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Elimination of Quench cracking by controlling Agitation Uniformity

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材料热处理学报 2004年第5期25卷 457-461页

作者： cANALE Lauralice c.f TOTTEN George E Departamento de Materials Automobilistica e Aerondutica da EESC da Universidade de Sao Paulo - USP Sao Carlos SP BrazilPortland State University USA

Uniform agitation of the quenchant is a critically important control parameter in optimizing distortion control and reducing steel cracking. Quenching with ultrasonic agitation or in the presence of electrical and magnetic.fields provide uniform agitation leading to improved uniformity of the stress fields within the metal not readily achievable with more traditional agitation methods such as propeller pumps and sprays. These methods provide the additional potential advantage of varying agitation throughout the cooling cycle to achieve a wide range of cooling profiles not readily achievable with quenchants and more traditional agitation systems currently in use.

关键词：热处理淬火裂纹搅拌均匀性超声搅拌

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORfBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORfBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORfBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Loss of cD103^+ intestinal dendritic cells during colonic inflammation

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World Journal of Gastroenterology 2010年第1期16卷 21-29页

作者： Ulrike G Strauch Nicole Grunwald florian Obermeier Sonja Gürster Heiko c Rath Department of Internal Medicine I University of Regensburg

AIM:To investigate possible differences in dendritic cells(Dc)within intestinal tissue of mice before and after induction of colitis. METHODS:Mucosal Dc derived from intestinal tissue,as well as from mesenteric lymph nodes and spleen,were analyzed by fluorescence activated cell sorting(fAcS) *** of these cells were analyzed for secretion of different pro-and anti-inflammatory cytokines. Immunohistochemistry and immunofluorescence were performed on cryosections of mucosal tissue derived from animals with colitis as well as from healthy mice. RESULTS:It was shown that Dc derived from healthy intestinal lamina propria(LP)represented an immature phenotype as characterized by low-level expression of costimulatory *** contrast to Dc.from spleen and mesenteric lymph nodes(MLN)that secreted proinflammatory cytokines,LP-Dc produced high levels of the anti-inflammatory cytokine *** induction of mu-rine colitis in a cD4 + cD62L + transfer model or in chronic Dextran sulfate sodium-colitis,a marked increase of activated cD80 + Dc could be observed within the inflamed colonic ***,in contrast to splenic Dc,a significant population of Dc within MLN and colonic LP expressed the mucosal integrin cD103 which was lost during colitis. cONcLUSION:The constitutive secretion of antiinflammatory cytokines by immature Dc within the intestinal LP might regulate the homeostatic balance between mucosal immunity and ***103 + Dc could mediate this important function.

关键词： Dendritic cell colitis cytokines Integrin cD103

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

A new experimental setup to measure magnetic and optical properties of mass selected embedded metal clusters

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A new experimental setup to measure magnetic and optical pro...

Multiple sclerosis is at a checkpoint: advancing the program

Ⅻ International Symposium on Small Particles and Inorganic clusters

作者： M.Hillenkamp G.diDomenicantonio c.félix Institut de Physique des Nanostructures （IPN） Ecole Polytechnique fédérale de Lausanne （EPfL） cH-1015 Lausanne Switzerland Institut de Physique des Nanostructures （IPN） Ecole Polytechnique fédérale de Lausanne （EPfL） cH-1015 Lausanne Switzerland Institut de Physique des Nanostructures （IPN） Ecole Polytechnique fédérale de Lausanne （EPfL） cH-1015 Lausanne Switzerland

＜正＞ A new experimental setup has been designed and implemented at EPfL in Lausanne/ Switzerland. The objective is to generate permanent samples of mass selected metal clusters in different matrices stable at ambient conditions. This will allow measurements of optical, electrical and magnetic properties of systems like:

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来源： cnki会议评论

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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《优选论中的音节》述评

当代语言学 2005年第3期7卷 268-273页

作者： c.féry van de Vijver 马秋武辛玲南开大学外国语学院天津300071

(The Syllable in Optimality Theory)是一本在优选论框架下研究音节理论的论文集,由c.féry和van de Vijver主编,剑桥大学出版社2003年出版.

关键词：《优选论中的音节》书评优选论音节理论语言学韵律结构语音配列

Genetic diversity of the hepatitis c virus: Impact and issues inthe antiviral therapy

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World Journal of Gastroenterology 2007年第17期13卷 2416-2426页

作者： H Le Guillou-Guillemette S Vallet c Gaudy-Graffin c Payan A Pivert A Goudeau f Lunel-fabiani Laboratory of Virology University Hospital of Angers France and Laboratory HIFI UPRES EA 3859 University of Angers France Department of Microbiology EA 3882 CHU Morvan University Hospital of Brest France Université francois Rabelais INSERM ERI 19 et CHRU de Tours Tours France

The hepatitis c Virus (HcV) presents a high degree of genetic variability which is explained by the combination of a lack of proof reading by the RNA dependant RNA polymerase and a high level of viral replication. The re- sulting genetic polymorphism defines a classification in clades, genotypes, subtypes, isolates and quasispecies. This diversity is known to reflect the range of responses to Interferon therapy. The genotype is one of the pre- dictive parameters currently used to define the antiviral treatment strategy and the chance of therapeutic suc- cess. Studies have also reported the potential impact of the viral genetic polymorphism in the outcome of antivi- ral therapy in patients infected by the same HcV geno- type. Both structural and non structural genomic regions of HcV have been suggested to be involved in the Inter- feron pathway and the resistance to antiviral therapy. In this review, we first detail the viral basis of HcV diversity. Then, the HcV genetic regions that may be implicated in resistance to therapy are described, with a focus on the structural region encoded by the E2 gene and the non- structural genes NS3, NS5A and NS5B. Both mechanisms of the Interferon resistance and of the new antiviral drugs are described in this review.

关键词： Hepatitis c virus Genetic diversity Therapyresistance E2 NS3 NSSA NSSB

Serological surveillance for SARS-coV-2 antibodies among students,faculty and staff within a large university system during the pandemic

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World Journal of Virology 2025年第1期14卷 99-107页

作者： Marcos G Pinheiro Gabriela G O Alves Maria Eduarda R conde Sofia L costa Regina c S Sant’Anna Isa M f Antunes Mônica c carneiro fabio S Ronzei Julia c Sc.ffo felipe R Pinheiro Lialyz S Andre Helvecio c Povoa Valéria T Baltar fabíola Giordani Eduarda S Hemerly Gisele c Alexandre Karla c de Paula Márcio Watanabe Antonio claudio L da Nóbrega Jackeline christiane P Lobato fabio Aguiar-Alves Laboratory of Molecular Epidemiology and Biotechnology Rodolpho Albino University LaboratoryFluminense Federal UniversityNiterói 24241000Rio de JaneiroBrazil Estácio de SáUniversity Nova Friburgo 28611135Rio de JaneiroBrazil Pathology Program Medicine schoolFluminense Federal UniversityNiterói 24070090Rio de JaneiroBrazil Department of Pharmaceutical Sciences Lloyd L.Gregory School of PharmacyPalm Beach Atlantic UniversityWest Palm BeachFL 33401United States Health Institute of Nova friburgo Fluminense Federal UniversityNova Friburgo 28613001Rio de JaneiroBrazil Department of Epidemiology and Biostatistics Institute of Collective Health(ISC)Fluminense Federal UniversityNiterói 24033900Rio de JaneiroBrazil Institute of Physical Education Fluminense Federal UniversityNiterói 24020005Rio de JaneiroBrazil Department of Statistics Fluminense Federal UniversityNiterói 24210200Rio de JaneiroBrazil Department of Physiology and Pharmacology Fluminense Federal UniversityNiterói 24210130Rio de JaneiroBrazil

BAcKGROUND At the end of December 2019,the world faced severe acute respiratory syndrome-coronavirus 2(SARS-coV-2),which led to the outbreak of coronavirus disease 2019(cOVID-19),associated with respiratory *** virus has shown significant challenges,especially for senior citizens,patients with other underlying illnesses,or those with a sedentary *** tests conducted early on have helped identify how the virus is transmitted and how to curb its *** study hypothesis was that the rapid serological test for SARS-coV-2 antibodies could indicate the immunoreactive profile during the cOVID-19 pandemic in a university *** To conduct active surveillance for serological expression of anti-SARS-coV-2 antibodies in individuals within a university setting during the cOVID-19 *** This sectional study by convenience sampling was conducted in a large university in Niteroi-RJ,Brazil,from March 2021 to July *** study population consisted of students,faculty,and administrative staff employed by the university.A total of 3433 faculty members,60703 students,and 3812 administrative staff were invited to *** were gathered through rapid serological tests to detect immunoglobulin(Ig)M and IgG against ***χ²or fisher's exact test was used to conduct statistical analysis.A 0.20 significance level was adopted for variable selection in a multiple logistic regression model to evaluate *** A total of 1648 individuals were enrolled in the *** proportion of cOVID-19 positivity was 164/1648(9.8%).The adjusted logistic model indicate a positive association between the expression of IgM or IgG and age[odds ratio(OR)=1.16,95%cI:1.02-1.31](Pcontact with a cOVID-19-positive case(OR=3.49,95%cI:2.34-5.37)(Pceived the cOVID-19 vaccine(OR=2.33,95%cI:1.61-3.35)(Pcial isolation(OR=0.59,95%cI:0.41-0.84)(Pf sho

关键词： Serological surveillance SARS-coV-2 antibodies cOVID-19 Serological rapid test Risk factors for cOVID-19