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Journal of Renewable Materials 2020年第1期8卷 29-43页

作者： Maud chemin céline moreau Bernard cathala Ana Villares INRAE UR BIAF-44316NantesFrance

In this work,we studied the adsorption of modified cellulose nanocrystals onto solid surfaces by quartz crystal microbalance with dissipation monitoring(QcM-D).cellulose nanocrystals obtained from tunicate(cNc)were modified at reducing end by amidation *** different functionalities were investigated:a polyamine dendrimer(cNc-NH_(2)),which interacts with gold surface by the amine groups;and a biotin moiety(cNc-Biot),which has a strong affinity for the protein streptavidin(SAV).QcM-D results revealed different adsorption behaviors between modified and unmodified ***,unmodified cNcs covered almost all the surface forming a rigid and flat layer whereas reducing end modified cNcs remained rather upright forming a hydrated and viscoelastic layer with lower surface *** analysis of adsorption kinetics allowed the calculation of an apparent collision rate factor,which resulted 10-fold higher for unmodified cNcs compared to reducing end modified cNcs,therefore,demonstrating the different adsorption behavior.

关键词： cellulose nanocrystals amidation reducing-end modification Voight model collision rate efficiency factor rate constant

Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease

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Neural Regeneration Research 2025年第2期20卷 574-586页

作者： Olivier Kerdiles Méryl-Farelle Oye Mintsa Mi-mba Katherine coulombe cyntia Tremblay VincentÉmond Martine Saint-Pierre clémence Rouxel line Berthiaume Pierre Julien Francesca cicchetti Frédéric calon Facultéde pharmacie UniversitéLaval1050 Avenue de la MédecineQuebecQCCanada Axe Neuroscience Centre de recherche du CHU de Québec-UniversitéLaval(Pavillon CHUL)2705 Boulevard LaurierQuebecQCCanada Institute of Nutrition and Functional Foods QuebecQCCanada Optinutribrain International Associated Laboratory(NutriNeuro FranceINAFCanada)QuebecQCCanada Axe Endocrinologie et Néphrologie Centre de recherche du CHU de Québec-UniversitéLavalQuebecQCCanada Département de Médecine Facultéde MédecineUniversitéLavalQuebecQCCanada Département de Psychiatrie et Neurosciences Facultéde MédecineQuebecQCCanada

There is a need to develop interventions to slow or reverse the degeneration of dopamine neurons in Parkinson’s disease after *** that preclinical and clinical studies suggest benefits of dietary n-3 polyunsaturated fatty acids,such as docosahexaenoic acid,and exercise in Parkinson’s disease,we investigated whether both could synergistically interact to induce recovery of the dopaminergic ***,mice received a unilateral stereotactic injection of 6-hydroxydopamine into the striatum to establish an animal model of nigrostriatal *** weeks after lesion,animals were fed a docosahexaenoic acid-enriched or a control diet for the next 8 *** this period,the animals had access to a running wheel,which they could use or *** acid treatment,voluntary exercise,or the combination of both had no effect on(i)distance traveled in the open field test,(ii)the percentage of contraversive rotations in the apomorphine-induction test or(iii)the number of tyrosine-hydroxylase-positive cells in the substantia nigra pars ***,the docosahexaenoic acid diet increased the number of tyrosine-hydroxylase-positive terminals and induced a rise in dopamine concentrations in the lesioned *** to docosahexaenoic acid treatment or exercise alone,the combination of docosahexaenoic acid and exercise(i)improved forelimb balance in the stepping test,(ii)decreased the striatal DOPAc/dopamine ratio and(iii)led to increased dopamine transporter levels in the lesioned *** present results suggest that the combination of exercise and docosahexaenoic acid may act synergistically in the striatum of mice with a unilateral lesion of the dopaminergic system and provide support for clinical trials combining nutrition and physical exercise in the treatment of Parkinson’s disease.

关键词： 6-hydroxydopamine dopamine dopamine transporter exercise neurorestoration Parkinson’s disease polyunsaturated fatty acids omega-3

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Nucleoredoxin-like 2 metabolic signaling impairs its potential contribution to neurodegenerative diseases

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Neural Regeneration Research 2023年第3期18卷 529-530页

作者： Mariangela corsi céline Jaillard Thierry Léveillard Sorbonne Université INSERMCNRSInstitut de la VisionParisFrance

Alzheimer’s disease(AD)threatens the foundations of humanity and our *** is a neurological disorder primarily affecting the elderly through memory disorders,cognitive decline,and loss of *** dramatic consequences of this late-onset disease were illustrated sensitively in Michael Haneke’s masterpiece,*** and governments have invested colossal efforts to develop a treatment for this terrible *** and in the past decade the amyloid cascade has dominated the therapeutic research on AD,but the absence of benefit for patients treated with drugs that reduce brain amyloid deposit questions the role ofβ-amyloid as a causative agent(Herrup,2021).The recent approval of aducanumab by the United States Food and Drug Administration,a drug that targetsβ-amyloid,is at the center of a scandal among clinicians and researchers,as it does not provide therapeutic benefits to patients and is listed among the breakdowns of the year 2021 by Science magazine(Voosen et al.,2021).The lack of progress in curing AD and recent therapeutic failures calls for further exploratory research.

关键词： approval consequences listed

From research integrity to research relevance to advance forensic science

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Forensic Sciences Research 2021年第3期6卷 292-294页

作者： claude Roux céline Weyermann centre for Forensic Science University of Technology SydneySydneyAustralia Ecole des Sciences criminelles Universitéde LausanneLausanneSwitzerland

Research is essential for any field to move *** allows us to expand our body of knowledge and enables any discipline to advance its application and meet its overall *** is of course also essential for forensic science,a fundamentally research-based discipline,to develop and validate detection or examination methods and gather data and establish frameworks to understand forensic traces and their value to relevant stakeholders,such as law enforcement and the courts.

关键词： enable discipline forensic

A global analysis of the introduction pathways and characteristics associated with non-native fish species introduction, establishment, and impacts

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Ecological Processes 2024年第2期13卷 16-31页

作者： camille Bernery céline Bellard Franck courchamp Sébastien Brosse Boris Leroy cNRS Agro Paris Tech Ecologie Systématique Evolution Université Paris-Saclay Unité Biologie des Organismes et Ecosystèmes Aquatiques (BOREA UMR 8067) Muséum National d’Histoire Naturelle Sorbonne Universités Université de Caen Normandie Université des Antilles CNRS IRD Laboratoire évolution & Diversité Biologique (EDB UMR5174) Université Paul Sabatier-Toulouse 3 CNRS IRD UPS

Background The invasion success of introduced freshwater fishes is influenced by many factors, including ecological, species, and socioeconomic characteristics. Most studies that document the importance of these characteristics are conducted at local scales and/or focus on a single step of the invasion process. In this study, we aim to determine the species characteristics, ecological characteristics, and socioeconomic characteristics of non-native freshwater fish invasions. Our assessment was done at the global scale and considers all three steps of the invasion(i.e., introduction, establishment, and impact). For this purpose, we applied generalized linear models to 20 variables collected for 307 non-native species and modeled them as a function of ecological characteristics(i.e., environmental features), species traits(i.e., functional and morphological), and socioeconomic characteristics(i.e., human use and introduction pathways). We considered the number of countries in which each species was introduced, established, or had ecological impacts as a proxy of invasion step success. We also explored the specifics of species introduced through the aquaculture and the ornamental fish trade *** We found that non-native freshwater fishes with broad diets, high parental care, and multiple introduction pathways are the most widely introduced and established worldwide. The number of countries with impacts reported was best explained by the type of introduction pathway(i.e., aquaculture or fisheries). Moreover, among non-native species introduced through aquaculture, those belonging to cypriniformes and having broad diets were the most widely introduced and established species. In contrast, the species introduced through the ornamental fish trade pathway belonged to various taxonomic orders but were mainly native to tropical *** considering several types of factors is important when analyzing the invasion success of freshwater fish and disentang

关键词： Aquaculture Ecology Exotic Freshwater fish Introduction pathway Invasion step Morphology Ornamental fish trade Socioeconomic Trait

Self-assembly of colloidal polymers from two-patch silica nanoparticles

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Nano Research 2020年第12期13卷 3371-3376页

作者： Weiya Li Bin Liu céline Hubert Adeline Perro Etienne Duguet Serge Ravaine cNRS CRPPUMR 5031Univ.BordeauxPessac33600France cNRS ICMCBUMR 5026Univ.BordeauxPessac33600France cNRS Bordeaux INPISMUMR 5255Univ.BordeauxTalence33400France

We report the formation of colloidal polymers consisting of disk-like silica nanoparticles(NPs)with polystyrene(PS)chains at the bottom of their two cavities assembled through reduction of the solvent quality for the PS chains and linked by hydrophobic *** show that this NPs assembly exhibits a two-stage process involving reaction-controlled polymerization and diffusion-controlled *** polymer networks are produced by the incorporation of three-patch NPs,which serve as branching points between the colloidal *** co-assembling preformed homopolymers composed of patchy NPs of different sizes or surface chemical groups,block copolymers are also *** study provides insight into the process of self-assembly of two-patch NPs by precisely designing the components to generate colloidal analogues of linear macromolecular chains.

关键词： colloidal polymers nanoparticles patchy self-assembly

Stakeholders’power in the networking structuration processes of the urban resilience concept in Habitat III agenda(2012-2016)

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Geography and Sustainability 2022年第1期3卷 46-57页

作者： Daniela Mariño céline Rozenblat Institute of Geography and Sustainability Faculty of GeosciencesUniversity of LausanneLausanne 1015Switzerland

The urban resilience concept was introduced in 2016 as a key concept in the Habitat III New Urban Agenda for the next 20 *** wonder how this urban resilience concept was elaborated and who influenced it the most?The preparatory events structured several stakeholders’*** relations between stakeholders allowed the flow of ideas in the consultation and production *** influential stakeholders strongly oriented definition of urban resilience concepts by taking power in the networking process of the consecutive *** paper analyzes the network of stakeholders/concepts,during the building process between 2012 and 2016(5,539 discourses from 290 stakeholders,in 357 events).The application of textual mining and machine learning topic modelling algorithm exposed the structure of the principal topics for building the concept of urban resilience,and presented how relations of main stakeholders with funders was crucial for the investment in policy ***,we underlined for the first time in an empirical way,different kinds of actors’power in the construction process that supported the Habitat III resilience *** demonstrated how far some official stakeholders,but also external and private ones,oriented the construction of ideologies to validate the knowledge that supported the related actions in laboratory cities.

关键词： Urban resilience cities Habitat III Urban agenda Networks of power Global

Does a shift in shade tolerance as suggested by seedling morphology explain differences in regeneration success of northern red oak in native and introduced ranges?

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Journal of Forestry Research 2022年第3期33卷 949-962页

作者： Peter Nosko Kerri moreau christian Kuehne Kelly c.Major Jürgen Bauhus Department of Biology and chemistry Nipissing UniversityNorth BayONP1B 8L7Canada chair of Silviculture Freiburg University79085FreiburgGermany Division of Forestry and Forest Resources Norwegian Institute of Bioeconomy ResearchP.O.Box 1151431ÅsNorway Tulloch Engineering 1942 Regent StUnit LSudburyONP3E 5V5Canada

Across North America, forests dominated by Quercus rubra L. (northern red oak), a moderately shade-tolerant tree species, are undergoing successional replacement by shade-tolerant competitors. Under closed canopies, Q. rubra seedlings are unable to compete with these shade-tolerant species and do not recruit to upper forest strata. In Europe, natural regeneration of introduced Q. rubra is often successful despite the absence of fire, which promotes regeneration in the native range. considering that understorey light availability is a major factor affecting recruitment of seedlings, we hypothesized that Q. rubra seedlings are more shade tolerant in the introduced range than in the native range. Morphological traits and biomass allocation patterns of seedlings indicative of shade tolerance were compared for Q. rubra and three co-occurring native species in two closed-canopy forests in the native range (Ontario, canada) and introduced range (Baden-Württemburg, Germany). In the native range, Q. rubra allocated a greater proportion of biomass to roots, while in the introduced range, growth and allocation patterns favored the development of leaves. Q. rubra seedlings had greater annual increases in height, diameter and biomass in the introduced range. Q. rubra seedlings in the introduced range were also younger;however, they had a mean area per leaf and a total leaf area per seedling that were five times greater than seedlings in the native range. Such differences in morphological traits and allocation patterns support the hypothesis that Q. rubra expresses greater shade tolerance in the introduced range, and that natural regeneration of Q. rubra is not as limited by shade as in the native range. The ability of Q. rubra seedlings to grow faster under closed canopies in Europe may explain the discrepancy in regeneration success of this species in native and introduced ranges. Future research should confirm findings of this study over a greater geographical range in native

关键词： Alien species cross-continental study Forest regeneration Introduced species Seedling morphology Plant functional traits Quercus rubra

Using miniaturized GPS archival tags to assess home range features of a small plunge-diving bird:the European Kingfisher(Alcedo atthis)

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Avian Research 2021年第3期12卷 354-363页

作者： Raphaël Musseau Melina Bastianelli clementine Bely céline Rousselle Olivier Dehorter BioSphère Environnement 52 quai de l’Estuaire17120 Mortagne-sur-GirondeFrance centre de Recherches sur la Biologie des Populations d’Oiseaux UMR 7204 CNRS MNHN SU‒CESCO:Centre d’Ecologie et des Sciences de la ConservationMuséum National d’Histoire Naturelle43 rue Buffoncase postale 13575005 ParisFrance

Background:The European Kingfisher(Alcedo atthis)is a small plunge-diving bird,today considered a species of conservation concern in Europe given its rapid population decline observed across the *** implemented a pilot study aimed at providing first data allowing to:(1)assess home range features of the European Kingfisher for populations with unevenly distributed feeding habitats;(2)define conservation implications for habitats exploited by such populations;and(3)evaluate possibilities for developing GPS tracking schemes dedicated to home range stud-ies for this species that could be possibly applied to other small plunge-diving ***:In 2018 and 2019,we equipped 16 breeding European Kingfishers sampled within the marshes of the Gironde Estuary(France),with miniaturized and waterproof GPS archival tags deployed with leg-loop harnesses(total equipment mass=1.4 g;average bird mass=40.18±1.12 g).Results:On average,we collected 35.31±6.66 locations usable for analyses,without a significant effect on bird body condition(n=13 tags retrieved).Data analyses highlighted rather limited home ranges exploited by birds(aver-age=2.50±0.55 ha),composed on average by 2.78±0.40 location *** results also underscore:(1)a rather important home range fragmentation index(0.36±0.08);and(2)the use by birds of different types of small wetlands(wet ditches,small ponds or small waterholes),often exploited in addition to habitats encompassing nest ***:Our study reveals interesting GPS tracking possibilities for small plunge-diving birds such as the European *** this species,today classified as vulnerable in Europe,our results underline the importance of developing conservation and ecological restoration policies for wetland networks that would integrate small wet-lands particularly sensitive to global change.

关键词： GPS tracking Habitat connectivity Small wetlands Waterbirds Wetland ecological networks