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New indication area in intersphincteric resection:transanal total mesorectal excision combined with intersphincteric resection

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Gastroenterology Report 2023年第1期11卷 606-607页

作者： bulent Cavit Yuksel Department of Colon&Rectum General SurgeryAnkara Bilkent City HospitalUniversity of Health ScienceAnkaraTurkey

We read the article by Liu et al.[1]entitled“Transanal total mesorectal excision combined with intersphincteric resection has similar long-term oncological outcomes to laparoscopic abdominoperineal resection in low rectal cancer:a propensity scorematched cohort study.”The article is very interesting and boldly ***,I noticed some areas of the article that I could not find the answers to.

关键词： resection rectal sphincter

Minimally invasive techniques in benign and malignant adrenal tumors

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World Journal of Clinical Cases 2022年第35期10卷 12812-12821页

作者： Ahmet bulent Dogrul Omer Cennet Anıl Hilmi Dincer Department of General Surgery Hacettepe University Faculty of MedicineHacettepe UniversityAnkara 06100Turkey

Minimally invasive adrenalectomy has become the main treatment modality for most adrenal *** laparoscopic transabdominal and retroperitoneoscopic approaches are safe and feasible options,each with respective advantages,including better surgical outcomes,fewer complications,and faster recovery over open *** open surgery remains a valid modality in treatment of adrenocortical cancer in the presence of some findings such as invasion,robotic platforms,and minimally invasive surgery have gained popularity as technology continues to *** preservation during adrenalectomy is feasible in some conditions to prevent adrenal *** technologies are increasingly utilized in benign and malignant tumors,including the adrenal gland,with various outcomes.A multidisciplinary team,an experienced surgeon,and a highvolume center are recommended for any surgical approaches and management of adrenal *** review article evaluated recent findings and current evidence on minimally invasive adrenalectomy.

关键词： Adrenalectomy Laparoscopy Retroperitoneoscopic Minimally invasive surgery Robotic

Preparation and characterization of iron-ore-imbedded silicone rubber materials for radiation protection

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Nuclear Science and Techniques 2018年第9期29卷 230-235页

作者： bulent Buyuk Engineering Sciences Department Main CampusEngineering and Natural Sciences Faculty Bandirma Onyedi Eylul University

Iron-ore-imbedded silicone rubber materials were produced for radiation shielding. Samples were tested against a Co-60 gamma source, which is widely used in nuclear technology and medicine. Decreasing the particle size of iron ore resulted in better gamma radiation protection owing to more homogenous distribution. In addition, the materials had flexible properties up to the addition of 60 wt% iron ore content. Further, 0.5 mm Pb E gamma protection was provided by using 2.06-mm-thick SDT-60 as the Co-60 source. Iron ore–silicone rubber composites are candidate materials for lead-free flexible radiation protection systems owing to their relatively inexpensive and easy production.

关键词： Iron ore Silicone rubber Radiation shielding Co-60 Lead-free flexible materials Linear attenuation coefficients

Prognostic value of claudin 18.2 expression in gastric adenocarcinoma

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World Journal of Gastrointestinal Oncology 2023年第2期15卷 343-351页

作者： Erkan Kayikcioglu Ramazan Oğuz Yüceer bulent Cetin Kamuran Yüceer Nermin Karahan Department of Medical Oncology Suleyman Demirel UniversityIsparta 32260Turkey Department of Pathology Isparta City HospitalIsparta 32360Turkey Department of Internal Medicine Suleyman Demirel UniversityFaculty of MedicineIsparta 32360Turkey Department of Pathology Suleyman Demirel UniversityIsparta 32360Turkey

BACKGROUND Claudin 18.2(CLDN18.2)is a cell surface protein expressed by gastric cancer *** monoclonal antibody zolbetuximab binds CLDN18.2-positive cancer cells and causes cancer cell death.A few studies researched the prognostic effect of CLDN18.2 expression in metastatic gastric *** To identify the prognostic value of CLDN18.2 expression in patients with metastatic gastric *** This study was conducted with 65 patients over the age of 18 who were diagnosed with metastatic gastric *** investigated the effect of CLDN18.2 expression on clinicopathological characteristics(age,sex,histological grade,Lauren classification,family history,metastatic site,HER2 expression)and prognosis for patients with metastatic gastric *** CLDN18.2 expression was positive in 73.8%(48)of the *** the median 17.7-mo follow-up period,89.2%(58)of the patients *** progression-free survival and overall survival(OS)were 6 mo(95%confidence interval:1.6-10.4)and 12 mo(95%confidence interval:7.5-16.5).There was no statistically significant correlation between CLDN18.2 expression and clinicopathological characteristics of the *** univariate and multivariate Cox regression analysis,there was no correlation between clinicopathological characteristics of patients and progression-free survival or *** CLDN18.2 expression was quite high in patients with gastric adenocarcinoma,identifying the proportion of the patients in whom zolbetuximab would be *** is no statistically significant correlation with clinicopathological characteristics and ***18.2 is not a prognostic marker in patients with gastric adenocarcinoma,although it is predictive.

关键词： Gastric adenocarcinoma Claudin 18.2 Overall survival Clinicopathological characteristics

Social media video analysis methodology for sarin exposure

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Forensic Sciences Research 2022年第2期7卷 279-284页

作者： Sadik Toprak Emine Yilmaz Can bulent Altinsoy John Hart Zekeriya Dogan Mustafa Ozcetin Department of Forensic Medicine Istanbul UniversityIstanbulTurkey Department of Medical Pharmacology Bulent Ecevit UniversityZonguldakTurkey Department of Pulmonary Medicine Bulent Ecevit UniversityZonguldakTurkey James Martin Center for Nonproliferation Studies MontereyCAUSA Department of Civil Engineering Bulent Ecevit UniversityZonguldakTurkey Department of Pediatrics Istanbul UniversityIstanbulTurkey

As social media becomes increasingly ubiquitous,many events are recorded and released on social media platforms,including chemical weapon *** develop an objective tool in order to evaluate brief and unstructured social media videos for analysing sarin exposure from a civilian medical pathology *** developed and validated this new questionnaire using a standardized procedure that includes content domain specification,item pool generation,content validity evaluation,a pilot study,and assessment of reliability and *** total,51 sarin attacks and 48 matched videos were ***’s a for all 20 items was 0.75,which indicates adequate internal *** test–retest reliability was 0.96,which indicates good internal *** inter-observer intraclass correlation coefficient was *** verifying sampling adequacy with the Kaiser–Meyer–Olkin measure and the factorability of the items with Barlett’s test of sphericity,a factor analysis was *** to the principal axis factoring,a six-factor solution explained 51.86%of the total *** receiver-operating characteristic curve analysis showed that the Video Score Questionnaire has a sensitivity of 0.817,a specificity of 0.478,and an efficiency of ***,the Video Score Questionnaire is reliable and valid for evaluating sarin attacks from brief and unstructured social media videos.

关键词： Forensic sciences social media sarin scale questionnaire chemical weapon nerve agent YouTube

Learning distance effect on lignite quality variables at global and local scales

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International Journal of Coal Science & Technology 2021年第5期8卷 856-868页

作者： Cem Yaylagul bulent Tutmez Dodurga Control Directorate Turkish Coal Enterprises(TKI)CorumTurkey Department of Mining Engineering Inonu UniversityMalatyaTurkey

Determining scale and variable effects have critical importance in developing an energy resource *** study aims to explore the relationships in heterogeneous lignite sites using different scale models,spatial weighting as well as error-based pair-wise *** a statistical learning framework,the relationships among the quality variables such as geochemical variables and the contributions of the coordinates to quality measures have been exhibited by generalized additive *** this way,the critical roles of spatial weights provided by the coordinates have been specified at a global *** experimental studies reveal that incorporating the geological weighting in the models as the additional information improves both accuracy and *** relationships among lignite quality variables and sampling locations are spatially non-stationary,the local structure and interdependencies among the variables were analyzed by geographically weighting *** local analyses including spatial patterns of bandwidths,search domains as well as residual-based areal dependencies provided not only the critical zones but also availability of pair-wise model alternatives by calibrating a model at each point for location-specific parameter *** results completely show that the weighting models applied at different scales can take spatial heterogeneity into consideration and these abilities provide some meta-data and specific information using in sustainable energy planning.

关键词： Lignite Distance effect Exploration Generalized Additive Model(GAM) Geographically Weighted Regression(GWR)

Comparative New Insight into the Tectonic Origin of Folds and Thrust Faults of an Extensional Basin: Soke-Kusadasi Basin, Aegean, Western Turkey

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Journal of Earth Science 2020年第3期31卷 582-595页

作者： bulent Dogan Department of Geological Engineering Engineering FacultyUniversity of KocaeliUmuttepe CampusIzmit-Kocaeli 41001Turkey

The Aegean area of the western Anatolian region of Turkey,controlled by the low-angle detachment normal fault system,forms an extensional province,the West Anatolian Extensional Province(WAEP).The tectonic deformation which occurred in the Miocene Period,including the Plio–Quaternary Period has created different structures in both the basement rocks and intra-basin deposits of the *** of these structures,high-angle normal faults,controls the supradetachment Soke-Kusadasi Basin(SKB).Within this basin,there are folds with different axes and thrust faults with a north-northwestnortheast(N,NW,NE)*** folds and thrust faults in the SKB deformed the sedimentary structures of intra-basin *** folds and thrust faults,which caused the rotation of beddings and imbrications in the SKB,are mainly associated with the tectonic process of the low angle detachment normal fault,which affected the SKB and the Aegean part of western *** the SKB,during the process of extensional deformation associated with primary low angle detachment normal faulting,the ramp-flat and inversion geometry observed in the basement rocks and basin deposits of the crust caused folds and thrust faults in only intra-basin *** the WAEP,it is determined for the first time that the folds and thrust faults causing limited shortening deformed the Plio–Quaternary sediments.

关键词： low angle detachment normal fault high angle normal fault fold thrust fault bedding extensional supradetachment basin

Interfacial Microstructure of Diffusion Bonded Inconel 738 and Ferritic Stainless Steel Couple

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Journal of Materials Science & Technology 2009年第4期25卷 527-530页

作者： bulent Kurt Mustafa Ulutan Bartin University Faculty of EngineeringDept.of Metallurgical and Materials Engineering University of Eskisehir Osmangazi Faculty of EngineeringDept. of Mech.Eng

In this study, Inconel 738 alloy was diffusion bonded to a ferritic stainless steel. The effect of bonding temperature on the microstructural development across the joint region was investigated. Following the diffusion bonding, conventional characterization techniques such as scanning electron microscopy （SEM）, energy dispersive X-ray （EDX） and microhardness were used to examine the interracial microstructure. It was seen that bonding temperature was effective on the diffusion of Ni from Inconel 738 to ferritic stainless steel that affected the microstructure of the interface. Austenite phase was formed at the interface as a result of Ni diffusion from the Inconel 738 to the interface.

关键词： Diffusion bonding Inconel 738 Ferritic stainless steel Interface

Is enteroscopy necessary for diagnosis of celiac disease?

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World Journal of Gastroenterology 2012年第31期18卷 4095-4101页

作者： Taylan Kav bulent Sivri Hacettepe University School of Medicine Department of MedicineDivision of GastroenterologySihhiyeAnkara 06100Turkey

Celiac disease(CD) is an autoimmune inflammatory disease of the small intestine as a result of reaction to wheat protein,*** of dietary gluten is the mainstay of the treatment that necessitates a precise diagnosis of the *** screening may aid in identifying patients with suspected CD,which should be confirmed by intestinal *** has been shown that duodenal biopsies are good for detection of the disease in most ***,there is a group of patients with positive serology and inconclusive *** a result of the widespread use of serology,many patients with equivocal findings grow *** current endoscopic methods can only diagnose villous atrophy,which can be present in the later grades of disease(i.e.,Marsh Ⅲ).To diagnose CD correctly,going deeper in the intestine may be *** can reveal changes in CD in the intestinal mucosa in 10%-17% of cases that have negative histology at initial *** of the method limits its *** endoscopy may be a good substitute for ***,both techniques should be reserved for patients with suspected diagnosis of *** paper reviews the current literature in terms of the value of enteroscopy for diagnosis of CD.

关键词：诊断小肠疾病检查腹腔自身免疫性血清学小麦蛋白