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Effects of Weaving Laser on Weld Microstructure and crack for Al 6k21-T4 Alloy

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Journal of Materials Science & Technology 2011年第1期27卷 93-96页

作者： B.h.kim N.h.Kang W.T.Oh c.h.kim J.h.kim Y.S.kim Y.h.Park Department of Materials Science and Engineering Pusan National UniversitySan30Jangjeon-dongGeumjeong-guBusan 609-735Korea Department of Materials and components Engineering Dong-Eui UniversityBusan 614-714Korea Advanced Joining Technology Team KITECH7-47Songdo-dongYeonsu-guIncheon 406-840Korea Division for Dongnam Area Technology Service KITECHJisa-dongGanseo-guBusan 618-230Korea

For Al 6k21-T4 overlap weld joint,the shear-tensile strength by using the weaving laser was improved as compared to the case of linear *** the specimen of low strength,the porosity was distributed continuously along the intersection between the plates and fusion ***,for the optimized welding condition,large oval-shaped porosities were located only in the advancing track of the concave ***,the continuity of cracks and porosities played a key role to determine the ***,the weaving width was also the important parameter to control the ***,the concave part had more significant hot and cold cracking in the weld and heat-affected zone（hAZ）,respectively,than the convex part.

关键词： Weaving laser Weld microstructure Void Al alloy

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关于回火马氏体脆性的新见解

兵器材料科学与工程 1987年第6期 71-73页

作者： h.Kwon c.h.kim 史洪刚

马氏体钢在250℃～450℃温度范围内回火后不但强度降低,韧性也降低。这种现象被称为回火马氏体脆性(TME)。一般认为,TME是晶界上杂质和碳化物联合作用引起的晶间脆性断裂,但由板条间(或板条内)碳化物引起的穿晶脆性型TME也见于报导。人... 详细信息

马氏体钢在250℃～450℃温度范围内回火后不但强度降低,韧性也降低。这种现象被称为回火马氏体脆性(TME)。一般认为,TME是晶界上杂质和碳化物联合作用引起的晶间脆性断裂,但由板条间(或板条内)碳化物引起的穿晶脆性型TME也见于报导。人们研究TME多从显微组织

关键词：脆性断裂穿晶合金元素碳化物碳化合物马氏体钢耐热钢

Machine learning empowers efficient design of ternary organic solar cells with PM6 donor

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Journal of Energy chemistry 2025年第1期100卷 337-347页

作者： Kiran A.Nirmal Tukaram D.Dongale Santosh S.Sutar Atul c.Khot Tae Geun kim School of Electrical Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoulRepublic of Korea computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India Yashwantrao chavan School of Rural Development Shivaji UniversityKolhapur 416004India

Organic solar cells(OScs) hold great potential as a photovoltaic technology for practical ***, the traditional experimental trial-and-error method for designing and engineering OScs can be complex, expensive, and time-consuming. Machine learning(ML) techniques enable the proficient extraction of information from datasets, allowing the development of realistic models that are capable of predicting the efficacy of materials with commendable accuracy. The PM6 donor has great potential for high-performance OScs. however, it is crucial for the rational design of a ternary blend to accurately forecast the power conversion efficiency(PcE) of ternary OScs(TOScs) based on a PM6 ***, we collected the device parameters of PM6-based TOScs and evaluated the feature importance of their molecule descriptors to develop predictive models. In this study, we used five different ML algorithms for analysis and prediction. For the analysis, the classification and regression tree provided different rules, heuristics, and patterns from the heterogeneous dataset. The random forest algorithm outperforms other prediction ML algorithms in predicting the output performance of PM6-based TOScs. Finally, we validated the ML outcomes by fabricating PM6-based TOScs. Our study presents a rapid strategy for assessing a high PcE while elucidating the substantial influence of diverse descriptors.

关键词： Machine learning Ternary organic solarcells PM6 donor PcE

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons

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Neural Regeneration Research 2025年第7期20卷 1999-2000页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(cleveland and Rothstein,2001).Frontotemporal lobar degeneration(FTLD)is a neurodegenerative disease affecting the frontal and temporal lobes of the brain,leading to changes in behavior,personality,and language(Van Langenhove et al.,2012).Both ALS and FTLD are classified as proteinopathies in which abnormal protein aggregation and accumulation in neurons contribute to the disease *** in sarcoma(FUS)is a DNA/RNA-binding protein involved in various cellular processes,including transcriptional regulation,RNA splicing,and DNA *** in the FUS gene have been linked to familial ALS,highlighting the importance of FUS in the disease pathogenesis(Vance et al.,2009).In ALS and FTLD,aberrant post-translational modifications(PTMs)of FUS,such as phosphorylation,acetylation,and methylation,have been implicated in the promotion of FUS aggregation and neurotoxicity(choi et al.,2023).Therefore,understanding the regulatory mechanisms of FUS PTMs is crucial for developing targeted therapies against these diseases.

关键词： degeneration FUS aggregation

carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第8期20卷 2319-2320页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS),also known as Lou Geh rig's disease,is a progressive neurodegenerative disorder that affects motor neurons in the brain and spinal *** leads to muscle weakness,paralysis,and ultimate... 详细信息

关键词： paralysis sclerosis respiratory

Recovery of the injured neural system through gene delivery to surviving neurons in Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： chanchal Sharma Sehwan kim hyemi Eo Sang Ryong kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

Plant cell Wall-Like Soft Materials:Micro-and Nanoengineering,Properties,and Applications

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Nano-Micro Letters 2025年第5期17卷 37-77页

作者： Roya Koshani Mica L.Pitcher Jingyi Yu christine L.Mahajan Seong h.kim Amir Sheikhi Department of chemical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of chemistry The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biology The Pennsylvania State UniversityUniversity ParkPA 16802USA Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA huck Institutes of the Life Sciences The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Neurosurgery College of MedicineThe Pennsylvania State UniversityHersheyPA 17033USA

Plant cell wall(cW)-like soft materials,referred to as artificial cWs,are composites of assembled polymers containing micro-/nanoparticles or fibers/fibrils that are designed to mimic the composition,structure,and mechanics of plant ***-like materials have recently emerged to test hypotheses pertaining to the intricate structure–property relationships of native plant cWs or to fabricate functional ***,research on plant cWs and cW-like materials is reviewed by distilling key studies on biomimetic composites primarily composed of plant polysaccharides,including cellulose,pectin,and hemicellulose,as well as organic polymers like ***-and nanofabrication of plant cW-like composites,characterization techniques,and in silico studies are reviewed,with a brief overview of current and potential ***-/nanofabrication approaches include bacterial growth and impregnation,layer-by-layer assembly,film casting,3-dimensional templating microcapsules,and particle *** characterization techniques are necessary for the comprehensive mechanical,chemical,morphological,and structural analyses of plant cWs and cW-like ***-like materials demonstrate versatility in real-life applications,including biomass conversion,pulp and paper,food science,construction,catalysis,and reaction *** review seeks to facilitate the rational design and thorough characterization of plant cW-mimetic materials,with the goal of advancing the development of innovative soft materials and elucidating the complex structure–property relationships inherent in native cWs.

关键词： Synthetic plants Biomimicry Acellular wall composites Living materials Soft matter

Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram D.Dongale Atul c.Khot chenjie Yao Nahyun kim Tae Geun kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

high mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

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Neural Regeneration Research 2025年第1期20卷 107-115页

作者： hanki kim Bum Jun kim Seungyon Koh hyo Jin cho Xuelian Jin Byung Gon kim Jun Young choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

high-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration