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高频超声波内窥镜在喉病变诊断中的应用

山东大学基础医学院学报 2003年第1期17卷 45-47页

作者：李勇 c.arens 栾信庸潘新良许风雷王惠忠 H.Glanz 山东大学齐鲁医院耳鼻咽喉-头颈外科济南250012 德国Giessen大学医院耳鼻咽喉-头颈外科

目的 :研究高频超声波内窥镜图像技术在喉病变 ,特别是喉癌诊断中的应用。方法 :用可屈的小内径 (8-1 0F)高频 (1 0 -2 0MHz)内窥镜式超声探头 ,对 45例患者行喉腔内无创伤检查。在频率 1 0MHz最大探及 3cm ,在 2 0MHz最大探及 1 .5cm... 详细信息

目的 :研究高频超声波内窥镜图像技术在喉病变 ,特别是喉癌诊断中的应用。方法 :用可屈的小内径 (8-1 0F)高频 (1 0 -2 0MHz)内窥镜式超声探头 ,对 45例患者行喉腔内无创伤检查。在频率 1 0MHz最大探及 3cm ,在 2 0MHz最大探及 1 .5cm。超声图上 ,准确测量出肿瘤垂直直径大小及位置。结果 :其中探查到3 2例喉癌 ,与周围组织相比 ,呈现出典型的反射矩阵波。在显微喉镜检查中 ,借助高频超声可探查到T1 声带癌 (n=1 3 ) ,最小瘤体直径约 3mm的浸润癌。但 1 3例中有 6例探查不到肿瘤 (假阴性 ) ,假阳性结果尚未发现。T2 -T3喉癌 (n =1 2 )较易诊断 ,在声门上区和声门下区肿瘤较周围组织显示低回声区 ;T4 肿瘤 (n =7)侵犯甲状软骨可在超声图上较易显出 ,肿瘤的低回声区与甲状软骨内膜的高回声区有明显的反差 ;另外探及喉良性病变 1 3例。结论 :运用内窥镜式高频超声可在显微镜检查中对喉病变 ,特别是喉肿瘤的大小及相应浸润范围 ,做出更为准确的诊断。

关键词：高频超声波内窥镜喉病变喉癌诊断

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内窥镜在喉癌及其前期病变诊断中的应用

德国医学 2001年第5期18卷 306-307页

作者： c.arens K.Malzahn O.Dias M.Andrea H.Glanz 李勇王惠忠 Hals-Nasen-Ohrenklinik GieBen.Justus-Liebig-Universitat Feulgenstrafie 10 D-35385 GieBen Germany 山东齐鲁医院

自Kleinsasser(1962)首次将手术显微镜用于直达喉镜以来,显微喉镜得到了广泛发展应用,成为喉癌及其早期病变诊断和治疗的标准术式.显微喉镜可较准确的对喉粘膜的癌前病变及癌变进行早期诊断、治疗,在多数情况下喉粘膜得以恢复和保留,对... 详细信息

自Kleinsasser(1962)首次将手术显微镜用于直达喉镜以来,显微喉镜得到了广泛发展应用,成为喉癌及其早期病变诊断和治疗的标准术式.显微喉镜可较准确的对喉粘膜的癌前病变及癌变进行早期诊断、治疗,在多数情况下喉粘膜得以恢复和保留,对病人的生活质量影响不大.近年来在显微喉镜下切除喉内较大肿瘤作了一些尝试.基本来说,内窥镜手术能对粘膜上皮的早期病变及肿瘤的浸润程度作出较准确的术前诊断,从而尽可能的对其作局部性的治疗.

关键词：喉癌前期病变内窥镜诊断

Important step towards an understanding of the exotic Z_(c)(3900)

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Science china(Physics,Mechanics & Astronomy) 2024年第9期67卷 199-200页

作者： c.Hanhart Institute for Advanced Simulation Forschungszentrum JulichJilich D-52425Germany

The Standard Model of particle physics,which contains the field theories for the electro-weak interaction(QED)and the strong interaction(QcD),is an extremely successful theory describing a huge variety of phenomena at... 详细信息

关键词： interaction atomic describing

Influence of B4c and ZrB2 reinforcements on microstructural,mechanical and wear behaviour of AA 2014 aluminium matrix hybrid composites

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Defence Technology（防务技术） 2024年第10期40卷 242-254页

作者： Ramesh Babu R Rajendran c Saiyathibrahim A Rajkumar Velu Department of Mechanical Engineering Karpagam Institute of TechnologyCoimbatore 641105India Department of Mechanical Engineering Sri Krishna College of Engineering and TechnologyCoimbatore 641008India Department of Mechanical Engineering Indian Institute of Technology JammuJammu and Kashmir 181221India

considering their affordability and high strength-to-weight ratio,lightweight aluminium alloys are the subject of intensive research aimed at improving their properties for use in the aerospace *** research effort aims to develop novel hybrid composites based on AA 2014 alloy through the use of liquid metallurgy stir casting to reinforce dual ceramic particles of Zirconium Diboride(ZrB_(2))and Boron carbide(B4c).The weight percentage(wt%)of ZrB_(2) was varied(0,5,10,and 15),while a constant 5 wt%of B4c was maintained during this *** as-cast samples have been assessed using an Optical Microscope(OM)and a Scanning Electron Microscope(SEM)with Energy Dispersive Spectroscopy(EDS).The properties such as hardness,tensile strength,and wear characteristics of stir cast specimens were assessed to examine the impact of varying weight percentages of reinforcements in AA 2014 *** particular,dry sliding wear behaviour was evaluated considering varied loads using a pin-on-disc *** the weight%of ZrB_(2) grew and B4c was incorporated,hybrid composites showed higher hardness,tensile strength,and wear ***,the incorporation of a cumulative reinforcement consisting of 15 wt%ZrB_(2) and 5 wt%B4c resulted in a significant 31.86%increase in hardness and a 44.1%increase in tensile strength compared to AA 2014 *** addition,it has been detected that wear resistance of hybrid composite pin(containing 20 wt%cumulative reinforcement)is higher than that of other stir cast wear test pins during the whole range of applied *** surfaces of tensile specimens showed ductile fracture in the AA 2014 matrix and mixed mode for hybrid *** surfaces obtained employing higher applied load indicated abrasive wear with little plastic deformation for hybrid composites and dominant adhesive wear for matrix ***,the superior mechanical and tribological performance of hybrid composites can be attributed to dual reinforcement pa

关键词： AA 2014 alloy Stir casting Hybrid composite Hardness Tensile strength Specific wear rate

Light sheet microscope scanning of biointegrated microlasers for localized refractive index sensing

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Photonics Research 2024年第8期12卷 1673-1680页

作者： ROSS c.cOWIE MARcEL ScHUBERT SUPA School of Physics and AstronomyUniversity of St AndrewsSt AndrewsUK Humboldt centre for Nano and Biophotonics Department of ChemistryUniversity of CologneCologneGermany

Whispering gallery mode(WGM)microlasers are highly sensitive to localized refractive index changes allowing to link their emission spectrum to various chemical,mechanical,or physical *** recently found applications in biological studies within single cells,in three-dimensional samples such as multicellular spheroids,or in ***,detailed studies of biological samples also need to account for the structural heterogeneity of tissues and live animals,therefore requiring a combination of high-resolution microscopy and laser ***,we design and construct a light sheet fluorescence microscope with a coupled spectrometer for use in microlaser studies for combined high-resolution,high-speed imaging and WGM spectral *** light sheet illumination profile and the decoupled geometry of excitation and emission hereby directly affect the lasing and sensing properties,mainly through geometric constraints and by light coupling *** demonstrate the basic working principle of microlaser spectroscopy under light sheet excitation and measure the absolute refractive index within agarose and in zebrafish tail muscle *** further analyze the light coupling conditions that lead to the occurrence of two separate oscillation *** so-called cross modes can be scanned around the entire microlaser surface,which allows to estimate a surface-averaged refractive index profile of the microlaser environment.

关键词： refractive index excitation

A toast to a zebrafish germ cell induction cocktail

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Science china(Life Sciences) 2024年第6期67卷 1314-1315页

作者： Mary c.Mullins Department of cell and Developmental Biology University of Pennsylvania Perelman School of MedicinePhiladelphia 19104USA

The zebrafish field is ringing in the new year with a publication from Yonghua Sun's laboratory(Wang et al.,2023)of a cocktail of germline factors that can induce all cells of the zebrafish embryo into primordial germ cells(PGcs)at phenomenal *** major advance is not only of great interest to germ cell biologists,but it has important applications to the entire zebrafish field,as shown in Wang et al.(2023).

关键词： fish zebra field

convergence,Scalarization and continuity of Minimal Solutions in Set Optimization

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Journal of the Operations Research Society of china 2024年第3期12卷 773-793页

作者： Karuna c.S.Lalitha Department of Mathematics University of DelhiDelhiDelhi110007India Department of Mathematics University of Delhi South CampusNew DelhiDelhi110021India

The paper deals with the study of two different aspects of stability in the given space as well as the image space,where the solution concepts are based on a partial order relation on the family of bounded subsets of a real normed linear *** first aspect of stability deals with the topological set convergence of families of solution sets of perturbed problems in the image space and Painlevé–Kuratowski set convergence of solution sets of the perturbed problems in the given *** convergence in the given space is also established in terms of solution sets of scalarized perturbed *** second aspect of stability deals with semicontinuity of the solution set maps of parametric perturbed problems in both the spaces.

关键词： Topological convergence Painlevé-Kuratowski convergence Upper semicontinuity Lower semicontinuity Stability Scalarization

Performance of evolutionary optimized machine learning for modeling total organic carbon in core samples of shale gas fields

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Petroleum 2024年第1期10卷 150-164页

作者： Leonardo Goliatt c.M.Saporetti L.c.Oliveira E.Pereira Department of computational and Applied Mechanics Federal University of Juiz de ForaJuiz de ForaBrazil Department of computational Modeling Polytechnic InstituteRio de Janeiro State UniversityNova FriburgoBrazil Petrobras Rio de JaneiroBrazil Department of Stratigraphy and Paleontology Rio de Janeiro State UniversityRio de JaneiroBrazil

Rock samples'TOc content is the best indicator of the organic matter in source *** origin rock samples’analysis is used to calculate it manually by *** method requires time and resources because it relies on samples from many well intervals in source ***,research has been done to aid this *** learning algorithms can estimate total organic carbon instead of well logs and stratigraphic *** light of these efforts,the current work present a study on automating the total organic carbon estimation using machine learning approaches improved by an evolutionary methodology to give the model flexibility and *** algorithms,differential evolution,particle swarm optimization,grey wolf optimization,artificial bee colony,and evolution strategies were used to improve machine learning models to predict *** six metaheuristics were integrated into four machine learning methods:extreme learning machine,elastic net linear model,linear support vector regression,and multivariate adaptive regression *** samples from the YuDong-Nan shale gas field,located in the Sichuan basin,were used to evaluate the hybrid *** findings show that combining machine learning models with an evolutionary algorithms in a hybrid fashion produce flexible models that accurately predict *** results show that,independent of the metaheuristic used to guide the model selection,optimized extreme learning machines attained the best performance scores according to six *** hybrid models can be used in exploratory geological research,particularly for unconventional oil and gas resources.

关键词： Total organic carbon Hybrid models Automated machine learning Evolutionary algorithms Geology

A perspective on utilizing the minority stress model for HIV and mental health care for men who have sex with men

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Asian Pacific Journal of Tropical Medicine 2024年第8期17卷 333-334页

作者： Rowalt c.Alibudbud Department of Sociology and Behavioral Sciences De La Salle UniversityManilaPhilippines

In 2022,the Joint United Nations Programme on HIV/AIDS(UNAIDS)and the World Health Organization(WHO)called upon global,regional,national,and local stakeholders to embrace a holistic approach to person-centered HIV prevention,treatment,and care[1].This approach emphasizes integrating mental health and psychosocial support services into existing frameworks[1].It recognizes the critical role these services play in addressing mental distress and improving the overall well-being and quality of life for people living with HIV[1].In light of men who have sex with men(MSM)remaining a key population affected by HIV[1],it becomes imperative to delve into the shared factors that influence their HIV care and mental health,among which minority stress stands out as a critical consideration.

关键词： prevention distress stress