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Monitoring Multi-Temporal Changes of Lakes on the Tibetan Plateau Using Multi-Source Remote Sensing Data from 1992 to 2019: A Case Study of Lake Zhari Namco

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Journal of Earth Science 2024年第5期35卷 1679-1691页

作者： juan Wu Chang-Qing Ke Yu cai Zheng Duan Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology Key Laboratory for Land Satellite Remote Sensing Applications of Ministry of Natural ResourcesSchool of Geography and Ocean ScienceNanjing University Collaborative Innovation Center of Novel Software Technology and Industrialization Guangxi Water and Power Design Institute Co. Ltd Collaborative Innovation Center of South China Sea Studies Department of Physical Geography and Ecosystem Science Lund University

Lake level, area and volume are sensitive indicators of climate change. At present, many studies have focused on the interannual water balance of lakes, but lake level and area can change remarkably with seasons, especially for lakes with seasonal ice cover. Zhari Namco, a seasonal frozen lake, was selected as an example to investigate its seasonal water balance. Multi-source altimetry and Landsat data were used to obtain the seasonal lake level and area from 1992 to 2019, and seasonal lake volume variations were also estimated. The results indicated the average lake level, area and volume in autumn were the largest. The lake level, area, and volume experienced three turning points approximately in 2000, 2010, and 2016, and showed an overall increasing trend from 1992 to 2019, with slopes of 0.15 m/year, 2.17 km2/year, and 0.14 km3/year, respectively. The lake area expanded significantly in autumn, which was related to the abundant precipitation. Delay time of land surface runoff, increased temperature, and evaporation may be the reason for the low lake level and volume in summer. The precipitation was the dominant factor of water balance, which explained 62.09%, 62.43%, and 62.10% of the variations in lake level, area, and volume, respectively.

关键词： lake level lake area lake volume satellite altimetry landsat Zhari Namco hydrogeology

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Perspective and challenges of mycorrhizal symbiosis in orchid medicinal plants

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Chinese Herbal Medicines 2024年第2期16卷 172-179页

作者： Chunyan Leng Mengyan Hou Yongmei xing juan Chen Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine Ministry of EducationInstitute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100193China

The family Orchidaceae is of the most diverse taxon in the plant kingdom,and most of its members are highly valuable herbal *** have a unique mycorrhizal symbiotic relationship with specific fungi for carbohydrate and nutrient supplies in their whole *** large-scale cultivation of the medicinal plant Gastodia elata is a successful example of using mycorrhizal symbiotic *** this review,we adopted *** and Dendrobium officinale as examples to describe the characteristics of orchid mycorrhiza and mycorrhizal benefits for host plants’growth and health(*** and abiotic stress and secondary metabolite accumulation).The challenges in applying mycorrhizal technology to the cultivation of orchid medicinal plants in the future were also *** review aims to serve as a theoretical guide for the cultivation of mycorrhizal technology in medicinal orchid plants.

关键词： Dendrobium officinale Kimura&Migo ecological cultivation Gastodia elata Blume mycorrhiza orchid medicinal plants symbiosis mechanisms

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SimHOEPI:A resampling simulator for generating single nucleotide polymorphism data with a high-order epistasis model

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Quantitative Biology 2024年第2期12卷 197-204页

作者： Yahan Li Xinrui cai Junliang Shang Yuanyuan Zhang Jin-xing Liu School of Computer Science Qufu Normal UniversityRizhaoChina School of Information and Control Engineering Qingdao University of TechnologyQingdaoChina School of Health and Life Sciences University of Health and Rehabilitation SciencesQingdaoChina

Epistasis is a ubiquitous phenomenon in genetics,and is considered to be one of main factors in current efforts to unveil missing heritability of complex *** data is crucial for evaluating epistasis detection tools in genome-wide association studies(GWAS).Existing simulators normally suffer from two limitations:absence of support for high-order epistasis models containing multiple single nucleotide polymorphisms(SNPs),and inability to generate simulation SNP data *** this study,we proposed a simulator SimHOEPI,which is capable of calculating penetrance tables of high-order epistasis models depending on either prevalence or heritability,and uses a resampling strategy to generate simulation data *** of SimHOEPI are the preservation of realistic minor allele frequencies in sampling data,the accurate calculation and embedding of high-order epistasis models,and acceptable simulation time.A series of experiments were carried out to verify these properties from different *** results show that SimHOEPI can generate simulation SNP data independently with high-order epistasis models,implying that it might be an alternative simulator for GWAS.

关键词： high-order epistasis model penetrance table resampling strategy simulation single nucleotide polymorphisms

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Antioxidant and anti-inflammatory injectable hydrogel microspheres for in situ treatment of tendinopathy

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Regenerative Biomaterials 2024年第3期3卷 92-104页

作者： Qibin Han Lang Bai Yinhua Qian Xiaoyu Zhang juan Wang Jing Zhou Wenguo Cui Yuefeng Hao xing Yang Department of Orthopedics The Affliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical University Suzhou215008P.R.China Department of Orthopedics Kunshan Hospital of Traditional Chinese MedicineSuzhou 215300P.R.China Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025P.R.China

Tendinopathy is a common disorder that causes local dysfunction and reduces quality of *** research has indicated that alterations in the inflammatory microenvironment play a vital role in the pathogenesis of ***,injectable methacrylate gelatin(GelMA)microspheres(GM)were fabricated and loaded with heparin-dopamine conjugate(HDC)and hepatocyte growth factor(HGF).GM@HDC@HGF were designed to balance the inflammatory microenvironment by inhibiting oxidative stress and inflammation,thereby regulating extracellular matrix(ECM)metabolism and halting tendon *** growth factors with heparin was expected to improve the encaption,the catechol groups on dopamine have adhesion and antioxidant properties,allowing potential attachment at the injured site,and better function synergized with ***@HDC@HGF injected in situ in rat Achilles tendinopathy(AT)models significantly downregulated oxidative stress and inflammation,and ameliorated ECM *** conclusion,the multifunctional platform developed presents a promising alternative for the treatment of tendinopathy.

关键词： tendinopathy oxidative stress inflammation microspheres

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Event-triggered-based distributed differential game guidance laws

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Kongzhi yu Juece/Control and Decision 2024年第11期39卷 3745-3754页

作者： Xi, A-xing cai, Yuan-Li Control Engineering Research Institute Xi’an Jiaotong University Xi’an 710049 China

To reduce computational loads and save communication resources of cooperative multi-missile systems based on the event-triggered mechanism, the distributed differential game guidance laws are investigated. First, the cooperative multi-missile interception problem is converted into multi-player zero-sum differential games. The proposed guidance laws are derived by addressing the couple event-triggered-based Hamilton-Jacobi-Bellman equation, which is solved by using the adaptive dynamic programming technique. Meanwhile, adaptive weight tuning laws and event-triggered conditions are designed. The proposed guidance laws can guarantee the stability of the nonlinear multi-missile system, which is proved using the Lyapunov method. Then, the estimated weights of the neural network and consensus tracking errors are ensured to be uniformly ultimately bounded. Besides, a minimal inter-sample time is established for avoiding the Zeno behavior. Finally, some experiments are provided to illustrate the effectiveness of the proposed guidance laws. Compared with traditional distributed differential game guidance laws, the proposed guidance law reduces the number of state updates of the cooperative system controller by 65.36 %. The computational burden and communication resources of the control system can be greatly reduced. © 2024 Northeast University. All rights reserved.

关键词： Lyapunov methods

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Nano polystyrene microplastics could accumulate in Nile tilapia(Oreochromis niloticus):Negatively impacts on the intestinal and liver health through water exposure

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Journal of Environmental Sciences 2024年第3期137卷 604-614页

作者： Di Wu xing Lu Li-Xue Dong juan Tian Jin Deng Lei Wei Hua Wen Shan Zhong Ming Jiang School of Basic Medical Sciences Wuhan UniversityWuhan 430071China Key Laboratory of Freshwater Biodiversity Conservation Ministry of Agriculture and Rural AffairsYangtze River Fisheries Research InstituteChinese Academy of Fishery SciencesWuhan 430223China Hubei Province Key Laboratory of Allergy and Immunology Wuhan 430071China

Microplastics(MPs)have become a significant concern for their potential ***,the correlation between the size of plastic particles and their toxicity remains ***,we investigate the toxic effects of different sizes(80 nm,800 nm,8μm and 80μm)polystyrene MPs(PS-MPs)on the model organism Nile tilapia(Oreochromis niloticus).The results of bioluminescent imaging indicate that the 80 nm PS-MPs are more likely to invade the body.H&E staining shows severe damage on the intestinal villi and distinct hepatic steatosis in the 80 nm *** U labeling shows that the proliferation activity of intestinal and liver cells reduces significantly in the 80 nm *** gut microbiome analysis shows a severe imbalance of gut microbiota homeostasis in the 80 nm *** analysis of liver transcriptomics and metabolomics shows that the liver lipid metabolism is disordered in the 80 nm *** conclusion,this study confirms that the 80 nm PS-MPs are more likely to induce intestinal and liver *** the above lay the foundation for further study on the pathological damage of MPs to other organisms.

关键词： Microplastics(MPs) Intestinal toxicity Liver toxicity Gut microbiome Lipid metabolism

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Two new high-temperature molecular ferroelectrics[1,5-3.2.2-Hdabcn]X(X=ClO_(4)^(-),ReO_(4)^(-))

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Chinese Chemical Letters 2024年第6期35卷 234-238页

作者： Keke Han Wenjun Rao Xiuli You Haina Zhang xing Ye Zhenhong Wei Hu cai School of Chemistry and Chemical Engineering Nanchang UniversityNanchang 330031China Jiangxi Key laboratory of Organic Chemistry Jiangxi Science and Technology Normal UniversityNanchang 330013China

Molecular ferroelectrics have attracted much attention because of their excellent piezoelectricity,mechanical workability,and second harmonic ***,we successfully prepared two molecular ferroelectrics[1,5-3.2.2-Hdabcn]X(X=ClO_(4)^(-),1;ReO_(4)^(-),2)by reactions of a quasi-spherical amine 1,5-diazabicycle[3.2.2]nonane(1.5-3.2.2-dabcn)with HX aqueous *** 1 and 2 undergo hightemperature phase transitions at 381 K(1)and 396 K(2).Before and after the phase transition,they crystallize in the polar point group mm2,and the centrosymmetric point groups mmm and 4/mmm,*** to Aizu rules,these two compounds experience mmm Fmm2 and 4/mmm Fmm2 type ferroelectric phase transitions,*** ferroelectricity of both compounds is well expressed in their polycrystalline film at room temperature with low coercive voltages of 13 V for 1 and 25 V for *** piezoelectric force microscopy(PFM),the 180°anti-parallel ferroelectric domains and the reversible polarization switching can be clearly observed in 1 and *** high-temperature molecular ferroelectric material has great application potential in flexible materials,biomechanics,intelligent wearables and other fields.

关键词： Ferroelectric domains Quasi-spherical amine Phase transition Polarization

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Top 10 Trends Impacting the Beauty Industry in 2024

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China Detergent & Cosmetics 2024年第2期9卷 6-10页

作者： cai xing Wuhan Pinguan Media Co. Ltd.China

At the beginning of 2024,the cosmetic industry is bustling with prosperity and *** one hand,the perfume brand DOCUMENTS and the biotechnology company BIO-REGEN received financial *** medical company Trautec started pre-listing *** first new raw material in the new year was *** on the other hand,the packaging material company Yiside declared *** beauty brand MAOGEPING failed to go public through an IPO again,after eight years’*** Labi,Watsons and Zhonghao Biology were all mired in *** and challenge hung over the first half month of *** such a“magical”start,2024 will be definitely a year full of uncertainty.

关键词： Impact registered definitely

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Dynamically switchable porphyrin-based molecular tweezer for on-off fullerene recognition

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Chinese Chemical Letters 2024年第6期35卷 283-287页

作者： Zhimin Sun Xin-Hui Guo Yue Zhao Qing-Yu Meng Li-juan xing He-Lue Sun College of Chemistry and Materials Science Hebei Key Laboratory of Organic Functional MoleculesHebei Normal UniversityShijiazhuang 050024China

Herein,a novel molecular tweezer based on 2,2'-bipyridine-bridged porphyrin subunits was constructed for efficient fullerenes *** syn conformation of the molecule,which was obtained by Zn(Ⅱ)coordination,gives rise to a proper cavity to interact with fullerene guests to form a stable 1:1 complex in toluene *** exhibits distinct binding selectivity towards C_(60)over C_(70).Moreover,the fullerene recognition capacity can be adequately suppressed by importing H_(2)PO_(4)^(-)to competitively capture Zn(Ⅱ)along with syn-anti conformational ***,the molecular tweezer regenerated to bind the fullerene by introducing the Ca^(2+)into the ***,the association-disassociation process can be switched reversibly and repeatedly.

关键词： Molecular tweezer Fullerene recognition Supramolecular chemistry Conformation conversion Coordination

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Effect of High Suspension and Low Incision Surgery Based on Traditional Ligation of Chinese Medicine in Treatment of Mixed Haemorrhoids:A Multi-centre,Randomized,Single-Blind,Non-inferiority Clinical Trial

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Chinese Journal of Integrative Medicine 2021年第9期27卷 649-655页

作者： JIA Xiao-qiang CAO Wei-wei QUAN Long-fang ZHAO Wei-bing CHENG Fang JIA Shan FENG Liu-quan WEI Xu-feng XIE Zhen-nian WANG Dong XU Chun-yan CUI Chun-hui cai xing-juan HE Lan-ye WANG Zhan-jun TIAN Ying SHI Shu-min SUN Si-miao SU Liang ZHAI Meng-fan Department of Anorectal Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing(100091)China Department of Anorectal Beijing Rectum HospitalBeijing(100120)China Department of Anorectal Air Force Medical CenterPeople's Liberation Army of ChinaBeijing(100089)China Department of Anorectal Puyang Hospital of Traditional Chinese MedicinePuyangHenan Province(457001)China

Objective:To observe the clinical effect of high suspension and low incision(HSLI)surgery on mixed haemorrhoids,compared with Milligan-Morgan ***:A multi-centre,randomized,singleblind,non-inferiority clinical trial was *** with mixed haemorrhoids from Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing Rectum Hospital,Air Force Medical Center of People's Liberation Army of China,and Puyang Hospital of Traditional Chinese Medicine were enrolled from September 2016 to March *** using a blocked randomization scheme,participants were assigned to two *** experimental group was treated with HSLI,while the control group was treated with Milligan-Morgan *** primary outcome was the clinical effect evaluated at 12 weeks after *** secondary outcomes included the number of haemorrhoids treated during the operation,pain scores,use of analgesics,postoperative oedema,wound healing,incidence of anal stenosis,anorectal manometry after operation,as well as surgical duration,length of stay and total hospitalization expenses.A safety evaluation was also ***:In total,246 eligible participants were enrolled,with 123 cases in each *** was no significant difference in the clinical effect between the two groups(100.00% vs.99.19%,P>0.05).Compared with the control group,the number of external haemorrhoids treated during the operation and the pain scores after operation were significantly reduced in the experimental group(P0.05).The surgical duration and length of stay in the expe

关键词： mixed haemorrhoids high suspension and low incision surgery randomized controlled trial Milligan-Morgan haemorrhoidectomy

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