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Comparison between Non-Gaussian Puff Model and a Model Based on a Time-Dependent Solution of Advection-Diffusion Equation

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Journal of Environmental Protection 2010年第2期1卷 172-178页

作者： Tiziano Tirabassi davidson M. Moreira Marco Tullio Vilhena camila pinto da costa 不详

A comparison between a non-Gaussian puff model and an advanced time-dependent model to simulate the pollutant dispersion in the Planetary Boundary Layer is presented. The puff model is based on a general technique for solving the K-equation, using the truncated Gram-Charlier expansion (type A) of the concentration field and finite set equations for the corresponding moments. The other model (named ADMM: Analytical Dispersion Multilayers Model) is an semi- analytical solution to the time-dependent two-dimensional advection-diffusion equation based on a discretization of the PBL in N sub-layers;in each sub-layers the advection-diffusion equation is solved by the Laplace transform technique, considering an average value for eddy diffusivity and the wind speed. A preliminary performance evaluation is shown in the case of continuous emission from an elevated source in a variable boundary layer. Both models were able to correctly reproduce the concentration field measured and so to be used as operative air pollution models.

关键词： Advection-Diffusion Equation Air Pollution Modeling Analytical Solution Puff Models

Compounds from Stevia rebaudiana Bertoni leaves: An overview of non-conventional extraction methods and challenges

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Food Bioscience 2022年第2期46卷 108-121页

作者： Dj´essica Tatiane Raspe camila da Silva Silvio Cl´audio da costa ograma de P´os-Graduaç˜ao em Ciˆencia de Alimentos Universidade Estadual de Maring´aAv.Colombo579087020-900Maring´aPRBrazil Departamento de Tecnologia Universidade Estadual de Maring´aAv.ˆAngelo Moreira da Fonseca180087506-370UmuaramaPRBrazil Departamento de Bioquímica Universidade Estadual de Maring´aAv.Colombo579087020-900Maring´aPRBrazil

To overcome the inconveniences related to its conventional obtainment of natural sweeteners and active compounds from Stevia rebaudiana Bertoni,methods involving application of technology,such as ultrasound assisted extraction,microwave assisted extraction,extraction under pressurized conditions by means of pressurized liquid extraction,subcritical water extraction and supercritical fluid extraction have been *** this review,these emerging techniques were analyzed and discussed,the process variables and operational strategies,their impacts on the extraction and their comparison against the conventional techniques were *** and the possibility of operational automation,the use of less energy and solvents,in addition to the reduced complexity of the subsequent purification steps,make up viable alternatives suitable for a possible industrial *** processes leverage the concept of green chemistry,but still suffer limitations related to acquisition and maintenance costs,in addition to the effects of the action of some of these technologies remaining unexplored.

关键词： Active compounds Natural sweeteners Steviol glycosides Technology application

Adsorption of yttrium(Y^(3+)) and concentration of rare earth elements from phosphogypsum using chitin and chitin aerogel

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Journal of Rare Earths 2024年第4期42卷 775-782页

作者： Glaydson S.dos Reis Diana pinto Sabrina F.Lütke Eder C.Lima Luis F.O.Silva Irineu A.S.De Brum Guilherme L.Dotto Department of Forest Biomaterials and Technology Biomass Technology Centre Swedish University of Agricultural SciencesUmeaE13Swedn Universidad De La costa Calle 58#55-66080002BarranquillaAtlanticoColombia Research Group on Adsorptive and Catalytic Process Engineering(ENGEPAC) Federal University of Santa MariaAv.Roraima100079705900Santa MariaRSBrazil Institute of Chemistry Federal University of Rio Grande do Sul90040060Porto AlegreBrazil

Chitin powder and chitin-aerogel were prepared from shrimp wastes and used to uptake Y^(3+)from aqueous solutions and concentrate this rare earth element from phosphogypsum(PG).Chitin aerogel displays a specific surface area of 945 m^(2)/g,while chitin powder is 3.6 m^(2)/g,which largely influences its adsorption *** the adsorption in synthetic solutions,the effect of pH on Y^(3+)removal is strong for chitin powder *** contrast,no big pH influence was detected for chitin *** interactions and chelation can highlight the proposed mechanism of Y^(3+)on chitin adsorbents for the powder and ***,in addition to these interactions,pore filling/pore diffusion is the main mechanism of Y^(3+)removal in the chitin *** aerogel is efficient in concentrating 8 times the Y^(3+)from PG,a very complex *** complex chitin aerogel-Y^(3+)can be a secondary source of rare earth elements for other applications.

关键词： Rare earths Sustainable material Chitin powder Chitin porous aerogel Yttrium adsorption and recovery

Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?

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World Journal of Gastroenterology 2014年第18期20卷 5235-5243页

作者： camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves Instituto de Ciências da Saúde Universidade Federal da BahiaSalvadorBahia 41110-100Brazil

Helicobacter pylori(***)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human *** is a risk factor for gastritis,ulcer disease and stomach *** against *** is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including ***,host genetic factors that affect cytokines may determine differences in the susceptibility to many *** this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to *** and discuss how such polymorphisms may influence infection/disease outcomes.

关键词： Helicobacter pylori Stomach cancer Immunity Cytokines Polymorphisms

Biochar influences the cane fields’microbiota and the development of pre-sprouted sugarcane seedlings

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Waste Disposal and Sustainable Energy 2023年第1期5卷 75-88页

作者： Bruna Cristina pinto Adriana Barboza Alves Osania Emerenciano Ferreira Gustavo Henrique Gravatim costa Magno Andréde Oliveira Augusto Cesar da Silva Bezerra Alan Rodrigues Teixeira Machado Postgraduate Program in Environmental Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38202-436Brazil Department of Agricultural and Biological Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38208-436Brazil Postgraduate Program in Geotechnical Engineering Federal University of Ouro PretoOuro PretoMinas Gerais35400-000Brazil Department of Transport Engineering Federal Center for Technological Education of Minas GeraisBelo HorizonteMinas Gerais30421-169Brazil Department of Exact Sciences State University of Minas GeraisJoão Monlevade UnityJoão MonlevadeMinas Gerais35930-314Brazil

This research investigates the soil conditioning effect of sugar cane fields with biochar produced from sugarcane *** influence on the physicochemical and microbiological conditions of the soil and the agronomic performance of sugarcane seedlings was *** this end,the biochar from sugarcane bagasse was produced by pyrolysis in a double drum oven and mixed with soil at rates of 0,1%,3%,and 5%(in weight).The experiment was installed in a greenhouse with two evaluation periods(30 days and 60 days)and five *** pot received a pre-sprouted cane seedling,and the analysis of colony-forming units(bacteria and fungi),physicochemical characteristics of the soil,and growth and development of sugarcane were performed per *** biochar showed a high fixed carbon content(72%)and a specific surface area estimated by the adsorption of methylene blue of 50 m2 g−***,its structure is porous and contains important nutrients(e.g.,CaO,K2O,and P2O5).In the periods evaluated,the applications of the 3%and 5%(in weight)rates of biochar reduced most of the soil fertility ***,the chemical analyses indicated that the sugarcane field soil collected already possessed high *** microbiota was influenced,but only the application of the 3%(in weight)rate at 60 days after planting showed a significant positive effect on the number of bacteria forming units,with an increase of approximately 385%.On the other hand,no significant positive effect on sugarcane development was ***,biochar application in high-fertility sugarcane plantation soil did not result in gains for sugarcane development in the periods evaluated.

关键词： Soil Biometry Microbiology Double drum oven Biochar

SARS-CoV-2 and hearing:An audiometric analysis of COVID-19 hospitalized patients

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Journal of Otology 2021年第3期16卷 158-164页

作者： Francisco Alves de Sousa Rodrigo pinto costa Sandra Xará Ana Nóbrega pinto Cecília Almeida e Sousa Centro Hospitalar Universitario do Porto Serviço de Otorrinolaringologia e Cirurgia da Cabeça e Pescoço(Otorhinolaryngology and Head&Neck surgery Department)Largo Prof.Abel Salazar4099-001PortoPortugal Unidade de Saúde Familiar Garcia de Orta ACeS Porto OcidentalMedicina Geral e Familiar(Family Medicine)R.Pinho Leal 294150-620PortoPortugal Centro Hospitalar Universitario do Porto Serviço de Doenças Infeciosas(Infectious Diseases Department)Largo Prof.Abel Salazar4099-001PortoPortugal

Purpose COVID-19 associated hearing loss is still an ongoing matter of *** original studies exist on audiological effects of SARS-CoV-2 infection in hospitalized *** main objective was to determine whether SARS-CoV-2 may affect auditory function in clinically ill COVID-19 *** and methods COVID-19 patients with moderate-severe disease and without prior history of hearing abnormalities were enrolled from a tertiary referral center,and matched with *** performed an audiometric evaluation,and thresholds were *** 120 ears from 60 patients were *** with COVID-19 showed worse mean auditory thresholds starting from 1000 Hz through higher frequencies,when compared to controls(1000 Hz:18.52±5.49 dB HL in controls vs 25.36±6.79 dB HL in COVID-19,p<0.001;2000Hz:17.50±5.57 dB HL in controls vs 21.96±7.05 dB HL in COVID-19,p=0.010;3000Hz:17.97±8.07 dB HL in controls vs 25±9.38 dB HL in COVID-19,p=0.003;4000 Hz:20.16±10.12 dB HL in controls vs 29.55±11.26 dB HL in COVID-19,p=0.001;8000 Hz:31.09±12.75 dB HL in controls vs 40.71±19.40 dB HL in COVID-19,p=0.030;Pure Tone Average:20.42±4.29 dB HL in controls vs 24.85±5.62 dB HL in COVID-19,p=0.001).Statistical significance persisted after adjusting for confounders such as age,gender and various comorbidities(p<0.05).Conclusions SARS-CoV-2 may affect hearing in COVID-19 patients with moderate-severe *** are in line with the previous suggested effects of COVID-19 on auditory *** study is expected to encourage further research on this topic.

关键词： SARS-CoV-2 COVID-19 Coronavirus Audiometry Hearing

Competition among rare earth elements on sorption onto six seaweeds

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Journal of Rare Earths 2021年第6期39卷 734-741,I0005页

作者： Joāo pinto Marcelo costa Bruno Henriques JoséSoares Mariana Dias Thainara Viana Nicole Ferreira Carlos Vale JoséPinheiro-Torres Eduarda Pereira Department of Chemistry University of Aveiro3810-193 AveiroPortugal CESAM Department of ChemistryUniversity of Aveiro3810-193 AveiroPortugal LAQV-REQUIMTE Department of Chemistry&Central Laboratory of AnalysisUniversity of Aveiro3810-193 AveiroPortugal CIIMAR一Interdisciplinary Centre of Marine and Environmental Research MatosinhosPortugal N9VE-Nature Ocean and ValueLdaPortoPortugal Central Laboratory of Analysis University of Aveiro3810-193 AveiroPortugal

Sorption has been proposed as a promising approach towards a sustainable water decontamination and recently to the recycling of rare earth elements(REE).Although living seaweed have been shown to be capable of removing REE from contaminated solutions,no studies have yet compared the effects of REE competition on sorption onto different groups of *** effects were analysed in the present study by exposing six living seaweeds(Ulva lactuca,Ulva intestinalis,Fucus spiralis,Fucus vesiculosus,Gracilaria *** Osmundea pinnatifida)(3 g/L,fresh weight) to mono-element and multi-element solutions of Y,La,Ce,Pr,Nd,Eu,Gd,Tb and Dy(1 μmol/L).Results show a preference towards light REE in mono-element solutions,which is reduced when in competition with other *** competitive effect is less pronounced in heavy REE indicating that these are still able to bind to the macroalgae despite the presence of competing *** to water content(%),seaweed specific surface area(cm^(2)/g) shows to be an important factor in the sorption of REE,since larger surface area is associated with higher removal and larger competitive effect.

关键词： Bioaccumulation Wastewater e-waste Recovery Removal Marine macroalgae

“Love Is Strong, and You＇re so Sweet”： JAGGER Is Essential for Persistent Synergid Degeneration and Polytubey Block in Arabidopsis thaliana

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Molecular Plant 2016年第4期9卷 601-614页

作者： Ana Marta Pereira Margarida Sofia Nobre Sara Cristina pinto Ana Lucia Lopes Mario Luis costa Simona Masiero Silvia Coimbra Departamento de Biologia Faculdade de Ciencias da Universidade do Porto Rua do Campo Alegre 4169-007 Porto Portugal Plant Functional Genomics Group Biosystems and Integrative Sciences Institute (BiolSI) 4169-007 Porto Portugal Dipartimento di BioScienze Universita degli Studi di Milano 20133 Milan Italy Present address: Institute of Plant Biology and ZUrich-Basel Plant Science Center University of ZUrich Zolikerstrasse 107 8008 Zurich Switzerland

Successful double fertilization and subsequent seed development in flowering plants requires the delivery of two sperm cells, transported by a pollen tube, into the embryo sac of an ovule. The embryo sac cells tightly control synergid cell death, and as a result the polyspermy block. Arabinogalactan proteins are highly glycosylated proteins thought to be involved in several steps of the reproductive process. We show that JAGGER, Arabinogalactan Protein 4, is an important molecule necessary to prevent the growth of multiple pollen tubes into one embryo sac in Arabidopsis thaliana. In jagger, an AGP4 knockout mutant, the pistils show impaired pollen tube blockage as a consequence of the survival of the persistent synergid. JAGGER seems to be involved in the signaling pathway that leads to a blockage of pollen tube attraction. Our results shed light on the mechanism responsible for preventing polyspermy in Arabidopsis and for safe- guarding successful fertilization of all ovules in one pistil, ensuring seed set and the next generation.

关键词： Polytubey persistent synergid arabinogalactan proteins polyspermy

Association between EGF +61A/G polymorphism and gastric cancer in Caucasians

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World Journal of Gastroenterology 2011年第4期17卷 488-492页

作者： Ana Paula Araújo Bruno M costa Ana L pinto-Correia Maria Fragoso Paula Ferreira Mário Dinis-Ribeiro Sandra costa Rui M Reis Rui Medeiros Molecular Oncology Group Portuguese Institute of Oncology of Porto Life and Health Sciences Research Institute (ICVS) School of Health Sciences Oncology Department Portuguese Institute of Oncology of Porto Gastroenterology Department Portuguese Institute of Oncology of Porto Portugal Cintesis/Faculty of Medicine University of Porto Centro de Estudos em Biomedicina Health Sciences Faculty-Fernando Pessoa University Instituto de Ciencias Biomédicas de Abel Salazar Abel Salazar Institute for the Biomedical Sciences

AIM: To investigate the association between epidermal growth factor (EGF) +61A/G polymorphism and susceptibility to gastric cancer, through a cross-sectional study. METHODS: Polymerase chain reaction resctriction fragment lenght polymorphism analyses were used to genotype EGF +61 in 207 patients with gastric lesions (162 patients with gastric adenocarcinomas, 45 with atrophy or intestinal metaplasia) and 984 controls. All subjects were Caucasian. RESULTS: Genotype distribution was 23.5% for GG and 76.5% for GA/AA in the control group, 18.4% for GG and 68.6% for GA/AA in the entire group with gastric lesions and 17.9% for GG and 82.1% for GA/AA in the group with gastric adenocarcinoma. No statistically significant associations were found between EGF +61 variants and risk for developing gastric cancer [odds ratios (OR) = 1.41, 95% confidence intervals (CI): 0.90-2.21, P = 0.116]. However, the stratification of individuals by gender revealed that males carrying A alleles (EGF +61A/G or AA) had an increased risk for developing gastric cancer as compared to GG homozygous males (OR = 1.55, 95% CI: 1.05-2.28, P = 0.021). CONCLUSION: In summary, we found that males who were A carriers for EGF +61 had an increased risk for developing gastric cancer. This result may be explained by the suggestion that women secrete less gastric acid than men.

关键词： Epidermal growth factor polymorphism Epidermal growth factor receptor Gastric cancer