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Machine learning guided discovery of ternary compounds involving La and immiscible co and Pb elements

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npj computational Materials 2022年第1期8卷 2462-2470页

作者： Renhai Wang Weiyi Xia Tyler JSlade Xinyu Fan Huafeng Dong Kai-Ming Ho Paul c.canfield cai-Zhuang Wang School of Physics and Optoelectronic Engineering Guangdong University of Technology510006GuangzhouChina Department of Physics and Astronomy Iowa State UniversityAmesIA50011USA ames Laboratory-USDOE Iowa State UniversityAmesIA50011USA Department of Physics University of Science and Technology of China230026HefeiChina

Ternary compounds with an immiscible pair of elements are relatively unexplored but promising for novel quantum materials *** what third element and its ratio that can be added to make stable ternary compounds out of an immiscible pair of elements remains a great *** this work,we combine a machine learning(ML)method with ab initio calculations to efficiently search for the energetically favorable ternary La-co-Pb compounds containing immiscible elements co and *** previously reported structures are correctly captured by our ***,we predict a ground state La_(3)coPb compound and 57 low-energy La-co-Pb ternary *** to synthesize La_(3)coPb via multiple techniques produce mixed or multi-phases samples with,at best,ambiguous signals of the predicted lowest-energy La_(3)coPb and the second lowest-energy La_(18)co_(28)Pb_(3)*** calculated results of gibbs free energy are consistent with experiments,and will provide very useful guidance for further experimental synthesis.

关键词： elements immiscible ternary

What to Eat:Evidence for Selective Autophagy in Plants

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Journal of Integrative Plant Biology 2012年第11期54卷 907-920页

作者： Brice E.Floyd Stephanie c.Morriss gustavo c.MacIntosh Diane c.Bassham Department of genetics Development and Cell BiologyIowa State UniversityAmes IA 50011USA Department of Biochemistry Biophysics and Molecular BiologyIowa State UniversityAmes IAUSA

Autophagy is a macromolecular degradation pathway by which cells recycle their contents as a developmental process, housekeeping mechanism, and response to environmental stress. In plants, autophagy involves the sequestration of cargo to be degraded, transport to the cell vacuole in a doublemembrane bound autophagosome, and subsequent degradation by lytic enzymes.

关键词： Autophagy degradation stress vacuole.

Search for two-neutrino double-beta decay of^(136)Xe to the 0^(+)_(1)excited state of 136Ba with the complete EXO-200 dataset

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chinese Physics c 2023年第10期47卷 1-9页

作者： S.Al Kharusi g.Anton I.Badhrees P.S.Barbeau D.Beck V.Belov T.Bhatta M.Breidenbach T.Brunner g.F.cao W.R.cen c.chambers B.cleveland M.coon A.craycraft T.Daniels L.Darroch S.J.Daugherty J.Davis S.Delaquis A.Der Mesrobian-Kabakian R.DeVoe J.Dilling A.Dolgolenko M.J.Dolinski J.Echevers W.Fairbank Jr. D.Fairbank J.Farine S.Feyzbakhsh P.Fierlinger Y.S.Fu D.Fudenberg P.gautam R.gornea g.gratta c.Hall E.V.Hansen J.Hoessl P.Hufschmidt M.Hughes A.Iverson A.Jamil c.Jessiman M.J.Jewell A.Johnson A.Karelin L.J.Kaufman T.Koffas R.Krücken A.Kuchenkov K.S.Kumar Y.Lan A.Larson B.g.Lenardo D.S.Leonard g.S.Li S.Li Z.Li c.Licciardi Y.H.Lin R.MacLellan T.McElroy T.Michel B.Mong D.c.Moore K.Murray O.Njoya O.Nusair A.Odian I.Ostrovskiy A.Perna A.Piepke A.Pocar F.Retière A.L.Robinson P.c.Rowson J.Runge S.Schmidt D.Sinclair K.Skarpaas A.K.Soma V.Stekhanov M.Tarka S.Thibado J.Todd T.Tolba T.I.Totev R.Tsang B.Veenstra V.Veeraraghavan P.Vogel J.-L.Vuilleumier M.Wagenpfeil J.Watkins M.Weber L.J.Wen U.Wichoski g.Wrede S.X.Wu Q.Xia D.R.Yahne L.Yang Y.-R.Yen O.Ya.Zeldovich T.Ziegler 无 Physics Department McGill UniversityMontrealQuebec H3A 2T8Canada Erlangen centre for Astroparticle Physics(EcAP) Friedrich-Alexander-University Erlangen-NürnbergErlangen 91058Germany Physics Department Carleton UniversityOttawaOntario K1S 5B6Canada Department of Physics Duke Universityand Triangle Universities Nuclear Laboratory(TUNL)DurhamNorth Carolina 27708USA Physics Department University of IllinoisUrbana-ChampaignIllinois 61801USA Institute for Theoretical and Experimental Physics named by A.I.Alikhanov of National Research centre“Kurchatov Institute” Moscow 117218Russia Department of Physics University of South DakotaVermillionSouth Dakota 57069USA SLAc National Accelerator Laboratory Menlo ParkCalifornia 94025USA TRIUMF VancouverBritish Columbia V6T 2A3Canada Institute of High Energy Physics Beijing 100049China Department of Physics Laurentian UniversitySudburyOntario P3E 2C6Canada Physics Department Colorado State UniversityFort CollinsColorado 80523USA Department of Physics and Physical Oceanography University of North Carolina at WilmingtonWilmingtonNC 28403USA Physics Department and cEEM Indiana UniversityBloomingtonIndiana 47405USA Physics Department Stanford UniversityStanfordCalifornia 94305USA Department of Physics Drexel UniversityPhiladelphiaPennsylvania 19104USA Amherst center for Fundamental Interactions and Physics Department University of MassachusettsAmherstMA 01003USA Technische Universität München Physikdepartment and Excellence Cluster UniverseGarching 80805Germany Physics Department University of MarylandCollege ParkMaryland 20742USA Department of Physics and Astronomy University of AlabamaTuscaloosaAlabama 35487USA Wright Laboratory Department of PhysicsYale UniversityNew HavenConnecticut 06511USA IBS center for Underground Physics Daejeon 34126Korea Department of Physics and Astronomy Stony Brook UniversitySUNYStony BrookNew York 11794USA Kellogg Lab CaltechPasadenaCalifornia 91125USA LHEP Albert Einstein CenterUniversi

A new search for two-neutrino double-beta(2νββ)decay of^(136)Xe to the 0+1 excited state of 136Ba is performed with the full EXO-200 dataset.A deep learning-based convolutional neural network is used to discriminate signal from bac.g.ound *** detection efficiency is increased relative to previous searches by EXO-200 by more than a factor of *** the addition of the Phase II dataset taken with an upgraded detector,the median 90%confidence level half-life sensitivity of 2νββdecay to the 0+1 state of 136Ba is 2.9×10^(24)yr using a total^(136)Xe exposure of 234.1 kg *** statistically significant evidence for 2νββdecay to the 0^(+)_(1)state is observed,leading to a lower limit of T2ν1/2(0^(+)→0^(+)_(1))>1.4×10^(24)yr at 90%confidence level,improved by 70%relative to the current world's best constraint.

关键词： EXO-200 experiment neutrinoless double beta decay excited state

Transcytosis of Junonia coenia densovirus VP4 across the gut epithelium of Spodoptera frugiperda(Lepidoptera:Noctuidae)

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Insect Science 2020年第1期27卷 22-32页

作者： Mariah Kemmerer Bryony c.Bonning Department of Entomology Iowa State UniversityAmesIowaUSA Department of Entomology and Nematology University of FloridaGainesvilleFloridaUSA

The Junonia coenia densovirus rapidly traverses the gut epithelium of the host lepidopteran without replicating in the gut *** ability of this virus to transcytose across the gut epithelium is of interest for the potential use of virus structural proteins as delivery vehicles for insecticidal peptides that act within the insect hemocoel,rather than in the *** this study,we used fall armyworm,Spodoptera frugiperda to examine the binding of the virus to brush border membrane vesicle proteins by two-dimensional ligand blot *** also assessed the rate of flux of the primary viral structural protein,VP4 fused to egFP with a proline-rich linker(VP4-P-egFP)through the gut epithelium ex vivo in an Ussing *** mechanisms involved with transcytosis of VP4-P-egFP were assessed by use of *** serum albumin(BSA)and egFP were used as positive and negative control proteins,*** contrast to BSA,which binds to multiple proteins on the brush border membrane,VP4-P-egFP binding was specific to a protein of high molecular *** flux was significantly higher for VP4-P-egFP after 2 h than for albumin or egFP,with rapid transcytosis of VP4-P-egFP within the first 30 *** contrast to BSA which transcytosed following clathrin-mediated endocytosis,the movement of VP4-P-egFP was vesicle-mediated but *** specificity of binding combined with the efficiency of transport across the gut epithelium suggest that VP4 will provide a useful carrier for insecticidal peptides active within the hemocoel of key lepidopteran pests including ***.

关键词： BSA gut epithelium JcDNV Lepidoptera transcytosis virus

Ultrafast Martensitic Phase Transition Driven by Intense Terahertz Pulses

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Ultrafast Science 2023年第1期3卷 27-32页

作者： B.Q.Song X.Yang c.Sundahi J-H.Kang M.Mootz Y.Yao I.E.Perakis L.Luo c.B.Eom J.Wang Department of Physics and Astronomy lowa State UniversityAmesIA 50011USA ames National Laboratory of U.S.DOE AmesIA 50011USA Department of Materials Science and Engineering.University of Wisconsin-Madison MadisonWI 53706USA Department of Physics University of Alabama at BirminghamBirminghamAL35294-1170USA

We report on an ultrafast nonequilibrium phase transition with a strikingly long-lived martensitic anomaly driven by above-threshold single-cycle terahertz pulses with a peak field of more than 1 MV/cm.A nonthermal,terahertz-induced depletion of low-frequency conductivity in Nb_(3)Sn indicates increased gap splitting of high-energy Г_(12) bands by removal of their degeneracies,which induces the martensitic phase above their equilibrium transition *** contrast,optical pumping leads to a Г_(12) gap thermal *** light-induced nonequilibrium martensitic phase exhibits a substantially enhanced critical temperature up to~100 K,i.e.,more than twice the equilibrium temperature,and can be stabilized beyond technologically relevant,nanosecond time *** with first-principle simulations,we identify a compelling terahertz tuning mechanism of structural order via Г_(12) phonons to achieve the ultrafast phase transition to a metastable electronic state out of equilibrium at high temperatures far exceeding those for equilibrium states.

关键词： martensitic equilibrium nonequilibrium

genome–Phenome Wide Association in Maize and Arabidopsis Identifies a common Molecular and Evolutionary Signature

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Molecular Plant 2020年第6期13卷 907-922页

作者： Zhikai Liang Yumou Qiu James c.Schnable Department of Agronomy and Horticulture University of Nebraska-LincolnLincolnNEUSA Plant Science Innovation center University of Nebraska-LincolnLincolnNEUSA Department of Statistics Iowa State UniversityAmesIAUSA

Linking natural genetic variation to trait variation can help determine the functional roles ofdifferent *** of one or several traits are often assessed ***-throughput phenotyping and data mining can capture dozens or hundreds of traits from the same ***,we test the association between markers within a gene and many traits *** genome–phenome wide association study(gPWAS)is both a multi-marker and multi-trait *** identified using gPWAS with 260 phenotypic traits in maize were enriched for genes independently linked to phenotypic *** associated with classical mutants were consistent with reported phenotypes for mutant *** linked to phenomic variation in maize using gPWAS shared molecular,population genetic,and evolutionary features with classical mutants in *** linked to phenomic variation in Arabidopsis using gPWAS are significantly enriched in genes with known loss-of-function *** may be an effective strategy to identify genes in which loss-of-function alleles produce mutant *** shared signatures present in classical mutants and genes identified using gPWAS may be markers for genes with a role in specifying plant phenotypes generally or pleiotropy specifically.

关键词： quantitative genetics phenomics genome-wide association studies mutant phenotypes maize Arabidopsis

The Dicistroviridae: An Emerging Family of Invertebrate Viruses

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Virologica Sinica 2009年第5期24卷 415-427页

作者： Bryony c. Bonning Department of Entomology Iowa State University 418 Science Ⅱ Ames IA 50011-3222 USA

Dicistroviruses comprise a newly characterized and rapidly expanding family of small RNA viruses of invertebrates. Several features of this virus group have attracted considerable research interest in recent years. In this review I provide an overview of the Dicistroviridae and describe progress made toward the understanding and practical application of dicistroviruses, including (i) construction of the first infectious clone of a dicistrovirus, (ii) use of the baculovirus expression system for production of an infectious dicistrovirus, (iii) the use of Drosophila c virus for analysis of host response to virus infection, and (iv) correlation of the presence of Israeli acute paralysis virus with honey bee colony collapse disorder. The potential use of dicistroviruses for insect pest management is also discussed. The structure, mechanism and practical use of the internal ribosome entry site (IRES) elements has recently been reviewed elsewhere.

关键词：无脊椎动物动物病毒家族杆状病毒表达系统小RNA病毒感染性克隆病毒感染丙肝病毒

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活着的中国哲学

孔学堂 2015年第1期2卷 78-84,215,216,217,218,219,220,221,222,223页

作者：安乐哲美国夏威夷大学哲学系教授美国夏威夷96822

本文标题"活着的中国哲学"具有双重含义。一方面,说明中国哲学可以让研究者发生转变;另一方面,也揭示出中国哲学的传统——把日常事务当作哲学思考的源泉和得出结论的保证。文本典籍不仅提供思考哲学问题所需的词汇,更重要的是鼓励个人... 详细信息

本文标题"活着的中国哲学"具有双重含义。一方面,说明中国哲学可以让研究者发生转变;另一方面,也揭示出中国哲学的传统——把日常事务当作哲学思考的源泉和得出结论的保证。文本典籍不仅提供思考哲学问题所需的词汇,更重要的是鼓励个人修身养性,让人生变得有意义,化平凡为神奇。

关键词：儒学比较哲学角色伦理罗思文郝大维刘殿爵非西方哲学过程哲学

In vitro toxicity of particulate matter emissions from residential pellet combustion

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Journal of Environmental Sciences 2022年第5期34卷 215-226页

作者： Estela D.Vicente Daniela Figueiredo catia goncalves Isabel Lopes Helena Oliveira Nora Kovats Teresa Pinheiro celia A.Alves Department of Environment and Planning and cESAM-centre for Environmental and Marine Studies University of Aveiro3810-193 AveiroPortugal Department of Biology and cESAM-centre for Environmental and Marine Studies University of Aveiro3810-193 AveiroPortugal centre of Natural Environmental Sciences University of PannoniaEgyetem str.108200 VeszpremHungary Instituto de Bioengenharia e Biociencias Departamento de Engenharia e Ciencias NuclearesInstituto Superior TecnicoUniversidade de LisboaAv.Rovisco Pais 11049-001 LisboaPortugal

Particulate matter emissions(PM10)from the combustion,in a residential stove,of two com-mercial brands of certified(ENplus A1)pellets,a non-certified brand and laboratory made pellets of acacia were tested for their ability to induce ecotoxic,cytotoxic,and mutagenic re-sponses in unicellular organisms and a human cell *** was evaluated through the Vibrio fischeri bioluminescence inhibition ***,cytotoxicity was assessed at two time points(24-and 48-hr)through two complementary techniques in order to evaluate the cellular metabolic activity and membrane integrity of human lung epithelial cells *** ames test using two Salmonella typhimurium strains(TA100 and TA98)was employed to assess the mutagenic potential of the polycyclic aromatic hydrocarbon fraction extracted from the PM10 *** obtained with the bioluminescent bacteria indicated that only particles from the combustion of acacia pellets were *** samples induced im-pairment on the A549 cells metabolic activity,while no significant release of lactate dehy-drogenase was ***10 emissions from acacia pellets were the most cytotoxic,while samples from both certified pellets evoked significant cytotoxicity at lower ***-icity time-dependency was only observed for PM10 from the combustion of acacia pellets and one of the brands of certified *** activity was not detected in both *** murium *** study emphasises the role of the raw material for pellet manu-facturing on the toxicological profile of PM *** raw materials should be deeply investigated before their use in pelletisation and combustion in residential appli-ances.

关键词： Ecotoxicity cytotoxicity Mutagenicity Fuel quality Pellet combustion PM10 emissions