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Larval interference competition between the native Neotropical mosquito Limatus durhamii and the invasive Aedes aegypti improves the fitness of both species

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Insect Science 2018年第6期25卷 1102-1107页

作者： Stanislas Talaga Alain Dejean clémence Mouza Yves Dumont céline Leroy lnsUtut Pasteur de la Guyane Unitéd'Entomologie MédicaleCayenne cedexFrance cNRS UMR EcoFoGAgroParisTechCiradINRAUniversitédes AntillesUniversitéde GuyaneKourouFrance cNRS INPTUPSEcolabUniversitéde ToulouseToulouseFrance AMAP CIRADCNRSINRAIRDUniversit6MontpellierMontpellierFrance

Interspecific competition with native species during biological invasions can sometimes limit alien *** aimed to determine the potential ecological effects of Limatus durhamii Theobald 1901,a native Neotropical mosquito (Diptera:culicidae) species,on the invasive species Aedes (Stegomyia)aegypti (Linnaeus 1762)that breeds in the same artificial water *** time and adult dry mass were measured in 3 rearing conditions:control (a single larva),intraspecific competition (2 conspecific larvae),and interspecific competition (2 heterospecific larvae).Food was provided ad libitum to eliminate exploitative *** ***,development time was not affected by interspecific interference competition (nonsignificant differences with the control)and the adult dry mass was significantly higher,meaning that individual fitness likely ***,because previous studies showed longer development time and lighter adults during competition with other invasive mosquitoes,it is likely that *** can express a different phenotype depending on the competing *** similar pattern found for *** females and the nonsignificant difference with the control for males explain in part why this species can compete with ***.

关键词： Aedes aegypti increased fitness interference competition Limatus durhamii phenotypic plasticity resistance to invasion

Functionalization of Single- and Multi-Walled carbon Nanotubes with cationic Amphiphiles for Plasmid DNA complexation and Transfection

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Nano Research 2009年第8期2卷 638-647页

作者： cyrille Richard Nathalie Mignet céline Largeau Virginie Escriou Michel Bessodes Daniel Scherman Unitéde Pharmacologie chimique et Génétique CNRSUMR 8151ParisF-75270 cedex France INSERM U 640ParisF-75270 cedex France UniversitéParis Descartes Facultédes Sciences Pharmaceutiques et BiologiquesParisF-75270 cedex France ENScP ParisF-75231 cedex France

The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired ***,even although the effi ciency of non-viral transfection systems has improved in the last decade,none have yet proven to be suffi ciently effective in *** report herein our results on the functionalization of single-walled carbon nanotubes(SWNT)and multi-walled carbon nanotubes(MWNT)by two cationic amphiphiles(lipid RPR120535 and pyrenyl polyamine),their use for the complexation of plasmid DNA,and their efficiency in transfecting cells in *** experiments have shown that the efficiency of transfection is higher when using SWNT instead of MWNT,and that transfection effi ciency is similar or slightly higher when using nanoplexes(SWNT/lipid RPR120535/DNA)instead of lipoplexes(lipid RPR120535/DNA)and several orders of magnitude higher than that of naked *** study therefore shows both that the transfection is better when using SWNTs and that it is dependent on the nature of the amphiphilic molecules adsorbed on the nanotubes.

关键词： carbon nanotubes amphiphile gene delivery plasmid DNA in vitro

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDline,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

The contribution of microorganisms and metazoans to mineral nutrition in bromeliads

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Journal of Plant Ecology 2016年第3期9卷 241-255页

作者： céline Leroy Jean-François carrias Régis céréghino Bruno corbara IRD UMR AMAP(botAnique et Modélisation de l’Architecture des Plantes et des végétations)Boulevard de la LirondeTA A‐51/PS2F‐34398 Montpellier Cedex 5France UMR Ecologie des Forêts de Guyane(AgroParisTech CIRADCNRSINRAUniversitéde GuyaneUniversitédes Antilles)Campus AgronomiqueBP 316F-97379 Kourou cedexFrance Universitéclermont Auvergne UniversitéBlaise PascalBP 10448F-63000 Clermont-FerrandFrance cNRS UMR 6023Laboratoire Microorganismes:Génome et EnvironnementCampus Universitaire des Cézeaux1 impasse Amélie MuratTSA 60026 CS *** Aubière cedexFrance Universitéde Toulouse INPUPS EcoLab(Laboratoire Ecologie Fonctionnelle et Environnement)F-31062 ToulouseFrance cNRS EcoLab118 Route de NarbonneF-31062 ToulouseFrance

Aims One critical challenge for plants is to maintain an adequate nutrient supply under fluctuating environmental *** is particularly true for epiphytic species that have limited or no access to the pedosphere and often live in harsh *** have evolved key innovations such as epiphytism,water-absorbing leaf trichomes,tank habit and crassulacean acid metabolism(cAM)photosynthesis that enable them to survive under various environmental *** encompass diverse ecological types that live on different substrates(they can be terrestrial,epilithic or epiphytic)and vary in their ability to retain water(they can be tank-forming or tankless)and photosynthetic pathway(i.e.c3 or cAM).In this review,we outline the nutritional modes and specializations that enable bromeliads to thrive in a wide range of nutrient-poor(mostly nitrogen-depleted)*** FindingsBromeliads have evolved a great diversity of morphologies and functional adaptations leading to the existence of numerous nutritional *** on species that have absorptive foliar trichomes,we review evidence that bromeliads have evolved multi-faceted nutritional strategies to respond to fluctuations in the supply of natural nitrogen(N).These plants have developed mutualistic associations with many different and functionally diverse terrestrial and aquatic microorganisms and metazoans that contribute substantially to their mineral nutrition and,thus,their fitness and *** and fungal microbiota-assisted N provisioning,protocarnivory,digestive mutualisms and myrmecotrophic pathways are the main strategies used by bromeliads to acquire *** combination of different nutritional pathways in bromeliads represents an important adaptation enabling them to exploit nutrient-poor ***,as has been shown for several other vascular plants,multiple partners are involved in nutrient acquisition indicating that there have been convergent adap

关键词： digestive mutualism insect-assisted nutrients leafδ15N multiple N sources myrmecotrophy

computational Insights into charge Storage Mechanisms of Supercapacitors

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Energy & Environmental Materials 2020年第3期3卷 235-246页

作者： Kui Xu Hui Shao Zifeng Lin céline Merlet Guang Feng Jixin Zhu Patrice Simon Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing Tech University(NanjingTech)30 South Puzhu RoadNanjing 211816China cIRIMAT Universite de ToulouseCNRSUniversite Toulouse 3-Paul Sabatier118 Route de NarbonneToulouse cedex 931062France Reseausurle Stockage Electrochimique de l’Energie(RS2E) Federation de Recherche CNRS 3459HUB de l’EnergieRue BaudelocqueAmiens 80039France college of Materials Science and Engineering Sichuan UniversityNo.24 South Section 1Yihuan RoadChengdu 610065China State Key Laboratory of coal combustion School of Energy and Power EngineeringHuazhong University of Science and Technology(HUST)Wuhan 430074China Nano Interface centre for Energy School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan 430074China

computational modeling methods,including molecular dynamics(MD)and Monte carlo(Mc)simulations,and density functional theory(DFT),are receiving booming interests for exploring charge storage mechanisms of electrochemical energy storage *** methods can effectively be used to obtain molecular scale local information or provide clear explanations for novel experimental findings that cannot be directly interpreted through experimental *** short review is dedicated to emphasizing recent advances in computational simulation methods for exploring the charge storage mechanisms in typical nanoscale materials,such as nanoporous carbon materials,2 D MXene materials,and metal-organic framework *** a better understanding of charge storage mechanisms and experimental observations,fast and accurate enough models would be helpful to provide theoretical guidance and experimental basis for the design of new high-performance electrochemical energy storage devices.

关键词： 2D material charge storage mechanism molecular simulations porous electrode supercapacitor

Phosphorus Use Efficiency of Bio-Based Fertilizers:Bioavailability and Fractionation

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Pedosphere 2016年第3期26卷 310-325页

作者： céline VANEEcKHAUTE Joery JANDA Peter A.VANROLLEGHEM Filip M.G.TAcK Erik MEERS Laboratory for Analytical and Applied Ecochemistry Faculty of Bioscience EngineeringGhent University model EAU Département de Génie Civil et de Génie des EauxFaculté des Sciences et de GénieUniversité Laval

Although to date some technologies producing bio-based phosphorus(P) fertilizers have been proposed and implemented, the efficient use of the recovered products is still limited due to legislative constraints and lack of insights in the P release with time and in the corresponding mechanisms. The aim of this work was to evaluate the fertilizer performance in terms of P release and use efficiency of recovered struvite, FePO_4-sludge, digestate, and animal manure as compared to fossil reserve-based mineral triple superphosphate(TSP). First, product physicochemical characteristics and P fractions in the context of European fertilizer legislation were assessed. Next, a controlled greenhouse experiment was set up to evaluate plant reactions as well as changes of P availability in a sandy soil with high P status and a Rheinsand soil with low P status. Soil P fractions were determined in the extracts with water, ammonium lactate and cacl_2, and in soil solution sampled with Rhizon soil moisture samplers. Based on all results, it is worth conducting long-term field trials to evaluate the P release effect of struvite and digestate as compared to animal manure and TSP on different soil types with varying P status. These products showed promise as sustainable substitutes for conventional P fertilizers and could contribute to a more efficient use of P in agriculture. A refined classification of P application standards/recommendations in terms of soil P status, soil texture, and fertilizer characteristics, next to the crop P demand, is recommended. Moreover, the additional use of Rhizon samplers for determination of direct available P, including dissolved organic P, is proposed for better understanding and categorization of different P fertilizers in environmental and fertilizer legislations.

关键词： chemical soil analysis digestate nutrient recovery Rhizon samplers struvite

Recurrent clostridium difficile infections:The importance of the intestinal microbiota

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World Journal of Gastroenterology 2014年第23期20卷 7416-7423页

作者： Marie céline Zanella Terrier Martine Louis Simonet Philippe Bichard Jean Louis Frossard Service of General Internal Medicine Geneva University Hospital1211 GenevaSwitzerland Service of Gastroenterology and Hepatology Geneva University Hospital1211 GenevaSwitzerland

clostridium difficile infections(cDI)are a leading cause of antibiotic-associated and nosocomial *** effective antibiotic treatments,recurrent infections are *** the recent emergence of hypervirulent isolates of ***,cDI is a growing epidemic with higher rates of recurrence,increasing severity and *** microbiota transplantation(FMT)is an alternative treatment for recurrent cDI.A better understanding of intestinal microbiota and its role in cDI has opened the door to this promising therapeutic *** is thought to resolve dysbiosis by restoring gut microbiota diversity thereby breaking the cycle of recurrent *** the first reported use of FMT for recurrent cDI in 1958,systematic reviews of case series and case report have shown its effectiveness with high resolution rates compared to standard antibiotic *** article focuses on current guidelines for cDI treatment,the role of intestinal microbiota in cDI recurrence and current evidence about FMT efficacy,adverse effects and acceptability.

关键词： clostridium difficile infection clostridium difficile recurrence Fecal microbiota transplantation Stool transplantation Microbiota

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Evaluation of the colorectal cancer risk conferred by rare UNc5c alleles

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World Journal of Gastroenterology 2014年第1期20卷 204-213页

作者： Sébastien Küry céline Garrec Fabrice Airaud Flora Breheret Virginie Guibert cécile Frenard Shuo Jiao Dominique Bonneau Pascaline Berthet céline Bossard Olivier Ingster Estelle cauchin Stéphane Bezieau cHU Nantes Service de Génétique Médicale44093 Nantes CEDEX 1France Public Health Sciences Division Fred Hutchinson Cancer Research CenterSeattleWA 98109United States cHU Angers Service de Génétique Médicale4 rue Larrey49933 AngersFrance centre de Lutte contre le cancer Fran?ois Baclesse 3 avenue du Général Harris14076 Caen Cedex 5France Université de Nantes Faculté de Médecine de NantesEA 4273 NantesFrance cHU Nantes Institut des Maladies de l’Appareil Digestif et Service d’Hépato-Gastroentérologie44093 Nantes Cedex 1France

AIM: To evaluate the risk associated with variants of the UNc5c gene recently suspected to predispose to familial colorectal cancer (cRc).

关键词： colorectal cancer UNc5c Genetic predisposition Familial study Association study Low risk