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Genomic surveillance of Nevada patients revealed prevalence of unique SARS-coV-2 variants bearing mutations in the RdRp gene

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Journal of Genetics and Genomics 2021年第1期48卷 40-51页

作者： Paul D.Hartley Richard L.Tillett David P.Aucoin Joel R.Sevinsky Yanji Xu Andrew Gorzalski Mark Pandori Erin Buttery Holly Hansen Michael A.Picker cyprian c.Rossetto Subhash c.Verma Nevada Genomics center RenoNV 89557USA University of Nevada RenoRenoNV 89557USA Nevada Institute of Personalized Medicine University of NevadaLas VegasNV 89154USA Department of Microbiology&Immunology University of NevadaReno School of MedicineRenoNV 89557USA Theiagen consulting LLCHighlands RanchCO 80128USA Nevada center for Bioinformatics RenoNV 89557USA Nevada State Public Health Laboratory RenoNV 89503USA Southern Nevada Public Health Laboratory of the Southern Nevada Health District Las VegasNV 89107USA

Patients with signs of cOVID-19 were tested through diagnostic RT-PcR for SARS-coV-2 using RNA extracted from the nasopharyngeal/nasal *** determine the variants of SARS-coV-2 circulating in the state of Nevada,specimens from 200 cOVID-19 patients were sequenced through our robust sequencing platform,which enabled sequencing of SARS-coV-2 from specimens with even very low viral loads,without the need of culture-based *** genome coverage allowed the identification of single and multi-nucleotide variants in SARS-coV-2 in the community and their phylogenetic relationships with other variants present during the same period of the *** report the occurrence of a novel mutation at 323aa (314aa of orf1b) of nsp12 (RNA-dependent RNA polymerase) changed to phenylalanine(F) from proline (P),in the first reported isolate of SARS-coV-2,*** 323F variant was present at a very high frequency in Northern *** modeling determined this mutation in the interface domain,which is important for the association of accessory proteins required for the *** conclusion,we report the introduction of specific SARS-coV-2 variants at very high frequency in distinct geographic locations,which is important for understanding the evolution and circulation of SARS-coV-2variants of public health importance,while it circulates in humans.

关键词： SARS-coV-2 cOVID-19 Genome enrichment nsp12 RdRp orf1b 314

Ti-47Al-2Mn-2Nb合金低温静态和动态拉伸性能及硼的影响

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金属学报 1999年第11期35卷 1139-1143页

作者：王瑜林栋梁周元鑫夏源明 c.c.Law 上海交通大学材料科学系教育部高温材料及高温测试开放实验室上海200030 中国科学技术大学近代力学系合肥230026 MaterialsandMechanicsEngineering UnitedTechnologiesCompany-Pratt&Whittney400MainStreetEastHartford

用常规拉伸和Ｈｏｐｋｉｎｓｏｎ拉杆技术，研究具有近全片层组织形变Ｔｉ－４７ＡＩ－ＺＭｎ－２Ｎｂ合金１８０Ｋ下静态（１０－５──１０－１ｓ－１）和动态（２０－１０３ｓ－１）拉伸性能及其受硼的影响，发现Ｔｉ－４７ＡＩ－２... 详细信息

用常规拉伸和Ｈｏｐｋｉｎｓｏｎ拉杆技术，研究具有近全片层组织形变Ｔｉ－４７ＡＩ－ＺＭｎ－２Ｎｂ合金１８０Ｋ下静态（１０－５──１０－１ｓ－１）和动态（２０－１０３ｓ－１）拉伸性能及其受硼的影响，发现Ｔｉ－４７ＡＩ－２Ｍｎ－２Ｎｂ和Ｔｉ－４７ＡＩ－２Ｍｎ－２Ｎｂ－１Ｂ合金１８０Ｋ下的拉伸强度均比室温高，静态（１０－５──１０－１ｓ－１）时与应变速率之间呈单对数线性关系，动态（１０—１０３ｓ－１）时呈线性关系．１．０Ｂ原子分数，％）仍能明显提高合金的静态和动态拉伸强度，但对拉伸塑性和断裂方式影响不大。

关键词： TiAl合金硼低温拉伸性能钛合金

Urban Development of Macao:challenges and Opportunities

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china city Planning Review 2016年第1期25卷 68-75页

作者： Roger c.K.chan Li caige Department of Urban Planning and Design University of Hong Kong Faulty of Architecture University of Hong Kong

This paper reviews the socio-economic development and the spatial evolution patterns of Macao. It argues that urbanization and intense land development have posed three challenges to Macao's future development pathway, namely, limited provision of resource, lack of diversification ofindustries, and incomplete planning legislation. The General Agreement on the cooperation between Guangdong and Macao signed in 2003 represents a strong policy incentive that offered a comprehensive institutional framework to promote economic integration. The Agreement is conducive to achieving economic development through proposing dynamic and diversified economic activities, which will also benefit tourism. The development of Hengqin will serve as a test bed for furthering the implementation of "one country, two systems" constitutional principle, which will also improve the existing regional cooperation mechanisms. A comprehensive urban planning system should be established to avoid marginalization in regional development. Better reallocation of resources and prevention of over-competition in the market are two critical components in achieving sustainable development of Macao.

关键词： planning regional integration Macao

Rectifying barrier at GaN/Sic hetero-junction studied with positron annihilation spectroscopy

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chinese Physics B 2005年第11期14卷 2293-2299页

作者：胡一帆 Beling c D Department of Physics Huazhong University of Science and Technology Wuhan 430074 China Department of Physics University of Hong Kong Hong Kong China

Positron annihilation spectroscopy on GaN films grown on Sic substrate with MBE are presented. It is shown that the GaN/Sic interface is rectifying towards positrons, such that positrons can only travel from Sic to GaN and not vice versa. Potential steps seen by the positron at the GaN/Sic interface are calculated from experimental values of electron and positron work function. This “rectifying” effect has been successfully mimicked by inserting a thin region of very high electric field in the Variable Energy Positron Fit （VEPF） analysis. The built-in electric field is attributed to different positron affinities, dislocation and/or interface defects at the GaN/Sic interface.

关键词： GaN Sic hetero-junction positron rectifying barrier

Delmar's Fundamentals of anatomy & physiology / Donald c. Rizzo.

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A study on fluorescence properties of Eu^(3+) ions in alkali lead tellurofluoroborate glasses

2001年

作者： Donald c. Rizzo.

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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Journal of Rare Earths 2010年第2期28卷 189-193页

作者： S.A.Saleem B.c.Jamalaiah A.Mohan Babu K.Pavani L.Rama Moorthy Department of Physics Sri Venkateswara University Department of Physics Sree Vidyanikethan Engineering College

Glasses with chemical composition of (in mol.%): 26 RF-20 PbO-10 TeO2-43 H3BO3-1 EuO3 (RLTB) were prepared by conventional melt quenching method. The Judd-Ofelt intensity parameters Ω2 and Ω6 were obtained from the absorption intensities of 7F0→5D2 and 7F0→5L6 transitions, respectively. In order to overcome the problem of applicability of Judd-Ofelt analysis at room temperature due to the overlapping of the transitions originating from 7F0 and 7F1 levels of Eu3+ ion, the effect of the thermalization on the ...

关键词： europium glasses Judd-Ofelt analysis fluorescence emission cross-sections optical gain parameters rare earths

Annual yields of multispecies grassland mesocosms outperformed monocultures across a drought gradient due to complementarity effects and rapid recovery

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Grassland Research 2023年第4期2卷 309-321页

作者： Eamon Haughey Jennifer c.McElwain John A.Finn Department of Natural Resources and the Environment Atlantic Technological UniversityGalwayIreland Botany Department School of Natural SciencesTrinity College DublinDublinIreland Teagasc Environment Research CentreJohnstown CastleWexfordIreland

Background:More frequent and severe drought events due to climate change pose a major challenge for sustainable forage production in managed *** study investigated whether multispecies grassland communities can provide greater resistance to and/or recovery from drought compared to monoculture ***:Mesocosms of Lolium perenne L.,cichorium intybus L.,Trifolium repens *** Trifolium pratense *** established as monocultures,and a four-species mixture.A drought gradient with five levels of water supply ranging from a mild to a severe treatment was applied for 10 weeks,in each of 2 *** biomass was harvested to assess drought resistance,drought recovery and annual *** mass density and specific root length were measured in Year ***:Across the drought gradient,four-species communities had significantly larger annual yields than each of the four monocultures,indicating transgressive *** was despite relatively low drought resistance for four-species communities compared with *** and *** *** of yields following drought was high for all ***:Multispecies swards with complementary traits can provide a viable adaptation option across a wide range of drought *** of a stress gradient methodology allowed a more detailed understanding of stress responses.

关键词： climate change drought forage production functional biodiversity perturbation gradient resilience root traits

Effective charge from lattice QcD

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chinese Physics c 2020年第8期44卷 23-32页

作者： Z.-F.cui J.-L.Zhang D.Binosi F.De Soto c.Mezrag J.Papavassiliou c.D.Roberts J.Rodríguez-Quintero J.Segovia S.Zafeiropoulos School of Physics Nanjing UniversityNanjing 210093China Institute for Nonperturbative Physics Nanjing UniversityNanjing 210093China Department of Physics Nanjing Normal UniversityNanjing 210023China European centre for Theoretical Studies in Nuclear Physics and Related Areas Villa TambosiStrada delle Tabarelle 286I-38123 Villazzano(TN)Italy Dpto.Sistemas Físicos Químicos y NaturalesUniv.Pablo de OlavideE-41013 SevillaSpain 6.IRFUCEAUniversitéParis-SaclayF-91191 Gif-sur-YvetteFrance Department of Theoretical Physics and IFIc University of Valencia and CSICE-46100ValenciaSpain Department of Integrated Sciences and center for Advanced Studies in Physics Mathematics and Computation University of Huelva E-21071 HuelvaSpain Aix Marseille Univ Universitéde ToulonCNRSCPTMarseilleFrance

Using lattice configurations for quantum chromodynamics(QcD)generated with three domain-wall fermions at a physical pion mass,we obtain a parameter-free prediction of QcD’s renormalisation-group-invariant process-independent effective charge,α^(k2).Owing to the dynamical breaking of scale invariance,evident in the emergence of a gluon mass-scale,m0=0.43(1)GeV,this coupling saturates at infrared momenta:α^(0)/π=0.97(4).Amongst other things:α^(k2)is almost identical to the process-dependent(PD)effective charge defined via the Bjorken sum rule;and also that PD charge which,employed in the one-loop evolution equations,delivers agreement between pion parton distribution functions computed at the hadronic scale and *** diversity of unifying roles played byα^(k^2)suggests that it is a strong candidate for that object which represents the interaction strength in QcD at any given momentum scale;and its properties support a conclusion that QcD is a mathematically well-defined quantum field theory in four dimensions.

关键词： running coupling quantum chromodynamics Dyson-Schwinger equations lattice field theory emer-gence of mass confinement

Parametric Modeling of Electromagnetically Induced Vibration Processes Occurring Within Induction Systems

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Journal of Iron and Steel Research International 2012年第S2期19卷 709-712页

作者： PETRYKOWSKI John c. SHI Yinghui Mechanical and Aerospace Engineering Department University of Dayton

A continuum based model is presented which identifies a favorable set of operational conditions whereby an effective and efficient electromagnetically induced vibratory motion can proceed within an induction ***, an analytical assessment is presented for the electromagnetic field and the electromagnetically induced acoustic field, with parametric factors incorporated into the model to permit a normal modes solution for the acoustic field which here is sensitive to the compliance of both the molten metal and the wall,as well as electromagnetic properties of the metal.A parametric analysis is presented which identifies the importance of matching the mechanical impedances of the melt-wall configuration so that the generation of acoustic energy within the melt system can be more effectively *** straight-forward calculations,presented for the acoustic field,may provide a more computationally efficient means for implementing process simulation studies for these systems.

关键词： induction systems low-frequency electromagnetic vibrating casting(LFEVc) normal modes