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Genes & Diseases 2024年第2期11卷 589-592页

作者： Maria Papatsirou Andreas Scorilas Diamantis c.Sideris c.ristos k.kontos Department of Biochemistry and Molecular Biology National and Kapodistrian University of AthensPanepistimiopolisAthens GR 15701Greece

Long-read sequencing with nanopore technology has been widely utilized for the identification of the full-length sequence of RNA molecules."It is especially suitable for the identification of circular RNAs(circRNAs),which are regulatory molecules that are regarded as promising non-invasive biomarkers for various human malignancies,including breast cancer.2 The impact of circRNAs derived from the protein arginine methyltransferase 1(PRMT1)gene has not been clarified yet,even though the effect of PRMT1-mediated methylation on breast cancer cell characteristics has been well established.

关键词： PRMT1 breast cancer

comparison of Patent Foramen Ovale and Aortic Atherosclerosis in Patients with cryptogenic Ischemic Stroke or Transient Ischemic Attack

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Comparison of Patent Foramen Ovale and Aortic Atherosclerosi...

Relationship between the Incidence,Location and Extent of Atherosclerosis in the Thoracic Aorta and the Extent of coronary Artery Disease

中华医学会第十次全国超声医学学术会议

作者： Michael c.kontos Walter Paulsen James Arrowood JV Nixon Virginia commonwealth University RichmondVA Beijing Anzhen Hospital

Background:cryptogenic stroke(cS) represent a diagnostic *** studies have shown an association between the presence of a patent foramen ovale(PFO) and cS in patients<55 years *** addition, protruding atheromas in the ...

Background:cryptogenic stroke(cS) represent a diagnostic *** studies have shown an association between the presence of a patent foramen ovale(PFO) and cS in patientscending aorta and aortic arch are an independent risk factor for ischemic stroke in

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Relationship between the Incidence,Location and Extent of At...

伴肾衰竭和肌钙蛋白I升高的胸痛住院患者的预后

中华医学会第十次全国超声医学学术会议

作者： Michael c.kontos Walter HJ Paulsen James A Arrowood George W.Vetrovec J V Nixon Beijing Anzhen Hospital BeijingPeople's Republic of China Virginia commonwealth University

Background:Atherosclerotic lesions in the thoracic aorta detected by transesophageal echocardiography (TEE) have been correlated with coronary artery disease(cAD).We determined whether simple or complex aortic plaques seen on TEE correlated with the extent,location and severity of aortic atherosclerosis with cAD. Methods:The study population consisted of 188 TEE patients who also underwent coronary ***-

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世界核心医学期刊文摘(心脏病学分册) 2006年第2期 27-28页

作者： kontos M. c. Garg R. Anderson F. P. 吴晓燕 Heart Station North Hospital PO Box 980051 Richmond VA 23298-0051 United States Dr.

Background: The significance of troponin I(TnI) elevations in patients with renal failure(RF) admitted for possible myocardial ischemia is unclear. We therefore compared outcomes in patients with and without TnI elevations based on renal function. Methods:consecutive patients without ST elevation admitted for exclusion of ischemia underwent serial assessment of cardiac markers including TnI. coronary angiography, significant disease, and revascularization were determined, and 1-year cardiac mortality and all-cause mortality were assessed. Mortality was assessed based on TnI elevations in patients with no(creatinine clearance crcl ≥ 60 mL/min), moderate(crcl 30-59 mL/min), and severe(crclconsecutive patients and were significantly more frequent in patients with RF(crclcrcl 30-59 mL/min: 19% ; crcl≥ 60 mL/min: 13% , all P≤ .01). coronary angiography was performed significantly less frequently in patients with RF, whether TnI elevations were present. One-year all-cause mortality increased with both RF and TnI positivity(TnI + vs TnI -, crclcrcl 30-59 mL/min: 21% vs 14% ; crcl≥ 60 mL/min: 8.9% vs 4.9% , all Pctor of mortality in the 3 RF groups(odds ratio 3.3 for crcl crcl 30-59 mL/min, and 3.3 for crcl≥ 60 mL/min). conclusions: Troponin I elevations identified a high-risk cohort, and its prognostic value was not diminished in patients with RF.

关键词：肾衰竭患者肌钙蛋白肌肉蛋白全因死亡

2-6 First Direct Measurement of 12c(12c, n)23Mg at Stellar Energies

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IMP & HIRFL Annual Report 2015年第1期 56-58页

作者： Tang Xiaodong B. Bucher X. Fang A. Heger S. Almaraz-calderon A. Alongi A.D. Ayangeakaa M. Beard A. Best J. Browne c. cahillane M. couder R.J. deBoer A. kontos L. Lamm Y.J. Li A. Long W. Lu S. Lyons M. Notani D. Patel N. Paul M. Pignatari A. Roberts D. Robertson k. Smith E. Stech R. Talwar W.P. Tan M. Wiescher S.E. Woosley Institute of Modern Physics Chinese Academy of Science Lanzhou 730000 China Institute for Structure and Nuclear Astrophysics Joint Institute for Nuclear AstrophysicsUniversity of Notre Dame Notre Dame Indiana 46556 USA Lawrence Livermore National Laboratory Livermore California 94550 USA Monash center for Astrophysics School of Physics and Astronomy Monash University Victoria 3800 Australia Department of Physics and Astronomy Shanghai Jiao-Tong University CNA Shanghai 200240 China School of Physics and Astronomy University of Minnesota Minneapolis Minnesota 55455 USA china Institute of Atomic Energy Beijing 102413 China konkoly Observatory Research Centre for Astronomy and Earth Sciences Hungarian Academy of SciencesKonkoly Thege Mikl′os′ut 15-17 H-1121 Budapest Hungary Department of Physics University of Basel Basel CH-4056 Switzerland Department of Astronomy and Astrophysics University of California Santa Cruz California 95064 USA

The first stars in the early Universe were formed about 400 million years after the big bang. Verification of the existence of these stars is important for our understanding of the evolution of the Universe[1]. It has been predicted that for Population-III stellar production yields, the abundances of odd-Z elements are remarkably deficient compared to their adjacent even-Z elements[2]. Astronomers are searching for long-lived, low mass stars with the unique nucleosynthetic pattern matching the predicted yields[3].

关键词： First Direct Measurement

数字乳腺X线摄影和中心组合断层投照对乳腺密度百分比的估算

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国际医学放射学杂志 2009年第5期32卷 483-483页

作者： P.R.Bakic A.k.carton D.kontos c.Zhang A.B.Troxel A.Maidment 秦乃姗 Department of Radiology University of Pennsylvania

目的评价临床数字乳腺X线摄影与中心组合数字乳腺断层（DBT）投照成像估算乳腺密度百分比（PD）读片者间和同一读片者内的一致性。材料与方法本研究经学术委员会通过并符合健康医疗保险要求，所有病人均签署知情同意书。对39例女性（31... 详细信息

目的评价临床数字乳腺X线摄影与中心组合数字乳腺断层（DBT）投照成像估算乳腺密度百分比（PD）读片者间和同一读片者内的一致性。材料与方法本研究经学术委员会通过并符合健康医疗保险要求，所有病人均签署知情同意书。对39例女性（31～80岁．平均年龄51岁）的匿名数字乳腺x线摄影和中心DBT投照行乳腺PD估算。

关键词：乳腺X线摄影乳腺密度估算投照中心组合断层乳腺x线摄影学术委员会

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学前儿童关于故事的知识:综合性观点

心理发展与教育 1987年第3期 24-24页

作者： Susan kontos ,Holly Mackley ,Joyce Graham Baltas ,郑龙

本研究调查了当用与为交谈目的而进行的口头讲话不同的书面语来叙述故事时,学前儿童对故事的结构和成分了解的情况。本研究的一个主要的目的,就是要通过按照不同调查者分别观察到的典型变量来分析学前儿童所讲的同一组故事,从而概括出... 详细信息

本研究调查了当用与为交谈目的而进行的口头讲话不同的书面语来叙述故事时,学前儿童对故事的结构和成分了解的情况。本研究的一个主要的目的,就是要通过按照不同调查者分别观察到的典型变量来分析学前儿童所讲的同一组故事,从而概括出一个综合性的观点。被试是33名三、四和五岁的儿童,要求他们复述一个相似的故事“三个小猪”,对被试最后写出的故事的分析是根据(a)是否出现Stein和Glenn故事语法规则中所包括的六个范畴;(b)故事结构的复杂性;(c)规范的故事特征的使用和(d)记叙文的构思。结果显示,年龄不是故事知识的灵敏预测物,言语能力才是更有效的预测物。本研究的统计数据表明,学前儿童对故事内容知识的掌握先于对结构知识的掌握。

关键词：学前儿童被试故事民间文学

肌钙蛋白诊断时期,射血分数和肾衰竭对无ST段抬高胸痛住院患者的预测价值

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世界核心医学期刊文摘(心脏病学分册) 2006年第2期 27-27页

作者： kontos M. c. Garg R. Anderson F. P. 吴晓燕 Heart Station North Hospital Medical College of Virginia 12th and 1300 E.Marshall Sts Richmond VA 23298-0051 United States Dr.

Background: Ejection fraction(EF) and renal failure(RF) are powerful predictors of mortality in patients with myocardial infarction(MI). There are limited data assessing the predictive value of EF and RF compared with clinical variables in patients without ST elevation using troponin as the diagnostic MI criteria. Methods: consecutive patients admitted from the emergency department underwent serial assessment of cardiac markers, including troponin I. Abnormal EF was defined ascreatinine clearance(crcl) compare clinical variables, crcl, and EF for predicting short-and long-term outcomes. Results: A total of 3074 patients had EF assessed. Mild to moderately reduced EF and crcl were present in 639(21% ) and 582(19% ) patients, with 403(13% ) and 233(7.6% ) having severe systolic dysfunction and severe RF, respectively. Abnormal EF and RF were both present in 13% of patients(1-year mortality 26% ), whereas 52% had both normal EF and crcl(1-year mortality 3.2% ). The presence of either systolic dysfunction or RF increased mortality 3-to 4-fold compared with patients without either. The most important multivariate predictors of 1-year mortality were EF(OR 2.6 95% cI 1.7-3.8, Pcrcl(OR 2.8 95% cI 1.8-4.2, Pconclusions: Both RF and EF are strong predictors of cardiac mortality in patients admitted for exclusion of MI. Prediction models that do not include these 2 variables will underestimate risk.

关键词：肾衰竭患者射血分数肌钙蛋白肌肉蛋白预测价值 ST

乳腺数字化断层摄影分析乳腺实质结构评估罹患乳腺癌风险:与乳腺数字化摄影比较

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国际医学放射学杂志 2011年第6期 587-587页

作者： D.kontos L.c.Ikejimba P.R.Bakic A.B.Troxel E.F.conant A.D.A.Maidment 张小玲 Department of Radiology University of Pennsylvania Health System1 Silverstein Bldg HUP3400 Spruce StPhiladelphia PA 19104-4206

目的乳腺密度百分比(PD)是已被确认的罹患乳腺癌的风险因子,本研究目的是在筛查人群中评估数字化乳腺断层摄影(DBT)与数字化乳腺摄影显示的乳腺实质结构特征与PD的相关性。材料与方法本研究经专业委员会核准,受试者均签署书面知情同意... 详细信息

目的乳腺密度百分比(PD)是已被确认的罹患乳腺癌的风险因子,本研究目的是在筛查人群中评估数字化乳腺断层摄影(DBT)与数字化乳腺摄影显示的乳腺实质结构特征与PD的相关性。材料与方法本研究经专业委员会核准,受试者均签署书面知情同意书。回顾性分析2007年7月—2008年3月进行的一项经专业委员会批准的DBT筛查

关键词：乳腺癌 DBT 乳腺肿瘤乳腺实质数字化乳腺摄影断层摄影