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Cold adaptation does not alter ATP homeostasis during cold exposure in Drosophila melanogaster

Integrative Zoology 2018年第4期13卷 471-481页

作者： Caroline M.WILLIAMS James R.ROCCA Arthur S.EDISON David B.ALLISON Theodore J.MORGAN Daniel A.hahn Department of Integrative Biology University of CaliforniaBerkeleyCaliforniaUSA Departments of Entomology and Nematology University of FloridaGainesvilleFloridaUSA Biochemistry University of FloridaGainesvilleFloridaUSA Advanced Magnetic Resonance Imaging and Spectroscopy Facility McKnight Brain InstituteUniversity of FloridaGainesvilleFloridaUSA Departments of Genetics and Biochemistry Complex Carbohydrate Research CenterUniversity of GeorgiaAthensGeorgiaUSA Department of Epidemiology and Biostatistics School of Public HealthIndiana University BloomingtonBloomingtonIndianaUSA Division of Biology Kansas State UniversityManhattanKansasUSA

In insects and other ectotherms,cold temperatures cause a coma resulting from loss of neuromuscular function,during which ionic and metabolic homeostasis are progressively *** adaptation improves homeostasis during cold exposure,but the ultimate targets of selection are still an open *** acclimation and adaptation remodels mitochondrial metabolism in insects,suggesting that aerobic energy production during cold exposure could be a target of ***,we test the hypothesis that cold adaptation improves the ability to maintain rates of aerobic energy production during cold exposure by using^(31)P NMR on live *** lines of Drosophila melanogaster artificially selected for fast and slow recovery from a cold coma,we show that cold exposure does not lower ATP levels and that cold adaptation does not alter aerobic ATP production during cold ***-hardy and cold-susceptible lines both experienced a brief transition to anaerobic metabolism during cooling,but this was rapidly reversed during cold exposure,suggesting that oxidative phosphorylation was sufficient to meet energy demands below the critical thermal minimum,even in cold-susceptible *** thus reject the hypothesis that performance under mild low temperatures is set by aerobic ATP supply limitations in ***,excluding oxygen and capacity limitation as a weak link in energy *** work suggests that the modulations to mitochondrial metabolism resulting from cold acclimation or adaptation may arise from selection on a biosynthetic product(s)of those pathways rather than selection on ATP supply during cold exposure.

关键词： chill coma energetics insect oxygen limitation thermal tolerance

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Cautious interpretation of coulombic efficiency(CE) in lithium metal batteries

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Journal of Energy Chemistry 2021年第5期30卷 34-36页

作者： Fu Sun dong Zhou Xiaogang Wang Ingo Manke Libao Chen Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101ShandongChina Ningbo Institute of Materials Technology&Engineering Chinese Academy of SciencesNingbo 315201ZhejiangChina Institute of Applied Materials Helmholtz-Zentrum Berlin fiir Materialien und EnergieHahn-Meitner-Platz 114109 BerlinCermany State Key Laboratory for Powder Metallurgy Central South UniversityChangsha 410083HunanChina

The soaring demand for electrical energy storage technologies stimulated by advanced portable devices, prospering electric vehicles, and large-scale grid storage applications have triggered explosive research on Li metal battery (LMB), which has been widely acknowledged as the most promising energy storage technology of the future that can break the energy-density bottleneck of the state-of-art lithium-ion battery (LIB) technology [1,2].

关键词： Coulombic efficiency Lithium metal anode Lithium metal battery Lithium ion battery

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Expression of protein S100A4 is a predictor of recurrence in colorectal cancer

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World Journal of Gastroenterology 2010年第31期16卷 3897-3904页

作者： Jung Myun Kwak Hyun Joo Lee Seon hahn Kim Han Kyeom Kim Young Jae Mok Young Tae Park Jong Sang Choi Hong Young Moon Department of Surgery Korea University Anam Hospital Department of Pathology Korea University Guro Hospital Department of Surgery Korea University Guro Hospital Department of Gastroenterology Korea Uni-versity Guro Hospital

AIM: To investigate the prognostic significance of S100A4 expression in colorectal cancer and its correlation with expression of E-cadherin and p53. METHODS: A cohort of archival formalin-fixed paraff inembedded specimens was selected from 127 patients with colorectal cancer who underwent surgical resection between April 2000 and March 2004 at the Department of Surgery, Korea University Guro Hospital. The expression of protein S100A4 was evaluated according to the proportion of positively stained cancer cells. In each case, three core biopsies with a diameter of 2 mm were punched out and positioned in a recipient paraff in array block. Four-μm sections of these tissue array blocks were used for immunohistochemical analysis of protein S100A4, E-cadherin, and p53. Clinicopathological data were based on the original histopathologic reports and clinical records of patients. RESULTS: In normal colorectal mucosa, protein S100A4 immunoreactivity was clearly absent in both cytoplasm and nucleus. However, positive immunoreactivity of protein S100A4 was detected in 45 (35.4%) of the tumor cases. There was no significant association between positive immunoreactivity of protein S100A4 and clinicopathological parameters such as tumor differentiation or TNM stage, and also no correlation between the reactivity and E-cadherin or p53 expression. However, positive immunoreactivity of protein S100A4 was found to be associated with tumor recurrence (P = 0.004), and was also associated with significantly worse overall survival in the Kaplan-Meyer survival analysis (P = 0.044). After adjustment for tumor differentiation, tumor depth and nodal status, however, it failed to achieve statistical significance (P = 0.067). CONCLUSION: The expression of protein S100A4 is associated with tumor recurrence and poor overall survival in patients with colorectal cancer.

关键词： S100A4 E-cadherin p53 Prognostic factor Colorectal cancer

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无障碍旅游-提升竞争地位的潜力与机遇

无障碍旅游-提升竞争地位的潜力与机遇

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作者： hahn Sebastian 海南大学

学位级别：硕士

为着重分析和了解海口市的无障碍环境状况,首先,我们展示了无障碍设施对当地经济的潜在影响（通用设计环境的成本和收益）,行动不便人士的旅游市场规模以及为什么我们需要国家监管。本研究基于通用设计的通用要求以及可访问性的要求,选... 详细信息

为着重分析和了解海口市的无障碍环境状况,首先,我们展示了无障碍设施对当地经济的潜在影响（通用设计环境的成本和收益）,行动不便人士的旅游市场规模以及为什么我们需要国家监管。本研究基于通用设计的通用要求以及可访问性的要求,选择了易于测量或非常明显的要求（例如:有步骤或没有步骤）。然后,根据这些要求,我们制定了审核清单,并据此检查了海口市25家酒店的无障碍环境状况。并根据审核列表检查机场,火车站和公共汽车站以及旧街上的在线信息。研究结果表明,海口市缺乏无障碍环境,当前的无障碍通道主要是提高市容环境,没有真正作用无障碍通道需求的人,不可能有任何旅行链。

关键词：无障碍旅游行动不便的人残疾人通用设计

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The Bioavailability of Vitamin E in Fortified Processed Foods

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Food and Nutrition Sciences 2012年第3期3卷 329-336页

作者： Inga Schneider Ute Bindrich Andreas hahn German Institute of Food Technologies Quakenbrück Germany. Institute of Food Science and Human Nutrition Leibniz University of Hannover Hannover Germany Institute of Food Science and Human Nutrition Leibniz University of Hannover Hannover Germany

Objectives: Vitamin E is an important human lipophilic antioxidant and is required for many metabolic functions. A high vitamin E intake appears to favorably impact a variety of disease processes. The vitamin E intake, excluding sup-plemental intake, of the vast majority of adults is below the current recommended level. By consuming vitamin E-enriched food, it is possible to take in adequate amounts of vitamin E. Vitamin E intake from enriched foods might prevent certain diseases without the need to ingest specific vitamin E supplements. The vitamin E that is present in enriched foods has to exhibit maximal bioavailability to ensure a sufficient intake of vitamin E from one portion of fortified food. The aim of the present study was to develop an enriched food that has highly bioavailable vitamin E. Furthermore, we wanted to examine whether vitamin E bioavailability can be affected by the technological properties of fortified food. Methods: Volunteers were given test foods (cream cheese and mayonnaise) that had been fortified with 60 mg of RRR-α-tocopherol. The test foods were technologically modified and the bioavailability of RRR-α-tocopherol was determined via a short-term kinetic measurement, which was 24 h long, and a long-term kinetic measurement, which was 28 d long. The test foods were characterized with respect to matrix properties. Results: In comparison to the mayonnaise group the serum α-tocopherol area under the curve (AUC) was significantly higher in the cream cheese group, as shown in the short-term kinetic (p = 0.010) and long-term kinetic (p = 0.017) studies. Conclusions: In conclusion, RRR-α-tocopherol was more bioavailable in cream cheese than in mayonnaise in both short-term and long-term periods. Hence, food matrices affect bioavailability of RRR-α-tocopherol. Fortified foods with proven high α-tocopherol bioavailabilities could be merchandised as functional foods with diseases prevention properties.

关键词： Vitamin E Bioavailability Emulsion Cream Cheese Mayonnaise

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Solar Driven Wind Speed Monitoring System Using Wireless or Wired Sensors

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Energy and Power Engineering 2014年第9期6卷 213-221页

作者： Federico hahn Mauricio Pablo José Reyes Department of Irrigation Universidad Autonoma Chapingo Texcoco México

Instrumented towers are being constructed to characterize vertical wind profiles in order to improve the understanding and characterization of a desired environment up to 100 m. The site being measured is at a height of 2500 m over sea level, in one side of Sierra Madre Oriental, which crosses Mexico from North to South. As the site has no energy, it was powered by a photovoltaic system. Power consumption of two sets of sensors fixed at the tower was evaluated. The first sensor set consisted of a pulsed anemometer and a RH sensor having a 0 - 10 V output;these sensors used cables for transmitting the output signals. Three cup anemometers fixed at 25, 35 and 45 m high measured wind speed. Wireless sensors in the second set, requires of a power consumption and battery life study. Solar cells energized the sensors, becoming the installation and operation easier. The datalogger that acquired the RH and T measurements encountered an 11% voltage loss throughout the cable;cup anemometer measurements did not show variations due to its pulsed signals. Wireless sensors drew less energy from the PV system, resulting in battery overcharge. A dump regulator turned-on a 200 W lamp during the night when the battery voltage reached 14 V;the lamp was turned-off when the battery voltage felt beneath 11.5 V. Considering the high wind available, wireless sensors batteries were charged by small wind turbines combined with 5 W solar panels.

关键词： Wind Tower Wireless Anemometers Battery Regulator

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Improved color feature arrangement for mean shift tracking

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Journal of Measurement Science and Instrumentation 2013年第1期4卷 38-42页

作者： Xiaowei An Youngjoon Han Hernsoo hahn Dept.of Electronic Engineering Soongsil UniversitySeoul 156-743Korea

In order to reduce redundant empty bin capacity in the probability representation,we present a new color feature arrangement mechanism for mean shift tracking *** the proposed mechanism,the important optimal color,or we call it optimal color vector,is clustered by closing Euclidean distance which happens inside the original RGB color 3-D spatial *** obtaining clustering colors from the reference image RGB spatial domain,novel clustering groups substitute for original color *** the new color substitution distribution is as similar as the original *** then target region in the candidate frame is mapped by the constructed optimal clustering colors and the cluster *** the final,mean shift algorithm gives a performance in the new optimal color *** under the same circumstance between the proposed algorithm and conventional mean shift algorithm shows that the former has a certain advantage in computation cost.

关键词： color feature arrangement optimal color vector cluster redundant bin

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从讲座制到学系制——兼论德国大学与美国大学的相互影响

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江苏高教 2011年第2期 150-152,155页

作者：孔捷迟芳 Matthias hahn 南京理工大学人事处南京210094 凯泽斯劳滕大学生物系德国凯泽斯劳滕d67663

讲座制在德国大学的形成,确立了现代大学的科学研究职能,德国大学因此成为当时世界上最好的大学,并对世界高等教育产生重要影响。美国大学对德国大学讲座制进行继承和发扬,形成了如今的学系制;自20世纪30年代,美国逐渐代替德国成为新的... 详细信息

讲座制在德国大学的形成,确立了现代大学的科学研究职能,德国大学因此成为当时世界上最好的大学,并对世界高等教育产生重要影响。美国大学对德国大学讲座制进行继承和发扬,形成了如今的学系制;自20世纪30年代,美国逐渐代替德国成为新的世界高等教育中心,至今对世界各国产生影响。始于20世纪60年代的德国高等教育体制改革,更是效法美国,试图重返世界高等教育领袖地位。借鉴和创新成为德、美两国大学相互影响的基本历史脉络。

关键词：讲座制学系制学术组织大学制度德国大学美国大学

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铂电极电解气浮的研究

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中国给水排水 1993年第6期9卷 4-9页

作者：张林生 H.hahn 江苏石油化工学院德国卡斯鲁尔大学

通过实验研究铂电极电解气浮法的基本特性和所产生微气泡的性质,分析评价电气浮法在水处理技术中的负荷率及能耗水平。

关键词：水处理铂电极电气浮法

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Formation of intermetallic phases in unrefined and refined AA6082 Al alloys investigated by using SEM-based ultramicrotomy tomography

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Journal of Materials Science & Technology 2022年第25期120卷 118-128页

作者： J.M.Yu T.Hashimoto H.T.Li N.Wanderka Z.Zhang C.Cai X.L.Zhong J.Qin Q.P.dong H.Nagaumi X.N.Wang Shagang School of Iron and Steel and High-Performance Metal Structural Materials Research Institute Soochow UniversitySuzhou 215137China School of Materials The University of ManchesterSackville StreetManchester M139PLUK Chinalco Materials Application Research Institute Co.Ltd. Beijing 102200China Helmholtz-Zentrum Berlin Für Materialien und Energie Hahn-Meitner-Platz 1Berlin 14109Germany Key Laboratory of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China

The spatial arrangement,distribution and morphology of Fe-bearing intermetallics in AA6082 alloys depends on the manufacturing process of the alloy and thus influences the macroscopic ***,the microstructure of a near industrial scale casting AA6082 Al alloy fabricated by:(a)direct chill casting,(b)Al-5 Ti-1 B grain refiner addition and(c)intensive melt shearing has been investigated by threedimensional visualization using SEM-based serial ultra microtomy *** formation sequence of phases in AA6082 alloys is generally categorized into four stages:formation ofα-Al grains,Fe-bearing intermetallics,Mg_(2)Si phase,and eutectic *** of three-dimensional visualization of the microstructure indicated that TiBparticles not only could nucleate Fe-bearingβ-intermetallics,but also could provide substrate for the formation of Fe-bearingα-intermetallics and Mg_(2)Si.A further deep analysis reveals that the essential condition for the formation of secondary phases such as Fe-bearing intermetallics and Mg_(2)Si phase is the build-up of a supersaturated solute front at theα-Al solid-liquid interface irrespective of the specific nucleation *** addition,the results indicate that grain refinement processing causes the severe interconnectivity of Fe-bearingα-***,the intensive melt shearing is a better manufacturing process because the intermetallics are more evenly distributed and refined than with the addition of the grain refiner,thereby improving the properties of the alloy.

关键词： Al-Si-Mg alloy Grain refinement Al-Fe-Si intermetallic phase Tomography Ultramicrotomy Mg2Si

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