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真空 1980年第1期 76-106+62页

作者： c.f.weston 翁国屏

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORfBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORfBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORfBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Bayesian inference for dynamical systems

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Infectious Disease Modelling 2020年第1期5卷 221-232页

作者： weston c.Roda Department of Mathematical and Statistical Sciences University of AlbertaEdmontonAB T6G 2G1Canada

Bayesian inference is a common method for conducting parameter estimation for dynamical *** the prevalent use of Bayesian inference for performing parameter estimation for dynamical systems,there is a need for a formalized and detailed *** paper presents a comprehensive methodology for dynamical system parameter estimation using Bayesian inference and it covers utilizing different distributions,Markov chain Monte carlo(McMc)sampling,obtaining credible intervals for parameters,and prediction intervals for solutions.A logistic growth example is given to illustrate the methodology.

关键词： Bayesian Inference Model fitting Data Dynamical system Mathematical model

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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数字学习生态系统中的电子课本(英文)

华东师范大学学报（自然科学版） 2014年第2期 98-115页

作者： c.weston 英国学校学习科技、多塞特郡、T63TN 英国

本文认为,教育在本质上是交互性的而不只是信息的传播.如果遵循这个理论,尽管商业电子书作为独立的产品是可行的,但是电子课本还需要嵌入一个更广泛的数字生态系统来学习.这个生态系统,将包括许多不同形式的软件,提供交互性,报告交互性... 详细信息

本文认为,教育在本质上是交互性的而不只是信息的传播.如果遵循这个理论,尽管商业电子书作为独立的产品是可行的,但是电子课本还需要嵌入一个更广泛的数字生态系统来学习.这个生态系统,将包括许多不同形式的软件,提供交互性,报告交互性的成果,分析个别学生的能力和管理他们的进展.在这样的生态系统中,电子课本在支持开放标准的互操作性上发挥着至关重要的作用.本文将反映一些ISO/IEc研究中的主要结果.

关键词：数字学习生态系统电子课文 ISO IEc

Dynamic characteristics of a switch and crossing on the West coast main line in the UK

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Railway Engineering Science 2022年第2期30卷 183-203页

作者： Jou-Yi Shih Paul weston Mani Entezami clive Roberts Birmingham centre for Railway Research and Education University of BirminghamBirmingham B152TTUK ZynaMic Engineering AB 12070 StockholmSweden

Railway switches and crossings constitute a small fraction of linear track length but consume a large proportion of the railway track system maintenance *** switch and crossing(S&c)faults rarely prevent trains from running,switches and crossings are the source of many faults and need continual *** the rare occasions when trains are prevented from running the cost of the disruption is very *** monitoring of the point operating equipment that moves the switchblades has been in use for many years but condition monitoring of the state of the switch in terms of the support and mechanical damage as trains pass over has only recently started to become *** this end,it is important to understand the correlation between S&c faults and sensor data that can detect those *** paper assesses some of the data collected from multiple sensors variously positioned on and around a switch and crossing on the UK mainline for a few days of normal train ***,geophones,and strain gauges were installed at the locations where they were anticipated to be most *** at the load transfer point on the crossing nose were estimated from two separate strain gauge bridges and possible use of acceleration on the crossing is *** between different data are analysed and assessed and correlation between peak estimated load transfer forces and accelerations is *** on the analysis,conclusions are drawn about the different types of dynamic information around S&cs that can be obtained from a variety of sensor types.

关键词： Railway Accelerometer condition monitoring Impact force Switch and crossing Strain gauge

THERMODYNAMIc VARIATIONAL APPROAcH fOR cLIMB Of AN EDGE DISLOcATION

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Acta Mechanica Solida Sinica 2009年第5期22卷 426-435页

作者： A.c.f.cocks Department of Engineering Science University of OxfordParks RoadOxfordOX1 3PJUK

A general thermodynamic variational approach is applied to study the force on an edge dislocation, which drives the dislocation to climb. Our attention is focused on the physical mechanism responsible for dislocation climb. A dislocation in a material element climbs as a result of vacancies diffusing into or out from the dislocation core, with the dislocation acting as a source or a sink for vacancy diffusion in the material element. The basic governing equations for dislocation climb and the climb forces on the dislocation are obtained naturally as a result of the present thermodynamic variational approach.

关键词： dislocation climb driving forces variational principle

High Strain Rate Superplasticity in a Micro-grained Al-Mg-Sc Alloy with Predominant High Angle Grain Boundaries

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Journal of Materials Science & Technology 2012年第11期28卷 1025-1030页

作者： f. c. Liu Z.Y. Ma f. c. Zhang Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of SciencesShenyang 110016 China State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao 066004China

friction stir processing （fSP） was applied to extruded AI-Mg-Sc alloy to produce fine-grained microstructure with a grain size of 2.2μm. Electron backscatter diffraction （EBSD） result showed that the grain boundary misorientation distribution was very close to a random grain assembly for randomly oriented cubes. Super- plastic investigations in the temperature range of 425-500 ℃ and strain rate range of 1x100^-2-1x10 s^-1 showed that a maximum elongation of 1500% was achieved at 475 ℃ and a high strain rate of 1x100^-2-1x10 s^-1. The fSP AI-Mg-Sc exhibited enhanced superplastic deformation kinetics compared to that predicted by the constitutive relationship for superplasticity in fine-grained aluminum alloys. The origin for enhanced superplas- tic deformation kinetics in the fSP alloy can be attributed to its high fraction of high angle grain boundaries （HAGBs）. The analyses of the superplastic data and scanning electron microscopy （SEM） examinations on the surfaces of deformed specimens indicated that grain boundary sliding is the main superplastic deformation mechanism for the fSP AI-Mg-Sc alloy.

关键词： Superplasticity friction stir processing Aluminum Microstructure friction stir welding

Engineering vibration monitoring by GPS:long duration records

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Earthquake Engineering and Engineering Vibration 2009年第3期8卷 459-467页

作者： f.casciati c.fuggini Department of Structural Mechanics University of PaviaItaly

Monitoring the performance of any structure requires real-time measurements of the change of position of critical points. Different techniques can be used for this purpose, each one offering advantages and disadvantages. The technique based on satellite positioning systems （GPS, GLONASS and the future GALILEO） seems to be very promising at least for long period structures. The GPS in particular provides sampling rates that are able to track dynamic displacements with high accuracy. Its service ability is independent of atmospheric conditions, temperature variations and visibility of the monitored object. This paper investigates the reliability and accuracy of the measurements of dual frequency GPS receivers. A linear electromagnetic motor moves an object along a given direction. The changes of position are compared witb their estimates as recorded by a GPS receiver, whose antenna is located on the reference object. The comparison is based on sufficiently long records.

关键词： infrastructure monitoring global positioning system (GPS) delay positioning errors multi-path error signal geometric dilution of precision linear motor amplitudes power spectral densities