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Simulation of Synaptic Short-term Plasticity in the Ba(cF3SO3)2-doped PEO electrolyte film device

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Simulation of Synaptic Short-term Plasticity in the Ba(CF3SO...

tFc'15全国薄膜技术学术研讨会

作者： c.t.chang F.Zeng Laboratory of Advanced Materials(MOE) School of Materials Science and EngineeringTsinghua University

Brain-like computation is a springing-up research field for the construction of novel *** the way of simulating the plasticity of bio-synapses in devices,the signal processing system based on stimulation frequency was *** the device fabricated with barium trifluoromethanesulfonate(Ba(cFSO))-doped ethylene oxide(PEO)electrolyte film,we realized two kinds of synaptic short-term plasticity(StP):short-term depression(StD)and short-term facilitation(StF).With the ionic kinetics inside the PEO matrix,a decreasing charge peak sequence and an increasing discharge peak sequence were generated under the frequency-dependent pulse mode and manifested high-pass filtering and low-pass filtering properties *** addition,apart from the response form,the operation and mechanisms of the device and bio-synapses acting StP were comparable,which were both a filter system possessing weight-changed responses,frequency-dependency and hundreds-of-millisecond ***,we constructed a history-based weight expressions to simulate the charge and discharge peaks of the device resorting to the biological excitatory post-synaptic current(EPSc)model of *** work well confirmned the simulation feasibility of the device and provided a research orientation in brain-computation.

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明潭抽水蓄能电站地下厂房洞室设计

西北水电 1991年第1期 59-64页

作者： S.c.Liu Y.cheng c.t.chang 刘琦凤

明潭(Mingtan)地下厂房洞室是台湾最大的地下厂房之一.洞室的最佳方位及形状是根据地质、应力分析和施工条件确定的.洞顶出露的平行粘土夹层采用高压水射流冲洗软弱夹层井用不收缩的砂浆回填的方法,在总体开挖前从一些小的平洞中进行处... 详细信息

明潭(Mingtan)地下厂房洞室是台湾最大的地下厂房之一.洞室的最佳方位及形状是根据地质、应力分析和施工条件确定的.洞顶出露的平行粘土夹层采用高压水射流冲洗软弱夹层井用不收缩的砂浆回填的方法,在总体开挖前从一些小的平洞中进行处理的.同时,为了加固洞顶,在开挖前从平洞中安装了具有防腐波形护套的高强度预应力锚索.岩石锚杆、预应力锚索及钢纤维喷混凝土组成的柔性支护系统在整个洞室周围形成自支撑岩体,大型地下洞室开挖中采用这种支护系统在台湾尚属首次.

关键词：洞室地下厂房洞顶预应力锚索岩石锚杆钢纤维节理面软弱夹层喷混凝土层理面

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棉花黄萎病病原菌的生理研究

沈阳农学院学报 1956年第1期 55-62页

作者：韦石泉张际中

1.棉黄萎病病原菌,经鉴定后,采用 Verticillium albo-atrum Reinke et Berthold学名。2.最适本病原菌生育的培养基,以改良 czepek’s 组合和马铃薯培养基为最好,在这两种培养基上菌丝生长旺盛,经过4—5天后都能生很多分生孢子,并渐生成... 详细信息

1.棉黄萎病病原菌,经鉴定后,采用 Verticillium albo-atrum Reinke et Berthold学名。2.最适本病原菌生育的培养基,以改良 czepek’s 组合和马铃薯培养基为最好,在这两种培养基上菌丝生长旺盛,经过4—5天后都能生很多分生孢子,并渐生成小菌核。3.本病原菌的发育温度以17°—28℃较好、其中尤以25℃最好。孢子发芽温度以15°—20℃篇最好、在1%葡萄糖液中发芽最好。但在灭菌水中发芽亦好,对营养的要求并不太高。4.本病原菌自苗期(具四真药)开始直至后期,皆能侵入棉株内部,其中尤以用孢子悬浮液于棉根附近接种的办法,得知在开花期至结铃期皆能显现较高的发病率、根据实验记载,在棉花生育期中,接种后一般8—16天左右即能现出病征,此比前人记载期限较早。

关键词：病原菌苗期子登棉黄萎病黄萎病菌生理研究

Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith teo En Ning chang Liu Yu-chi Liu tissue Engineering and Stem cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. this review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. this review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. this should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

A correlation between pulse diagnosis of human body and health monitoring of structures

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Earthquake Engineering and Engineering Vibration 2004年第1期3卷 117-125页

作者： c.c.chang Henry t.Y.Yang Department of civil Engineering Hong Kong University of Science and TechnologyHong Kong Department of Mechanical and Environmental EngineeringUniversity of California Department of Mechanical and Environmental Engineering University of California

the concept of health monitoring is a key aspect of the field of medicine that has been practiced for a long time. A commonly used diagnostic and health monitoring practice is pulse diagnosis, which can be traced back approximately five thousand years in the recorded history of china. With advances in the development of modern technology, the concept of health monitoring of a variety of engineering structures in several applications has begun to attract widespread attention. Of particular interest in this study is the health monitoring of civil structures. It seem natural, and even beneficial, that these two health-monitoring methods, one as applies to the human body and the other to civil structures, should be analyzed and compared. In this paper, the basic concepts and theories of the two monitoring methods are first discussed. Similarities are then summarized and commented upon. It is hoped that this correlation analysis may help provide structural engineers with some insights into the intrinsic concept of using pulse diagnosis in human health monitoring, which may of be some benefit in the development of modern structural health monitoring methods.

关键词： human health monitoring pulse diagnosis structural health monitoring vibration-based techniques local detection techniques

comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li cui chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Aligned Ion conduction Pathway of Polyrotaxane‑Based Electrolyte with Dispersed Hydrophobic chains for Solid‑State Lithium–Oxygen Batteries

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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram Kim Myeong‑chang Sung Gwang‑Hee Lee Byoungjoon Hwang Sojung Seo Ji‑Hun Seo Dong‑Wan Kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and chemical Engineering center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

Metal-organic frameworks with dinuclear metal centers for synergistically boosting cO2 photoreduction

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Science china chemistry 2025年第01期 201-208页

作者： Hui-Feng Wang Wen-Jie Shi Yu-Xin Yang Bao-Xia Dong tong-Bu Lu Di-chang Zhong School of chemistry and chemical Engineering Yangzhou University Institute for New Energy Materials and Low carbon technologies School of Materials Science and Engineering Tianjin University of Technology

Dinuclear metal synergistic catalysis （DMSc） has been proved powerful in boosting cO2reduction,while this has not been achieved in heterogeneous catalysts with long-range order *** this study,we,by introduction of metal catalytic centers into an indium-based metal-organic framework （MOF）,obtained a series of isostructural In-MOFs,including three MOFs with mononuclear metal catalytic center （M-In）,three MOFs with dinuclear homometallic catalytic centers （MM-In）,and three MOFs with dinuclear heterometallic catalytic centers (MM’-In,M/M’=co（II）,Ni（II）,Zn（II）).It was found that all these MOFs can serve as catalysts for photochemical cO2reduction to *** with M-In,the catalytic activities of MM-In were obviously enhanced,and that of MM’-In was further significantly *** example,the cO yield of co Zn-In reaches a record value of 12,700μmol g-1h-1,which is 4.0,8.1,9.4,and 18.6-fold higher than that of co co-In,Zn Zn-In,co-In,and Zn-In,***,the catalytic activities of co Ni-In and Ni Zn-In also show different fold increase than those of corresponding dinuclear homometallic and mononuclear metallic *** results of control experiments and theoretical calculation reveal that the higher catalytic activities of MM-In over M-In can be ascribed to the DMSc effect,and the higher catalytic activity of MM’-In over MM-In can be ascribed to the strengthened DMSc *** work reveals the relationship between DMSc effect and bimetal centers in cO2reduction,which provides new insights into the DMSc and paves a new way to design highly active catalysts for photochemical cO2reduction.

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