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Microstructural evaluation and nanohardness of an AlcocucrFeNiTi high-entropy alloy

International Journal of Minerals,Metallurgy and Materials 2019年第5期26卷 634-641页

作者： c.D.Gómez-Esparza R.Peréz-Bustamante J.M.Alvarado-Orozco J.Mu?oz-Salda?a R.Martínez-Sánchez J.M.Olivares-Ramírez A.Duarte-Moller centro de Investigación en Materiales Avanzados (cIMAv) Laboratorio Nacional de Nanotecnología cONAcYT-corporación Mexicana de Investigación en Materiales S.A.de c.v.(cOMIMSA) centro de Ingeniería y Desarrollo Industrial Querétaro Campus centro de Investigación y de Estudios Avanzados del IPN Unidad Querétaro Universidad Tecnológica de San Juan del Río Escuela de Ingeniería civil Industrialy Mecánica Universidad De La Salle Bajío

An AlcocucrFeNiTi high-entropy alloy(HEA) was prepared by mechanical alloying and sintering to study the effect of Ti addition to the widely studied AlcocucrFeNi system. The structural and microstructural characteristics were investigated by X-ray diffraction(XRD), scanning electron microscopy(SEM), and transmission electron microscopy(TEM). The formation of four micrometric phases was detected: a cu-rich phase with a face-centered cubic(fcc) structure, a body-centered cubic(bcc) solid solution with cu-rich plate-like precipitates(fcc), an ordered bcc phase, and a tetragonal structure. The XRD patterns corroborate the presence of a mixture of bcc-, fcc-, and tetragonal-structured phases. The vickers hardness of the alloy under study was more than twice that of the AlcocucrFeNi alloy. Nanoindentation tests were performed to evaluate the mechanical response of the individual phases to elucidate the relationship between chemical composition, crystal structure, and mechanical performance of the multiphase microstructure of the AlcocucrFeNiTi HEA.

关键词： high-entropy alloys mechanical alloying microstructure nanoindentation

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Real-world disease activity and sociodemographic,clinical and treatment characteristics of moderate-to-severe inflammatory bowel disease in Brazil

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World Journal of Gastroenterology 2021年第2期27卷 208-223页

作者： cyrla Zaltman Rogério Serafim Parra Ligia Yukie Sassaki Genoile Oliveira Santana Maria de Lourdes Abreu Ferrari Sender J Miszputen Heda M B S Amarante Roberto Luiz Kaiser Junior cristina flores Wilson R catapani JoséMiguel Luz Parente Mauro Bafutto Odery Ramos carolina D Gonçalves Isabella Miranda Guimaraes Jose J R da Rocha Marley R Feitosa Omar Feres Rogerio Saad-Hossne Francisco Guilherme cancela Penna Pedro Ferrari Sales cunha Tarcia NF Gomes Rodrigo Bremer Nones Mikaell Alexandre Gouvea Faria Mírian Perpétua Palha Dias Parente António S Scotton Rosana Fusaro caratin Juliana Senra Júlio Maria chebli Department of Internal Medicine Federal University of Rio de JaneiroRio de Janeiro 21941-913Brazil Department of Surgery and Anatomy Ribeirão Preto Medical SchoolUniversity of São PauloRibeirao Preto 14049-900São PauloBrazil Department of Internal Medicine São Paulo State University(UNESP)Medical SchoolBotucatu 18618-687São PauloBrazil IBD Unit Federal University of BahiaSalvador 41150-000BahiaBrazil Department of clinical Medicine Medical SchoolUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Department of Gastroenterology Escola Paulista de MedicinaSão Paulo 04023-900Brazil Hospital de clinicas Universidade Federal do ParanaCuritiba 80060-900ParanaBrazil Department of Proctology Beneficencia Portuguesa Hospital/Kaiser Day HospitalSao Jose do Rio Preto 15015110São PauloBrazil Department of Gastroenterology and Hepatology Sciences Hospital de ClínicasUniversidade Federal do Rio Grande do SulPorto Alegre 90560002Rio Grande do SulBrazil Department of Gastroenterology Faculdade de Medicina do ABCSanto Andre 09060-870São PauloBrazil Department of General Medicine Gastroenterology UnitUniversity HospitalFederal University of PiauiTeresina 64049-550PiauíBrazil Department of Gastroenterology Faculdade de MedicinaUniversidade Federal de GoiásGoiania 74535-170GoiasBrazil Department of Surgery Botucatu Medical School at São Paulo State University(UNESP)Botucatu 18618687São PauloBrazil Department of Gastroenterology UNIFESPSão Paulo 04040-002Brazil IBD unit Gastroenterology DepartmentHospital Nossa Senhora das GraçasCuritiba 80810-040ParanaBrazil Department of Proctology Kaiser Hospital DiaSao Jose do Rio Preto 15015-110São PauloBrazil Health Sciences center Epidemiology UnitState University of PiauiTeresina 64001-280PiauíBrazil Department of Gastroenterology CMIP Centro Mineiro de PesquisaJuiz de Fora 36010-570Minas GeraisBrazil Scientific Affairs Takeda Pharmaceuticals BrazilSão Paulo 04709-011Brazil clinical Research Takeda Pharma

BAcKGROUND Understanding the treatment landscape of inflammatory bowel diseases(IBD)is essential for improving disease management and patient *** is the largest Latin American country,and it presents socioeconomic and health care differences across its geographical *** country has the highest increase in IBD incidence and prevalence in Latin America,but information about the clinical and treatment characteristics of IBD is *** To describe the sociodemographic,clinical,and treatment characteristics of IBD outpatients in Brazil overall and in the Southeast,South and Northeast/Midwest *** Multicenter,cross-sectional study with a 3-year retrospective chart review *** with moderate-to-severe crohn’s disease(cD)or ulcerative colitis(Uc)were consecutively enrolled between October 2016 and February *** cD at enrollment was defined as a Harvey Bradshaw Index≥8 or a cD Activity Index≥220 or a calprotectin level>200μg/g or an active result based on colonoscopy suggestive of inadequate control during the previous year;active Uc was defined as a partial Mayo score≥*** statistics were used to analyze all *** In a total of 407 included patients,cD was more frequent than Uc,both overall(264 cD/143 Uc patients)and by region(cD:Uc ratios of 2.1 in the Southeast,1.6 in the South and 1.2 in the Northeast/Midwest).The majority of patients were female(54.2%of cD;56.6%of Uc),and the mean ages were 45.9±13.8 years(cD)and 42.9±13.0 years(Uc).The median disease duration was 10.0(range:0.5-45)years for both IBD *** enrollment,44.7%[95%confidence interval(cI):38.7-50.7]of cD patients and 25.2%(95%cI:18.1-32.3)of Uc patients presented with active *** than 95%of IBD patients were receiving treatment at enrollment;cD patients were commonly treated with biologics(71.6%)and immunosuppressors(67.4%),and Uc patients were commonly treated with mesalazine[5-Aminosalicylic acid(5-ASA)]derivates(69.9%)and

关键词： Inflammatory bowel disease crohn's disease Ulcerative colitis Disease activity Epidemiology Treatment

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口服托伐普坦对收缩功能不全的心力衰竭患者左心室扩大及功能的影响:多中心、随机、双盲、安慰剂对照研究

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 58-58页

作者： Udelson J.E. McGrew F.A. flores E. 赵君 Division of cardiology Tufts-New England Medical Center/Tufts University School of Medicine Boston MA United States

目标:观察血管加压素v2受体拮抗剂托伐普坦对左心室(Lv)容积随时间变化的影响。背景:血管加压素水平在心力衰竭患者中可能升高,而且可能是心力衰竭进展的促进因素。方法:该研究为一项多中心、随机、双

关键词：托伐普坦心力衰竭功能不全安慰剂空白剂患者双盲

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cEPc Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai vipul Bairathi csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat varvara Batozskaya Subash chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-claude Brient Anastasiia Budzinskaya Masroor Bukhari vladimir Bytev Giacomo cacciapaglia Hua cai Wenyong cai Wujun cai Yijian cai Yizhou cai Yuchen cai Haiying cai Huacheng cai Lorenzo calibbi Junsong cang Guofu cao Jianshe cao Antoine chance Xuejun chang Yue chang Zhe chang Xinyuan chang Wei chao Auttakit chatrabhuti Yimin che Yuzhi che Bin chen Danping chen Fuqing chen Fusan chen Gang chen Guoming chen Hua-Xing chen Huirun chen Jinhui chen Ji-Yuan chen Kai chen Mali chen Mingjun chen Mingshui chen Ning chen Shanhong chen Shanzhen chen Shao-Long chen Shaomin chen Shiqiang chen Tianlu chen Wei chen Xiang chen Xiaoyu chen Xin chen Xun chen Xurong chen Ye chen Ying chen Yukai chen Zelin chen Zilin chen Gang chen Boping chen chunhui chen Hok chuen cheng Huajie cheng Shan cheng Tongguang cheng Yunlong chi Pietro chimenti Wen Han chiu Guk cho Ming-chung chu Xiaotong chu Ziliang chu Guglielmo coloretti Andreas crivellin Hanhua cui Xiaohao cui Zhaoyuan cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis christophe De La Taille Francesca De Mori chiara De Sio Elisa Del core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing computational Science Research center Beijing Beijing conveyi LTD Beijing Beijing Glass Research Institute co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech cairo University Giza center for Theory and computation National Tsing Hua UniversityHsinchu central china Normal University WuhanHubei central South University ChangshaHunan centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&Tv Equipment co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang University HangzhouZhejiang china Nuclear Instrument cO. LTDBeijing china University of Geosciences Beijing china University of Geosciences WuhanHubei china University of Mining and Technology XuzhouJiangsu china West Normal University NanchongSichuan chongqing University Department of PhysicsChongqing chulalongkorn University Bangkok city University of Hong Kong Department of PhysicsHong Kong cockcroft Institute Daresbury cornell University IthacaNY cPPM(AMU/IPhU&cNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china University Of Science And Technol

The circular Electron Positron collider(cEPc)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 Gev Linac,a 1.1 Gev Damping Ring,a Booster capable of achieving energies up to 180 Gev,and a collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton collider(SPPc).The cEPc primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the cEPc's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHc by an order of *** Technical Design Report(TDR)follows the Preliminary conceptual Design Report(Pre-cDR,2015)and the conceptual Design Report(cDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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