检索结果-南通市图书馆

Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients

World Journal of Gastroenterology 2022年第9期28卷 933-947页

作者： Yonghoon Choi Nayoung Kim Ki Wook Kim Hyeong Ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong Ho Lee Hyeon Jeong Oh Hye Seung Lee Young Suk Park Sang-hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-Ho Kim ji-Won Kim jin Won Kim Keun-Wook Lee Won Chang ji hoonPark Yoon jin Lee Kyoung Ho Lee Young hoon Kim Department ofInternal Medicine Seoul National University Bundang HospitalSeongnam 13620South Korea Nayoung Department of Internal Medicine Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University College of MedicineSeoul 03080South Korea Department of Surgery Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Surgery Seoul National University College of MedicineSeoul 03080South Korea Department of Radiology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Radiology Seoul National University College of MedicineSeoul 03080South Korea

BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for *** A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang Hospital between 2003 and 2017 were *** clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were *** Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, *** average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P < 0.001).Cancer of the gastric body(P < 0.001) and diffuse-type histology(P < 0.001) were more common in females than in *** trend was more prominent in females younger than 60 years of age, with a significantly higher proportion of diffuse-type cancer than in the male *** of sex, diffuse-type GC was more common in younger patients, and the proportion of intestinal-type GC increased with *** overall survival rate was significantly higher in females(P < 0.001).However, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type *** terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in *** Sex-based differences in GC were

关键词： Gastric cancer Histology Prognosis Sex difference Survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current practice of gastric cancer treatment

引用

Chinese Medical Journal 2014年第3期127卷 547-553页

作者： Yoon Young Choi ji Yeong An Hyung-Il Kim Jae-Ho Cheong Woo jin Hyung Sung hoon Noh Department of Surgery Yonsei University Health System Yonsei University College of Medicine Seoul Republic of Korea

Objective The aim of this review was to overview the current practice of gastric cancer treatment including surgery and other adjuvant *** sources The review was based on data obtained from the published articles and main guidelines in the East and *** selection Articles with high level of evidence or current best evidence in each issue were selected to be *** Although varied adjuvant modalities have been proved to be benefit for treating gastric cancer,surgery is still the most important treatment strategy against gastric *** adapting to new technology is important but it should be balanced with an effort to establish sound scientific rationale that adheres to oncologic *** Future treatment of gastric cancer will be focused on tailored,personalized *** achieving it,collaboration across disciplines is *** the philosophy of caring for the patients with gastric cancer should be rooted in the realization of true patient benefit regardless of who is providing the *** these philosophies,we can shift the scientific and technological advances toward triumph over gastric cancer.

关键词： gastric cancer treatment oncology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reevaluation of the expanded indications in undifferentiated early gastric cancer for endoscopic submucosal dissection

引用

World Journal of Gastroenterology 2022年第15期28卷 1548-1562页

作者： jiyoung Yoon Seung-Yeon Yoo Young Soo Park Kee Don Choi Beom Su Kim Moon-Won Yoo In Seob Lee Jeong Hwan Yook Ga Hee Kim Hee Kyong Na ji Yong Ahn Jeong hoon Lee Kee Wook Jung Do hoon Kim Ho June Song Gin Hyug Lee Hwoon-Yong Jung Department of Gastroenterology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Pathology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Surgery Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Although the criteria for the indication of endoscopic submucosal dissection(ESD)for undifferentiated early gastric cancer(UD-EGC)have been recently proposed,accumulating reports on the non-negligible rate of lymph node metastasis(LNM)after indicated ESD raise questions on the reliability of the current *** To investigate the prevalence and risk factors of LNM in UD-EGC cases meeting the expanded indication for *** We retrospectively reviewed 4780 UD-EGC cases that underwent surgical resection between January 2008 and February 2019 at Asan Medical Center,a tertiary university hospital in *** identify the risk factors of LNM of UDEGC meeting the expanded criteria for ESD,we performed a case-control study by matching the cases with LNM to those without at a ratio of 1:*** reviewed the clinical,endoscopic,and histologic features of the cases to identify features with a significant difference according to the presence of *** and multivariate logistic regression analyses were performed to estimate the odds ratios(ORs).RESULTS Of the 4780 UD-EGC cases,1240(25.9%)were identified to meet the expanded indication for *** the 1240 cases,14(1.1%)cases had *** the various clinical,endoscopic,and histopathological features that were evaluated,mixed histology(tumors consisting of 10%-90%of signet ring cells)had a marginally significant association(P=0.059)with the risk of ***,diffuse blurring of the muscularis mucosae(MM)underneath the tumorous epithelium,a previously unrecognized histologic feature,had a significant association with the absence of LNM(P=0.028).Multivariate logistic regression analysis showed that the blurring of MM was the only explanatory variable significantly associated with a reduced risk of LNM(OR:0.12,95%CI:0.02-0.95;P=0.045).CONCLUSION The risk of LNM is higher than expected when using the current expanded indication for *** evaluation could provide useful clues for reducing the

关键词： Gastric cancer Undifferentiated carcinoma Endoscopic submucosal dissection Lymph node metastasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Timing of upper gastrointestinal endoscopy does not influence short-term outcomes in patients with acute variceal bleeding

引用

World Journal of Gastroenterology 2018年第44期24卷 5025-5033页

作者： Jeong-Ju Yoo Young Chang Eun Ju Cho ji Eun Moon Sang Gyune Kim Young Seok Kim Yun Bin Lee Jeong-hoon Lee Su Jong Yu Yoon Jun Kim Jung-Hwan Yoon Department of Gastroenterology and Hepatology Soonchunhyang University school of Medicine Bucheon 14584 South Korea Department of Internal Medicine and Liver Research Institute Seoul National University College of Medicine Seoul 03080 South Korea Department of Biostatistics Clinical Trial Center Soonchunhyang University Bucheon Hospital Bucheon 14584 South Korea

AIM To examine the association between the timing of endo-scopy and the short-term outcomes of acute variceal bleeding in cirrhotic *** This retrospective study included 274 consecutive patients admitted with acute esophageal variceal bleeding of two tertiary hospitals in Korea. We adjusted confounding factors using the Cox proportional hazards model and the inverse probability weighting （IPW） method. The primary outcome was the mortality of patients within 6 *** A total of 173 patients received urgent endoscopy （ i.e. , ≤ 12 h after admission）, and 101 patients received non-urgent endoscopy （〉 12 h after admission）. The 6-wk mortality rate was 22.5% in the urgent endoscopy group and 29.7% in the non-urgent endoscopy group, and there was no significant difference between the two groups before （P = 0.266） and after IPW （P = 0.639）. The length of hospital stay was statistically different between the urgent group and non-urgent group （P = 0.033）; however, there was no significant difference in the in-hospital mortality rate between the two groups （8.1%vs 7.9%, P = 0.960）. In multivariate analyses, timing of endoscopy was not associated with 6-wk mortality （hazard ratio, 1.297; 95% confdence interval, 0.806-2.089; P = 0.284）.CONCLUSION In cirrhotic patients with acute variceal bleeding, the timing of endoscopy may be independent of short-term mortality.

关键词： Cirrhosis Endoscopy Upper gastrointestinal bleeding Gastroesophageal varices Timing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

IL-1β activates p44/42 and p38 mitogen-activated protein kinases via different pathways in cat esophageal smooth muscle cells

引用

World Journal of Gastroenterology 2006年第5期12卷 716-722页

作者： Tai Sang Lee Hyun Ju Song ji hoon Jeong Young Sil Min Chang Yell Shin Uy Dong Sohn Department of Pharmacology College of PharmacyChung-Ang UniversitySeoul 156-756Republic of Korea Research Laboratory Dong-A Pharmaceuticals Co.LtdKyunggidoRepublic of Korea

AIM： To examine the pathway related to the IL-1β induced activation of mitogen-activated protein （MAP） kinases in cat esophageal smooth muscle cells. METHODS： Culture of the esophageal smooth muscle cells from cat was prepared. Specific inhibitors were treated before applying the IL-β3. Western blot analysis was performed to detect the expressions of COX, iNOS and MAP kinases. RESULTS： In the primary cultured cells, although IL-β3 failed to upregulate the COX and iNOS levels, the levels of the phosphorylated forms of 1344142 HAP kinase and p38 MAP kinase increased in both concentration- and time-dependent manner, of which the level of activation reached a maximum within 3 and 18 h, respectively. The pertussis toxin reduced the level of p44/42 MAP kinase phosphorylation. Tyrphostin 51 and genistein also inhibited this activation. Neomycin decreased the density of the p44/42 HAP kinase band to the basal level. Phosphokinase C （PKC） was found to play a mediating role in the IL-1β-induced p44/42 MAP kinase activity. In contrast, the activation of p38 MAP kinase was inhibited only by a pretreatment with forskolin, and was unaffected by the other compounds. CONCLUSION： Based on these results, IL-1β-induced p44/42 MAP kinase activation is mediated by the Gi protein, tyrosine kinase, phospholipase C （PLC） and PKC. The pathway for p38 MAP kinase phosphorylation is different from that of p44/42 MAP kinase, suggesting that it plays a different role in the cellular response to IL- 1β.

关键词： IL-1β MAP kinase Esophageal smoothmuscle cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Curvature range measurements of the arcuate fasciculus using diffusion tensor tractography

引用

Neural Regeneration Research 2013年第3期8卷 244-250页

作者： Dong hoon Lee Cheol Pyo Hong Yong Hyun Kwon Yoon Tae Hwang Joong Hwi Kim ji Won Park Department of Radiological Science College of Health ScienceYonsei University Department of Physical Therapy Yeungnam College of Science & Technology Department of Physical Therapy Gangneung Yeongdong College Department of Physical Therapy College of Medical ScienceCatholic University of DaeguGyeongsan-si

Because Broca＇s area and Wernicke＇s area in the brain are connected by the arcuate fasciculus, understanding the anatomical location and morphometry of the arcuate fasciculus can help in the treatment of patients with aphasia. We measured the horizontal and vertical curvature ranges of the arcuate fasciculus in both hemispheres in 12 healthy subjects using diffusion tensor tractography. In the right hemisphere, the direct curvature range and indirect curvature range values of the arcuate fasciculus horizontal part were 121.13 ± 5.89 and 25.99 ± 3.01 degrees, respectively, and in the left hemisphere, the values were 121.83 ± 5.33 and 27.40 ± 2.96 degrees, respectively. In the right hemisphere, the direct curvature range and indirect curvature range values of the arcuate fasciculus vertical part were 43.97 ± 7.98 and 30.15 ± 3.82 degrees, respectively, and in the left hemisphere, the values were 39.39 ± 4.42 and 24.08 ± 4.34 degrees, respectively. We believe that the measured curvature ranges are important data for localization and quantitative assessment of specific neuronal pathways in patients presenting with arcuate fasciculus abnormalities.

关键词： neural regeneration neuroimaging clinical practice diffusion tensor tractography diffusion tensor imaging arcuate fasciculus direct curvature range indirect curvature range anatomical location quantitative information aphasia Broca’s area Wernicke’s area arched fiber grant-supported paper photographs-containing paper neuroregeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry

引用

Journal of Geriatric Cardiology 2020年第11期17卷 680-693页

作者： Myunhee Lee Dae-Won Kim Mahn-Won Park Kyusup Lee Kiyuk Chang Wook Sung Chung Tae hoon Ahn Myung Ho Jeong Seung-Woon Rha Hyo-Soo Kim Hyeon Cheol Gwon In Whan Seong Kyung Kuk Hwang Shung Chull Chae Kwon-Bae Kim Young Jo Kim Kwang Soo Cha Seok Kyu Oh Jei Keon Chae ji-hoon Jung 无 KAMIR-NIH registry investigators Division of Cardiology Daejeon St.Mary’s hospitalCollege of MedicineThe Catholic University of KoreaSeoulSouth Korea Division of Cardiology Seoul St.Mary’s hospitalCollege of MedicineThe Catholic University of KoreaSeoulSouth Korea Gachon University Gil Medical CenterIncheonSouth Korea Chonnam National University Hospital GwangjuSouth Korea d Korea University Korea University Guro Hospital SeoulSouth Korea Seoul National University Hospital SeoulSouth Korea Sungkyunkwan Universtiy Samsung Medical CenterSeoulSouth Korea Chungnam National University Hospital DaejeonSouth Korea Chungbuk National University Hospital CheongjuSouth Korea Kyungpook National University Hospital DaeguSouth Korea Keimyung University Dongsan Medical Center DaeguSouth Korea Yeungnam University Hospital DaeguSouth Korea Pusan National University Hospital BusanSouth Korea Wonkwang University Hospital IksanSouth Korea Chonbuk National University Hospital JeonjuSouth Korea Institute of Toxicology DaejeonSouth Korea 不详

Background There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention(PCI). Furthermore, gender differences in clinical outcomes with acute myocardial infarction(AMI) following PCI in Asian population remain uncertain because of the under-representation of Asian in previous trials. Methods A total of 13,104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institute of Health(KAMIR-NIH) between November 2011 and December 2015 were classified into male(n = 8021, 75.9%) and female(n = 2547, 24.1%). We compared the demographic, clinical and angiographic characteristics, 30-days and 1-year major adverse cardiac and cerebrovascular events(MACCE) in women with those in men after AMI by using propensity score(PS) matching. Results Compared with men, women were older, had more comorbidities and more often presented with non-ST segment elevation myocardial infarction(NSTEMI) and reduced left ventricular systolic function. Over the median follow-up of 363 days, gender differences in both 30-days and 1-year MACCE as well as thrombolysis in myocardial infarction minor bleeding risk were not observed in the PS matched population(30-days MACCE: 5.3% vs. 4.7%, log-rank P = 0.494, HR = 1.126, 95% CI: 0.800-1.585;1-year MACCE: 9.3% vs. 9.0%, log-rank P = 0.803, HR = 1.032, 95% CI: 0.802-1.328;TIMI minor bleeding: 4.9% vs. 3.9%, log-rank P = 0.215, HR = 1.255, 95% CI: 0.869-1.814). Conclusions Among Korean AMI population undergoing contemporary PCI, women, as compared with men, had different clinical and angiographic characteristics but showed similar 30-days and 1-year clinical outcomes. The risk of bleeding after PCI was comparable between men and women during one-year follow up.

关键词： Acute myocardial infarction Asian population Gender difference Percutaneous coronary intervention

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inhibitory Effect of Yukmijihwangtang on Osteoclast Differentiaion

Inhibitory Effect of Yukmijihwangtang on Osteoclast Differen...

引用

第十四届全国中药和天然药物学术研讨会

作者： Jung Young Kim ji hoon Kim Yun Kyung Kim Wongwang University

＜正＞Nowadays,osteoporosis is a social problem around the *** is a bone disease that results from unusual balance between bone formation and bone *** osteoporosis does have no symptoms,osteoporosis caused by osteocla...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Residue patterns of buprofezin and teflubenzuron in treated peaches

引用

Journal of Agricultural Chemistry and Environment 2012年第1期1卷 10-14页

作者： ji-Young Yoon Jae-Hun Park Ye-hoon Han Kyu-Seung Lee Department of Bio-Environmental Chemistry Chungnam National University Daejeon South Korea Syngenta Korea Inc. Seoul South Korea

The biological half-life and final residue levels of buprofezin and teflubenzuron were examined in peaches over a 14-day cultivation period. The residue levels of buprofezin and teflubenzuron were analyzed by chromatographic method with recovery ranging from 84.0% to 96.6%. The biological half-lives of buprofezin andteflubenzuron were 4.88 and 11.49 days at the standard dose, and 4.40 and 10.86 days at a triple dose, respectively. The initial concentration of buprofezin exceeded the maximum residue limit (MRL) set in Korea, but the concentration decreased to below the MRL within 6 days after application. The initial and persisting concentrations of teflubenzuron were all below the prescribed MRL. The final residue levels of buprofezin and teflubenzuron were 0.17 and 0.10?mg·kg﹣1 following a standard single dose, and 0.20 and 0.23 mg·kg﹣1 following a triple dose, respectively. The final re-sidue levels of buprofezin and teflubenzuron were also compared with the good agricultural practices standards of the United States and Italy.

关键词： Biological Half-Life Buprofezin Peach Residue Teflubenzuron

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wax from Pyrolysis of Waste Plastics as a Potential Source of Phase Change Material for Thermal Energy Storage

引用

Transactions of Tianjin University 2023年第3期29卷 225-234页

作者： Pin jin Ong Zhi Xiong Jerry Heng Zhenxiang Xing Hnin Yu Yu Ko Pei Wang Hongfei Liu Rong ji Xizu Wang Beng hoon Tan Zibiao Li jian Wei Xu Xian Jun Loh Enyi Ye Qiang Zhu Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)2 Fusionopolis WayInnovis#08-03Singapore 138634Singapore Institute of Sustainability for Chemicals Energy and EnvironmentA*STAR(Agency for ScienceTechnology and Research)1 Pesek RoadJurong IslandSingapore 627833Singapore Department of Chemistry National University of Singapore3 Science Drive 3Singapore 117543Singapore Department of Material Science and Engineering National University of Singapore9 Engineering Drive 1#03-09 EASingapore 117575Singapore School of Chemistry Chemical Engineering and BiotechnologyNanyang Technological University21 Nanyang LinkSingapore 637371Singapore

Over the past half-century, plastic consumption has grown rapidly due to its versatility, low cost, and unrivaled functional properties. Among the diff erent implemented strategies for recycling waste plastics, pyrolysis is deemed the most economical option. Currently, the wax obtained from the pyrolysis of waste plastics is mainly used as a feedstock to manufacture chemicals and fuels or added to asphalt for pavement construction, with no other applications of wax being reported. Herein, the thermal pyrolysis of three common waste polyolefin plastics: high-density polyethylene(HDPE), low-density polyethylene(LDPE), and polypropylene(PP), was conducted at 450 ℃. The waste plastics-derived waxes were characterized and studied for a potential new application: phase change materials(PCMs) for thermal energy storage(TES). Gas chromatography–mass spectrometry analysis showed that paraffin makes up most of the composition of HDPE and LDPE waxes, whereas PP wax contains a mixture of naphthene, isoparaffin, olefin, and paraffin. Diff erential scanning calorimetry(DSC) analysis indicated that HDPE and LDPE waxes have a peak melting temperature of 33.8 ℃ and 40.3 ℃, with a relatively high latent heat of 103.2 J/g and 88.3 J/g, respectively, whereas the PP wax was found to have almost negligible latent heat. Fourier transform infrared spectroscopy and DSC results revealed good chemical and thermal stability of HDPE and LDPE waxes after 100 cycles of thermal cycling. Performance evaluation of the waxes was also conducted using a thermal storage pad to understand their thermoregulation characteristics for TES applications.

关键词： Pyrolysis Waste plastics Recycling Wax Phase change materials

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：