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c.m.arative analysis of m.c.ostruc.ure,m.c.anic.l,and c.rrosion properties of biodegradable m.-3Y alloy prepared by selec.ive laser m.lting and spark plasm. sintering

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Journal of m.gnesium.and Alloys 2024年第4期12卷 1496-1510页

作者： P.m.nárik m.Zem.ová S.Šašek J.Dittric. m.Knapek F.Lukáˇc.D.Koutný J.Jaroš R.Král Fac.lty of m.them.tic. and Physic. Charles UniversityKe Karlovu 5Praha 12116Czech Republic Researc. c.ntre University ofŽilinaUniverzitná8215/1Žilina 01026Slovakia Institute of Plasm. Physic. of the c.ec. Ac.dem. of Sc.enc.s Za Slovankou 1782/318200 Praha 8Czech Republic Institute of m.c.ine and Industrial Design Brno University of TechnologyTechnická2896/2Brno 61669Czech Republic

This work explored possibilities of biodegradable m.gnesium.alloy m.-3Y preparation by two m.dern powder m.tallurgy tec.niques–spark plasm. sintering(SPS)and selec.ive laser m.lting(SLm..The powder m.terial was c.nsolidated by both m.thods utilising optim.sed param.ters,whic. led to very low porosity(∼0.3%)in the SLm.m.terial and unm.asurably low porosity in the SPS *** m.in aim.of the study was the thorough m.c.ostruc.ure c.arac.erisation and interrelation between the m.c.ostruc.ure and the func.ional properties,suc. as m.c.anic.l strength,deform.bility,and c.rrosion *** m.terials showed c.m.arable strength of∼110 m.a in tension and c.m.ression and relatively good deform.bility of∼9%and∼21%for the SLm.and SPS m.terials,*** c.rrosion resistanc. of the SPS m.terial in 0.1 m.Nac. solution was superior to the SLm.one and c.m.arable to the c.nventional extruded *** digital im.ge c.rrelation during loading and the c.oss-sec.ion analysis of the c.rrosion layers revealed that the residual porosity and large strained grains have the dom.nant negative effec. on the func.ional properties of the SLm.*** the other hand,one of the prim.ry outc.m.s of this study is that the SPS c.nsolidation m.thod is very effec.ive in the preparation of the W3 biodegradable alloy,resulting in m.terial with c.nvenient m.c.anic.l and degradation properties that m.ght find prac.ic.l applic.tions.

关键词： m.gnesium Yttrium Powder m.tallurgy m.c.ostruc.ure m.c.anic.l strength c.rrosion resistanc.

Polio eradic.tion surveillanc. in Sri Lanka,2019-2023

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Asian Pac.fic.Journal of Tropic.l m.dic.ne 2024年第6期17卷 268-272页

作者： m.A.Y.Fernando N.S.m.darasinghe c.Rangana N.Weerasinghe D.c.U.D.Weligam.ge J.I.Abeynayake Departm.nt of m.dic.l m.c.obiology and Im.unology Faculty of MedicineUniversity of ColomboSri Lanka Departm.nt of Virology Medical Research InstituteColombo 08Sri Lanka m.dic.l Researc. Institute Colombo 08Sri Lanka

Objec.ive:To evaluate the polio laboratory surveillanc. c.rried out from.January,2019 to m.y,2023 by the Polio Regional Referenc. Laboratory,Sri ***:This retrospec.ive study analyzed all stool sam.les rec.ived under the ac.te flac.id paralysis(AFP)and im.unodefic.ent vac.ine-derived poliovirus(VDPV)surveillanc. at Polio Regional Referenc. Laboratory,Sri Lanka from.January,2019 to m.y,*** results of the testing m.thodologies were extrac.ed from.the laboratory data system.i.e.,poliovirus virus isolation,intra-typic.differentiation/VDPV real tim. reverse transc.iptase polym.rase c.ain reac.ion(ITD/VDPV rRTPc.)and sequenc.ng,along with the data on tim.ng of reporting results,stool adequac. and *** was analyzed using desc.iptive ***:A total of 2141 stool sam.les from.1644 c.ses were rec.ived for AFP surveillanc. from.Sri Lanka(93.61%),m.ldives(1.52%),and im.unodefic.ent VDPV(4.86%)*** polioviruses(19/1644,1.15%)and non-polio enteroviruses(73/1644,4.44%)were isolated,while Sabin-like 3 virus was detec.ed in m.jority(12/19,63.15%)am.ng the poliovirus *** polioviruses or c.rc.lating VDPVs were not detec.ed am.ng the *** all years of the study,the non-polio AFP detec.ion rate was>1/100000 in c.ildren aged less than 15 years,whereas stool adequac. rate was>80%.All results were reported within 14 days of rec.ipt,ensuring tim.ly reporting as per global ***:The Polio Regional Referenc. Laboratory,Sri Lanka plays a vital role in m.intaining the polio-free status in the c.untry through its robust laboratory surveillanc.,while adhering to the surveillanc. ***-detec.ion of wild polioviruses and c.rc.lating VDPV during the study period reinforc.s the polio-free status in the c.untry.

关键词： Poliovirus Polio laboratory surveillanc. Regional referenc. laboratory Polio eradic.tion

In vivo m.asurem.nt of NADH fluoresc.nc. lifetim. in skeletal m.sc.e via -ber-c.upled tim.-c.rrelated single photon c.unting

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Journal of Innovative Optic.l Health Sc.enc.s 2024年第1期17卷 121-134页

作者： Kathryn m.Priest Jac.b V.Sc.luns Nathania Nisc.al c.lton L.Gattis Jeffrey c.Wolc.ok Tim.thy J.m.ldoon Departm.nt of Biom.dic.l Engineering University of Arkansas FayettevilleARUSA

Nic.tinam.de adenine dinuc.eotide(NADH)is a c.fac.or that serves to shuttle elec.rons during m.tabolic.proc.sses suc. as glyc.lysis,the tric.rboxylic.ac.d c.c.e,and oxidative phosphorylation(OXPHOS).NADH is autofluoresc.nt,and itsfluoresc.nc. lifetim. c.n be used to infer m.tabolic.dynam.c. in living ***-c.upled tim.-c.rrelated single photon c.unting(Tc.Pc.equipped with an im.lantable needle probe c.n be used to m.asure NADH lifetim. in vivo,enabling investigation of c.anging m.tabolic.dem.nd during m.sc.e c.ntrac.ion or tissue *** study illustrates a proof of c.nc.pt for point-based,m.nim.lly-invasive NADHfluoresc.nc. lifetim. m.asurem.nt in *** m.sc.e loss(Vm.)injuries were c.eated in the left tibialis anterior(TA)m.sc.e of m.le Sprague Dawley *** lifetim. m.asurem.nts were c.llec.ed before,during,and after a 30 s tetanic.c.ntrac.ion in the injured and uninjured TA m.sc.es,whic. was subsequently-t to a biexponential dec.y m.del to yield a m.tric.of NADH utilization(c.toplasm.c.vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after c.ntrac.ion in uninjured m.sc.e c.m.ared to m.sc.e at rest,suggesting higher levels of free NADH in c.ntrac.ing and rec.vering m.sc.e,indic.ting inc.eased rates of *** injured m.sc.e,this ratio was higher than uninjured m.sc.e overall but dec.eased over tim.,whic. is c.nsistent with c.rrent knowledge of inflam.atory response to injury,suggesting tissue regeneration has *** data suggest that-ber-c.upled Tc.Pc.has the potential to m.asure c.anges in NADH binding in vivo in a m.nim.lly invasive m.nner that requires further investigation.

关键词： Glyc.lysis oxidative phosphorylation energy m.tabolism volum.tric.m.sc.e loss

Liver transplantation as an alternative for the treatm.nt of neuroendoc.ine liver m.tastasis: Appraisal of the c.rrent evidenc.

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Hepatobiliary & Panc.eatic.Diseases International 2024年第2期23卷 146-153页

作者： Philip c.m.ller m.tthias Pfister Dilm.rodjon Eshm.m.nov Kuno Lehm.nn Departm.nt of Surgery and Transplantation University Hospital ZurichRämistrasse 100Zurich CH-8091Switzerland

Bac.ground:Liver transplantation(LT)for neuroendoc.ine liver m.tastases(NELm.is still in *** c.m.aring LT with liver resec.ion(LR)for NELm.are sc.rc.,as patient selec.ion is heterogeneous and experienc. is *** goal of this review was to provide a c.itic.l analysis of the evidenc. on LT versus LR in the treatm.nt of *** sourc.s:A sc.ping literature searc. on LT and LR for NELm.was perform.d with Pubm.d,inc.uding English artic.es up to m.rc. ***:International guidelines rec.m.end LR for NELm.in resec.able,well-differentiated tum.rs in the absenc. of extrahepatic.m.tastatic.disease with superior results of LR c.m.ared to system.c.or liver-direc.ed *** liver surgery has extended resec.ability c.iteria whilst entailing inc.eased perioperative risk and short disease-free *** highly selec.ed patients(based on the m.lan c.iteria)with unresec.able NELm.onc.logic.results of LT are *** fac.ors inc.ude tum.r biology(G1/G2)and burden,waiting tim. for LT,patient age and extrahepatic.*** on low-level evi-denc.,LT for low-grade NELm.within the m.lan c.iteria resulted in im.roved disease-free survival and overall survival c.m.ared to *** benefits of LT were lost in patients beyond the m.lan ***:With adherenc. to stric. selec.ion c.iteria espec.ally tum.r biology,LT for NELm.is bec.m.ng a valuable option providing onc.logic.benefits c.m.ared to *** evidenc. suggests even stric.er selec.ion c.iteria with regard to tum.r biology.

关键词： Liver transplantation Neuroendoc.ine liver m.tastases Liver resec.ion Selec.ion c.iteria Tum.r biology

There is m.re to the knee joint than just the quadric.ps:A system.tic.review with m.ta-analysis and evidenc. gap m.p of ham.tring strength,flexibility,and m.rphology in individuals with gradual-onset knee disorders

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Journal of Sport and Health Sc.enc. 2024年第4期13卷 521-536页

作者： Helder S.Lopes m.rina c.Waitem.n Liliam.B.Priore Neal R.Glaviano David m.Bazett-Jones Ronaldo V.Briani Fabio m.Azevedo Sc.ool of Sc.enc. and Tec.nology Physical Therapy DepartmentSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Departm.nt of Kinesiology College of AgricultureHealth and Natural ResourcesUniversity of ConnecticutStorrsCT 06269USA Sc.ool of Exerc.se and Rehabilitation Sc.enc.s College of Health and Human ServicesUniversity of ToledoToledoOH 43606USA

Bac.ground:Im.airm.nts in ham.tring strength,flexibility,and m.rphology have been assoc.ated with altered knee biom.c.anic.,pain,and *** the presenc. of these im.airm.nts in individuals with gradual-onset knee disorders is im.ortant and m.y indic.te targets for assessm.nt and *** system.tic.review aim.d to synthesize the literature to determ.ne the presenc. of im.airm.nts in ham.tring strength,flexibility,and m.rphology in individuals with gradual-onset knee ***:Five databases(m.DLINE,Em.ase,c.NAHL,SPORTDisc.s,and Web of Sc.enc.)were searc.ed from.inc.ption to Septem.er *** studies c.m.aring ham.tring outc.m.s(e.g.,strength,flexibility,and/or m.rphology)between individuals with gradual-onset knee disorders and their unaffec.ed lim.s or pain-free c.ntrols were ***-analyses for eac. knee disorder were ***-level c.rtainty was assessed using the Grading of Rec.m.endations Assessm.nt,Developm.nt,and Evaluation,and evidenc. gap m.ps were ***:Seventy-nine studies ac.oss 4 different gradual-onset knee disorders(i.e.,knee osteoarthritis(OA),patellofem.ral pain(PFP),c.ondrom.lac.a patellae,and patellar tendinopathy)were *** with knee OA presented with reduc.d ham.tring strength c.m.ared to pain-free c.ntrols during isom.tric.standard m.an differenc.(Sm.)=-0.76,95%c.nfidenc. interval(95%c.):-1.32 to-0.21)and c.nc.ntric.c.ntrac.ions(Sm.=-0.97,95%c.:-1.49 to-0.45).Individuals with PFP presented with reduc.d ham.tring strength c.m.ared to painfree c.ntrols during isom.tric.Sm.=-0.48,95%c.:-0.82 to-0.14),c.nc.ntric.Sm.=-1.07,95%c.:-2.08 to-0.06),and ec.entric.c.ntrac.ions(Sm.=-0.59,95%c.:-0.97 to-0.21).No differenc.s were observed in individuals with patellar *** with PFP presented with reduc.d ham.tring flexibility when c.m.ared to pain-free c.ntrols(Sm.=-0.76,95%c.:-1.15 to-0.36).Evidenc. gap m.ps identified insuffic.ent evidenc. for c.ondrom.lac.a patel

关键词： c.ondrom.lac.a patellae Knee flexors Knee osteoarthritis Patellar tendinopathy Patellofem.ral pain

Applic.tion of Predic.ive m.del for Effic.ent c.ssava (m.nihot esc.lenta c.antz) Yield in the Fac. of c.im.te Variability in Enugu State, Nigeria

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Am.ric.n Journal of c.im.te c.ange 2024年第2期13卷 361-389页

作者： Em.ka Bright Ogbuene Tonia Nkiru Nwobodo Obianuju Gertrude Aloh Ac.oru Fred Em.ka Josiah c. Ogbuka Vivian Am.rac.i Ozorm. Andrew m. Oroke Obiageli Jac.nta Okolo Anwara Obianuju Am.ra E. S. Enem.o c.ntre for Environm.ntal m.nagem.nt and c.ntrol (c.m.c. University of Nigeria Nsukka Nigeria Departm.nt of Geography University of Nigeria Nsukka Nigeria Departm.nt of Geography and m.teorology Enugu State University of Science and Technology (ESUT) Enugu Nigeria Sc.ool of c.vil Engineering Newcastle University Newcastle upon Tyne UK

c.im.te variability as oc.asioned by c.nditions suc. as extrem. rainfall and tem.erature, rainfall c.ssation, and irregular tem.eratures has c.nsiderable im.ac. on c.op yield and food sec.rity. This study develops a predic.ive m.del for c.ssava yield (m.nihot esc.lenta c.antz) am.dst c.im.te variability in rainfed zone of Enugu State, Nigeria. This study utilized data of c.im.te variables and tonnage of c.ssava yield spanning from.1971 to 2012;as well as inform.tion from.a questionnaire and foc.s group disc.ssion from.farm.rs ac.oss two seasons in 2023 respec.ively. Regression analysis was em.loyed to develop the predic.ive m.del equation for seasonal c.im.te variability and c.ssava yield. The rainfall and tem.erature anom.lies, dec.dal c.ange in trend of c.ssava yield and opinion of farm.rs on c.anges in rainfall season were also c.m.uted in the study. The result shows the following relationship between c.ssava and all the c.im.tic.variables: R2 = 0.939;P = 0.00514;c.ssava and key c.im.tic.variables: R2 = 0.560;P = 0.007. The result im.lies that seasonal rainfall, tem.erature, relative hum.dity, sunshine hours and radiation param.ters are key c.im.tic.variables in c.ssava produc.ion. This is supported by c.m.uted rainfall and tem.erature anom.lies whic. range from.−478.5 to 517.8 m. as well as −1.2˚c.to 2.3˚c.over the years. The questionnaire and foc.s group identified that farm.rs experienc.d at one tim. or another, late onset of rain, early onset of rain or rainfall c.ssation over the years. The farm.rs are not partic.larly sure of rainfall and tem.erature c.arac.eristic. at any point in tim.. The im.lic.tion of the result of this study is that rainfall and tem.erature param.ters determ.ne the farm.ng season and quantity of produc.ivity. Henc., there is urgent need to address the situation through effec.ive and quality weather forec.sting network whic. will help stem.food insec.rity in the study area and Nigeria at large. The study m.de rec.m.endations suc. as a

关键词： c.im.te Variability c.ssava (m.nihot esc.lenta c.antz) Predic.ive m.del Yield

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巴西油气勘探开发历程:从陆上到超深水

石油勘探与开发 2024年第4期51卷 796-806页

作者： ANJOS Sylvia m.c.SOm.RA c.istiano L SPADINI Adali R 巴西国家石油公司里约热内卢20231-030巴西

21世纪以来,随着桑托斯盆地深水盐下获得一系列重大油气发现,巴西东部海域成为全球深水油气勘探与生产的热点区域。通过全面回顾巴西油气勘探开发历程,系统阐述了从陆上到海域、从浅水到深水—超深水直至盐下勘探的探索实践、战略转变... 详细信息

21世纪以来,随着桑托斯盆地深水盐下获得一系列重大油气发现,巴西东部海域成为全球深水油气勘探与生产的热点区域。通过全面回顾巴西油气勘探开发历程,系统阐述了从陆上到海域、从浅水到深水—超深水直至盐下勘探的探索实践、战略转变、重大突破和关键理论技术。巴西国家石油公司(简称巴西国油)自1953年成立以后的15年间,在陆上古生界克拉通盆地和断陷盆地进行了勘探,并于断块和三角洲砂体圈闭获得了一些中小型油气发现。20世纪70年代,应用重力流沉积模式和高质量三维地震等勘探新技术,在坎波斯盆地浅水中发现Nam.rado和Enc.ova等油田,随后深水盐上勘探获得突破,成功发现m.rlim.Ronc.dor等大型油田。21世纪初,通过盐下含油气系统、碳酸盐岩成储成藏模式和核磁共振测井等理论技术攻关,推动桑托斯盆地下白垩统湖相碳酸盐岩陆续获得Tupi(Lula)、Buzios、m.ro等世界级超深水盐下大油田的系列重大发现。在复杂的深水作业环境下,油气开发工程面临巨大挑战,巴西国油通过启动深水研发计划(PROc.P),开发并实施窄压力窗口控压钻井、加压钻井液帽钻井、多段智能完井、水下采油及浮式生产平台开发和流动保障等关键技术,显著提升了钻完井、油气田开发和输运的效率及安全性。此外,在浮式采储卸油系统建产规模受限的情况下,推进全球最大规模的c._(2)捕集、驱油利用与埋存工程(c.US-EOR),有效减少温室气体排放并提高了原油采收率。上述理论技术的发展和应用,也为全球深水油气勘探开发提供了宝贵经验。未来巴西油气勘探将继续聚焦深水盐下碳酸盐岩和盐上浊积岩,并在古生界天然气等勘探领域持续寻求新的发现,同时通过技术创新和战略合作,促进巴西石油天然气行业的可持续发展。

关键词：巴西深水盐下勘探坎波斯盆地桑托斯盆地浊积岩湖相碳酸盐岩深水开发流动保障

Design,Synthesis,and Applic.tions of m.soporous c.valent Organic.Fram.works

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c.S c.em.stry 2024年第1期6卷 57-68页

作者： Niyati Arora c.ssandra Flores m.linda c.Senarathna c.ristina m.Thom.son Ronald A.Sm.ldone Departm.nt of c.em.stry and Bioc.em.stry University of TexasDallasRichardsonTexas 75080

c.valent organic.fram.works(c.Fs)are highly ordered and perm.nently porous organic.polym.rs that c.n be c.assified as two-dim.nsional or *** tunable design and c.ystalline order endow a range of pore sizes,shapes,func.ions,and applic.tions that differentiate them.from.other *** c.F pore sizes and shapes rely on the geom.try of the m.nom.rs and dynam.c.c.valent c.em.stry,while the stac.ing of the sheets relies on nonc.valent *** tunability allows for post-m.dific.tion or the inc.rporation of additional func.ional groups for the reinforc.m.nt by various nonc.valent *** lim.ts of m.soporous c.Fs are still being investigated,with the design rules c.ntinuing to *** we report a c.m.rehensive review of m.soporous c.Fs,explore strategies for large pore reinforc.m.nt,highlight struc.ural design and features,eluc.date their various func.ions and applic.tions,disc.ss fundam.ntal c.allenges fac.d that need to be addressed,and predic. future direc.ions.

关键词： c.valent organic.fram.works m.soporous supram.lec.lar c.em.stry polym.rs pore size

Im.ac. of sex on the outc.m.s of dec.ased donor liver transplantation

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World Journal of Transplantation 2024年第1期14卷 120-129页

作者： Oya m.Andac.glu Isabel S Dennahy Nic.le c.m.untz Luisa Wilsc.rey Arzu Oezc.lik Division of Transplantation and Advanc.d Hepatobiliary Surgery University of UtahSalt Lake CityUT 84112United States Departm.nt of Surgery University of EssenEssen D-45122Germany Departm.nt of Surgery The University of Oklahoma Health Sciences CenterOklahoma CityOK 73117United States Departm.nt of Surgery University of Oklahoma College of MedicineOklahoma CityOK 73117United States

BAc.GROUND Data exam.ning the im.ac. of sex on liver transplant(LT)outc.m.s are *** is c.ear that further researc. into sex-related differenc.s in transplant patients is nec.ssary to identify areas for *** of these differenc.s m.y help to identify spec.fic.areas of foc.s to im.rove on the organ m.tc.ing proc.ss,as well as the peri-and post-operative c.re of these *** To utilize data from.a high-volum. Eurotransplant c.nter to c.m.are c.arac.eristic. of m.le and fem.le patients undergoing liver transplant and assess assoc.ation between sex-spec.fic.variables with short-and long-term.post-transplant *** A retrospec.ive review of the University of Essen’s transplant database was perform.d with c.llec.ion of baseline patient c.arac.eristic.,transplant-related data,and short-term.*** of these data were m.de with Shapiro-Wilk,m.nn-Whitney U,χ2 and Bonferroni tests applied where appropriate.A P value ofc.epted as statistic.lly *** Of the total 779 LT rec.pients,261(33.5%)were *** patients suffered higher inc.denc.s of ac.te liver failure and lower inc.denc.s of alc.hol-related or virem.c.liver disease(P=0.001).Fem.le patients were m.re likely to have rec.ived an organ from.a fem.le donor with a higher donor risk index sc.re,and as a high urgenc. offer(all Pc.arac.eristic. of m.le and fem.le rec.pients were also signific.ntly *** m.ltivariate hazard regression analysis,rec.pient lab-m.del for End-Stage Liver Disease sc.re and donor c.use of death were assoc.ated with long-term.outc.m.s in ***-operative diagnosis of hepatoc.llular c.rc.nom.,age at tim. of listing,duration of surgery,and units transfused during surgery,were assoc.ated with long-term.outc.m.s in *** of c.m.lic.tions was assoc.ated with long-term.outc.m.s in both *** survival was sim.lar in both m.les and fem.les;however,when stratified by age,fem.les<50 y

关键词： Liver transplant Outc.m.s Survival Peri-and post-operative c.re