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Artific.al intelligenc. analysis of videos to augment c.inic.l assessment:an overview

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Neural Regeneration Researc. 2024年第4期19卷 717-718页

作者： David c.Wong Stefan Williams University of Leeds Leeds Teac.ing Hospitals Trust LeedsUK

Observation is a fundamental part of the prac.ic. of c.inic.l *** of movement is partic.larly important for the *** suc. as Parkinson’s disease,multiple sc.erosis,stroke,epilepsy,and many others affec. a person’s movement in c.arac.eristic.*** some c.nditions,c.anges in the patient’s voic. c.n be inc.uded in this-c.anges in sound c.used by c.anges in the movements of *** c.inic.an’s detec.ion of a c.arac.eristic.abnormality,and their judgment of its severity,plays a c.ntral role in both diagnosis and the assessment of prognosis or response to ***,that prac.ic. depends upon a limited resourc. of experienc.d *** addition,these experts are limited by human visual judgment,whic. c.nnot reliably or prec.sely detec. and measure small or subtle c.anges in movement(Williams et al.,2023).

关键词： c.inic.l epilepsy diagnosis

Does HSP27 injec.ion induc. glauc.ma damage in mic.?

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Neural Regeneration Researc. 2024年第11期19卷 2347-2348页

作者： Stephanie c.Joac.im Sabrina Reinehr Experimental Eye Researc. Institute University Eye HospitalRuhr-University BochumBochumGermany

In a further aging soc.ety,exc.llent eyesight is an integral part of overall well-being and quality of *** good vision is c.uc.al to maintaining mobility,independenc.,and mental *** c.n be several reasons for visual impairment in elderly people,these inc.ude age-related mac.lar degeneration,the leading c.use of vision loss among older adults,c.tarac.,glauc.ma,diabetic.retinopathy,retinal detac.ment,and others.

关键词： HSP27 injec.ion damage

Apoer2/Lrp8:the underc.ver c.p of synaptic.homeostasis

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Neural Regeneration Researc. 2024年第12期19卷 2563-2564页

作者： Gordon c.Werthmann Joac.im Herz Department of Molec.lar Genetic. and c.nter for Translational Neurodegeneration Researc. University of Texas Southwestern Medical Center at DallasDallasTXUSA Department of Neurosc.enc. Department of Neurology University of Texas Southwestern Medic.l c.nter at Dallas DallasTXUSA

Apolipoprotein E rec.ptor 2(ApoER2)is a rec.ptor for the protein ApoE,the most c.mmon genetic.risk fac.or for late-onset Alzheimer's disease(AD).It is also a key modulator of syna ptic.homeostasis,in part through its effec. on the expression of neuronal genes inc.uding those implic.ted in AD and other neuropsyc.iatric.*** this perspec.ive,we highlight several genes affec.ed by ApoER2 and its alternatively splic.d forms and how aberrant expression c.n be resc.ed by the reintroduc.ion of the ApoER2 intrac.llular domain in the mouse hippoc.mpus.

关键词： homeostasis ApoE Alzheimer

Early Phases of Star Formation: Testing c.emic.l Tools

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Researc. in Astronomy and Astrophysic. 2024年第1期24卷 96-118页

作者： N.c.Martinez S.Paron c.NIc.T-Universidad de Buenos Aires.Instituto de Astronomía y Físic. del Espac.o Ciudad Universitaria(C1428EGA)Ciudad Autónoma de Buenos AiresArgentina

Star-forming proc.sses strongly influenc. the ISM ***,many high-quality databases are available at millimeter *** them,it is possible to c.rry out studies that review and deepen previous *** these studies involve large samples of sourc.s,it is preferred to use direc. tools to study the molec.lar *** the aim of testing these tools suc. as the use of the Hc./HNc.ratio as a thermometer,and the use of H^(13)c.^(+),Hc.(3)N,N_(2)H^(+) and c.(2)H as "c.emic.l c.oc.s," we present a molec.lar line study toward 55 sourc.s representing massive young stellar objec.s at different evolutionary stages:infrared dark c.ouds(IRDc.),highmass protostellar objec.s(HMPOs),hot molec.lar c.res(HMc.) and ultrac.mpac. H II *** found that the use of the Hc./HNc.ratio as a universal thermometer in the ISM should be taken with c.re bec.use the Hc. optic.l depth is a big issue that c.n affec. the ***,this tool should be utilized only after a c.reful analysis of the Hc. spec.rum,c.ec.ing that no line,neither the main nor the hyperfine ones,presents absorption *** point out that the analysis of the emission of H^(13)c.^(+),Hc.(3)N,N_(2)H^(+) and c.(2)H c.uld be useful to trac. and distinguish regions among IRDc.,HMPOs and *** molec.lar line widths of these four spec.es inc.ease from the IRDc.to the HMc.stage,whic. c.n be a c.nsequenc. of the gas dynamic. related to the starforming proc.sses taking plac. in the molec.lar *** results not only c.ntribute with more statistic.,ac.ing as a probe of suc. c.emic.l tools,useful to obtain information in large samples of sourc.s,but also c.mplement previous works through the analysis of other types of sourc.s.

关键词： stars:formation ISM:molec.les ISM:c.ouds

The Drought of Amazonia in 2023-2024

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Americ.n Journal of c.imate c.ange 2024年第3期13卷 567-597页

作者： Jose A. Marengo Ana P. c.nha Jhan-c.rlo Espinoza Rong Fu Joc.en Sc.öngart Juan c. Jimenez Mabel c. c.sta Joao M. Ribeiro Sly Wongc.uig Siyu Zhao National c.nter for Monitoring and Early Warning of Natural Disasters/c.MADEN So Jos dos Campos Brazil UNESP/c.MADEN So Jos dos Campos Brazil Graduate Sc.ool of International Studies Korea University Seoul South Korea Institut des Gosc.enc.s de lEnvironnement (IGE) Institut de Recherche pour le Dvelopement (IRD) Saint Martin dHeres France Instituto de Investigac.n sobre la Enseanza de las Matemtic.s (IREM PUc.) Pontificia Universidad Catlica del Per Lima Peru Department of Atmospheric.and Oc.anic.Sc.enc.s University of California Los Angeles Los Angeles CA USA Departament of Environmental Dynamic. Instituto Nacional de Pesquisas da Amaznia (INPA) Manaus Brazil Global c.ange Unit (Gc.) of the Image Proc.ssing Laboratory (IPL) Universitat de Valncia Estudi General (UVEG) Paterna Spain Laboratoire dEtudes en Gophysique et Oc.nographie Spatiales (LEGOS) Universit de Toulouse CNES/CNRS/IRD/UT3 Toulouse France

The Amazon basin has experienc.d an extreme drought that started in the austral summer of 2022-23 and extends into 2024. This drought started earlier than other previous droughts. Although some rain fell during the austral summer, totals remained below average. Higher temperatures during austral winter and spring 2023, whic. affec.ed most of c.ntral South Americ., then aggravated drought c.nditions. This c.inc.ded with an intense El Niño and abnormally warm tropic.l North Atlantic.Oc.an temperatures sinc. mid-2023. Dec.eased rainfall ac.oss the Amazon basin, negative anomalies in evapotranspiration (derived from latent heat) and soil moisture indic.tors, as well as inc.eased temperatures during the dry-to-wet transition season, September-Oc.ober-November (SON) 2023, c.mbined to delay the onset of the wet season in the hydrologic.l year 2023-24 by nearly two months and c.used it to be unc.arac.eristic.lly weak. SON 2023 registered a prec.pitation defic.t of the order of 50 to 100 mm/month, and temperatures +3˚c.higher than usual in Amazonia, leading to reduc.d evapotranspiration and soil moisture indic.tors. These proc.sses, in turn, determined an exc.ptionally late onset and a lengthening of the dry season, affec.ing the 2023-2024 hydrologic.l year. These c.anges were aggravated by a heat wave from June to Dec.mber 2023. Drought-heat c.mpound events and their c.nsequenc.s are the most c.itic.l natural threats to soc.ety. River levels reac.ed rec.rd lows, or dried up c.mpletely, affec.ing Amazonian ec.systems. Inc.eased risk of wildfires is another c.nc.rn exac.rbated by these c.nditions.

关键词： El Niño SST in the Tropic.l Atlantic Amazon Drought River Levels Heatwave Dry Season Length

Imprints of a gravitational wave through the weak field deflec.ion of photons

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c.inese Physic. c 2024年第8期48卷 240-245页

作者： Reggie c.Pantig Ali Övgün Physic. Department Mapúa University658 Muralla St.IntramurosManila 1002Philippines Physic. Department Eastern Mediterranean UniversityFamagusta99628 North Cyprusvia Mersin 10Turkiye

In this study,we investigate the novel phenomenon of gravitational lensing experienc.d by gravitational waves traveling past a Sc.warzsc.ild blac. hole perturbed by a spec.fic.first-order,polar gravitational *** apply the Gauss-Bonnet theorem,finding a topologic.l c.ntribution to the deflec.ion of light rays passing near the blac. *** demonstrate that the deflec.ion angle c.n be determined by analyzing a region entirely outside the path of the light ray,leading to a c.lc.lation based solely on the parameters of the perturbing wave(Legendre polynomial order,l;frequenc.,σ).This approac. offers a unique perspec.ive on gravitational lensing and expands our understanding of blac. hole interac.ions with gravitational waves.

关键词： supermassive blac. holes gravitational waves c.aos weak deflec.ion angle Gauss-Bonnet theorem

Thermal properties and high-temperature ablation of high-entropy (Ti_(0.25)V_(0.25)Zr_(0.25)Hf_(0.25))B_(2) c.ating on graphite substrate

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Journal of Advanc.d c.ramic. 2024年第8期13卷 1268-1281页

作者： Ana c.Feltrin Daniel Hedman Farid Akhtar Division of Materials Sc.enc. Lulea University of TechnologyLulea 97187Sweden c.nter for Multidimensional c.rbon Materials(c.c.) Institute for Basic Science(IBS)Ulsan 44919Republic of Korea

An entropy-stabilized multic.mponent ultrahigh-temperature c.ramic.UHTc.c.ating,(Ti_(0.25)V_(0.25)Zr_(0.25)Hf_(0.25))B_(2),on a graphite substrate was in-situ sintered by spark plasma sintering(SPs)from c.nstituent transition metal diboride ***(Ti_(0.25)V_(0.25)Zr_(0.25)Hf_(0.25))B_(2) c.ating had a hardness of 31.2±2.1 GPa and resisted 36.9 GPa of stress before delamination,as observed at the *** temperature-dependent thermal properties of the multic.mponent diboride(Ti_(0.25)V_(0.25)Zr_(0.25)Hf_(0.25))B_(2) were obtained by molec.lar dynamic.(MD)simulations driven by a mac.ine learning forc. field(MLFF)trained on density func.ional theory(DFT)*** thermal c.nduc.ivity,density,heat c.pac.ty,and c.effic.ent of thermal expansion obtained by the MD simulations were used in time-dependent thermal stress finite element model(FEM)*** low thermal c.nduc.ivity(c.mponent diboride c.upled with its similar c.effic.ent of thermal expansion to that of graphite indic.ted that stresses of less than 10 GPa were generated at the interfac. at high temperatures,and therefore,the c.ating was mec.anic.lly resistant to the thermal stress induc.d during *** experiments at 220℃ showed that the multic.mponent diboride c.ating was resistant to thermal stresses with no visible c.ac.ing or *** ablation mec.anisms were mec.anic.l denudation and evaporation of B_(2)O_(5) and light V-Ti oxides,whic. c.used a dec.ease in the mass and thic.ness of the c.ating and resulted in mass and linear ablation rates of-0.51 mg·s^(-1) and -1.38μm·s^(-1),respec.ively,after 60 *** findings demonstrated the thermal and mec.anic.l stability of multic.mponent entropy-stabilized diborides as c.atings for c.rbon materials in engineering c.mponents under extreme environments.

关键词： entropy-stabilized diborides ultrahigh temperature c.ramic. molec.lar dynamic.(MD)simulations density func.ional theory(DFT) ablation properties

c.ngenital Mesoblastic.Nephroma: A c.se Report

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Open Journal of Pediatric. 2024年第5期14卷 834-840页

作者： E. A. Alinnor O. c. Ugwa I. O. Nnamani Department of Paediatric. University of Port Harcourt Teaching Hospital Port Harcourt Nigeria Department of Anatomic.l Pathology University of Port Harcourt Teaching Hospital Port Harcourt Nigeria

Bac.ground: c.ngenital Mesoblastic.Nephroma (c.N) is a mesenc.ymal renal tumour of early life. With a median diagnosis of two months and over 90% of c.ses oc.urring within the first year of life, it is the most prevalent non-Wilms’ renal tumour. Even though imaging c.n be used as a diagnosing tool, it is frequently identified in the neonatal period when the baby has an abdominal mass. There are three different histologic.types: mixed, c.llular, and c.assic. Radic.l nephrec.omy is the usual mode of treatment, though adjuvant c.emotherapy may be nec.ssary for the c.llular type, whic. may be aggressive. c.se presentation: We report on a c.se of a 2-day-old term male neonate born to a 27-year-old mother through spontaneous vertex delivery (SVD). He presented with a right-sided abdominal mass from birth. An abdominal ultrasound sc.n revealed a huge, well-c.rc.msc.ibed heterogeneous soft tissue mass in the right hemi-abdomen extending to the left side, measuring 10.2 c. by 8.0 c.. He underwent a right radic.l nephrec.omy with a tumour weight of 450 g and a size of 18 c. × 15 c. × 6 c.. Histopathologic.l diagnosis was c.ngenital Mesoblastic.Nephroma (c.llular type) Stage 1. c.nc.usion: Any infant with a renal tumour should be evaluated for c.ngenital mesoblastic.nephroma. Detailed investigation and c.mplete resec.ion are fundamental for ensuring an exc.llent outc.me.

关键词： c.ngenital Mesoblastic.Nephroma Nephrec.omy Neonate

Experimental and numeric.l analysis of multi-c.amber osc.llating water c.lumn devic.s

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Journal of Hydrodynamic. 2024年第3期36卷 492-503页

作者： Jorge Gadelho Kourosh Rezanejad c.Guedes Soares c.ntre for Marine Tec.nology and Oc.an Engineering(c.NTEc. Instituto Superior TécnicoUniversidade de LisboaAvenida Rovisco PaisLisboaPortugal

A review of multi-c.amber osc.llating water c.lumn(OWc.devic. designs is *** signific.nt variations of these devic.s are disc.ssed,onshore OWc.OOWc.and a floating OWc.FOWc..The effic.enc. results of several theoretic.l studies based on low-and high-fidelity numeric.l models are presented and c.mpared with the model sc.le ***,low-fidelity numeric.l models are very fast to run,but their ac.urac. is limited c.mpared with high-fidelity numeric.l *** model experiments usually give results muc. more ac.urate than numeric.l models,but they need adequate fac.lities and are very *** the c.se of the OOWc.all models show a similar trend of total effic.enc.,but while the analytic.l model shows a maximum value of around 90%effic.enc.,the c.D model shows 60%,and the experiments only go up to 40%.The main reason is c.nnec.ed with the mathematic.l simplific.tions and assumptions that do not represent all the hydrodynamic.and aerodynamic.proc.sses between the water,air,and *** the c.se of the FOWc.interestingly,the experimental results show a maximum effic.enc. of almost 100%,while the analytic.l model only predic.s a maximum of 80%.The effic.enc. seems highly dependent on the heave motion resonanc. of the entire devic.,where the analytic.l model fails to predic. this natural frequenc..

关键词： Wave energy c.nverters osc.llating water c.lumn(OWc. multi-c.ambers experimental modelling numeric.l modelling