyllins improves with decreasing polarity, increasing conjugated degree of porphyrin＇s ring or enhancing chlorophyllins＇ stability. Possible mechanism of cyclohexene aerobic oxidation catalyzed by iron（III） chlorophyllins was also discussed.

关键词： Chlorophyll Iron chlorophyltin Air Cyclohexene Catalytic oxidation