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Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for next‑Generation Flexible Optoelectronics

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nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.nirmal Tukaram d.dongale Atul c.Khot chenjie Yao nahyun Kim Tae Geun Kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea computational Electronics and nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

Acquired sensorineural hearing loss,oxidative stress,and microRnAs

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neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： desmond A.nunez Ru c.Guo division of Otolaryngology–Head&neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada division of Otolaryngology–Head&neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RnA sequences known as microRnAs(miRnAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEdLInE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRnAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRnAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRnAs oxidative stress sensorineural

Multiple sclerosis is at a checkpoint: advancing the program

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neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams department of neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA department of biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cnS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： carina Hromada Patrick Heimel Markus Kerbl LászlóGál Sylvia nürnberger Barbara Schaedl James Ferguson nicole Swiadek Xavier Monforte Johannes c.Heinzel Antal nógrádi Andreas H.Teuschl-Woller david Hercher department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University clinic of dentistry Medical University of ViennaViennaAustria department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tnGcs). However, the use of tnGcs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tnGc would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tnGcs and compared the various features of these improved silk^(+) tnGcs with the tubes without holes(silk^(–) tnGcs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tnGcs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tnGcs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tnGcs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tnGcs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

Serological surveillance for SARS-coV-2 antibodies among students,faculty and staff within a large university system during the pandemic

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World Journal of Virology 2025年第1期14卷 99-107页

作者： Marcos G Pinheiro Gabriela G O Alves Maria Eduarda R conde Sofia L costa Regina c S Sant’Anna Isa M F Antunes Mônica c carneiro Fabio S Ronzei Julia c Scaffo Felipe R Pinheiro Lialyz S Andre Helvecio c Povoa Valéria T Baltar Fabíola Giordani Eduarda S Hemerly Gisele c Alexandre Karla c de Paula Márcio Watanabe Antonio claudio L da nóbrega Jackeline christiane P Lobato Fabio Aguiar-Alves Laboratory of Molecular Epidemiology and biotechnology Rodolpho Albino University LaboratoryFluminense Federal UniversityNiterói 24241000Rio de JaneiroBrazil Estácio de SáUniversity Nova Friburgo 28611135Rio de JaneiroBrazil Pathology Program Medicine schoolFluminense Federal UniversityNiterói 24070090Rio de JaneiroBrazil department of Pharmaceutical Sciences Lloyd L.Gregory School of PharmacyPalm Beach Atlantic UniversityWest Palm BeachFL 33401United States Health Institute of nova Friburgo Fluminense Federal UniversityNova Friburgo 28613001Rio de JaneiroBrazil department of Epidemiology and biostatistics Institute of Collective Health(ISC)Fluminense Federal UniversityNiterói 24033900Rio de JaneiroBrazil Institute of Physical Education Fluminense Federal UniversityNiterói 24020005Rio de JaneiroBrazil department of Statistics Fluminense Federal UniversityNiterói 24210200Rio de JaneiroBrazil department of Physiology and Pharmacology Fluminense Federal UniversityNiterói 24210130Rio de JaneiroBrazil

BAcKGROUnd At the end of december 2019,the world faced severe acute respiratory syndrome-coronavirus 2(SARS-coV-2),which led to the outbreak of coronavirus disease 2019(cOVId-19),associated with respiratory *** virus has shown significant challenges,especially for senior citizens,patients with other underlying illnesses,or those with a sedentary *** tests conducted early on have helped identify how the virus is transmitted and how to curb its *** study hypothesis was that the rapid serological test for SARS-coV-2 antibodies could indicate the immunoreactive profile during the cOVId-19 pandemic in a university *** To conduct active surveillance for serological expression of anti-SARS-coV-2 antibodies in individuals within a university setting during the cOVId-19 *** This sectional study by convenience sampling was conducted in a large university in niteroi-RJ,Brazil,from March 2021 to July *** study population consisted of students,faculty,and administrative staff employed by the university.A total of 3433 faculty members,60703 students,and 3812 administrative staff were invited to *** were gathered through rapid serological tests to detect immunoglobulin(Ig)M and IgG against ***χ²or Fisher's exact test was used to conduct statistical analysis.A 0.20 significance level was adopted for variable selection in a multiple logistic regression model to evaluate *** A total of 1648 individuals were enrolled in the *** proportion of cOVId-19 positivity was 164/1648(9.8%).The adjusted logistic model indicate a positive association between the expression of IgM or IgG and age[odds ratio(OR)=1.16,95%cI:1.02-1.31](Pndividuals who had been in contact with a cOVId-19-positive case(OR=3.49,95%cI:2.34-5.37)(Pd received the cOVId-19 vaccine(OR=2.33,95%cI:1.61-3.35)(Pnd social isolation(OR=0.59,95%cI:0.41-0.84)(Pd of sho

关键词： Serological surveillance SARS-coV-2 antibodies cOVId-19 Serological rapid test Risk factors for cOVId-19

characteristics of urban ozone level in Hong kong

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Journal of Environmental Sciences 2001年第1期13卷 1-7页

作者： d.Y.c.LEUnG d.n.ZHAnG department of Mechanical Engineering The University of Hong KongPokfulam RoadHong KongChina Research Institute of Environmental Engineering East China University of Science and TechnologyShanghai 200237China

The long term trend of ozone level in Hong Kong has been investigated. One of the characteristics of ozone level in Hong Kong is the existence of autumn maximum and summer minimum. Observations of the diurnal variation of ozone level have been made in different area categories. There are early morning peak and afternoon peak occurred in the diurnal variation, which are different from some metropolitans where only an afternoon peak is observed. A negative correlation coefficient was found between monthly ozone level with nitric oxide level. On the contrary, there is a positive correlation between ozone and nitrogen dioxide. The positive correlation coefficient between nitric oxide and nitrogen dioxide shows that the total amount of nitric oxide emitted from a series of moving and fixed sources greatly exceeded the stoichiometric amount of ozone formed from chemical reactions of precursors and long distance transportation.

关键词： ozone urban air pollution Hong kong china

Magnetocaloric effect in Erni2 melt-spun ribbons

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Journal of Rare Earths 2020年第6期38卷 612-616页

作者： J.L.Sanchez Llamazares P.Ibarra-Gaytan c.F.Sanchez-Valdes d.rlos-Jara P.Alvarez-Alonso Instituto Potosino de Investigacion ciendfica y Tecnoldgica A.c. Camino a la Presa San Jose 2055Col.Lomas 4San Luis Potosi.S.LP.78216Mexico cPM-TIP University Pavol Jozef SafarikPark Angelinum 9.04154 KosiceSlovakia division Multidisciplinaria Ciudad UniversitariaUniversidad Aurdnoma de Ciudad Juarez(UACJ)Calle Jose de Jesus Macias Delgado#18100Ciudad Juarez 32579Chihuahua.Mexico departamento de Fisica Universidad de OviedoCalvo Sotelo s/n33007 OviedoSpain

Erni2 ribbons were produced by rapid solidification using the melt spinning *** structural,magnetic and magnetocaloric properties in the as-solidified state were studied by X-ray diffraction,scanning electron microscopy,magnetization and specific heat *** are single phase with the Mgcu2-type crystal structure,a curie temperature Tc of 6.8 K and a saturation magnetization at2 K and 5 T of 124.0 A·m2/*** a magnetic field change μ0△H of 5 T(2 T) ribbons show a maximum magnetic entropy change |△SMpeak| of 24.1(16.9) J/(kg·K),and an adiabatic temperature change △Tadmax of8.1(4.4) K;this is similar to the previously reported literature for bulk alloys that were processed through conventional melting techniques followed by prolonged thermal *** addition,the samples also show slightly wider △SM(T) curves with respect to bulk alloys leading to a larger refrigerant capacity.

关键词： Erni2 Laves phase Melt-spun ribbons Magnetic entropy change Adiabatic temperature change Rare Earths

creeping fat and gut microbiota in crohn’s disease

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World Journal of Gastroenterology 2025年第1期31卷 16-23页

作者： Ana EV Quaglio daniéla O Magro Marcello Imbrizi Ellen cS de Oliveira Luiz c di Stasi Ligia Y Sassaki Verum Ingredients Botucatu Technology ParkBotucatu 18605-525São PauloBrazil department of Surgery Faculty of Medical SciencesState University of CampinasCampinas 13083-970São PauloBrazil department of Gastroenterology Faculty of Medical SciencesUniversity of CampinasCampinas 13083-970São PauloBrazil department of Internal Medicine Medical SchoolSão Paulo State UniversityBotucatu 18618-686São PauloBrazil department of biophysics and Pharmacology Institute of BiosciencesSão Paulo State UniversityBotucatu 18618-689São PauloBrazil

In this article,we explored the role of adipose tissue,especially mesenteric adipose tissue and creeping fat,and its association with the gut microbiota in the pathophysiology and progression of crohn’s disease(cd).cd is a form of inflammatory bowel disease characterized by chronic inflammation of the gastrointestinal tract,influenced by genetic predisposition,gut microbiota dysbiosis,and environmental *** microbiota plays a crucial role in modulating immune response and intestinal inflammation and is associated with the onset and progression of ***,visceral adipose tissue,particularly creeping fat,a mesenteric adipose tissue characterized by hypertrophy and fibrosis,has been implicated in cd pathogenesis,inflammation,and *** bacteria from the gut microbiota may translocate into mesenteric adipose tissue,contributing to the formation of creeping fat and influencing cd *** creeping fat may be a protective barrier against bacterial invasion,its expansion can damage adjacent tissues,leading to *** gut microbiota through interventions such as fecal microbiota transplantation,probiotics,and prebiotics has shown potential in managing ***,more research is needed to clarify the mechanisms linking gut dysbiosis,creeping fat,and cd progression and develop targeted therapies for microbiota modulation and fat-related complications in patients with cd.

关键词： creeping fat Mesenteric adipose tissue Gut microbiota crohn’s disease Inflammatory bowel disease

THE STRESS-EnERGY TEnSOR And POHOZAEV'S IdEnTITY FOR SYSTEMS

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Acta Mathematica Scientia 2012年第1期32卷 433-439页

作者： n.d.Alikakos A.c.Faliagas department of Mathematics University of Athens

Utilizing stress-energy tensors which allow for a divergence-free formulation, we establish Pohozaev＇s identity for certain classes of quasilinear systems with variational structure.

关键词： calculus of variations stress-energy tensor p-Lapacian minimal surface