检索结果-南通市图书馆

Biomedical and Environmental Sciences 1992年第4期5卷 293-302页

作者： LOUISW.cHANG c.M.YANG c.f.chen J.f.DENG Departments of Pathology Pharmacology and Toxicology University ora rkansas for Medical Sciences Little RockThe Chang-Gung Medical College Kwai-sanNational Research Institute of Chinese MedicineThe Veteran's General Hospital-Taipei AR 72205TaipeiTaipeiTaipei Taiwan China

Young male rats were orally intubated with podophyllotoxin: Group I, control animals, orally fed with vehicle only; Group Ⅱ, fed with an initial dose of 5 ***-1 b.w., followed by a daily dose of 1.67 mg-kg-1 b.w. for 7d. Group III, fed with an initial dose of 15 ***-1 b.w., followed by a daily dose of 5 ***-1 b.w. for 7d. All animals were sacrificed 72 h after the last dosing.Histopathological examination revealed dose-related fatty change of the liver, atrophy andi degenerative changes of the intestinal epithelial linings and testicular seminiferous tubules. Depletion of the pancreatic acinar cell granules was also apparent in the Group III animals. No pathology, however, was observed in the kidneys. The present study demonstrated for the first time degenerative changes in the liver, intestine, testis, and pancreas of animals ingested podophyllotoxin. These pathological changes correlate well with the clinical signs/symptoms of abnormal liver function, abdominal pain and diarrhea, and reduced serum amylase in humans poisonded by podophyllum. Inhibition of protein synthesis and mitosis (disruption of microtubules) are believed to be the underlying mechanisms of these changes observed in the animals intoxicated by. podophyllotoxin.

关键词： Bajiaolian Effects on the Liver Experimental Podophyllotoxin Kidney Poisoning

维普期刊数据库

Experimental Podophyllotoxin (Bajiaolian) Poisoning:——Ⅰ. Effects on the Nervous System

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 1992年第4期5卷 283-292页

作者： LOUIS W.cHANG c.M.YANG c.f.chen J.f.DENG Departments of Pathology Pharmacology and Toxicology University of Arkansas for Medical Sciences Little RockThe Chang-Gung Medical College Kwai-sanNational Research Institute of Chinese MedicineThe Veteran General Hospital AR 72205TaipeiTaipeiTaipei Taiwan China

Bajiaolian, one of the species in the Mayapple family ( Podophyllum pelatum ), has been widely used as a traditional chinese herbal medicine for the remedies of snake bites, general weakness, poisons, condyloma accuminata, lymphadenopathy, and certain tumors in china. In Western medicine, Podophyllum was first used medically as a laxative in the early 19th century. Since 1940, the resin of podophyllum has also been used topically for various skin lesions, such as warts and condyloma. Human poisonings have been reported.An animal model was established to investigate the neurotoxic effects of Bajiaolian. Podophyllotoxin, the major active ingredient in Podophyllum, was injected (ip) to young adult male rats at doses of 0, 5, 10, or 15 mg-kg-1 b.w.. The animals were sacrificed 72 h after injection.Neuronal changes were readily observable in animals treated with 10 or 15 mg-kg-1 of the toxin. Edematous changes of the anterior horn motoneurons were observed in the spinal cord. No neuronal necrosis was found. The type of neuronal swelling is believed to be only a transient change and would probably subside with time if no further assaults occur. More serious and perhaps longer term of changes were found in the dorsal ganglion neurons and the nerve fibers (axons) in the central and peripheral nervous system. Severe depletion of the Nissl substance (RNA/polyribosomes) was observed in the dorsal root ganglion neurons. Alterations in these sensory neurons would give rise to and correlate with the sensory disturbances experienced by the patients. Bodian staining also revealed a dose-related increase in the coarseness (thickness) of the nerve fibers (axons) in the cerebellum, cerebral cortex, brainstem, and spinal cord.This is the first scientific study showing the neurotoxicity of Bajiaolian, a commonly used chinese herbal medicine. Toxicities on other organ systems by this drug certainly exist. caution should be exercised in the dispensing and usa

关键词： Bajiaolian Effects on the Nervous System Experimental Podophyllotoxin Poisoning

维普期刊数据库

Effects of Λ hyperons on the deformations of even–even nuclei

在线全文

学校读者我要写书评

暂无评论

chinese Physics c 2022年第6期46卷 212-218页

作者： c.f.chen Q.B.chen Xian-Rong Zhou Y.Y.cheng Ji-Wei cui H.-J.Schulze Department of Physics East China Normal UniversityShanghai 200241China School of Physics and Optoelectronic Engineering Xidian UniversityXi'an 710071China INfN Sezione di catania Dipartimento di FisicaUniversitádi CataniaVia Santa Sofia 6495123 CataniaItaly

The deformations of multi-Λ hypernuclei corresponding to even-even core nuclei ranging from^(8)Be to^(40)ca with 2,4,6,and 8 hyperons are studied using the deformed Skyrme-Hartree-fock *** is found that the deformations are reduced when adding 2 or 8 Λ hyperons,but enhanced when adding 4 or 6 Λ *** differences are attributed to the fact that Λ hyperons are filled gradually into the three deformed p orbits,of which the [110] 1/2^(-)orbit is prolately deformed and the degenerate [101]1/2^(-)and [101]3/2^(-)orbits are oblately deformed.

关键词： deformation even-even nuclei effects of hyperon(s)

维普期刊数据库

以微机为主体的单相异步电动机功率因数控制器

在线全文

学校读者我要写书评

暂无评论

电机与控制应用 1984年第5期 54-57页

作者： c.f.chen 杨宝龙

功率因数控制器(Pfc)是一种控制流到电动机电流、提高电动机效率而不影响机械功率输出的装置。这种装置具有按电动机负载断开或重新接通电动机电流的能力。此外,由于电动机带有 Pfc,I~2R 损耗降低,故电机运行温度较低。下面将先简单地讨... 详细信息

功率因数控制器(Pfc)是一种控制流到电动机电流、提高电动机效率而不影响机械功率输出的装置。这种装置具有按电动机负载断开或重新接通电动机电流的能力。此外,由于电动机带有 Pfc,I~2R 损耗降低,故电机运行温度较低。下面将先简单地讨论 Pfc 的原理,然后较详细地论述以微机为主体的Pfc。

关键词：单相异步电动机负载变化功率因数控制器微机

Effect of environmental factors on corrosion behavior of L360QcS pipeline steel in H2S/cO2 environments

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effect of environmental factors on corrosion behavior of L36...

尼柯尔斯(Nichols)图的直线逼近作图法

2015年第十四届全国应用化学年会

作者： X.S.huang Y.M.Qi c.f.chen H.B.Yu G.W.Lu

The present research investigated the effect of HS/cO partial pressure, sulphur deposition and corrosion inhibitor on the corrosion behaviour of L360 QcS pipeline steel in HS/cO environments by immersion tests, scanning electron microscope analysis and electrochemical measurements. The results show that the corrosion rate(cR) of L360 QcS steel decreased first and then increased with increasing P and *** cR is closely associated with the protectiveness of corrosion film. Sulphur deposition can cause an acceleration of the corrosion of steel in HS/cO environments. furthermore, the cR increased obviously with increasing P and PcO in sulphur deposition environments. After addition of continuous corrosion inhibitor, the cR decreased significantly in HS/cO environments. Prefilming corrosion inhibitor could enhance the inhibition effect in the presence of continuous corrosion inhibitor.

关键词： L360QcS pipeline steel Sulphur deposition H2S/cO2 corrosion continuous and prefilming corrosion inhibitor Immersion tests

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

机械工业自动化 1983年第1期 53-56页

作者： c.f.chen c.P.Kwong 黄雨祝

一.导言在频域分析中,广泛地使用了直线逼近的对数幅频特性曲线。Vogt和Younis建立了简单的类似幅频特性直线逼近的相频特性。在控制系统的设计中,尼柯尔斯图是经常用到的,但是尚无它的直线逼近作图,本文则介绍尼柯尔斯图的直线逼近作... 详细信息

一.导言在频域分析中,广泛地使用了直线逼近的对数幅频特性曲线。Vogt和Younis建立了简单的类似幅频特性直线逼近的相频特性。在控制系统的设计中,尼柯尔斯图是经常用到的,但是尚无它的直线逼近作图,本文则介绍尼柯尔斯图的直线逼近作图法。

关键词：尼柯尔斯图幅频特性相频特性直线逼近 Nichols 作图法柯尔

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国某些红黄壤中吸收性铵的解吸作用

土壤学报 1957年第4期 331-344页

作者：陈家坊中国科学院土壤研究所

1.土壤的吸收性铵可分为两部分,一部分易在蒸汽蒸馏情况迅速解吸。称之为“易解吸性铵”;另一部分则只能在强碱性条件下被蒸馏出来,称为“非解吸性铵”。2.对于红黄壤,“易解吸性铵”可能是R2O3引起的一种物理性吸附,其吸附量随介质的pH... 详细信息

1.土壤的吸收性铵可分为两部分,一部分易在蒸汽蒸馏情况迅速解吸。称之为“易解吸性铵”;另一部分则只能在强碱性条件下被蒸馏出来,称为“非解吸性铵”。2.对于红黄壤,“易解吸性铵”可能是R2O3引起的一种物理性吸附,其吸附量随介质的pH 值的增高而迅速增大。高岭土和斑脱土的“易解吸性铵”量很低,且与介质pH值无关。所有试样的“非解吸性铵”均与介质pH 无关。3.“易解吸性铵”中有29—45%可以在干燥器（放cacl2）中因脱水而损失。4.红壤的“易解吸性铵”量,与电解质浓度（低于0.1N 时）的关系,完全服从freun-dlich 方程式。其“非解吸性铵”则与浓度无关。5.铵质土的pH 与“易解吸性铵”含量具有一定关系,它可表示为:pH=αD+b;其中D 为“易解吸性铵”的每百克土壤中毫当量数;α为常数,在本试验中对于红壤标本其值为0.88,b 相当于“易解吸性铵”数值为零时铵质土的pH 值。6.用於洗涤的酒精浓度的变化,对于斑脱土的吸收性铵的总量不起影响,但对于土壤试样,则随酒精浓度的降低而减少其吸收性铵的总量,而其减少的部分,几乎全为“易解吸性铵”。

关键词：吸收性解吸作用 NH pH cI 红黄壤

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

误差常数的状态空间描述法

国外自动化 1980年第2期 46-47页

作者： c.f.chen R.E.Yates 王松才李俊朋

本文阐述应用状态空间描述和经典理论的对比方法求解有关系统的位置、速度和加速度误差常数。

关键词：状态空间空间描述极点经典点(数学) 加速度误差常数方程方程式描述法

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

几种水稻土对铵离子的吸附特性

土壤学报 1963年第2期 63-76页

作者：陈家坊蒋佩弦中国科学院土壤研究所

根据两年来水稻丰产的研究结果,在水稻所需的氮磷钾营养元素中,氮素最为活跃,而且敏锐地受到人为措施的影响。水稻的氮素营养问题,不仅在于氮素的供应容量,土壤的氮素供应强度及其持续时间,也同时深刻地影响水稻器管的协调生长。影响土... 详细信息

根据两年来水稻丰产的研究结果,在水稻所需的氮磷钾营养元素中,氮素最为活跃,而且敏锐地受到人为措施的影响。水稻的氮素营养问题,不仅在于氮素的供应容量,土壤的氮素供应强度及其持续时间,也同时深刻地影响水稻器管的协调生长。影响土壤氮素供应状况的因子是相当复杂的,除土壤中有机态氮存在的状态和本性以及矿化条

关键词：吸附特性陈家坊方程式溶液浓度方程平衡常数吸附量稻田土壤耕作土壤水稻土等温吸附方程

Halogen composition and heterogeneity in the continental lithospheric mantle

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science china Earth Sciences 2025年第1期68卷 310-314页

作者： chunfei chen State Key Laboratory of Geological Processes and Mineral Resources School of Earth Sciences China University of Geosciences

1. Introduction Halogens, including fluorine(f), chlorine(cl), bromine(Br), and iodine(I), are highly mobile and water-soluble elements that can become significantly enriched in melts and fluids. In fluids and melts, halogens react with nearly all metals and readily form complexes with metal cations, significantly influencing the distribution of metal elements between different phases. Therefore, halogens play a crucial role in the migration, enrichment, and mineralization of key metals in the lithosphere(Weis et al., 2012; Liu et al., 2024).

关键词：

同方期刊数据库