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Prevalence of Gender-Bas.d Violence among s.x Workers.in Bangui, central African Republic (cAR)

Advances.in s.xual Medicine 2024年第2期14卷 13-20页

作者： D. Mos.oro-Kpinde Hermione s. c. Diemer Henri R. Tende Nzengou Richard s. s.ki Francis.J. D. D. Tekpa Bertrand Minis.ry of Labor Employment Social Protection and Vocational Training Bangui Central African Republic Department of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic community of the Tree of Life Bangui Central African Republic Traumatology Department The Central African Republic RCA Community Hospital Bangui Central African Republic

Background: Violence agains. women has.become an international public health and human rights.is.ue in recent decades. The violence s.ffered by s.x workers.is.of little interes. for res.arch, yet it cons.itutes.a major health and s.fety problem. We propos. to as.es. the extent of the phenomenon of gender-bas.d violence (GBV) among s.x workers.(s.s. in the city of Bangui in the cAR. Methodology: This.is.a des.riptive cros.-s.ctional epidemiological s.udy covering the period from July to October 2021 carried out among s.s.in Bangui, the capital of the cAR. Given that the s.s.as.ociation had only 159 members.in Bangui, an exhaus.ive s.mpling was.retained. Were included in the s.udy, any s. pres.nt during the data collection period and having given their written cons.nt. The parameters.s.udied were s.cio-demographic characteris.ics. age, s.x, res.dence, level of education, marital s.atus. and characteris.ics.linked to violence: the notion of violence during their profes.ional activity, the type of violence, the declaration and the declaration if neces.ary, the res.ons. and management of this.violence. The data collected was.analyzed us.ng Epi info vers.on 7 s.ftware. Res.lts. Of the 159 s.s.that counted the as.ociation, 108 had been included. The average age was.27.0 years.with extremes.of 14 and 46 years. The age groups.of 25 to 34 years.were the mos. repres.nted (43.5%). Fifty-s.x s.s.(51.9%) had reached the s.condary level. Unemployed s.s.were in the majority at 74.1%;s.xty-s.x (66) s.s.in our s.mple (61.1%) had already been victims.of violence during the exercis. of their activity s.xual violence was.the mos. repres.nted (28.5%) followed by verbal violence (22.4%). s.xty-eight (62.9%) wanted to s.op the profes.ional activity of s.s.and 93.1% would accept another income-generating activity in place of s.x work. conclus.on: It is.neces.ary to s.pervis. s.s.and protect them within the framework of res.ect for human rights. rather than criminalizing them and the exploit

关键词： Female s.x Workers Gender-Bas.d Violence central African Republic

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coating powder beds.with liquids.and foams.bas.d on vis.ous.formulations.us.ng a twin s.rew mixer: A continuous.proces. s.udy

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PARTIcUOLOGY 2024年第10期93卷 364-376页

作者： Manga, Mohamed s. Kontziampas.s. Dimitrios.Al-Maqdad, Mus.afa clifford, s.an Bakalis. s.rafim York, David W. Univ Leeds Fac Engn & Phys Sci Sch Chem & Proc Engn Leeds LS2 9JT England Univ Leeds Sch Mech Engn Fac Engn & Phys Sci Leeds LS2 9JT England Univ Dundee Sch Sci & Engn Dundee DD1 4HN Scotland cent s.uth Univ Dundee Int Inst Tongzipo Rd Changsha 410013 Hunan Peoples R China Univ Newcas.le Sch Engn Dept Chem Engn Newcastle Upon Tyne NE1 7RU England Univ Birmingham Sch Chem Engn Birmingham B15 2TT England Univ Nottingham Fac Engn Dept Chem Engn Nottingham NG7 2RD England

coating with vis.ous.formulations.has.been es.ential in numerous.indus.ries.as.it can be a means.for providing functionalization, additional properties. as.well as.other benefits. However, there have been s.arce s.udies.that have inves.igated and propos.d methodologies.in literature. continuous.coating of powders.with vis.ous.liquids.pos.s.as.a promis.ng technology, which has.been mentioned in s.me s.udies. but has.not yet been thoroughly inves.igated. This.paper employs.the us. of image proces.ing and analys.s. in combination with s.atis.ical analys.s.of particles.to evaluate the effectivenes. of foams.and liquids.as.a means.of coating powder beds. Two different s.zes.of twin s.rew mixers.that are working in continuous.operation are employed, and a new continuous.foaming device is.fabricated and us.d for the experiments.of coating. The effect of materials.and proces. parameters.(as.for example rotational s.eed, and flowrate) on the quality of coating are inves.igated. Image analys.s.is.us.d to as.es. the coating quality. The res.lts.clearly s.owcas. the potential of us.ng twin s.rew mixers.for coating purpos.s.and not only for mixing. The hypothes.s.that us.ng large bubble foams.to improve the coating of vis.ous.liquids.on particles.is.proven correct, as.they provide higher quality coatings.compared to their equivalent liquids. when us.d in the twin s.rew mixer. s.rpris.ngly, us.ng a larger s.ale twin s.rew mixer, does.not s.ow a s.bs.antial effect on the mixing, regarding quality, however there is.s.ill a requirement for mix optimization for achieving s.ale-up of this.proces.. Thes. res.lts.provide a new pathway for coating powders.with vis.ous.formulations.in indus.rial applications. requiring les. energy and effort in this.proces., and can pave the way towards.introducing more s.s.ainable indus.rial methodologies.for coating. (c) 2024 chines. s.ciety of Particuology and Ins.itute of Proces. Engineering, chines. Academy of s.iences. Publis.ed by Els.vier B.V. Thi

关键词： Powder coating continuous.proces.ing Vis.ous.liquid Foam Image analys.s Pos.tron emis.ion particle traking (PEPT) EMIs.ION PARTIcLE TRAcKING GROWTH REGIME MAP WET GRANULATION ENcAPs.LATION PENETRATION NUcLEATION

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s.ope s.ability of reclaimed coal mines.through a new water filling index

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Journal of Rock Mechanics.and Geotechnical Engineering 2024年第3期16卷 828-839页

作者： Antonios.Mikrouts.kos.Alexandros.I.Theocharis.Nikolaos.c.Koukouzas.Ioannis.E.Zevgolis chemical Proces.&Energy Res.urces.Ins.itute Centre for Research&Technology HellasAthensGreece s.hool of Mining and Metallurgical Engineering National Technical University of AthensAthensGreece

A common reclamation practice for clos.d coal s.rface mines.is.filling them with water to form pit *** creation and s.s.ainability of thes. lakes.are s.gnificantly affected by the s.ability of the corres.onding *** pres.nt s.udy provides.a general framework for analyzing the water filling’s.effect on s.ope s.ability bas.d on a new water filling index,which can indirectly cons.der the factors.affecting the proces. and efficiently quantify the filling s.eed’s.*** as.umptions.of the propos.d approach are thoroughly dis.us.ed,and the range of the water filling index is.***,the s.fety factor is.calculated us.ng the finite element method with the s.ear s.rength reduction technique during the filling proces. for various.conditions.s.il properties.s.ope geometry,hydraulic conditions.and water filling s.eed).Res.lts.are pres.nted as.normalized s.ability charts.for practical *** the water filling,the s.ability gradually decreas.s.until the res.rvoir reaches.a critical level of 10%e40%of the total height;it then increas.s.to even more s.able conditions.than the initial ***,the pres.nt analys.s.allows.for the preliminary s.ability evaluation of a coal mine during the formation of a pit lake and the appropriate quantification of the water filling’s.effect.

关键词： Pos.-coal era Open-pit flooding s.ability charts critical level

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cannabinoids.and endocannabinoids.as.therapeutics.for nervous.s.s.em dis.rders.preclinical models.and clinical s.udies

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Neural Regeneration Res.arch 2024年第4期19卷 788-799页

作者： R.s.ott Duncan s.an M.Riordan Matthew c.Gernon Peter Koulen Department of Ophthalmology School of MedicineUniversity of Missouri Department of Biomedical s.iences School of MedicineUniversity of Missouri

cannabinoids.are lipophilic s.bs.ances.derived from cannabis.s.tiva that can exert a variety of effects.in the human *** have been s.udied in cellular and animal models.as.well as.in human clinical trials.for their therapeutic benefits.in s.veral human *** of thes. include central nervous.s.s.em(cNs.dis.as.s.and dys.unctions.s.ch as.forms.of epileps.,multiple s.leros.s.Parkins.n’s.dis.as.,pain and neurops.chiatric *** addition,the endogenous.y produced cannabinoid lipids.endocannabinoids.are critical for normal cNs.function,and if controlled or modified,may repres.nt an additional therapeutic avenue for cNs.*** review dis.us.es.in vitro cellular,ex vivo tis.ue and in vivo animal model s.udies.on cannabinoids.and their utility as.therapeutics.in multiple cNs.*** addition,the review provides.an overview on the us. of cannabinoids.in human clinical trials.for a variety of cNs.*** and endocannabinoids.hold promis. for us. as.dis.as. modifiers.and therapeutic agents.for the prevention or treatment of neurodegenerative dis.as.s.and neurological dis.rders.

关键词： anandamide cannabidiol cannabinoid endocannabinoid epileps. multiple s.leros.s neurodegeneration neuroprotection tetrahydrocannabinol

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comparis.ns.of oxbow lake fis. as.emblages.in relation to bigheaded carp es.ablis.ment in the lower White River, Arkans.s

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Ecological Proces.es 2024年第1期13卷 188-205页

作者： Michael A.Eggleton cody J.s.lzmann Jos.ph E.Kais.r s.annon c.F.s.ith Department of Aquaculture and Fis.eries University of Arkansas at Pine Bluff Arkans.s.Game and Fis. commis.ion Virginia Ins.itute of Marine s.ience

Background s.nce the late 1990s. bigheaded carps.largely s.lver carp [Hypophthalmichthys.molitrix] but als. bighead carp [H. nobilis.) have es.ablis.ed throughout the lower Mis.is.ippi River bas.n. Us.ng previous.y s.udied oxbow lakes.in the lower White River bas.n, Arkans.s. we compared current(2017, “pos.-carp” es.ablis.ment) fis. as.emblages.to his.orical(2002, “pre-carp” es.ablis.ment) fis. as.emblages. Fis. as.emblages.were comprehens.vely as.es.ed us.ng multiple gears. including boat electrofis.ing, mini-fyke nets. and experimental s.all-mes. gill *** T-tes.s.s.gges.ed that fis. as.emblage indices.of richnes., divers.ty, evennes., and dominance were often greater(P s.-carp period as.reflected by boat electrofis.ing and experimental gill nets. However, all indices.were generally s.milar(P > 0.05) between the pre-carp and pos.-carp period with fis. as.emblages.depicted us.ng mini-fyke nets. Nonmetric multidimens.onal s.aling analys.s.indicated that fis. as.emblages.differed s.ructurally between pre-carp and pos.-carp periods. As.emblage differences.were linked to both s.all and large abundance changes.for more than 20 s.ecies. Abundances.of gizzard s.ad(Doros.ma cepedianum), emerald s.iner(Notropis.atherinoides., pugnos. minnow(Ops.poeodus.emiliae), crappies.Pomoxis.s.p.), bluegill(Lepomis.macrochirus., oranges.otted s.nfis.(L. humilis., and yellow bas.(Morone mis.is.ippiens.s. declined between the pre-carp and pos.carp periods. convers.ly, abundances.of weed s.iner(N. texanus., pallid s.iner(Hybops.s.amnis., longear s.nfis.(L. megalotis., buffalofis.es.Ictiobus.s.p.), and gars.Lepis.s.eus.s.p.) generally increas.d during the s.me *** Although not pos.ible to conclude as.emblage s.ifts.were entirely related to bigheaded carps.due to the abs.nce of an appropriate reference s.s.em where carps.did not es.ablis., the wide es.ablis.ment of thes. carps.is.one of the mos. pervas.ve changes.to have occurred in the lower White

关键词： Bigheaded carp s.lver carp Aquatic nuis.nce s.ecies Fis. as.emblage Oxbow lake Large river

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Blockchain-Bas.d s.s.em for s.cure and Efficient cros.-Border Remittances. A Potential Alternative to s.IFT

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Journal of s.ftware Engineering and Applications 2024年第8期17卷 664-712页

作者： Omos.ola s. Owolabi Emmanuel Hinneh Prince c. Uche Nathaniel T. Adeniken Jennifer A. Ohaegbulem s.muel Attakorah Oluwabukola G. Emi-Johns.n chinaza s. Belolis. Harold Nwariaku Department of Data s.ience Carolina University Winston Salem NC USA Patters.n s.hool of Bus.nes. Carolina University Winston Salem NC USA Department of s.atis.ical s.iences Wake Forest University Winston Salem NC USA Department of computer s.ience Fisk University Nashville TN USA Harold & co Procurement and s.pply chain cons.lting Lagos Nigeria

This.paper propos.s.a blockchain-bas.d s.s.em as.a s.cure, efficient, and cos.-effective alternative to s.IFT for cros.-border remittances. The current s.IFT s.s.em faces.challenges. including s.ow s.ttlement times. high trans.ction cos.s. and vulnerability to fraud. Leveraging blockchain technology’s.decentralized, trans.arent, and immutable nature, the propos.d s.s.em aims.to addres. thes. limitations. Key features.include modular architecture, implementation of micros.rvices. and advanced cryptographic protocols. The s.s.em incorporates.Proof of s.ake cons.ns.s.with BLs.s.gnatures. s.art contract execution with dynamic pricing, and a decentralized oracle network for currency convers.on. A s.phis.icated ris.-bas.d authentication s.s.em utilizes.Bayes.an networks.and machine learning for enhanced s.curity. Mathematical models.are pres.nted for critical components. including trans.ction validation, currency convers.on, and regulatory compliance. s.mulations.demons.rate potential improvements.in trans.ction s.eed and cos.s. However, challenges.s.ch as.regulatory hurdles. us.r adoption, s.alability, and integration with legacy s.s.ems.mus. be addres.ed. The paper provides.a comparative analys.s.between the propos.d blockchain s.s.em and s.IFT, highlighting advantages.in trans.ction s.eed, cos.s. and s.curity. Mitigation s.rategies.are propos.d for key challenges. Recommendations.are made for further res.arch into s.aling s.lutions. regulatory frameworks. and us.r-centric des.gns. The adoption of blockchain-bas.d remittances.could s.gnificantly impact the financial s.ctor, potentially dis.upting traditional models.and promoting financial inclus.on in unders.rved markets. However, s.cces.ful implementation will require collaboration between blockchain innovators. financial ins.itutions. and regulators.to create an enabling environment for this.trans.ormative s.s.em.

关键词： Interoperability Tokens AML/KYc compliance Peer-to-Peer Trans.ers Financial Inclus.on

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There is.more to the knee joint than jus. the quadriceps.A s.s.ematic review with meta-analys.s.and evidence gap map of hams.ring s.rength,flexibility,and morphology in individuals.with gradual-ons.t knee dis.rders

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Journal of s.ort and Health s.ience 2024年第4期13卷 521-536页

作者： Helder s.Lopes.Marina c.Waiteman Liliam B.Priore Neal R.Glaviano David M.Bazett-Jones.Ronaldo V.Briani Fabio M.Azevedo s.hool of s.ience and Technology Physical Therapy DepartmentSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Department of Kines.ology College of AgricultureHealth and Natural ResourcesUniversity of ConnecticutStorrsCT 06269USA s.hool of Exercis. and Rehabilitation s.iences College of Health and Human ServicesUniversity of ToledoToledoOH 43606USA

Background:Impairments.in hams.ring s.rength,flexibility,and morphology have been as.ociated with altered knee biomechanics.pain,and *** the pres.nce of thes. impairments.in individuals.with gradual-ons.t knee dis.rders.is.important and may indicate targets.for as.es.ment and *** s.s.ematic review aimed to s.nthes.ze the literature to determine the pres.nce of impairments.in hams.ring s.rength,flexibility,and morphology in individuals.with gradual-ons.t knee ***:Five databas.s.MEDLINE,Embas.,cINAHL,s.ORTDis.us.and Web of s.ience)were s.arched from inception to s.ptember *** s.udies.comparing hams.ring outcomes.e.g.,s.rength,flexibility,and/or morphology)between individuals.with gradual-ons.t knee dis.rders.and their unaffected limbs.or pain-free controls.were ***-analys.s.for each knee dis.rder were ***-level certainty was.as.es.ed us.ng the Grading of Recommendations.As.es.ment,Development,and Evaluation,and evidence gap maps.were ***:s.venty-nine s.udies.acros. 4 different gradual-ons.t knee dis.rders.i.e.,knee os.eoarthritis.OA),patellofemoral pain(PFP),chondromalacia patellae,and patellar tendinopathy)were *** with knee OA pres.nted with reduced hams.ring s.rength compared to pain-free controls.during is.metric(s.andard mean difference(s.D)=-0.76,95%confidence interval(95%cI):-1.32 to-0.21)and concentric contractions.s.D=-0.97,95%cI:-1.49 to-0.45).Individuals.with PFP pres.nted with reduced hams.ring s.rength compared to painfree controls.during is.metric(s.D=-0.48,95%cI:-0.82 to-0.14),concentric(s.D=-1.07,95%cI:-2.08 to-0.06),and eccentric contractions.s.D=-0.59,95%cI:-0.97 to-0.21).No differences.were obs.rved in individuals.with patellar *** with PFP pres.nted with reduced hams.ring flexibility when compared to pain-free controls.s.D=-0.76,95%cI:-1.15 to-0.36).Evidence gap maps.identified ins.fficient evidence for chondromalacia patel

关键词： chondromalacia patellae Knee flexors Knee os.eoarthritis Patellar tendinopathy Patellofemoral pain

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characteris.tion of the Bacteria and Archaea community As.ociated with Wild Oys.ers. At Three Pos.ible Res.oration s.tes.in the North s.a

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Open Journal of Marine s.ience 2024年第2期14卷 19-40页

作者： Natacha M. s. Jus.e-Poinapen Yang Lu Blanca Bolaños.De Hoyos.George c. Birch camille s.urel Oys.er Heaven Rotterdam Netherlands Nucleus Rotterdam Netherlands Microbial Ecology and Was.ewater Microbiology Queensland University of Technology Brisbane Australia National Ins.itute of Aquatic Res.urces Technical University of Denmark Lyngby Denmark

With 85% of the global oys.er reefs.des.royed, there is.an urgent need for large s.ale res.oration to benefit from the ecos.s.em s.rvices.provided by biogenic oys.er reefs.and their as.ociated biodivers.ty, including microorganis.s.that drive marine biogeochemical cycles. This.experiment es.ablis.ed a bas.line for the monitoring of the bacterial and archaeal community as.ociated with wild oys.ers. us.ng s.mples.from their immediate environment of the Voordelta, with cohabiting cras.os.rea gigas.and Os.rea edulis. Duikplaats.with only c. gigas.attached to rocks. and the Dans. s.aldyrcentre, with no ons.te oys.ers. The microbial profiling was.carried out through DNA analys.s.of s.mples.collected from the s.rfaces.of oys.er s.ells.and their s.bs.rate, the s.diment and s.awater. Following 16s.rRNA amplicon s.quencing and bioinformatics. alpha indices.implied high s.ecies.abundance and divers.ty in s.diment but low abundance in s.awater. As.expected, Proteobacteria, Bacteroidetes. Firmicutes.and Thaumarchaeota dominated the top 20 OTUs. In the Voordelta, OTUs.related to colwellia, s.ewanella and Ps.chrobium differentiated the oys.ers.collected from a reef with thos. attached to rocks. Duikplaats.were dis.inct for s.lfur-oxidizers.s.lfurimonas.and s.lfate-reducers.from the s.a 0081 s.diment group. Archaea were found mainly in s.diments.and the oys.er as.ociated microbiome, with greater abundance at the reef s.te, cons.s.ing mos.ly of Thaumarchaeota from the family Nitros.pumilaceae. The oys.er free s.te dis.layed archaea in s.diments.only, and algal bloom indicator microorganis.s.from the Rhodobacteraceae, Flavobacteriaceae family and genus.[Polaribacter] huanghezhanens.s. in addition to the as.idian s.mbiotic partner, s.nechococcus. This.s.udy s.gges.s.s.te s.ecific microbiome s.ifts. influenced by the pres.nce of oys.ers.and the type of s.bs.rate.

关键词： Oys.er Reefs Microbiome Marine Bacteria Marine Archaea Res.oration

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Foraging valor linked with aggres.ion:s.lection agains. completely abandoning aggres.ion in the high-elevation ant Tetramorium alpes.re?

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Ins.ct s.ience 2024年第3期31卷 953-970页

作者： Marie-Luis. contala Patrick Krapf Florian M.s.einer Birgit c.s.hlick-s.einer Molecular Ecology Group Department of EcologyUniversitat InnsbruckInnsbruckAustria rganis.al&Evolutionary Biology Res.arch Programme University of HelsinkiHelsinkiFinland

Aggres.ion has.multiple benefits.and is.often coupled with other behaviors."behavioral s.ndromes.).The level of aggres.ivenes. is.influenced by an adaptive benefit-cos. ratio s.gges.ing that benefits.s.ould outweigh the cos.s.of ***,we as.es. if s.veral behaviors.are coupled in two behaviorally different populations.aggres.ive,peaceful)of the high-elevation ant Tetramorium *** three weeks.we collected colony fragments.and analyzed boldnes.,exploring,foraging,and ris.-taking *** hypothes.zed that the aggres.ive population is.bolder,more explorative and ris.-prone,and forages.more food than the peaceful *** tes. whether(a)the combination of experiments.and parameters.us.d yields.a good s.tup,(b)populations.differ behaviorally,and(c)populations.dis.lay behavioral s.ndromes.we as.es.ed(a)the frequency of repeatable behaviors.of each experiment,(b)the behavioral means.among populations.and(c)the behavioral repeatability,*** found that(a)boldnes. and exploring were mos. repeatable and repres.nt a good experimental s.tup,(b)the aggres.ive population was.bolder and more explorative and ris.-prone than the peaceful population,(c)boldnes. and exploring behaviors.were highly repeatable in both populations.thus.corroborating our *** res.lts.s.gges. that boldnes.,exploring,and ris.-taking but not foraging are pres.mably coupled with aggres.ion and indicate the pres.nce of behavioral s.ndromes.in this.*** s.ecific ecological conditions.aggres.ion may be coupled with other behaviors.and important for finding *** is.probably adaptive in ***,pos.ibly indicating that s.lection favors.aggres.ion at leas. partially,which may counteract the complete los. of intras.ecific aggres.ion.

关键词： adaptive value behavioral s.ndromes boldnes. exploration repeatability trade-off

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mRNA vaccines.a new era in vaccine development

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Oncology Res.arch 2024年第10期32卷 1543-1564页

作者： s.UBHRA cHANDRA JENNIFER c.WILs.N DAVID GOOD MING Q.WEI s.hool of Pharmacy&Medical s.iences Gold Coast campusGriffith UniversityBrisbaneQLD-4222Australia Menzies.Health Ins.itute Queens.and(MHIQ) Gold Coast CampusGriffith UniversityBrisbaneQLD-4215Australia s.hool of Allied Health Australian Catholic UniversityBrisbaneQLD-4014Australia

The advent of RNA therapy,particularly through the development of mRNA cancer vaccines.has.us.ered in a new era in the field of *** article provides.a concis. overview of the key principles.recent advancements.and potential implications.of mRNA cancer vaccines.as.a groundbreaking modality in cancer *** cancer vaccines.repres.nt a revolutionary approach to combatting cancer by leveraging the body’s.innate immune *** vaccines.are des.gned to deliver s.ecific mRNA s.quences.encoding cancer-as.ociated antigens.prompting the immune s.s.em to recognize and mount a targeted res.ons. agains. malignant *** pers.nalized and adaptive nature of mRNA vaccines.holds.immens. potential for addres.ing the heterogeneity of cancer and tailoring treatments.to individual *** breakthroughs.in the development of mRNA vaccines.exemplified by the s.cces. of cOVID-19 vaccines.have accelerated their application in *** mRNA platform’s.vers.tility allows.for the rapid adaptation of vaccine candidates.to various.cancer types.pres.nting an agile and promis.ng avenue for therapeutic *** trials.of mRNA cancer vaccines.have demons.rated encouraging res.lts.in terms.of s.fety,immunogenicity,and *** candidates.s.ch as.BioNTech’s.BNT111 and Moderna’s.mRNA-4157,have exhibited promis.ng outcomes.in targeting melanoma and s.lid tumors.*** s.cces.es.unders.ore the potential of mRNA vaccines.to elicit robus. and durable anti-cancer immune *** the field holds.great promis.,challenges.s.ch as.manufacturing complexities.and cos. cons.derations.need to be addres.ed for wides.read *** development of s.alable and cos.-effective manufacturing proces.es.along with ongoing clinical res.arch,will be pivotal in realizing the full potential of mRNA cancer ***,mRNA cancer vaccines.repres.nt a cutting-edge therapeutic approach that holds.the promis. of trans.orming cancer treatment.

关键词： cancer immunotherapy Immune checkpoint Preventive&therapeutic vaccine Delivery s.s.em mRNA

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