检索结果-南通市图书馆

comparati.e study of the effi.acy of gentami.i.-coated i.tramedullary i.terlocki.g nai. versus regular i.tramedullary i.terlocki.g nai. i. Gusti.o type i.and i. open ti.i. fractures

引用

chi.ese Journal of Traumatology 2019年第5期22卷 270-273页

作者： Deepak pinto K.Manjunatha Amarnath D.Savur Naufal Ri.wan Ahmed Sharan Mally V.Ramya Department of Orthopaedi.s Kasturba Medical College MangaloreManipal Academy of Higher EducationIndia Department of communi.y Medi.i.e Basaveshwara Medical CollegeChitradurgaIndia

Purpose:Open ti.i. fracture i. prone to i.fecti.n,consequently causi.g si.ni.i.ant morbi.i.y and i.creasi.g the hospi.al stay,occupati.nal loss and onset of chroni. *** nai.i.g i. one choi.e for treati.g ti.i. shaft *** i.prove the deli.ery of anti.i.ti.s at the ti.sue-i.plant i.terface,many methods have been proposed as a part of prophylaxi. agai.st *** study was conducted to study the role of gentami.i.-i.pregnated i.tramedullary i.terlocki.g(i.i.)nai. i. the preventi.n of i.fecti.n i. Gusti.o typeⅠandⅡopen ti.i. fractures and to compare the results wi.h regular i.tramedullary ***:The study i.cluded 28 pati.nts wi.h open ti.i. fractures(Gusti.o type 1 or type 2);of them 14 underwent regular i.i. nai.i.g and the other 14 were treated wi.h gentami.i.-coated *** was done by alternate allocati.n of the ***-up was done postoperati.ely(day 1),1 week,6 weeks,and 6 months for bone uni.n,erythrocyte sedi.entati.n rate(ESR),hemoglobi. and c?reacti.e protei.(cRP).Stati.ti.al si.ni.i.ance was tested usi.g unpai.ed t-test.A p value less than 0.05 was consi.ered ***:There were 4 cases of i.fecti.n i. controls(regular i.i. nai.)and no i.fecti.n among pati.nts treated wi.h gentami.i.-coated nai. duri.g the follow up(Х^2=4.66,p=0.031).At 6 months postoperati.ely,cRP(p=0.031),ESR(p=0.046)and hemoglobi. level(p=0.016)showed si.ni.i.ant di.ference between two *** bone heali.g rate was better wi.h gentami.i.-coated nai. i. compari.on to regular i.i. nai. at 6 months follow-up(p=0.016).conclusi.n:Gentami.i.-coated i.i. nai. has a posi.i.e role i. preventi.g i.fecti.n i. Gusti.o typeⅠandⅡopen ti.i. fractures.

关键词： Anti.i.ti. i.pregnated nai. i.tramedullary nai.i.g Open ti.i. fracture i.fecti.n

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Treatment of Vulvovagi.al candi.i.si. wi.h A Strategy Based on Phototherapy (M.A.c.^® Scar Accelerati.n Method)

引用

Modern Research i. i.flammati.n 2024年第1期13卷 1-7页

作者： Marcus Vi.i.i.s de Mello pinto Kari. Yuri.Fernández i.urra Ali.e Roni. Sampai. María Elena Si.va Álvarez Esteban Fortuny celulare i.sti.ute Petrópolis Brazil Bi.nus cli.i. Santiago Chile Fi.i.care Curicó Chile Uni.ersi.ad Fi.i. Terrae Santiago Chile

candi.i.si., also known as candi.i.si. vulvovagi.i.i., i. an i.fecti.n caused by di.ferent types of candi.a fungi. the most frequent bei.g candi.a albi.ans. The present study reports an effecti.e strategy, whi.h opens new avenues for the treatment of thi. publi. health problem. The MAc® Methodology, conventi.nal laser li.ht-emi.ti.g (LLLT)/LED) methods are based on the bi.hasi. response demonstrated many ti.es i. LLLT research and as wi.h other forms of drugs, a “drug” (i.radi.ti.n parameters) and a “dose” (i.radi.ti.n ti.es) and the “Arndt-Schulz Law” i. often ci.ed as a sui.able model to descri.e the dose-dependent effects of LLLT. Thi. method uses photopharmaceuti.als, cell markers and the use of correct parameters for each case to i.duce the accelerati.n of ti.sue repai.. The present study shows a case of a 32-year-old pati.nt di.gnosed wi.h recurrent candi.i.si. 4 years ago. Ei.hteen sessi.ns were performed (every other day) usi.g a photoacti.ated component (Methylene blue 1% + clotri.azole 1%) and LED phototherapy (red, blue and vi.let) wi.h emi.si.n ti.es of 60 - 260 seconds for each appli.ator, accordi.g to the dose recommendati.ns of the scar accelerati.n method (MAc®). At the si.th treatment sessi.n there was a noti.eable decrease i. the i.chi.g sensati.n reported by the pati.nt. i. sessi.n 11 she reported feeli.g a great i.provement, i.di.ati.g that she no longer felt i.chi.g i. any area after 18 sessi.ns. The present case demonstrates new methodologi.s to treat common problems i. the populati.n that have a posi.i.e i.pact on the quali.y of li.e. Thi. methodology has a promi.i.g future because i. i. non-i.vasi.e and requi.es a great bi.logi.al transformati.n for i.flammatory, fungal and vi.al control.

关键词： Treatment of vulvovagi.al candi.i.si. candi.i.si. candi.a M.A.c. MAc®

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Professi.nal Profi.e and the Physi.al Therapy Servi.e i. the Emergency Uni.s i. the State of São Paulo

引用

Open Journal of Emergency Medi.i.e 2021年第4期9卷 150-161页

作者： Mari.l P. Oli.ei.a Juni.r caroli.e c. Si.va Sabri.a M. cunha Augusto G. T. cruz Paulo E. J. campos Gabri.l G. Mai. Leandro M. Azeredo Marcus V. M. pinto Eli.a c. Macedo Master Student i. Health and Technology i. the Hospi.al Space Federal University of the State of Rio de Janeiro (UNIRIO) Bezerra de Araújo College (FABA) Rio de Janeiro Brazil Post-Graduate course i. Hospi.al Physi.therapy at Delta college IAPES and Physiotherapy Campos Campinas Brazil Physi.therapi.t at the State Uni.ersi.y of Ri. de Janei.o (UERJ) Rio de Janeiro Brazil Physi.therapi.t at the Mi.i.ary Poli.e Hospi.al i. Ri. de Janei.o Rio de Janeiro Brazil Researcher and cli.i.i.n at the celulare i.sti.ute (i.STcELULARE) Petrópolis Brazil Federal Uni.ersi.y of the State of Ri. de Janei.o (UNi.i.) Rio de Janeiro Brazil

The emergency room i. the entrance door of hospi.als for pati.nts who are i. ri.k of li.e, and the role of the physi.therapi.t i. thi. area i. recogni.ed as a quali.i.d member of the team, helpi.g to reduce the rate and ti.e of orotracheal i.tubati.n, judi.i.us use of i.vasi.e mechani.al venti.ati.n (MV) and non-i.vasi.e venti.ati.n (Ni.). The objecti.e was to know the profi.e and performance of physi.al therapi.ts i. the emergency departments of hospi.als i. the state of São Paulo. conducted through a semi.structured questi.nnai.e coveri.g personal and professi.nal aspects, and analyzed and descri.ed i. percentage form. Thi.ty-si. questi.nnai.es were analyzed, and i. was observed that 92% provi.e emergency care, but only 25% work exclusi.ely. Among the mai. reasons for admi.si.n to thi. sector are: acute respi.atory fai.ure (44%) and decreased level of consci.usness (36.1%). Regardi.g the physi.therapeuti. resources used i. the emergency department, 97.2% make use of Ni., followed by moni.ori.g of MV parameters (94.4%) and modi.i.ati.n of parameters (94.4%). We also found that the average ti.e of MV i. thi. sector i. 3 to 21 days (50%), and that 33% beli.ve there i. delay between i.di.ati.n and i.stallati.n of Ni.. The physi.therapi.t has much to contri.ute i. emergency uni.s, however, he must be trai.ed through the search for techni.al and sci.nti.i. knowledge, thus contri.uti.g to the consoli.ati.n of thi. area of experti.e.

关键词： Emergenci.s Physi.therapy Professi.nal Practi.e Area

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Major Approaches on the Pi.zoelectri. Devi.e, Dri.ls and Saws to Orthognathi. Surgery: A Systemati. Revi.w

引用

Health 2019年第6期11卷 783-791页

作者： Di.go césar Marques Vanessa Gabri.la Gonzáles pinto Rogéri. Lui. de Araújo Vi.n Regi. Manzi.i.Leandro Apareci.o i.razabal Pri.ci.la Janaína de Li.a Borelli.Bovo i.i.erto José Zotarelli.Fi.ho Eli.s Nai. Kassi. Uni.ersi.y center North Pauli.ta (Unorp) S&#227 o José do Ri. Preto (SP) Brazil Post Graduate and conti.ui.g Educati.n (Uni.os) S&#227 o José do Ri. Preto (SP) Brazil cri.to Redentor Hospi.al Iporá Goáis Brazil Santa casa de Mi.eri.órdi. Hospi.al Servi&#231 o de ci.urgi. e Traumatologi. Bucomaxi.ofaci.l Ribeir&#227 o Preto (SP) Brazil Uni.ersi.a de Federal do Pampa (Uni.ampa) Campus Uruguaiana (RS) Brazil

i.troducti.n: The i.ci.ence of lesi.ns of sensory and motor nerves associ.ted wi.h oral and maxi.lofaci.l surgery i. often underesti.ated, representi.g around 32.0% of all lesi.ns, and orthognathi. surgery contri.utes 12.3% to these lesi.ns. Thus, the use of pi.zosurgery (Pi.ci. has been i.di.ated i. several procedures wi.hi. oral and maxi.lofaci.l surgery due to a number of advantages over conventi.nal dri.l and saw techni.ues. Objecti.e: to analyze the mai. li.erature on the use of the pi.zoelectri. devi.e i. relati.n to the use of dri.ls and to orthognathi. surgery i. denti.try. Methods: A total of 41 arti.les were found i.volvi.g Orthognathi. Surgery, Pi.zoelectri. Devi.e, Dri.ls Devi.e, Saws Devi.e, and Effi.i.ncy. i.i.i.lly, i. was held the exclusi.n exi.ti.g ti.le and dupli.ati.ns followi.g the i.terest descri.ed thi. work. After thi. process, the summari.s were evaluated, and a new exclusi.n was held. 29 arti.les were i.cluded and di.cussed i. thi. study. i.i.i.lly, the keywords were determi.ed by searchi.g the DecS tool (Descri.tors i. Health Sci.nces, Bi.EME base) and later veri.i.d and vali.ated by MeSh system (Medi.al Subject Headi.gs, the US Nati.nal Li.rary of Medi.i.e). Results and conclusi.n: i. was concluded that the pi.zoelectri. devi.e has excelled wi.h an effecti.e surgi.al techni.ue, bei.g able to be i.di.ated i. the most di.erse areas of the oral surgery, provi.i.g accurate, clean and mi.i.ally traumati. osteotomi.s for the soft ti.sues, i.traoperati.e bleedi.g, when compared to conventi.nal surgery usi.g dri.ls and/or saws.

关键词： Orthognathi. Surgery Pi.zoelectri. Devi.e Dri.ls Devi.e Saws Devi.e Effi.i.ncy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ri.k percepti.n and knowledge of cOVi.-19 i. pati.nts wi.h celi.c di.ease

引用

World Journal of Gastroenterology 2021年第12期27卷 1213-1225页

作者： Jami. Zhen Juan Pablo Stefanolo María de la Paz Temprano caroli.e L Sei.er Alberto cami.ero Enri.ue de-Madari. Mi.uel Montoro Huguet Vi.as Santi.go Soni. i.abel Ni.eloni.Edgardo Gustavo Smecuol Lui. Uzcanga Domi.guez Elena Trucco Vi.gi.i. Lopez caroli.a Olano Pasquale Mansueto Antoni. carrocci. Peter H Green Donald Duerksen Andrew S Day Jason A Tye-Di. Juli. césar Bai.caroli.a ci.cci.Elena F Verdú Benjami. Lebwohl M i.es pinto-Sanchez Department of Medi.i.e Farncombe Family Digestive Health Research InstituteMcMaster University Medical CenterHamilton Health SciencesHamilton L8S4K1ONCanada Department of Medi.i.e Dr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Department of Pancreati. Uni. Hospital General Universitario de AlicanteAlicante 03010Spain Department of Medi.i.e Instituto Aragonés de Ciencias de la Salud(IACS)Zaragoza 50009Spain Department of Medi.i.e Hospital Universitario San Jorge.HuescaZaragoza 50004Spain Department of Gastroenterology Univ Hosp LeonGastroenterol UnitAltos de Nava S-NLeon 24071Spain Department of Medi.i.e Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico DF 14080Mexico Department of Medi.i.e Universidad de la RepublicMontevideo 11800Uruguay Department of i.ternal Medi.i.e PROMISE DepartmentUniversity of PalermoPalermo 90127Italy Department of i.ternal Medi.i.e V.Cervello HospitalPROMISE DepartmentUniversity of PalermoPalermo 90127Italy celi.c Di.ease center Columbia University Medical CenterColumbia UnivCeliac Dis CtrDiv Digest and Liver DisNew YorkNY 10032United States Department of Medi.i.e St Boniface Gen HospUniversity of ManitobaWinnipeg R2H 2A6Canada Department of Paedi.tri.s University of Otago ChristchurchChristchurch 8041New Zealand Department of Gastroenterology Royal Melbourne HospitalImmunology DivisionWalter and Eliza Hall InstituteMelbourne 3052Australia Department of Medi.i.e Surgery and DentryScuola Medica SalernitanaUniversity of SalernoCeliac Center at the University Hospital San Giovanni di Dio e Ruggi di AragonaSalerno 84131Italy Department of Medi.i.e Farncombe Family Digestive Research InstituteMcMaster UniversityHamilton L8S4K1ONCanada The celi.c Di.ease center Columbia UniversityNew YorkNY 10032United States

BAcKGROUND We recently demonstrated that the odds of contracti.g coronavi.us di.ease 2019(cOVi.-19)i. pati.nts wi.h celi.c di.ease(ceD)i. si.i.ar to that of the general ***,how pati.nts wi.h ceD percei.e thei. cOVi.-19 ri.k may di.fer from thei. actual *** To i.vesti.ate ri.k percepti.ns of contracti.g cOVi.-19 i. pati.nts wi.h ceD and determi.e the factors that may i.fluence thei. *** We di.tri.uted a survey throughout 10 countri.s between March and June 2020 and collected data on demographi.s,di.t,cOVi.-19 testi.g,and ri.k percepti.ns of cOVi.-19 i. pati.nts wi.h *** were recrui.ed through vari.us celi.c associ.ti.ns,cli.i. vi.i.s,and soci.l *** percepti.n was assessed by aski.g i.di.i.uals whether they beli.ve pati.nts wi.h ceD are at an i.creased ri.k of contracti.g cOVi.-19 when compared to the general *** regressi.n was used to determi.e the i.fluenci.g factors associ.ted wi.h cOVi.-19 ri.k percepti.n,such as age,sex,adherence to a gluten-free di.t(GFD),and comorbi.i.i.s such as cardi.c condi.i.ns,respi.atory condi.i.ns,and *** was presented as adjusted odds rati.s(aORs)RESULTS A total of 10737 parti.i.ants wi.h ceD completed the *** them,6019(56.1%)pati.nts wi.h ceD percei.ed they were at a hi.her ri.k or were unsure i. they were at a hi.her ri.k of contracti.g cOVi.-19 compared to the non-ceD populati.n.A greater proporti.n of pati.nts wi.h ceD percei.ed an i.creased ri.k of contracti.g cOVi.-19 when compared to i.fecti.ns i. general due to thei. ceD(56.1%vs 26.7%,Pconsequently,34.8%reported taki.g extra cOVi.-19 precauti.ns as a result of thei. *** of celi.c associ.ti.ns were less li.ely to percei.e an i.creased ri.k of cOVi.-19 when compared to non-members(49.5%vs 57.4%,Pci.0.99 to 0.99,Pci.0.76 to 0.93,P=0.001),and stri.t adherence to a GFD(aOR:0.89;95%ci.0.82 to 0.96,P=0.007)were associ.ted

关键词： celi.c di.ease Gluten Ri.k i.fecti.n Knowledge Percepti.n coronavi.us cOVi.-19

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

制造工艺对铝气缸盖高周疲劳耐久性的影响

引用

汽车与新动力 2013年第4期45卷 40-43页

作者： chen X F Engler-pinto c Ki.g M Li.M Prabhu E Su X 张然治

由于铸造工艺的缘故,导致气缸盖的材料高周疲劳特性分布不均匀。为了模拟制造工艺对铸件机械性能的影响,Ford汽车公司开发了虚拟铝铸造工具。虚拟铝铸造的特点之一是能预测高周疲劳强度分布。由于残余应力对气缸盖的高周疲劳也起着重要... 详细信息

由于铸造工艺的缘故,导致气缸盖的材料高周疲劳特性分布不均匀。为了模拟制造工艺对铸件机械性能的影响,Ford汽车公司开发了虚拟铝铸造工具。虚拟铝铸造的特点之一是能预测高周疲劳强度分布。由于残余应力对气缸盖的高周疲劳也起着重要作用,因此对残余应力也进行了模拟,并将其用于气缸盖的高周疲劳分析。采用ABAQUSTM软件对气缸盖总成、热应力和工作应力进行模拟。将工作应力与残余应力结合在一起,进行高周疲劳计算。采用FEMFATTM疲劳测试有限元分析软件进行高周疲劳分析。基于虚拟铝铸造模拟获得的局部材料特性,建立了用户定义的赫氏图。结果证明,利用在FEMFATTM软件中得到的局部特性分布,可显著提高气缸盖高周疲劳模拟结果的精确度。

关键词：高周疲劳耐久性铝气缸盖制造工艺虚拟铸造

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

ST段抬高心肌梗死患者冠状动脉内应用依替巴肽的效果

引用

世界核心医学期刊文摘(心脏病学分册) 2006年第4期 44-45页

作者： pinto D.S. Ki.tane A.J. Ruocco N.A. c.M. Gi.son 王海玲 Beth i.rael Deaconess Medi.al center Division of Cardiology Boston MA United States Dr.

Di.tal emboli.ati.n of atherothromboti. materi.l duri.g pri.ary percutaneous coronary i.terventi.n(Pci.i. associ.ted wi.h i.pai.ed myocardi.l perfusi.n, abnormal left ventri.ular functi.n, and hi.her mortali.y. At hi.h local concentrati.n s, glycoprotei. i.b/i.i. receptor antagoni.ts have been demonstrated to promote clot di.aggregati.n i. vi.ro. i.tracoronary admi.i.trati.n of epti.i.ati.e i. vi.vo may i.crease local drug concentrati.n by several orders of magni.ude and prom ote clot di.aggregati.n wi.h a mi.i.al i.crease i. systemi. drug concentrati.ns. We hypothesi.ed that i.tracoronary admi.i.trati.n of epti.i.ati.e before pri.ar y Pci.for ST-elevati.n myocardi.l i.farcti.n would be safe and would be associ. ted wi.h hi.h rates of normal myocardi.l perfusi.n. cli.i.al and angi.graphi. da ta were pooled from pati.nts who underwent pri.ary Pci.and recei.ed i.tracoronar y epti.i.ati.e as part of cli.i.al practi.e. i.-hospi.al adverse events were co llected retrospecti.ely. No deaths, urgent revasculari.ati.ns, or rei.farcti.ns were observed among the 59 pati.nts who were treated wi.h i.tracoronary epti.i.a ti.e. There were no Thrombolysi. i. Myocardi.l i.farcti.n(Ti.i.major bleedi.g ev ents. Two Ti.i.mi.or bleedi.g events were noted. Normal Ti.i.myocardi.l perfusi. n grade 3 flow after Pci.was noted i. 54.4%of pati.nts. No adverse events,i.cl udi.g arrhythmi.s, were noted duri.g i.tracoronary epti.i.ati.e admi.i.trati.n. i. conclusi.n, i.tracoronary epti.i.ati.e can be admi.i.tered safely duri.g pri. ary Pci.and i. associ.ted wi.h few adverse events. Relati.ely hi.h rates of norm al myocardi.l perfusi.n were observed after pri.ary Pci.wi.h adjuncti.e i.tracor onary epti.i.ati.e. Further prospecti.e randomi.ed tri.ls are warranted to evalu ate the effi.acy and safety of i.tracoronary epti.i.ati.e.

关键词：冠状动脉内依替巴肽依菲巴特心肌梗死患者 ST

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

chemi.al consti.uents from caesalpi.i. férrea:i.enti.i.ati.n and ^(1)H and ^(13)c Resonance Assi.nment

引用

Ameri.an Journal of Analyti.al chemi.try 2014年第10期5卷 688-694页

作者： i.lay Li.a Magalhaes Franci.co chagas Li.a pinto Rai.undo Braz Fi.ho Dani.le Alves Ferrei.a Telma Leda Gomes de Lemos Franci.co José Quei.oz Monte Departamento de Quími.a Organi.a e i.organi.a Universidade Federal do CearáFortalezaBrasil Laboratóri. de ci.nci.s Quími.as Centro de Ciencias TecnológicasUniversidade Estadual do Norte FluminenseCampos dos GoytacazesBrasil

i. a phytochemi.al i.vesti.ati.n of caesalpi.i. ferrea (Legumi.osae), four aromati. compounds (1-4) have been i.olated and i.enti.i.d. Thei. structures have been assi.ned based on data provi.ed by spectroscopi. techni.ues, i.cludi.g 2D NMR experi.ents. compounds 3 and 4 are bei.g reported for the fi.st ti.e for cesalpi.a ferrea.

关键词： caesalpi.i. ferrea Legumi.osae Aromati. compounds Spectral Studi.s

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Detecti.n of Heli.obacter pylori.resi.tance to clari.hromyci. and fluoroqui.olones i. Brazi.:A nati.nal survey

引用

World Journal of Gastroenterology 2016年第33期22卷 7587-7594页

作者： Bruno Squarci. Sanches Gustavo Mi.anda Marti.s Kari.e Li.a Bi.nca cota Luci.na Di.s Moretzsohn Laerci. Tenori. Ri.ei.o Heleni.e P Breyer i.mael Magui.ni. Ali.e Bessa Mai. Joffre Rezende-Fi.ho Ana caroli.a Mei.a Henri.ue pinto Edson Alves Rami.o Mascarenhas Rai.sa Passos Juli. Duarte de Souza Osmar Reni.Tri.dade Lui. Gonzaga coelho i.sti.uto Alfa de Gastroenterologi. Hospital das ClínicasUniversidade Federal de Minas Gerais Uni.astro e clíni.a Santa Fé Hospi.al de clíni.as Universidade Federal do Rio Grande do Sul Fundacao Hospi.al Adri.no Jorge Hospi.al das clíni.as Universidade Federal de Goiás Hospi.al Geral Roberto Santos

Ai. To evaluate bacteri.l resi.tance to clari.hromyci. and fluoroqui.olones i. Brazi. usi.g molecular *** The pri.ary anti.i.ti. resi.tance rates of Heli.obacter pylori.H. pylori. were determi.ed from November 2012 to March 2015 i. the Southern,South-Eastern,Northern,North-Eastern,and central-Western regi.ns of Brazi.. Four hundred ni.ety H. pylori.pati.nts [66% female,mean age 43 years(range: 18-79)] who had never been previ.usly treated for thi. i.fecti.n were enrolled. All pati.nts underwent gastroscopy wi.h antrum and corpus bi.psi.s and molecular testi.g usi.g Geno Type Heli.o DR(Hai. Li.e Sci.nce,Germany). Thi. test was performed to detect the presence of H. pylori.and to i.enti.y poi.t mutati.ns i. the genes responsi.le for clari.hromyci. and fluoroqui.olone resi.tance. The molecular procedure was di.i.ed i.to three steps: DNA extracti.n from the bi.psi.s,multi.lex ampli.i.ati.n,and reverse hybri.i.ati.n. RESULTS clari.hromyci. resi.tance was found i. 83(16.9%) pati.nts,and fluoroqui.olone resi.tance was found i. 66(13.5%) pati.nts. There was no stati.ti.al di.ference i. resi.tance to ei.her clari.hromyci. or fluoroqui.olones(P = 0.55 and P = 0.06,respecti.ely) among the di.ferent regi.ns of Brazi.. Dual resi.tance to clari.hromyci. and fluoroqui.olones was found i. 4.3%(21/490) of pati.nts. The A2147 G mutati.n was present i. 90.4%(75/83),A2146 G i. 16.9%(14/83) and A2146 c i. 3.6%(3/83) of clari.hromyci.-resi.tant pati.nts. i. 10.8%(9/83) of clari.hromyci.-resi.tant samples,more than 01 mutati.n i. the 23 S r RNA gene was noti.ed. i. fluoroqui.olone-resi.tant samples,37.9%(25/66) showed mutati.ns not speci.i.d by the Geno Type Heli.o DR test. D91 N mutati.n was observed i. 34.8%(23/66),D91 G i. 18.1%(12/66),N87 K i. 16.6%(11/66) and D91 Y i. 13.6%(9/66) of cases. Among fluoroqui.olone-resi.tant samples,37.9%(25/66) showed mutati.ns not speci.i.d by the Geno Type Heli.o DR test. cONcLUSi.N The H. pylori.clari.hromyci. resi.tance rate i. Brazi. i.

关键词： Heli.obacter pylori Mi.robi.l drug resi.tance clari.hromyci. Fluoroqui.olones Molecular di.gnosti. techni.ues

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

cli.i.al hematologi.al and bi.chemi.al parameters i. Swi.s,BALB/c,c57BL/6 and B6D2F1 Mus musculus

引用

Ani.al Models and Experi.ental Medi.i.e 2020年第4期3卷 304-315页

作者： Gi.rgi. Si.va-Santana Juli.t cunha Bax Débora cri.ti.a Si.va Fernandes Dani.la Tendler Lei.el Bacellar cleber Hooper Alexandre Alves Souza Oli.ei.a Di.s cri.ti.a Barbosa Si.va Ali.e Morei.a de Souza Si.one Ramos Ri.ardo Alexandre Santos Thai.ara Ramos pinto Mari.na Antunes Ramão Ana Luíza Mattos-Guaraldi Health Sci.nces center Institute of Microbiology Paulo de GóesFederal University of Rio de JaneiroRio de JaneiroRJBrazil Laboratory of Di.htheri. and corynebacteri. of cli.i.al Relevance Faculty of Medical SciencesUniversity of the State of Rio de JaneiroRio de JaneiroRJBrazil The collaborati.g centre for Reference and Research on Di.htheri./Nati.nal Health Foundati.n/Mi.i.try of Health Rio de JaneiroRJBrazil Laboratory of cli.i.al Research and Molecular Di.gnosti. Prof.Marcíli. Di.s do Nasci.ento Department of Clinical Practice and PathologyFluminense Federal UniversityNiteróiRJBrazil Laboratory Bacteri.l Vacci.es Department of ImmunologyNational Institute for Quality Control in HealthOswaldo Cruz FoundationRio de JaneiroRJBrazil i.sti.ute of Sci.nce and Technology i. Bi.models Oswaldo Cruz FoundationRio de JaneiroRJBrazil i.sti.ute of Bi.logy Federal Fluminense UniversityNiteróiRJBrazil Bi.medi.al center College of Medical SciencesUniversity of the State of Rio de JaneiroRio de JaneiroRJBrazil

Background:Ani.al models are wi.ely used i. sci.nti.i. research i. order to obtai. i.formati.n from a whole organi.m under a speci.i. set of experi.ental *** li.eages of mi.e have been used to i.vesti.ate di.eases and new therapeuti. strategi.s,and,consequently,hematologi.al and bi.chemi.al tests i. these laboratory ani.als are essenti.l to vali.ate sci.nti.i. *** study seeks to establi.h reference values for hematologi.al and bi.chemi.al parameters of four li.eages of ***:We evaluated the hematologi.al and bi.chemi.al profi.es of 20 males and 20 females from the li.eages Swi.s(heterogeneous),BALB/c and c57BL/6(i.ogeni.),and B6D2F1(hybri.),totali.g 160 *** were standardi.ed usi.g the systems pocH-100i. Di.f™for 19 hematologi.al parameters and Vi.ROS®350 for 12 bi.chemi.al ***:Results are shown as means and standard devi.ti.n,grouped by li.eage and *** the values obtai.ed i. thi. study wi.h the values from previ.us studi.s,some vari.ti.ns were detected,whi.h could be explai.ed by di.ferences i. methodologi.s or i.di.i.ual ***:Thus our study shows that knowledge and di.closure of the values of physi.logi.al parameters of laboratory ani.als i. necessary,and emphasi.es the i.portance of consi.eri.g vari.ti.ns i.fluenced by gender,li.eage and genotype i. the choi.e of the best experi.ental model.

关键词： B6D2F1 BALB/c bi.chemi.al c57BL/6 hematologi.al Swi.s

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：