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Mid-term clinical outcomes of the uncemented robert Mathys pressfit cup

World Journal of clinical cases 2024年第19期12卷 3684-3691页

作者： Kishan ritek ramsodit Inger N Sierevelt Esther r c Janssen Sjoerd Kaarsemaker Daniël Haverkamp Department of Orthopedic Surgery Xpert Clinics AmsterdamAmsterdam 1101EANorth-HollandNetherlands Department of Orthopedic Spaarne Gasthuis AcademyHoofddorp 2134 TMNetherlands Department of Orthopaedic Surgery Viecuri Medical CentreVenlo 5912 BLNetherlands Department of Orthopaedic Surgery Viecuri Medisch CentrumVenlo 5912 BLNetherlands

BAcKGrOUND The use of uncemented cups during total hip arthroplasty(THA)has gained popularity in recent *** robert Mathys(rM)pressfit cup,an uncemented monoblock implant is expected to preserve bone density due to its composition and external surface,while reducing backside wear with its monoblock *** factors should lead to a high survival rate of the *** To evaluate the mid-term survival and functional outcome of the rM Pressfit cup in a large study *** Between 2011 and 2020,we included 1324 patients receiving a primary THA using the rM pressfit *** clinical follow-up was performed at 2 years postoperatively with the Dutch arthroplasty register used to assess implant status *** for acetabular failure and reason for revision were reported to evaluate implant survival,while the hip disability and osteoarthritis outcome score(HOOS)scores were used to assess functional *** The mean age at surgery was 64.9 *** mean follow-up was 4.6 *** the 1324 THAs performed,13 needed cup revisions within 5 years after index THA:5 due to aseptic loosening,6 due to infection,2 due to dislocation and 2 due to other *** resulted in a 5-year cup survival of 98.8%(95%cI:98.1-99.5).Nine of the cup revisions occurred within the first year after index *** scores increased significantly in all domains during the first year and levelled out during the second *** In the present study,the rM pressfit cup demonstrated excellent clinical outcomes at mid-term follow-up;however,future studies are needed to assess the long-term outcomes of this acetabular implant.

关键词： Total hip arthroplasty Uncemented rM pressfit cup Hip osteoarthritis cup revision Pressfit Aseptic loosening

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A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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Bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.Beeren G.Dos Santos P.J.Dijkstra c.Mota J.Bauer H.Ferreira rui l.reis N.Neves S.camarero-Espinosa M.B.Baker l.Moroni Department of complex Tissue regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal IcVS/3B’s-PT Government Associate laboratory 4806-909 Braga/GuimarãesPortugal POlYMAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKErBASQUE Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering ***,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface ***,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(Pcl5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight Pcl75k at different *** porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight Pcl *** a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morphogenetic protein 2(BMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMScs)was *** two weeks of culturing in a basic medium,cells expressed higher levels of BMP receptor II(BMPrII)on films with the conjugated *** addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface *** together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material ***,we have presented a viable strategy for ME-AM community that desires to tune the bulk and surface functionality via blending of(m

关键词： Additive manufacturing Blending Surface functionalization Surface density click chemistry Human

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STcF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.c.Ai l.P.An r.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.cai H.cai J.J.cao Q.H.cao X.cao Z.cao Q.chang K.T.chao D.Y.chen H.chen H.X.chen J.F.chen K.chen l.l.chen P.chen S.l.chen S.M.chen S.chen S.P.chen W.chen X.chen X.F.chen X.r.chen Y.chen Y.Q.chen H.Y.cheng J.cheng S.cheng T.G.cheng J.P.Dai l.Y.Dai X.c.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding l.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du l.M.Duan D.Epifanov Y.l.Fan S.S.Fang Z.J.Fang G.Fedotovich c.Q.Feng X.Feng Y.T.Feng J.l.Fu J.Gao Y.N.Gao P.S.Ge c.Q.Geng l.S.Geng A.Gilman l.Gong T.Gong B.Gou W.Gradl J.l.Gu A.Guevara l.c.Gui A.Q.Guo F.K.Guo J.c.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.l.Han l.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.l.He Z.B.He Z.X.Heng B.l.Hou T.J.Hou Y.r.Hou c.Y.Hu H.M.Hu K.Hu r.J.Hu W.H.Hu X.H.Hu Y.c.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.l.Kang X.S.Kang B.c.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.lei E.levichev c.H.li c.li D.Y.li F.li G.li G.li H.B.li H.li H.N.li H.J.li H.l.li J.M.li J.li l.li l.li l.Y.li N.li P.r.li r.H.li S.li T.li W.J.li X.li X.H.li X.Q.li X.H.li Y.li Y.Y.li Z.J.li H.liang J.H.liang Y.T.liang G.r.liao l.Z.liao Y.liao c.X.lin D.X.lin X.S.lin B.J.liu c.W.liu D.liu F.liu G.M.liu H.B.liu J.liu J.J.liu J.B.liu K.liu K.Y.liu K.liu l.liu Q.liu S.B.liu T.liu X.liu Y.W.liu Y.liu Y.l.liu Z.Q.liu Z.Y.liu Z.W.liu I.logashenko Y.long c.G.lu J.X.lu N.lu Q.F.lü Y.lu Y.lu Z.lu P.lukin F.J.luo T.luo X.F.luo Y.H.luo H.J.lyu X.r.lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng r.Mitchell A.Nefediev Y.Nefedov S.l.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng l.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian c.F.Qiao J.J.Qin J.J.Qin l.Q.Qin X.S.Qin T.l.Qiu J.rademacker c.F.redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia cAS Key laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China cavendish laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom central china Normal University Wuhan 430079China central South University Changsha 410083China china University of Geosciences Wuhan 430074China china University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de lausanne(EPFl) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STcF)is an electron–positron collider proposed by the chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STcF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPcII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STcF project in china is under development with an extensive r&D *** document presents the physics opportunities at the STcF,describes conceptual designs of the STcF detector system,and discusses future plans for detector r&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STcF detector conceptual design

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Blood metal concentrations and cardiac structure and function in total joint arthroplasty patients

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World Journal of Orthopedics 2024年第8期15卷 773-782页

作者： Peter c Brennan Stephanie M Peterson Thomas J O'Byrne Mariana l laporta cody c Wyles Paul J Jannetto Garvan c Kane Maria Vassilaki Hilal Maradit Kremers Department of Orthopedic Surgery Mayo ClinicRochesterMN 55905United States Department of Quantitative Health Sciences Mayo ClinicRochesterMN 55905United States Department of Anesthesiology and Perioperative Medicine Mayo ClinicRochesterMN 55905United States Department of laboratory Medicine and Pathology Mayo ClinicRochesterMN 55905United States Department of cardiovascular Diseases Mayo ClinicRochesterMN 55905United States

BAcKGrOUND There is concern regarding potential long-term cardiotoxicity with systemic distribution of metals in total joint arthroplasty(TJA)*** To determine the association of commonly used implant metals with echocardiographic measures in TJA *** The study comprised 110 TJA patients who had a recent history of high chromium,cobalt or titanium *** underwent two-dimensional,three-dimensional,Doppler and speckle-strain transthoracic echocardiography and a blood draw to measure metal *** and sex-adjusted linear and logistic regression models were used to examine the association of metal concentrations(exposure)with echocardiographic measures(outcome).rESUlTS Higher cobalt concentrations were associated with increased left ventricular end-diastolic volume(estimate 5.09;95%cI:0.02-10.17)as well as left atrial and right ventricular dilation,particularly in men but no changes in cardiac *** titanium concentrations were associated with a reduction in left ventricle global longitudinal strain(estimate 0.38;95%cI:0.70 to 0.06)and cardiac index(estimate 0.08;95%cI,-0.15 to-0.01).cONclUSION Elevated cobalt and titanium concentrations may be associated with structural and functional cardiac changes in some *** studies are warranted to better understand the systemic effects of metals in TJA patients.

关键词： Total joint arthroplasty Metal-on-metal cardiotoxicity Heart failure Echocardiography cobalt

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2024 Adult compendium of Physical Activities:A third update of the energy costs of human activities

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Journal of Sport and Health Science 2024年第1期13卷 6-12页

作者： Stephen D.Herrmann Erik A.Willis Barbara E.Ainsworth Tiago V.Barreira Mary Hastert chelsea l.Kracht John M.Schuna Jr. Zhenghui cai Minghui Quan catrine Tudor-locke Melicia c.Whitt-Glover David r. Jacobs Jr. Kansas center for Metabolism and Obesity research University of Kansas Medical CenterKansas CityKS 66160USA Division of Physical Activity and Weight Management Department of Internal MedicineUniversity of Kansas Medical CenterKansas CityKS 66160USA center for Health Promotion and Disease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA college of Health Solutions Arizona State UniversityPhoenixAZ 85003USA School of Exercise and Health Shanghai University of SportShanghai 200438China Exercise Science Department Syracuse UniversitySyracuseNY 13244USA clinical Sciences Division Pennington Biomedical Research CenterBaton RougeLA 70808USA School of Exercise and Sport Science Oregon State UniversityCorvallisOR 97331USA college of Health and Human Services University of North Carolina at CharlotteCharlotteNC 28223USA Gramercy research Group KnightdaleNC 27545USA Division of Epidemiology and community Health School of Public HealthUniversity of MinnesotaMinneapolisMN 55454USA

Background:The compendium of Physical Activities was published in 1993 to improve the comparability of energy expenditure values assigned to self-reported physical activity(PA)across *** original version was updated in 2000,and again in 2011,and has been widely used to support PA research,practice,and public health ***:This 2024 update was tailored for adults 19-59 years of age by removing data from those≥60 *** a systematic review and supplementary searches,we identified new activities and their associated measured metabolic equivalent(MET)values(using indirect calorimetry)published since *** replaced estimated METs with measured values when ***:We screened 32,173 abstracts and 1507 full-text papers and extracted 2356 PA energy expenditure values from 701 *** added303 new PAs and adjusted 176 existing MET values and descriptions to reflect the addition of new data and removal of METs for older *** added a Major Heading(Video Games).The 2024 Adult compendium includes 1114 PAs(912 with measured and 202 with estimated values)across 22 Major ***:This comprehensive update and refinement led to the creation of The 2024 Adult compendium,which has utility across research,public health,education,and healthcare domains,as well as in the development of consumer health *** new website with the complete lists of PAs and supporting resources is available at https://***.

关键词： Adults Energy expenditure Exercise MET Physical Activities

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Post-fire recovery of Puya raimondii, vegetation and birds in the puna of Huascarán National Park, Perú

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Journal of Mountain Science 2024年第1期21卷 20-32页

作者： Mery l.SUNI Giovana P.VADIllO césar ArANA Enoc JArA-PENA letty SAlINAS M.Estela PONcE Paul M.rAMSAY Plant Physiology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Natural History Museum Universidad Nacional Mayor de San MarcosLima 15072Peru Applied Phytology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of Statistics Faculty of Mathematical SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of chemical and Biological Sciences Universidad de las Américas PueblaSan Andrés Cholula CP Cholula CP 72810Mexico

A large fire of 233 ha in Huascarán National Park in Peru provided an opportunity to compare plant and bird responses in burned and nearby unburned zones of the puna. Heights and live diameters of flagship Puya raimondii rosettes(assigned to four broad developmental phases), plant communities(66 species in 24 families and nine growth forms) and bird communities(77 species in six trophic guilds) were monitored after the fire. Although no mortality was observed, Puya raimondii plants were affected by the fire, losing approximately 60% of their photosynthetic area across all developmental phases, but recovered quickly during the first two years after fire. The comparison of Puya rosette recovery after fire was complicated by the changes in live rosette diameter for unburned plants, which showed plasticity of photosynthetic area linked to seasonal and annual fluctuations in precipitation in this relatively dry environment(decreased by 26% for mature adult plants over the study period). Fire caused an immediate change in the density, biomass and composition of vegetation. Although the species present remained similar, their abundances changed significantly immediately after the fire, with notable reductions in dominant tussock grasses. This provided opportunities for other plants, resulting in higher postfire diversity of plant species, genera, families and growth forms. In turn, the changes in vegetation after fire affected the composition of birds according to their trophic guild. Granivores largely disappeared,generalists were mostly unaffected, and other guilds showed a more complex response. As the vegetation recovered, most displaced birds returned within approximately one year.

关键词： Burning Plant biomass Trophic guilds Andes Giant rosette plants

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Electrobiocorrosion by microbes without outer-surface cytochromes

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mlife 2024年第1期3卷 110-118页

作者： Dawn E.Holmes Trevor l.Woodard Jessica A.Smith Florin Musat Derek r.lovley Department of Microbiology University of Massachusetts AmherstAmherstMassachusettsUSA Department of Physical and Biological Science Western New England UniversitySpringfieldMassachusettsUSA Department of Biomolecular Sciences Central Connecticut State UniversityNew BritainConnecticutUSA Department of Biology Section for MicrobiologyAarhus UniversityAarhusDenmark Department of Molecular Biology and Biotechnology Facuity of Biology and GeologyBabes-Bolyai UniversityCluj-NapocaRomania

Anaerobic microbial corrosion of iron-containing metals causes extensive economic *** microbes are capable of direct metal-to-microbe electron transfer(electrobiocorrosion),but the prevalence of electrobiocorrosion among diverse methanogens and acetogens is poorly understood because of a lack of tools for their genetic *** studies have suggested that respiration with 316l stainless steel as the electron donor is indicative of electrobiocorrosion,because,unlike pure Fe^(0),316l stainless steel does not abiotically generate H_(2) as an intermediary electron ***,we report that all of the methanogens(Methanosarcina vacuolata,Methanothrix soehngenii,and Methanobacterium strain IM1)and acetogens(Sporomusa ovata and clostridium ljungdahli)evaluated respired with pure Fe^(0)as the electron donor,but only ***,***,and *** were capable of stainless steel *** electrobiocorrosive methanogens re-quired acetate as an additional energy source in order to produce methane from stainless *** of *** and *** demonstrated how acetogens can provide acetate to methanogens during *** only was Meth-anobacterium strain IM1 not capable of electrobiocorrosion,but it also did not accept electrons from Geobacter metal-lireducens,an effective electron-donating partner for direct interspecies electron transfer to all methanogens that can directly accept electrons from Fe^(0).The finding that ***,***,and *** are capable of electrobiocorrosion,despite a lack of the outer-surface c-type cytochromes previously found to be important in other electrobiocorrosive microbes,demonstrates that there are multiple microbial strategies for making electrical contact with Fe^(0).

关键词： acetogen corrosion Fe^(0) methanogen stainless steel

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Degradation and resynthesis of chlorophyll during increased oxidative stress and prolonged darkness differ between annual and perennial flax(linum l.)

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Oil crop Science 2024年第2期9卷 121-130页

作者： Kenyon J. Nisbett Abida Alokozai Su Hyun Elizabeth Ko G. Adam Mott Jason c.l. Browna Department of Biological Sciences University of Toronto ScarboroughTorontoONCanada Department of cell&Systems Biology University of TorontoTorontoONCanada centre for the Analysis of Genome Evolution&Function University of TorontoTorontoONCanada

Among plants,there is considerable variation in lifespan:annuals live less than one year,whereas perennials live for several years,with the longest-living perennial having survived 43,600 *** proposed by the Disposable Soma Theory,this lifespan variation among plants likely reflects differential investment of limited energy and nutrient resources,with perennials investing more energy and nutrients into biomolecular maintenance compared to annuals in order to ensure persistence over multiple *** differential investment may be particularly important during periods of exogenous stress,which are known to accelerate biomolecular *** present study evaluated this hypothesis using annual and perennial flax(linum l.)subjected to two exogenous stressors—increased oxidative stress(i.e.,foliar H2O2spraying)and complete prolonged *** chlorophyll has been shown to exhibit degradation in response to changes in environmental conditions,we utilized changes in chlorophyll levels during and after periods of exogenous stress to evaluate our *** predicted that i)perennials would exhibit a slower rate of chlorophyll degradation during exposure to exogenous stressors compared to annuals,and ii)perennials would exhibit a faster rate of chlorophyll resynthesis following such exposure compared to *** levels before,during,and after exposure to both exogenous stressors were measured in two separate trails,once using image colour analysis and once using *** chlorophyll degradation rates in response to oxidative stress did not differ between annuals and perennials,contrary to our predictions,chlorophyll resynthesis rates following such exposure were significantly higher in perennials,as *** plants were subjected to complete prolonged darkness,chlorophyll degradation rates were significantly lower in perennials than annuals,as predicted;however,when plants were subsequently reintroduced to natural photoperiod,ch

关键词： Ageing life history Maximum lifespan Oxidative stress Somatic maintenance

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Boosting Adaptive Weighted Broad learning System for Multi-label learning

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IEEE/cAA Journal of Automatica Sinica 2024年第11期11卷 2204-2219页

作者： Yuanxin lin Zhiwen Yu Kaixiang Yang Ziwei Fan c.l.Philip chen the School of computer Science and Engineering in South china University of Technology IEEE the Pengcheng laboratory

Multi-label classification is a challenging problem that has attracted significant attention from researchers, particularly in the domain of image and text attribute annotation. However, multi-label datasets are prone to serious intra-class and inter-class imbalance problems, which can significantly degrade the classification performance. To address the above issues, we propose the multi-label weighted broad learning system(MlW-BlS) from the perspective of label imbalance weighting and label correlation mining. Further, we propose the multi-label adaptive weighted broad learning system(MlAW-BlS) to adaptively adjust the specific weights and values of labels of MlW-BlS and construct an efficient imbalanced classifier set. Extensive experiments are conducted on various datasets to evaluate the effectiveness of the proposed model, and the results demonstrate its superiority over other advanced approaches.

关键词： Broad learning system label correlation mining label imbalance weighting multi-label imbalance

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A Practical Predefined-Time Stability criterion and Its Application to Uncertain Nonlinear Systems

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Journal of Systems Science & complexity 2024年

作者： XU Hao YU Dengxiu SUI Shuai XU Bowen cHEN c.l.Philip Unmanned System research Institute Northwestern Polytechnical University college of Science Liaoning University of Technology School of Artificial Intelligence Optics and Electronics Northwestern Polytechnical University School of computer Science and Engineering South China University of Technology and Pazhou Lab

In this paper, the singularity-free predefined-time fuzzy adaptive tracking control problem is studied for non-strict feedback(NSF) nonlinear systems considering mismatched external disturbances. An innovative practical predefined-time stability(PPTS) criterion is proposed to provide the theoretical basis for subsequent control design. compared to the existing predefined-time stability(PTS) criterion, this criterion has a broader application range and can solve the control design issues of nonlinear systems with system uncertainties. Fuzzy logic systems(FlSs) are employed to identify unknown nonlinear functions. Based on the backstepping control technology, a singularity-free predefined-time control(PTc) design method is proposed, in which the hyperbolic tangent function is utilized to avoid the singular problem, and the nature of fuzzy basis function is adopted to resolve the algebraic loop problem. The PPTS of the closed-loop NSF nonlinear system is proven with the lyapunov theory and the proposed PPTS criterion. Ultimately, the efficiency of the presented PTc design method is verified by several sets of simulations on a single link manipulator system.

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