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Microstructure and mechanical properties of double-side friction stir welded 6082Al ultra-thick plates

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Journal of Materials science & Technology 2020年第6期41卷 105-116页

作者： C.Yang J.F.zhang G.N.Ma L.H.Wu X.M.zhang G.z.He P.Xue D.R.Ni B.L.Xiao K.s.Wang z.Y.Ma shenyang National Laboratory for Materials science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China school of Materials science and Engineering University of Science and Technology of ChinaShenyang 110016China CRRC Changchun Railway Vehicles Co. Ltd.Changchun 130062China school of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China

In the present work,80 mm thick 6082Al alloy plates were successfully double-side welded by friction stir welding(FsW).The relationship between the microstructures and mechanical properties was built for the double-side FsW butt joint with more attention paid to the local characteristic *** was shown that a phenomenon of microstructural inhomogeneity existed in the nugget zone(Nz)through the thickness *** grain size presented an obvious gradient distribution from the top to the bottom for each single-pass weld,and the microhardness values decreased from both surfaces to the middle of the *** lowest hardness zone(LHz)exhibited a"hyperbolical"-shaped distribution extending to the middle of the *** tensile properties were obtained in the three sliced specimens of the FsW joint,and the joint coefficient reached about 70%which achieved the same level as the conventional FsW Al alloy *** element modeling proved that the"hyperbolical"-shaped heat affected zone(HAz)was beneficial to resisting the strain concentration in the middle layer specimen which helped to increase the tensile *** on the analysis of the hardness contour map,tensile property and microstructural evolution of the joints,an Isothermal softening Layer(IsL)model was proposed and established,which may have a helpful guidance for the optimization on the FsW of ultra-thick Al alloy plates.

关键词： Ultra-thick aluminum alloy plates Double-side friction stir welding Finite element model Microstructural inhomogeneity Mechanical properties

UV Assisted Preliminary DNA Binding studies and single-crystal X-ray structure of 4-{(4-Nitrophenyl-sulfonamido)methyl}cyclohexanecarboxylic Acid

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Chinese Journal of structural Chemistry 2017年第5期36卷 745-750页

作者： MUHAMMAD Danish RABIA Ayub butt MUHAMMAD Nawaz Tahir MUHAMMAD Ashfaq sYEDA Tahira Hafeez Department of Chemistry University of GujratGujrat 50700Pakistan Department of Physics University of SargodhaSargodhaPakistan

A new sulfonamide, 4-{（4-nitrophenylsulfonamido）methyl}cyclohexanecarboxylic acid（C14H18N2O6s）, has been synthesized by the reaction of tranexamic acid and 4-nitrobenzenesulfonyl chloride in basic medium at room temperature. The molecular structure was determined by FT-IR, NMR, elemental analysis and single-crystal X-ray technique. X-ray diffraction shows that the compound crystallizes in the monoclinic system, space group P21/c with a = 13.5980（7）, b = 4.9877（2）, c = 23.3878（13） A, β = 93.254（3）°, z = 4, V = 1583.67（14） A3, μ = 0.237 mm-1, F（000） = 720, R = 0.0471 and w R = 0.1182. The molecules are related by inversion and paired into dimers via C–H…O interactions. The dimmers are interlinked due to strong N–H…O bonds, where O-atoms are of sulfonyl groups. The molecules are stabilized in the form of infinite two-dimensional network with base vectors [0 1 0] and [0 0 –1] in the plane（1 0 2）. The existence of good intermolecular interactions suggests the biological importance of the synthesized molecule. The compound was screened for its interaction with Fs-DNA using UV-visible spectroscopy. UV-visible spectroscopic results depict that the compound interacts with DNA by mixed binding mode intercalation along with hydrogen bonding. Negative values of ΔG（–23.34, –17.79 k J·mol-1） indicate spontaneity of the compound-DNA adduct formation.

关键词： sulfonamide tranexamic acid 4-nitrobenzenesulfonyl chloride XRD Fs-DNA,intercalation

4-((4-Chlorophenylsulfonamido)methyl)cyclohexanecarboxylic Acid： synthesis, Crystal structure and Biological Activities

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Chinese Journal of structural Chemistry 2017年第8期36卷 1307-1314页

作者： MUHAMMAD Danish RABIA Ayub butt MUHAMMAD Nawaz Tahir MUHAMMAD Ashfaq sYEDA Tahira Hafeez MUHAMMAD Naeem Ahmed HALEEMA Qureshi Department of Chemistry University of Gujrat Gujrat 50700 Pakistan Department of Physics University of Sargodha Sargodha Pakistan Department of Chemistry University of Azad Jammu and Kashmir Muzaffarabad 13100 Pakistan

In this study, a novel 4-（（4-chlorophenylsulfonamido）methyl）cyclohexanecarboxylic acid（C（14）H（18）ClNO4s） was synthesized by the reaction of tranexamic acid and 4-chlororbenzene sulfonyl chloride in basic medium at room temperature. The molecular structure was determined by FT-IR, NMR, elemental analysis and single-crystal X-ray analysis. The compound crystallizes in the monoclinic system, space group P21/c with a = 12.3120（11）, b = 16.5987（19）, c = 7.6873（7）？, β = 90.495（6）o, z = 4 and V = 1570.9（3）？~3, crystal size（mm） = 0.38 × 0.16 × 0.14 and Rint = 0.045. In this compound, the carboxylic acid A（O（1）/C（1）/C（2）） and the sulfonyl B（O（3）/s（1）/O（4）） moieties are of course planar. The molecules are dimerized due to the O–H…O type of H-bonding with the R22（8） ring motifs. The dimmers are interlinked through C–H…O and N–H…O types of H-bonding. The synthesized compound was screened against four bacterial and two fungal strains and inactive against all strains. Antioxidant activity was checked against DPPH. Enzyme inhibition activity was carried out using three different enzymes and the title compound was more potent α-chymotrypsin inhibitor.

关键词： sulfonamide tranexamic acid 4-chlorobenzenesulfonyl chloride XRD biological applications

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康德政治著作选

selection and screening of superior Genotypes for Quality Planting stock Based on Vegetative Growth Performance of some selected 12-Year-Old Acacia species

丛书名：剑桥政治思想史丛书

2013年

作者：（英）H.s.赖斯（H.s.Reiss）编金威译

本部广受赞誉的伊曼努尔·康德政治著作集首版于1970年，现经修改与增订交付剑桥政治思想史原著系列出版。其中有三篇文本是第一次翻译。除了扩展参考文献之外，赖斯教授又增补了一篇实质性的后记，以指出康德研究的新近进展，以及在增... 详细信息

ISBN: (纸本)9787562048275

本部广受赞誉的伊曼努尔·康德政治著作集首版于1970年，现经修改与增订交付剑桥政治思想史原著系列出版。其中有三篇文本是第一次翻译。除了扩展参考文献之外，赖斯教授又增补了一篇实质性的后记，以指出康德研究的新近进展，以及在增进我们对康德政治思想的认识中，这些进展所引起的那些变化。在他的一般性导言中，赖斯教授将翻译的文本与欧洲启蒙运动宽广的智识背景以及康德自己的道德哲学和历史哲学著作联系起来，勾勒了康德政治哲学的中心要旨。

关键词：康德I. 1724 1804 思想政治著作

来源：汇雅图书（南通市图书馆... 评论

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Open Journal of Forestry 2016年第4期6卷 217-229页

作者： M. sures Kumar N. Parameswari C. F. Chin z. Baharum K. K. Olalekan A. s. Nor Aini Department of Forest Management Faculty of Forestry Universiti Putra Malaysia Serdang Malaysia Department of Cell and Molecular Biology Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia Serdang Malaysia school of Biosciences Faculty of Science University of Nottingham Malaysia Campus Semenyih Malaysia Institute of Tropical Forestry and Forest Product Universiti Putra Malaysia Serdang Malaysia Institute of Tropical Agriculture Universiti Putra Malaysia Serdang Malaysia

Production of quality wood is a big problem in forestry plantation since trees grown in plantation of some high value temperate and tropical hardwood species tend to produce low value, short butt logs and bolts due to crooked stems, low fork heights and delayed shedding of lower branches. Result from existing Acacia plantation in Malaysia indicated that most existing Acacia plantation trees especially Acacia auriculiformis and Acacia mangium, fork very heavily which leads to the formation of multiple leaders more than one and some are fork so close to the ground that they will produce little to no merchantable wood. In this context, a research study was initiated to select and recommend the best performing tree species or provenance suited for timber production in Malaysia with respect to growth and other characteristics. species/provenance/progeny test was conducted on four species of Acacia namely, A. mangium, A. auriculiformis, A. crassicarpa and A. aulococarpa, each with 4 provenances originated from Papua New Guinea (PNG) and Queensland (QL). The growth performance of the provenances was monitored in terms of some quantitative and qualitative characteristics to evaluate the genetic variation and growth performance of a base breeding population. 20 progenies for each species were selected and randomly planted with 16 trees representing each progenies in a trial plot laid out in a randomized complete block design consisting of four blocks as replication. The study showed that there were significant different (p mangium performed better compared to other Acacia species in all of the aspect tested and it was followed by A. crassicarpa, A. aulococarpa and A. auriculiformis. There were also significant differences between provenance within regions and progenies within provenances in all quantitative and qualitative traits tested in this study. Generally, provenance and progenies selected from PNG excelled those from QL both in quantitative and qualitative characteris

关键词： Growth Performance Provenance-Progeny Trial Acacia sp Tree Improvement Plantation Management

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中国儿童川崎病诊疗循证指南(2023年)

中国当代儿科杂志 2023年第12期25卷 1198-1210页

作者：陕西省川崎病诊疗中心/陕西省人民医院儿童病院国家儿童医学中心/首都医科大学附属北京儿童医院上海交通大学医学院附属儿童医院国家区域医疗中心/中国医科大学附属盛京医院国家临床重点专科/上海市儿童医院重症医学科中国医师协会儿科医师分会普儿科学组中国妇幼健康研究会儿科能力建设专家委员会国家卫生健康委员会热带病防治重点实验室延安大学附属医院《中国当代儿科杂志》编辑焦富勇杜忠东黄玉娟李夙凌田园杨晓东王虹不详陕西省川崎病诊疗中心/陕西省人民医院儿童病院国家儿童医学中心/首都医科大学附属北京儿童医院上海交通大学医学院附属儿童医院急诊科延安大学附属医院儿科上海交通大学医学院附属儿童医院健康管理科上海交通大学医学院附属儿童医院心内科国家区域医疗中心/中国医科大学附属盛京医院小儿心脏病科

川崎病(Kawasaki disease,kd)是一种急性自限性血管炎性疾病,是引起5岁以下儿童后天获得性心脏病的最常见原因。国家卫生健康委员会发布的2023年儿科质控工作改进目标之一是降低kd患儿心脏事件的发生率及kd相关病死率。为规范我国kd的... 详细信息

川崎病(Kawasaki disease,kd)是一种急性自限性血管炎性疾病,是引起5岁以下儿童后天获得性心脏病的最常见原因。国家卫生健康委员会发布的2023年儿科质控工作改进目标之一是降低kd患儿心脏事件的发生率及kd相关病死率。为规范我国kd的诊断、治疗和长期管理实践,有效预防、减少冠状动脉病变的发生及远期不良影响,指南工作组遵循世界卫生组织指南制订的原则和方法,参照现有国内外证据和经验形成了《中国儿童川崎病诊疗循证指南(2023年)》。该指南针对kd的分类及定义、不同类型kd的诊断、kd急性期治疗、超声心动图在kd并发症识别中的应用和kd合并巨噬细胞活化综合征的处理等临床问题,基于最佳证据和专家共识形成了20条推荐意见,以期为广大医护人员在儿童kd的诊断与治疗方面提供指导与决策依据。

关键词：川崎病临床实践指南诊断治疗儿童

Fibromodulin reduces scar formation in adult cutaneouswounds by eliciting a fetal-like phenotype

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signal Transduction and Targeted Therapy 2017年第1期2卷 73-84页

作者： zhong zheng Aaron W James Chenshuang Li Wenlu Jiang Joyce z Wang Grace X Chang Kevin s Lee Feng Chen Emily A Berthiaume Yao Chen Hsin Chuan Pan Eric C Chen Weiming Li zhihe zhao Xinli zhang Kang Ting Chia soo Division of Growth and Development School of DentistryUniversity of CaliforniaLos AngelesLos AngelesCA 90095USA UCLA Division of Plastic and Reconstructive surgery Department of Orthopaedic SurgeryThe Orthopaedic Hospital Research CenterUniversity of CaliforniaLos AngelesLos AngelesCA 90095USA Department of Pathology Johns Hopkins UniversityBaltimoreMD 21287USA state Key Laboratory of Oral Diseases Department of OrthodonticsWest China School of StomatologySichuan UniversityChengduSichuan 610041China Department of Emergency Medicine Highland General HospitalOaklandCA 94602USA David Geffen school of Medicine University of CaliforniaLos AngelesLos AngelesCA 90095USA Central Laboratory School of StomatologyPeking UniversityBeijing 100081China Department of Orthopaedics the First Clinical Hospital of Harbin Medical UniversityHarbinHeilongjiang 150081China

Blocking transforming growth factor(TGF)β1 signal transduction has been a central strategy for scar reduction;however,this approach appears to be minimally ***,we show that fibromodulin(FMOD),a 59-kd small leucine-rich proteoglycan critical for normal collagen fibrillogenesis,significantly reduces scar formation while simultaneously increasing scar strength in both adult rodent models and porcine wounds,which simulate human cutaneous scar ***,FMOD uncouples promigration/contraction cellular signals from pro-fibrotic signaling by selectively enhancing sMAD3-mediated signal transduction,while reducing AP-1-mediated TGFβ1 auto-induction and fibrotic extracellular matrix ***,FMOD accelerates TGFβ1-responsive adult fibroblast migration,myofibroblast conversion,and ***,our findings strongly indicate that,by delicately orchestrating TGFβ1 activities rather than indiscriminately blocking TGFβ1,FMOD elicits fetal-like cellular and molecular phenotypes in adult dermal fibroblasts in vitro and adult cutaneous wounds in vivo,which is a unique response of living system undescribed *** together,this study illuminates the signal modulating activities of FMOD beyond its structural support functions,and highlights the potential for FMOD-based therapies to be used in cutaneous wound repair.

关键词： fetal scar cutaneous

纳米znTe插层对Cu_(2-x)se硫属化合物热电性能的增强效应（英文）

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science China Materials 2016年第2期59卷 135-143页

作者： Muhammad Umer Farooq sajid butt 高克玮孙喜贵庞晓露 Asif Mahmood Waqar Mahmood sajid U.Khan Nasir Mahmood school of Materials science and Engineering University of Science and Technology Beijing Department of Materials science and Engineering Institute of Space Technology state Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University Department of Material science and Engineering College of Engineering Peking University Department of Physics Thin Film Technology (TFT) Research LaboratoryCOMSATS Institute of Information Technology Department of Materials science and Engineering Institute of Space Technology Institute of superconducting and Electronic Materials Australian Institute of Innovative MaterialsUniversity of Wollongong

由于具有复杂的晶体结构和超离子导体行为,金属硫属化合物特别是Cu2-xse在热电领域得到了广泛的关注.本文报道了一种简单易行的提高热电效率的方法:在基体材料Cu2-xse中添加纳米zn Te插层,用来提高Cu2-xse材料的热电性能.实验结果表明,C... 详细信息

由于具有复杂的晶体结构和超离子导体行为,金属硫属化合物特别是Cu2-xse在热电领域得到了广泛的关注.本文报道了一种简单易行的提高热电效率的方法:在基体材料Cu2-xse中添加纳米zn Te插层,用来提高Cu2-xse材料的热电性能.实验结果表明,Cu2-xse-zn Te复合材料的电导率提高了32%,电导率的增加牺牲了塞贝克系数,导致复合材料的功率因子稍微低于纯Cu2-xse基体材料;第二相的引入抑制了晶格热扩散,使得Cu2-xse-zn Te复合材料的热导率降低了34%.由此可知,适中的功率因子和较低的热导率致使含有10 wt.%zn Te的Cu2-xse-zn Te复合材料在中温条件(750 K)下的z T值提高至0.40,相比于纯Cu2-xse基体材料该数值提高了40%.因此,向Cu2-xse材料中添加纳米zn Te插层,是提高Cu2-xse基材料热电性能的一个有效途径.

关键词： znTe nanoparticles Cu2s thermoelectric materialas Cu2-xse-znTe composite thermal conductivity

Kimura disease:review of the literature

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Kimura disease:review of the literature