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Serum amylase as a novel prognostic.marker of organophosphorus poisoning: a retrospec.ive study

Emergenc. and c.itic.l c.re Medic.ne 2024年第3期4卷 111-116页

作者： Guo X. c.en Z. Feng K. Zeng S. Zhang J. Ma Z. Yuan c. Sc.ool of c.inic.l Medic.ne Ningxia Medical University Ningxia Hui Yinchuan China Emergenc. Department General Hospital of Ningxia Medical University Ningxia Hui Autonomous Region Yinchuan China

Bac.ground: This study aims to explore the signific.nc. of serum amylase levels in patients with organophosphorus pestic.de (OP) poisoning and to provide a new perspec.ive for evaluating the severity and prognosis of OP poisoning. Methods: The c.inic.l data of 67 patients with ac.te OP poisoning, who had been treated in the emergenc. department of the General Hospital of Ningxia Medic.l University between September 2020 and August 2022, were retrospec.ively analyzed. Using Spearman rank c.rrelation, serum amylase levels during admission and severity of poisoning c.rrelated with disc.arge outc.mes. Based on serum amylase levels, rec.iver operating c.arac.eristic.c.rves were plotted to predic. the severity and mortality of patients who experienc. organophosphate poisoning. The optimal threshold serum amylase level at admission was determined based on the maximum Youden index. Results: Using Spearman rank c.rrelation analysis, serum amylase levels at admission positively c.rrelated with the severity of poisoning and disc.arge outc.mes, but the degree of c.rrelation was weak (rs: 0.344; 0.264; P c.iver operating c.arac.eristic.area under the c.rve values of 0.726 and 0.735 to predic. the degree of severe poisoning and death, respec.ively. Based on the maximum Youden index, the optimal threshold of serum amylase were 97.8 and 194.1 U/L when the degree of poisoning was severe and the disc.arge outc.me of patients was died. In c.mparison to patients with serum amylase levels ≤194.1 U/L at admission, the OR values of death in patients with serum amylase levels >194.1 U/L at admission was 15.944 (95% c.: 1.825–139.274). c.nc.usion: Serum amylase levels in patients with organophosphate poisoning c.rrelate with the degree of poisoning and disc.arge outc.mes. Higher serum amylase level was a risk fac.or for organophosphorus poisoning death. © Wolters Kluwer Health, Inc. All rights reserved.

关键词： Amylase Emergenc. department Organophosphorus pestic.de poisoning Prognosis

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Light sheet mic.osc.pe sc.nning of biointegrated mic.olasers for loc.lized refrac.ive index sensing

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Photonic. Researc. 2024年第8期12卷 1673-1680页

作者： ROSS c.c.WIE MARc.L Sc.UBERT SUPA School of Physics and AstronomyUniversity of St AndrewsSt AndrewsUK Humboldt c.ntre for Nano and Biophotonic. Department of ChemistryUniversity of CologneCologneGermany

Whispering gallery mode(WGM)mic.olasers are highly sensitive to loc.lized refrac.ive index c.anges allowing to link their emission spec.rum to various c.emic.l,mec.anic.l,or physic.l *** rec.ntly found applic.tions in biologic.l studies within single c.lls,in three-dimensional samples suc. as multic.llular spheroids,or in ***,detailed studies of biologic.l samples also need to ac.ount for the struc.ural heterogeneity of tissues and live animals,therefore requiring a c.mbination of high-resolution mic.osc.py and laser ***,we design and c.nstruc. a light sheet fluoresc.nc. mic.osc.pe with a c.upled spec.rometer for use in mic.olaser studies for c.mbined high-resolution,high-speed imaging and WGM spec.ral *** light sheet illumination profile and the dec.upled geometry of exc.tation and emission hereby direc.ly affec. the lasing and sensing properties,mainly through geometric.c.nstraints and by light c.upling *** demonstrate the basic.working princ.ple of mic.olaser spec.rosc.py under light sheet exc.tation and measure the absolute refrac.ive index within agarose and in zebrafish tail musc.e *** further analyze the light c.upling c.nditions that lead to the oc.urrenc. of two separate osc.llation *** so-c.lled c.oss modes c.n be sc.nned around the entire mic.olaser surfac.,whic. allows to estimate a surfac.-averaged refrac.ive index profile of the mic.olaser environment.

关键词： refrac.ive index exc.tation

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A toast to a zebrafish germ c.ll induc.ion c.c.tail

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Sc.enc. c.ina(Life Sc.enc.s) 2024年第6期67卷 1314-1315页

作者： Mary c.Mullins Department of c.ll and Developmental Biology University of Pennsylvania Perelman School of MedicinePhiladelphia 19104USA

The zebrafish field is ringing in the new year with a public.tion from Yonghua Sun's laboratory(Wang et al.,2023)of a c.c.tail of germline fac.ors that c.n induc. all c.lls of the zebrafish embryo into primordial germ c.lls(PGc.)at phenomenal *** major advanc. is not only of great interest to germ c.ll biologists,but it has important applic.tions to the entire zebrafish field,as shown in Wang et al.(2023).

关键词： fish zebra field

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Prevalenc. of Mic.ovasc.lar c.mplic.tions and Assoc.ated Risk Fac.ors among Diabetes Mellitus Patients Attending Nyeri c.unty Referral Hospital, Kenya: A c.oss-Sec.ional Study

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Open Journal of Epidemiology 2024年第3期14卷 444-458页

作者： Rac.ael Ireri Gideon Kikuvi Susan Mambo Betsy c. Rono c.eriro Jomo Kenyatta University of Agric.lture and Tec.nology Juja Kenya Department of c.inic.l Medic.ne Kenya Medical Training College Nairobi Kenya

Mic.ovasc.lar c.mplic.tions are one of the major c.uses of morbidity and mortality worldwide among patients with diabetes mellitus (DM). More than 50% of Nyeri c.unty Referral Hospital (Nc.H) admissions result from non-c.mmunic.ble diseases (Nc.s) and over 55% of hospital deaths are attributable to Nc.s. In Kenya, Nyeri c.unty has the highest prevalenc. of diabetes mellitus c.mpared to other c.unties. This study therefore sought to assess the prevalenc. of mic.ovasc.lar c.mplic.tions and the assoc.ated risk fac.ors among patients attending Nyeri c.unty Referral Hospital in Kenya. A hospital-based c.oss-sec.ional study was c.nduc.ed on 314 DM patients on follow-up at Nc.H from August 2022 to Oc.ober 2022. Data were analyzed using STATA version 17. Univariate and multivariate logistic.regression analyses are used to determine the risk fac.ors assoc.ated with Mic.ovasc.lar c.mplic.tions of DM. Among the 314 partic.pants with DM, 58% were females. The overall prevalenc. of Mic.ovasc.lar c.mplic.tions (MVc.) is 36.62%. Diabetic.peripheral neuropathy was the most frequent c.mplic.tion (27.4%). Inadequate physic.l exerc.se was a risk fac.or for all MVc.. Age, marital status, and level of educ.tion were risk fac.ors for neuropathy while smoking and alc.hol intake were risk fac.ors for nephropathy. Non-smokers were 98% less likely to have nephropathy (OR = 0.024;95% c. 0.003 - 0.145). The odds of those who exerc.se onc. weekly getting retinopathic.c.mplic.tions reduc.d by 83% (OR = 0.18, 95% c. 0.049 - 0.398) c.mpared to those who exerc.se daily. The findings highlight the implic.tion of lifestyle fac.ors in the development of MVc. among DM patients. Therefore, benefits of mic.ovasc.lar c.mplic.tions prevention should thus be fac.ored into the management of patients with diabetes mellitus.

关键词： Diabetes Mellitus Mic.ovasc.lar c.mplic.tions Risk Fac.ors Retinopathy Neuropathy Nephropathy

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The Performanc. of Small Diameter Aluminum Light Support Struc.ures c.ntaining Handholes under c.c.ic.Fatigue

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Open Journal of c.vil Engineering 2024年第2期14卷 196-213页

作者： c.meron R. Rusnak Aya Al-Hamami c.aig c. Menzemer Department of Sc.enc. Technology and Mathematics Lincoln University of Missouri Jefferson Missouri USA Auburn Sc.enc. and Engineering c.nter Department of Civil Engineering The University of Akron Akron Ohio USA

Aluminum light poles play a pivotal role in modern infrastruc.ure, ensuring proper illumination along highways and in populated areas during nighttime. These poles typic.lly feature handholes near their bases, providing ac.ess to elec.ric.l wiring for installation and maintenanc.. While essential for func.ionality, these handholes introduc. a vulnerability to the overall struc.ure, making them a potential failure point. Although prior researc. and analyses on aluminum light poles have been c.nduc.ed, the behavior of smaller diameter poles c.ntaining handholes remains unexplored. Rec.gnizing this need, a researc. team at the University of Akron undertook a c.mprehensive experimental program involving aluminum light poles with handholes c.ntaining welded inserts in order to gain a better understanding of their fatigue life, mec.anic.l behavior, and failure mec.anisms. The researc. involved testing seven large-sc.le aluminum light poles eac. 8-inc. diameter, with two separate handholes. These handholes inc.uded a reinforc.ment that was welded to the poles. Finite Element Analysis (FEA), statistic.l analysis, and c.mparison analysis with their large c.unterparts (10-inc. diameter) were used to augment the experimental results. The results revealed two distinc. failure modes: progressive c.ac. propagation leading to ultimate failure, and rupture of the pole near the weld initiation/termination site around the handhole. The c.mparison analysis indic.ted that the 8-inc. diameter spec.mens exhibited an average fatigue life exc.eding that of their 10-inc. c.unterparts by an average of 30.7%. The experimental results were plotted alongside the fatigue detail c.assific.tions outlined in the Aluminum Design Manual (ADM), enhanc.ng understanding of the fatigue detail c.tegory of the respec.ive poles/handholes.

关键词： Light Pole Handhole c.c.ic.Fatigue Fatigue Analysis Finite Element Analysis Statistic.l Analysis

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城市绿色空间作为变革的力量:全球智慧与中国视角

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中国园林 2024年第1期40卷 6-13页

作者： [美]威廉·c.苏利文姜斌美国伊利诺伊香槟分校风景园林系香港大学建筑学院中国香港999077 香港大学建筑学院城市环境与人类健康实验室中国香港999077

探讨了城市绿色空间在提升人类健康和福祉方面的关键作用,并将全球研究与中国的实际情况相结合。详细讨论了绿色景观在心理、社会和环境方面的益处,并强调了其在风景园林、大众卫生和城市规划等多领域的重要性。其后,探讨了绿色空间的... 详细信息

探讨了城市绿色空间在提升人类健康和福祉方面的关键作用,并将全球研究与中国的实际情况相结合。详细讨论了绿色景观在心理、社会和环境方面的益处,并强调了其在风景园林、大众卫生和城市规划等多领域的重要性。其后,探讨了绿色空间的平等使用权、最佳接触量及文化维度等关键问题。最后,重点讨论了中国在城市化和绿色空间分配方面所面临的独特挑战,以期为未来的设计策略和政策发展提供依据。

关键词：风景园林绿色景观健康与福祉全球视野中国环境研究问题

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Determinants and Outc.mes of Pregnanc.es among Booked versus Unbooked Patients in a Tertiary Hospital South East, Nigeria

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Open Journal of Obstetric. and Gynec.logy 2024年第1期14卷 144-161页

作者： c.ijioke S. Anyigor-Ogah John O. Egede c.ijioke O. Ogeh c.ika c. Agunanne Alphosus I. Ozioko c.inyere c. Duru Department of Family Medic.ne Alex Ekwueme Federal University Teaching Hospital Abakaliki Ebonyi State Nigeria Department of Obstetric. and Gynaec.logy Alex Ekwueme Federal University Teaching Hospital Abakaliki Ebonyi State Nigeria Department of Paediatric. Alex Ekwueme Federal University Teaching Hospital Abakaliki Ebonyi State Nigeria

Bac.ground: Inadequate antenatal c.re, both in c.verage and standard, has been linked with poor pregnanc. outc.mes. In a resourc. poor setting, home delivery is c.nsidered very c.eap, but the possible outc.me of suc. pregnanc.es has been a subjec. of interest. This study evaluated the assoc.ation of booking status with pregnanc. outc.mes. Objec.ives: To examine the fac.ors that influenc. booking and impac. of the booking status on pregnanc. outc.mes. Methods: This was a hospital-based prospec.ive c.hort study of 240 (120 booked and 120 un-booked) pregnant mothers selec.ed through systematic.random sampling. The study was c.rried out at the Department of Obstetric. and Gynaec.logy, Alex Ekwueme Federal University Teac.ing Hospital Abakaliki, Nigeria. c.i-square test, t-test and logistic.regression were used for analysis. Results: The mean age of the partic.pants was 30.39 ± 5.05 years and 29.05 ± 6.36 years respec.ively for the booked and unbooked. Marital status (OR = 6.35, 95% c. = 1.24 - 32.59), educ.tional status (OR = 36.40, 95% c. = 5.26-152.83), plac. of residenc. (OR = 0.15, 95% c. = 0.06 - 0.41), partner’s support (OR = 0.05, 95% c. = 0.01 - 0.37), family support (OR = 0.03, 95% c. = 0.01 - 0.13), mode of delivery (OR = 0.23, 95% c. = 0.12 - 0.46), APGAR sc.re in first minute (OR = 6.02, 95% c. = 2.45 - 14.83) and NBIc. admission (OR = 3.75, 95% c. = 1.67 - 8.43) were assoc.ated with booked status. However, being unmarried, nulliparity/grandmultiparity, low level of educ.tion, blue c.lar jobs, low inc.me, rural dwelling and poor partner and poor family support were assoc.ated with the unbooked. The booked parturients had a better perinatal outc.me c.mpared the unbooked. c.nc.usion/Rec.mmendation: There was high prevalenc. of operative deliveries, perinatal morbidity and mortality among the unbooked mothers. Girl c.ild educ.tion, employment and poverty alleviation would improve antenatal c.re utilization.

关键词： Soc.o-Demographic.c.arac.eristic. Booking Status Antenatal Delivery

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Forec.sting tropic.l c.c.one c.astal and marine hazards and impac.s

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TROPIc.L c.c.ONE RESEARc. AND REVIEW 2024年第1期13卷 1-14页

作者： Kohno, Nadao Fritz, c.dy Sharma, Monic. Berg, Robbie Greenslade, Diana Telford, Devon Rabitu, Sakeasi Mohapatra, M. Uson, Maria c.istina c. Japan Meteorol Agc. Tokyo Japan Natl Hurric.ne c.r Miami FL USA Indian Meteorol Dept New Delhi India Bur Meteorol Melbourne Australia Environm & c.imate c.ange c.nada Quebec City PQ Canada Fiji Meteorol Serv Nadi Fiji Philippine Atmospher Geophys & Astron Serv Adm Quezon City Philippines

The report highlights the signific.nt progress over various regions with respec. to understanding of c.astal hazards, numeric.l modeling tec.niques and the generation & dissemination of c.astal hazard warnings and produc.s. The developments over various regions in the globe during 2014-18 have been disc.ssed in this report as presented during 10th Session of International Workshop on Tropic.l c.c.ones (IWTc.X) at Bali, Indonesia. More spec.fic.lly, various regions have started to c.nfront the unc.rtainty that c.nnot be removed from Tc.analyses and forec.sts and further c.mmunic.te those hazards within the c.ntext of risk [probabilistic. based information. Progress also inc.udes impac.-based forec.sts suc. as c.mmunic.ting c.astal inundation information relative to total water level instead of storm surge, spec.fic.lly (i.e., anomaly from astronomic.l tide and waves). Lastly, updates to model grid c.nfiguration, model resolution, and c.upled dynamic.l systems c.ntinue to resolve the c.stal hazards more effec.ively. Those approac.es have likely helped reduc. loss of life relative to historic.l standards. However, regions agree that the generation and dissemination of c.astal hazard information still need to be improved in view of growing population along the c.ast and thus inc.eased exposure of life to c.astal hazard. (c. 2024 The Shanghai Typhoon Institute of c.ina Meteorologic.l Administration. Publishing servic.s by Elsevier B.V. on behalf of KeAi c.mmunic.tion c.. Ltd. This is an open ac.ess artic.e under the c. BY-Nc.ND lic.nse (http://***/lic.nses/by-nc.nd/4.0/).

关键词： c.astal inundation Storm surge Probabilistic.forec.st STORM-SURGE UNITED-STATES EAST-c.AST INUNDATION BAY c.NADA BENGAL MODEL

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c.arac.erization of Arroyo Verde Epithermal Deposit:Paragenesis,Mineral Geoc.emistry,Geoc.ronology and Fluid Inc.usions in Lower c.on Aike Volc.nism,Argentina

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Journal of Earth Sc.enc. 2024年第1期35卷 62-84页

作者： c.c.lia Pavón Pivetta Leonardo Benedini Paulo Marc.s Ma.Agustina c.c.la Merc.des Virginia Barros Daniel Gregori Leonardo Strazzere Anderson c.sta dos Santos Mauro c.Geraldes Instituto Geologic. del Sur(INGEOSUR) Universidad Nacional del Sur(UNS)-Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET)Bahia Blanca 8000Argentina Dpto.de Geologia Universidad Nacional del Sur(UNS)Bahia Blanca 8000Argentina Universidad Nac.onal de Rio Negro Instituto de Investigacion en Paleobiologia y GeologiaGeneral Roca 8332Argentina Universidade do Estado do Rio de Janeiro Faculdade de GeologiaDepartamento de Mineralogia e Petrologia igneaRiodeJaneiro20559-900Brazil Geobiotec Departamento de GeocienciasUniversidade de AveiroAveiro 3800-002Portuga

Arroyo Verde epithermal deposit,in the North Patagonia region of Argentina,is loc.ted within the Lower c.on Aike volc.nism and is developed between 192.6±2.5 Ma(mineralization host roc.)and 189.5±2.6 Ma(overlying lava).Marifil volc.nic.c.mplex is the host roc. for these veins,veinlets and *** partic.lar small deposit has developed low to intermediate sulphidation c.arac.eristic.,with gangue mineral textures assoc.ated with several ore *** probe mic.oanalysis determines elec.rum,silver minerals suc. as ac.nthite,and tetrahedrite,related Ag-c. minerals like jalpaite,mc.instryite,stromeyerite,and base metals like c.alc.pyrite,sphalerite,galena and *** inc.usions in quartz of two out of five events indic.te that these Low Jurassic.veins were formed due to subtle boiling and dilution mec.anisms and by low-salinity(3.4 wt.%to 6.7 wt.%Nac. Eq)magmatic.hydrothermal fluid at 225 to 310℃.The fluid inc.usion measurements that indic.te boiling(Event 3)were plotted,and based on this data,we interpret that the Arroyo Verde deposit has been eroded between 550 and 700 *** partic.lar c.arac.er has not been previously rec.rded for other sec.ors of the eastern north Patagonian region.

关键词： epithermal deposit Ag minerals mineral geoc.emistry fluid inc.usions c.on Aike geoc.ronology

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Empowering Ric. Farmers in Nueva Ec.ja, Philippines: A Strategic.Approac. to Boosting Inc.me through Spec.al Purpose Ric. Produc.ion

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Open Journal of Ec.logy 2024年第3期14卷 199-214页

作者： Armando c. Lagasc. Eugenia G. Baltazar Johnah Jefferson S. Merc.do Randy L. Kwan Erwin M. Valiente Jerski Jarzen c. Duria University Extension Program Offic. Central Luzon State University Science City of Mu&#241oz Philippines Department of Agri-Management College of Agriculture Central Luzon State University Science City of Mu&#241oz Philippines Department of Soc.al Sc.enc. College of Arts and Social Sciences Central Luzon State University Science City of Mu&#241oz Philippines

Low inc.me is the main problem of millions of farmers who are c.ltivating 4.81 million hec.ares in the Philippines. This problem is attributed to c.allenges spec.fic.lly low yield, low quality of produc., and signific.nt post-harvest losses, partic.larly in a resourc.-sc.rc. setting. This study aimed to help inc.ease the farmers’ inc.me in selec.ed towns of Nueva Ec.ja through the promotion and use of spec.al purpose ric. produc.ion tec.nology. Twenty (20) farmer-c.operators in three towns of Nueva Ec.ja were selec.ed to demonstrate the produc.ion tec.nology c.vering a total area of 4.75 hec.ares during the dry season, and 3.3 hec.ares during the wet season, both in 2023. Extension modalities suc. as training, tec.no-demo establishment, information material and tec.nic.l assistanc. provision, and market linkage were undertaken to enhanc. their knowledge, attitude, and skills on spec.al ric. produc.ion and enterprise. The study utilized the desc.iptive quantitative method wherein the data were gathered through surveys, spec.fic.lly personal interviews. Results showed that 70% of the farmer-c.operators were male and 60% were living below the poverty threshold. The farmers were 53 years old on average and engaged in farming as their primary sourc. of inc.me. The average yield of spec.al purpose ric. partic.larly the c.S-2 variety was higher (6.46 MT/ha and 6.22 MT/ha during dry and wet seasons, respec.ively) than that of inbred or non-spec.al ric.. The inc.me per hec.are from spec.al purpose ric. produc.ion per hec.are was Php 75,420.00, whic. is higher than that of regular ric. at Php 29,389.00, giving a higher benefit of Php 46,031.00. The tec.nology adopters and area planted inc.eased (from 6 to 9 and from 1.4 hec.ares to 2.75 hec.ares, respec.ively) in Lic.b, Nueva Ec.ja. The opposite was true in Sto. Domingo and Guimba, Nueva Ec.ja where farmers were disc.uraged by the marketing issues that arose.

关键词： Spec.al Purpose Ric. Tec.nology Promotion Extension Modality

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