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Artificial intelligence analysis of videos to augment clinical assessment:an overview

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Neural Regeneration Research 2024年第4期19卷 717-718页

作者： David c.wong Stefan Williams University of leeds leeds Teaching Hospitals Trust LeedsUK

Observation is a fundamental part of the practice of clinical *** of movement is particularly important for the *** such as Parkinson’s disease,multiple sclerosis,stroke,epilepsy,and many others affect a person’s movement in characteristic *** some conditions,changes in the patient’s voice can be included in this-changes in sound caused by changes in the movements of *** clinician’s detection of a characteristic abnormality,and their judgment of its severity,plays a central role in both diagnosis and the assessment of prognosis or response to ***,that practice depends upon a limited resource of experienced *** addition,these experts are limited by human visual judgment,which cannot reliably or precisely detect and measure small or subtle changes in movement(Williams et al.,2023).

关键词： clinical epilepsy diagnosis

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RNA的质谱分析研究进展

生命科学 2014年第3期26卷 261-269页

作者：彭超黄超兰中国科学院上海生命科学研究院生物化学与细胞生物学研究所国家蛋白质科学中心上海201210

核糖核酸(RNA)是一类重要的遗传物质,在生物体内起着至关重要的作用。传统的RNA测序鉴定技术既费时又费力,而且会丢失大量的RNA转录后修饰等方面的信息。随着近年来仪器的更新和技术的飞速发展,质谱技术在生物大分子研究方向得到了很好... 详细信息

核糖核酸(RNA)是一类重要的遗传物质,在生物体内起着至关重要的作用。传统的RNA测序鉴定技术既费时又费力,而且会丢失大量的RNA转录后修饰等方面的信息。随着近年来仪器的更新和技术的飞速发展,质谱技术在生物大分子研究方向得到了很好的应用,特别是基于质谱技术的蛋白质组学。相比蛋白质组学的研究来说,基于质谱技术的RNA鉴定分析更为困难,发展相对缓慢。但是,硬件方面的革新和软件方面的开发也为其发展带来了很好的契机。重点通过对质谱技术在RNA分析鉴定的介绍,从样品制备、离子化方式、碎裂方式、分析方法、数据后处理软件等几个方面展现了基于质谱技术的RNA研究进展。

关键词：电喷雾电离基质辅助激光解吸电离静电场轨道阱核糖核酸数据库检索

Structural insights into POT1-TPP1 interaction and POT1 c-terminal mutations in human cancer

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Structural insights into POT1-TPP1 interaction and POT1 C-te...

Do we really need a standardized approach to spontaneously ruptured hepatocellular carcinoma?

中国生物化学与分子生物学会2016年全国学术会议

作者： cong chen Peili Gu Jian Wu Xianyun chen Shuangshuang Niu lijie Wu Na li Junhui Peng cuiying Fan Min Huang catherine c.l.wong Qingguo Gong Rongguang Zhang lajos Pusztai Sandy chang Ming lei National center for Protein Science Shanghai State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai Research center Chinese Academy of Sciences Department of Pathology and 5Department of Medicine Yale School of Medicine National laboratory for Physical Science at the Microscale and School of life Sciences University of Science and Technology of China

Mammalian shelterin proteins POT1 and TPP1 form a stable heterodimer that protects chromosome ends and regulates telomerase-mediated telomere ***,how POT1 interacts with TPP1 to form a heterodimer remains *** we prese... 详细信息

关键词： Telomere POT1 TPP1 crystal structure Human cancer

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Hepatobiliary Surgery and Nutrition 2024年第1期13卷 191-193页

作者： Tomoki Sempokuya linda l.wong Division of Gastroenterology and Hepatology Department of MedicineJohn A.Burns School of MedicineUniversity of Hawaii at ManoaHonoluluHIUSA Department of Surgery John A.Burns School of MedicineUniversity of Hawaii at ManoaHonoluluHIUSA

Hepatocellular carcinoma(Hcc)is one of the leading causes of cancer-related death in Asian and African countries due to a high prevalence of chronic hepatitis B infections(1,2).The vast majority of current studies focus on the treatment of Hcc itself rather than complications from Hcc.A potentially life-threatening complication of Hcc is spontaneous rupture,and its prevalence has been reportedly to be 5-15%of all Hcc cases(1).This is the third leading cause of Hcc-related death after tumor progression and liver failure,and there is a high mortality associated with rupture(3,4).

关键词： Hepatocellular carcinoma(Hcc) spontaneous rupture liver resection trans-arterial embolization(TAE)

The electroweak monopole–antimonopole pair in the standard model

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communications in Theoretical Physics 2024年第3期76卷 113-119页

作者： Dan Zhu Khai-Ming wong Guo-Quan wong School of Physics Universiti Sains Malaysia11800 USMPenangMalaysia

We present the first numerical solution that corresponds to a pair of cho–Maison monopoles and antimonopoles(MAPs) in the SU(2) × U(1) Weinberg–Salam(WS) *** monopoles are finitely separated,while each pole carries a magnetic charge ±4π/*** positive pole is situated in the upper hemisphere,whereas the negative pole is in the lower *** cho–Maison MAP is investigated for a range of Weinberg angles,0.4675≤ tan θ_(W)≤10,and Higgs self-coupling,0 ≤ β ≤ *** magnetic dipole moment(μm) and pole separation(d_(z)) of the numerical solutions are calculated and *** total energy of the system,however,is infinite due to point singularities at the locations of monopoles.

关键词： magnetic monopole cho-Maison monopole Weinberg-Salam model

langmuir-Schaefer Film Investigation and Density Functional Theory Band Gap calculations of calix[n]arene-Para-Aminobenzoic Acid for Drug Nanosensor Application

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1311-1318页

作者： wong Yeong Yi F l Supian A Radzwan M Musa N F N Abd Karim Department of Physics Sultan Idris Education UniversityTanjong Malim 35900Malaysia Department of chemistry Sultan Idris Education UniversityTanjong Malim 35900Malaysia

calix[n]arenes was utilized to detect PABA,the primary sunscreen *** study investigates the interaction of calix[4]arene(c4),calix[6]arene(c6),and PABA using the langmuir method and first-principle density functional theory(DFT).Using the langmuir-Schaefer(lS)technique,an ultrathin film composed of calix[n]arenes and their complexes with PABA was deposited on various *** on the langmuir study,the PABA molecule was bonded to the lower rims of both c4 and c6 with the host-guest ratio of 1:*** of the lS films formed were then characterized by ultravioletvisible spectroscopy(UV-Vis),Fourier-transform infrared spectroscopy(FTIR)and carbon,hydrogen,nitrogen,sulfur elemental analyzer(cHNS).The band gap reduction obtained in the DFT study denotes the charge transfer interaction with promising reactivity between the calix[n]arenes and *** sensing of PABA by c4 and c6 is successful based on the formation of bonding between them due to the hosts’effective trapping *** outcomes of this study could be applied to drug delivery systems for future pharmaceutical and medical applications.

关键词： calix[n]arenes band gap density functional theory langmuir-Schaefer PABA sensor

Synthetic brochosomes:Design,synthesis,and applications

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Nano Research 2024年第2期17卷 734-742页

作者： lin Wang Jinsol choi Tak-Sing wong Department of Mechanical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA

Brochosomes,which are nanoscopic buckyball-shaped granules produced by leafhoppers,are one of the most intricate structures discovered in *** functions of brochosomes have been proposed but only a few have been experimentally validated due to the challenge of fabricating their synthetic *** in micro-and nanofabrication have recently led to the emergence of synthetic brochosomes,opening up new possibilities for innovative *** review explores the early discovery of natural brochosomes and their geometrical features,followed by the recent progress in fabricating synthetic brochosomes and their *** on future applications and challenges in the scalable manufacturing of synthetic brochosomes are discussed.

关键词： synthetic brochosomes leafhopper antireflection superhydrophobicity surface-enhanced Raman scattering photocatalyst energy harvesting

Effect of radiative loss mechanisms on FIR thermometric parameters of Nd^(3+)-doped lithium tellurite glasses

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Journal of Rare Earths 2024年第7期42卷 1250-1257,I0002页

作者： c.Y.Morassuti A.P.l Silva l.A.O.Nunes S.M.lima l.H.c.Andrade Optical and Photothermal Spectroscopy Group(GEOF) Center for Studies in Natural Resources(CERNA)State University of Mato Grosso do Sul(UEMS)C.P.351DouradosMSBrazil Renato Archer Information Technology center Dom Pedro I Highway(SP-65)Km 1436-Chácaras Campos dos AmaraisCampinasSPBrazil Institute of Physics of São carlos University of São PauloSão CarlosSPBrazil

Nd^(3+)-doped tellurite glasses are promising materials for thermometers based on the fluorescence intensity ratio(FIR)***,at high Nd^(3+)concentrations,energy transfer(ET)processes such as optical reabsorption and cross-relaxation can affect the Nd^(3+)emission,which has been little explored in the ***,the present work investigated the use of Nd^(3+)-doped tellurite glass(samples doped with Nd^(3+)at 0.2 mol%,0.5 mol%,2.0 mol%,and 4.0 mol%)in fluorescence thermometers,in the temperature range from 299 to 371 *** results indicate a strong dependence of the FIR parameters on the Nd^(3+)concentration,due to changes in the emission band profiles caused by optical reabsorption of the Nd^(3+)emissions and cross-relaxation processes.A decrease of the relative sensitivity of the ratio^(4)F_(5/2)→^(4)I_(9/2)/^(4)F_(3/2)→^(4)I_(9/2)is observed for samples doped with higher amounts of Nd^(3+).The maximum relative sensitivity at 299 K is 3.00%/K,which is the highest value among the reported Nd^(3+)ions.

关键词： Nd^(3+)-doped tellurite glass Fluorescence intensity ratio Optical thermometry Judd-Ofelt Rare earths

Nonaqueous potassium-ion full-cells:Mapping the progress and identifying missing puzzle pieces

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Journal of Energy chemistry 2024年第6期93卷 384-399,I0010页

作者： Badre larhrib louiza larbi lénaïc Madec Universite de Pau et des Pays de l’Adour E2S UPPACNRSIPREMPauFrance Universitéde Haute-Alsace Institut de Science des Matériaux de Mulhouse(IS2M)CNRS UMR 7361F-68100 MulhouseFrance Universitéde Strasbourg F-67081 StrasbourgFrance Réseau sur le Stockage Electrochimique de l’Energie CNRS FR3459AmiensFrance Institut des Matériaux Jean Rouxel(IMN) CNRS UMR 6502Univ.Nantes44322 Cedex 3 NantesFrance

This review addresses the growing interest for potassium-ion full-cells(KIFcs)in view of the transition from potassium-ion half-cells(KIHcs)toward commercial K-ion batteries(KIBs).It focuses on the key parameters of KIFcs such as the electrode/electrolyte interfaces challenge,major barriers,and recent advancements in *** strategies for enhancing KIFc performance,including interfaces co ntrol,electrolyte optimization,electrodes capacity ratio,electrode material screening and electrode design,are *** review highlights the need to evaluate KIBs in full-cell configurations as half-cell results are strongly impacted by the K metal *** also emphasizes the importance of understanding solid electrolyte interphase(SEI)formation in KIFcs and explores promising nonaqueous as well as quasiand all-solid-state electrolytes *** review thus paves the way for practical,cost-effective,and scalable KIBs as energy storage systems by offering insights and guidance for future research.

关键词： K-ion full-cells Potassium-ion batteries cross-talk Solid-state batteries Potassium reactivity Electrolyte design Electrode design