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chinese Annals of Mathematics,Series B 2017年第2期38卷 513-538页

作者： Alexander LORZ Benoit PERTHAME cécile TAING Sorbonne Universits UPMC Univ Paris 06InriaLaboratoire Jacques-Louis Lions UM R CNRS 7598F75005 ParisFrance

This paper deals with a non-local parabolic equation of Lotka-Volterra type that describes the evolution of phenotypically structured populations. Nonlinearities appear in these systems to model interactions and competition phenomena leading to selection. In this paper, the equation on the structured population is coupled with a differential equation on the nutrient concentration that changes as the total population *** methods aimed at showing the convergence of the solutions to a moving Dirac mass are reviewed. Using either weak or strong regularity assumptions, the authors study the concentration of the solution. To this end, BV estimates in time on appropriate quantities are stated, and a constrained Hamilton-Jacobi equation to identify where the solutions concentrates as Dirac masses is derived.

关键词： Adaptive evolution, Asymptotic behaviour, chemostat, Dirac concentrations,Hamilton-Jacobi equations, Lotka-Volterra equations, Viscosity solutions

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Impact of introducing a herb pasture area into a New Zealand sheep and beef hill country farm system: a modeling analysis

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Frontiers of Agricultural Science and Engineering 2018年第1期5卷 87-97页

作者： cécile DURANTON cory MATTHEW Institute of Agriculture and Environment Massey University

New Zealand is well known for export of meat and dairy products from low cost pastoral systems. These farm systems are continually evolving for increased efficiency, in part through the use of metabolic energy modeling tools by farmers and farm consultants to explore alternative farm system configurations and identify new efficiencies. One recent innovation is the introduction of a herb pasture area, such as plantain. We used metabolic energy modeling to quantify seasonal feed flows in two successive years in a New Zealand hill country farm system, and to analyze the impact of the introduction of an area of plantain. Models employed were a self-built Microsoft Excel spreadsheet and a commercial New Zealand farm systems modeling package, *** production, animal performance and financial results for a base farm scenario created from the average of survey data for hill farms in the southern North Island, and the same farm with 10% and 20% of the area in plantain for the years 2010–2011 and 2011–2012 were modeled. The self-built model performed similarly to the commercial model. The system configuration of the base farm stockpiles surplus autumn feed for release to animals in winter and also incorporates flexibility that confers resilience to interannual weather variation through varying dates animals are purchased or sold. The introduction of an area of plantain was predicted to increase herbage production, animal performance and financial *** predicted benefit was higher for the year 2010–2011 where a drought occurred in summer than for the following year with higher summer rainfall. This demonstrates the profitability of introducing a plantain area to New Zealand hill farm systems, and suggests plantain will assist to mitigate adverse effects of warmer and drier summer conditions associated with current climate change trends.

关键词： farm system configuration herb pasture metabolic energy budgeting plantain sheep and beef farming

Lights at night:does photobiomodulation improve sleep?

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Neural Regeneration Research 2023年第3期18卷 474-477页

作者： Audrey Valverde catherine Hamilton cécile Moro Malvina Billeres Pierre Magistretti John Mitrofanis UniversitéGrenoble Alpes FDD and CEA-LETIClinatecGrenobleFrance WellRed Inc LauncestonTasmaniaAustralia King Abdullah University of Science and Technology Thuwal Saudi Arabia Institute of Ophthalmology University College LondonLondonUK

Sleep is a critical part of our daily *** impacts every organ and system of our body,from the brain to the heart and from cellular metabolism to immune function.A consistent daily schedule of quality of sleep makes a world of difference to our health and *** its importance,so many individuals have trouble sleeping *** quality sleep has such a detrimental impact on many aspects of our lives;it affects our thinking,learning,memory,and ***,and most poignantly,poor quality sleep over time increases the risk of developing a serious medical condition,including neurodegenerative *** this review,we focus on a potentially new non-pharmacological treatment that improves the quality of *** treatment,called photobiomodulation,involves the application of very specific wavelengths of light to body *** animal models,these wavelengths,when applied at night,have been reported to stimulate the removal of fluid and toxic waste-products from the brain;that is,they improve the brain’s inbuilt house-keeping *** suggest that transcranial nocturnal photobiomodulation,by improving brain function at night,will help improve the health and well-being of many individuals,by enhancing the quality of their sleep.

关键词： aquaporin 4 glymphhatic infrared non-pharmacological red sleep cap transcranial wakefulness

Expérience des parents faceàl’accompagnement pédiatrique en HAD:étude exploratoire qualitative Parents’Experience of Pediatric Home care:A Qualitative Exploratory Study

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Psycho-Oncologie 2024年第2期18卷 137-146页

作者： Laure Salomé Jérémy Martin camille Baussant-crenn cécile Flahault Institut de psychologie UniversitéParis CitéBouologne-Billancourt92774France Fondation Oeuvre de la croix Saint-Simon Service d’hospitalisationàdomicileParis75019France Laboratoire de Psychopathologie et Processus de SantéUR4057 UniversitéParis CitéBoulogne-Billancourt92774France

Aim:To investigate parents’experience of home care for children in oncology in order to identify the benefits,expectations,and possible difficulties *** and methods:A qualitative method was adopted,with non-directive interviews conducted with nine participants,then analyzed using thematic content ***:The main recurring themes in the discourse include:(1)relief,(2)positive representation of home,(3)positive representation of home care,and(4)negative representation of home *** these parents,home care appears to be positive overall,even though the introduction of home care is often reported as a source of stress for ***:These results must be interpreted with caution,but they do support previous research and highlight certain recommendations for further improving this experience,particularly for parents,but also for the sick child and the family.

关键词： Home care parents oncology pediatric children

Intraspecific maternal competition in insect parasitoids induces summer diapause in insect parasitoids

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Insect Science 2018年第6期25卷 1080-1088页

作者： Kévin Tougeron George Hraoui cécile Le Lann Joan van Baaren Jacques Brodeur UMR-cNRS 6553Ecobio Universitéde Rennes 1RennesFrance Université Bretagne Loire Cité InternationaleRennesFrance Département de Sciences Biologiques Institut de Recherche en Biologie VegétaleUniversitéde MontréalMontréalCanada

Organisms often live in unpredictable environments and have to adopt life history strategies that optimize their fitness under these *** to bet-hedging theory,individuals can reduce variation in fitness outcomes by investing in different strategies at the same *** arthropods,facultative summer diapause enables survival during dry and hot periods of the year,and can be triggered by a decrease in resource abundance. However,the effect of resource depletion on diapause induction has never been disentangled from the effect of the perception of the presence of *** two solitary parasitoid species of cereal aphids as a model system,Aphidius avenae (Haliday)and Aphidius rhopalosiphi (De Stefani-Perez)(Hymenoptera:Braconidae),we tested whether (i)low absolute host density and/or (ii)high levels of parasitoid females'competition lead to maternal-induced summer diapause in parasitoid *** summer-like climatic conditions,emerging parasitoid females were (i)reared alone and exposed to different host densities (from 5 to 130 aphids),or (ii)reared together with competing females (from 2 to 20 females)and then exposed individually to 50 *** both parasitoid species, low aphid densities did not induce summer ***,the incidence of summer diapause increased up to a maximum of 11% with increasing levels of competition expe rienced by female *** than 60% of the females produced both diapausing and nondiapausing offspring after being kept at the two highest competition densities. Such a "spreading-the-risk"strategy has likely evolved to optimize parasitoid fitness by preventing the following generation from exposure to low populations of suitable hosts and high mortality from *** results provide the first experimental evidence of direct maternal competition-induced diapause in insects,and may change the way we apprehend the evolution of arthropod seasonal ecology,by considering intraspecific c

关键词： aestivation bet-hedging host density intraspecific competition superparasitism

Process conditions for preparing well-defined nano- and microparticles as delivery systems of alkyl gallates

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Particuology 2019年第3期17卷 105-116页

作者： Asma chebil Denis Funfschilling Jean-Luc Six cécile Nouvel Alain Durand Michèle Léonard Universite de Lorraine CNRS LCPM F-54000 Nancy France Universite de Lorraine CNRS LRGP F-54000 Nancy France Universite de Strasbourg CNRS ICube F-67000 Strasbourg France

Dextran-covered poly(D,L-lactide) (PLA) nano-and microparticles were prepared using an emulsion/solvent evaporation (or diffusion) process for the encapsulation of alkyl gallates (AGs).In the first step,a solution of PLA and AG in ethyl acetate was emulsified to give an aqueous phase containing a hydrophobically modified dextran,which acted as a *** second step involved solvent evaporation or *** emulsification conditions were varied,which allowed for the preparation of nanoand microparticle suspensions covering a wide range of surface-average particle diameters from 0.1 μm (sonication) to 500 μm (stirring with a magnetic bar),with narrow and reproducible size *** microfluidic emulsification in a flow-focusing system led to well-defined microparticles,in the 10-50 μm *** loaded with octyl gallate (OG) and nonyl gallate (NG) were obtained using the three processes,and we showed that the encapsulation efficiency of OG and NG varied significantly depending on the emulsification *** effect of particle size on the mechanism of in vitro release of encapsulated AGs was *** kinetics of release were controlled either by Fickian diffusion within the solid core or swelling and hydrolytic degradation of the PLA matrix,depending on the pH of the external medium.

关键词： Emulsion/solvent evaporation Dextran Poly(D.L-lactide) Encapsulation Release Alkyl gallate

Perception of unrelated microbe-associated molecular patterns triggers conserved yet variable physiological and transcriptional changes in Brassica rapa ***

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Horticulture Research 2020年第1期7卷 331-342页

作者： Wanhui Kim Maxim Prokchorchik Yonghua Tian Seulgi Kim Hyelim Jeon cécile Segonzac Department of Plant Science Plant Genomics and Breeding Institute and Research Institute of Agriculture and Life SciencesSeoul National UniversitySeoul 08826Republic of Korea Plant Immunity Research center Seoul National UniversitySeoul 08826Republic of Korea Life Sciences Department Pohang University of Science and TechnologyPohang 37673Republic of Korea Department of Agriculture Forestry and BioresourcesSeoul National UniversitySeoul 08826Republic of Korea

Pattern-triggered immunity(PTI)includes the different transcriptional and physiological responses that enable plants to ward off microbial ***-localized pattern-recognition receptors(PRRs)recognize conserved microbeassociated molecular patterns(MAMPs)and initiate a branched signaling cascade that culminate in an effective restriction of pathogen *** the model species Arabidopsis thaliana,early PTI events triggered by different PRRs are broadly conserved although their nature or intensity is dependent on the origin and features of the detected *** order to provide a functional basis for disease resistance in leafy vegetable crops,we surveyed the conservation of PTI events in Brassica rapa *** identified the PRR homologs present in *** genome and found that only one of the two copies of the bacterial Elongation factor-Tu receptor(EFR)might *** also characterized the extent and unexpected specificity of the transcriptional changes occurring when *** seedlings are treated with two unrelated MAMPs,the bacterial flagellin flg22 peptide and the fungal cell wall component ***,using a MAMP-induced protection assay,we could show that bacterial and fungal MAMPs elicit a robust immunity in ***,despite significant differences in the kinetic and amplitude of the early signaling *** data support the relevance of PTI for crop protection and highlight specific functional target for disease resistance breeding in Brassica crops.

关键词： breeding crops immunity

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

ce^(3+):Lu_(3)Al_(5)O_(12)–Al_(2)O_(3) optical nanoceramic scintillators elaborated via a low-temperature glass crystallization route

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Journal of Advanced ceramics 2023年第2期12卷 268-278页

作者： Jie FU Shaowei FENG Yongchang GUO Ying ZHANG cécile GENEVOIS Emmanuel VERON Mathieu ALLIX Jianqiang LI School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Multiphase complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China cNRS CEMHTI UPR 3079Universitéd’OrléansOrléans 45071France University of chinese Academy of Sciences Beijing 100049China

Transparent ce:lutetium aluminum garnet(ce:Lu_(3)A_(l5)O_(12),ce:LuAG)ceramics have been regarded as potential scintillator materials due to their relatively high density and atomic number(Zeff).However,the current ce:LuAG ceramics exhibit a light yield much lower than the expected theoretical value due to the inevitable presence of LuAl antisite defects at high sintering *** work demonstrates a low-temperature(1100℃)synthetic strategy for elaborating transparent LuAG–Al_(2)O_(3) nanoceramics through the crystallization of 72 mol%Al_(2)O_(3)–28 mol%Lu_(2)O_(3)(ALu28)bulk *** biphasic nanostructure composed of LuAG and Al_(2)O_(3) nanocrystals makes up the whole ceramic *** of Al_(2)O_(3) is distributed among LuAG grains,and the rest is present inside the LuAG *** dense biphasic LuAG–Al_(2)O_(3) nanoceramics are highly transparent from the visible region to mid-infrared(MIR)region,and particularly the transmittance reaches 82%at 780 ***,LuAl antisite defect-related centers are completely undetectable in X-ray excited luminescence(XEL)spectra of ce:LuAG–Al_(2)O_(3) nanoceramics with 0.3–1.0 at%*** light yield of 0.3 at%ce:LuAG–Al_(2)O_(3) nanoceramics is estimated to be 20,000 ph/MeV with short 1μs shaping time,which is far superior to that of commercial Bi_(4)Ge_(3)O_(12)(BGO)single *** results show that a low-temperature glass crystallization route provides an alternative approach for eliminating the antisite defects in LuAG-based ceramics,and is promising to produce garnet-based ceramic materials with excellent properties,thereby meeting the demands of advanced scintillation applications.

关键词： glass crystallization garnet antisite defects Lu_(3)Al_(5)O_(12)-Al_(2)O_(3)(LuAG-Al_(2)O_(3))transparent ceramics nanoceramics scintillation