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ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de Matos Rodrigues Walmer bruno Rocha Martins Victor Pereira de Oliveira Myriam Suelen da Silva Wanzerley Hélio Brito dos santos Júnior francisco de Assis Oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

Enhancement of the Antigenotoxic and Antioxidant Actions of Eugenol from Spice Clove and the Stabilizer Gum Arabic on Colorectal Carcinogenesis

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Food and Nutrition Sciences 2024年第1期15卷 71-100页

作者： Nayanna de Oliveira Ramos Melo Lucas Gabriel da Costa Marques Humberto Maia Costa Neto Matheus De Sousa Silva francisco Vagnaldo Fechine Jamacaru bruno Coêlho Cavalcanti Antônio Adailson De Sousa Silva Conceição Aparecida Dornelas Postgraduate Program in Medical-Surgical Sciences School of Medicine Federal University of Ceará Fortaleza Brazil School of Medicine Federal University of Ceará Fortaleza Brazil Nucleus of Research and Development of Medicines (NPDM) Laboratory of Pharmacology and Preclinical Research School of Medicine Federal University of Ceará Fortaleza Brazil Nucleus for Research and Development of Medicines (NPDM) National Laboratory of Experimental Oncology Federal University of Ceará Fortaleza Brazil Postgraduate Program in Pathology and Medical-Surgical Sciences School of Medicine Federal University of Ceará Fortaleza Brazil

Spices are defined as any aromatic condiment of plant origin used to alter the flavor and aroma of foods. Besides flavor and aroma, many spices have antioxidant activity, mainly related to the presence in cloves of phenolic compounds, such as flavonoids, terpenoids and eugenol. In turn, the most common uses of gum arabic are in the form of powder for addition to soft drink syrups, cuisine and baked goods, specifically to stabilize the texture of products, increase the viscosity of liquids and promote the leavening of baked products (e.g., cakes). Both eugenol, extracted from cloves, and gum arabic, extracted from the hardened sap of two species of the Acacia tree, are dietary constituents routinely consumed virtually throughout the world. Both of them are also widely used medicinally to inhibit oxidative stress and genotoxicity. The prevention arm of the study included groups: Ia, IIa, IIIa, Iva, V, VI, VII, VIII. Once a week for 20 weeks, the controls received saline s.c. while the experimental groups received DMH at 20 mg/kg s.c. During the same period and for an additional 9 weeks, the animals received either water, 10% GA, EUG, or 10% GA + EUG by gavage. The treatment arm of the study included groups Ib, IIb, IIIb e IVb, IX, X, XI, XII). Once a week for 20 weeks, the controls received saline s.c. while the experimental groups received DMH at 20 mg/kg s.c. During the subsequent 9 weeks, the animals received either water, 10% GA, EUG or 10% GA + EUG by gavage. The novelty of this study is the investigation of their use alone and together for the prevention and treatment of experimental colorectal carcinogenesis induced by dimethylhydrazine. Our results show that the combined use of 10% gum arabic and eugenol was effective, with antioxidant action in the colon, as well as reducing oxidative stress in all colon segments and preventing and treating genotoxicity in all colon segments. Furthermore, their joint administration reduced the number of aberrant crypts and th

关键词： Eugenol Gum Arabic Carcinogenesis Oxidative Stress Genotoxicity

Resampling in neural networks with application to spatial analysis

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Geo-Spatial Information Science 2022年第3期25卷 413-424页

作者： bruno Póvoa Rodrigues Vinicius francisco Rofatto Marcelo Tomio Matsuoka Talita Teles Assunção Graduate Program in Agriculture and Geospatial Information Federal University of UberlândiaMonte CarmeloBrazil Institute of Geography Federal University of UberlândiaMonte CarmeloBrazil

In developing Artificial Neural Networks(ANNs),the available dataset is split into three categories:training,validation and ***,an important problem arises:How to trust the predic-tion provided by a particular ANN?Due to the randomness related to the network itself(architecture,initialization and learning procedure),there is usually no best *** this issue,we provide a framework,which captures the randomness related to the network *** idea is to perform several training and test trials based on the Jackknife resampling *** consists of iteratively deleting a single observation each time from the sample and recomputing the ANN on the rest of the sample ***,interval prediction is available instead of point *** proposed method was applied and tested using pH,Ca and P data obtained by analyzing 118 georeferenced soil *** results,based on the dataset size simulation,showed that 60%reduction in available dataset offers compatible accuracy in relation to full dataset,and therefore a higher cost of sampling in the field would not be *** re-sampling method spatially characterizes the points of greater or lesser accuracy and *** re-sampling method increased the success rate by using interval prediction instead of using the mean as the most probable *** we restrict it to the regression neural network model,the resampling method proposed can also be extended to other modern statistical tools,such as Kriging,Least Squares Collocation(LSC),Convolutional Neural Network(CNN),and so on.

关键词： Artificial Neural Network(ANN) data splitting resampling delete-1 Jackknife spatial analysis

A perspective on potassic and ultrapotassic rocks:Constraints on the Paleoproterozoic late to post-collisional event in the São francisco paleocontinent

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Geoscience Frontiers 2022年第5期13卷 242-266页

作者： Samuel Moreira Bersan AndréDanderfer Craig Storey Henrique bruno Hugo Moreira francisco Abreu Cristiano Lana Leonardo Gonçalves Isabela Nahas Universidade Federal de Ouro Preto Departamento de GeologiaCampus Morro do CruzeiroOuro PretoMG CEP 35400-000Brazil University of Portsmouth School of the EnvironmentGeography and GeosciencesBurnaby BuildingBurnaby RoadPortsmouth PO13QLUK Tektos Research Group UERJ-Rio de Janeiro State UniversityBrazil Sustain Geologia Belo HorizonteBrazil

The late-to post-collisional stage in orogenic systems is characterized by the coeval existence of bimodal potassic to ultrapotassic magmatic activity related to partial melting of an enriched lithospheric mantle together with crustal derived *** this paper,we present new whole rock geochemical analyses combined with zircon and titanite U–Pb and zircon Hf isotopic data from potassic to ultrapotassic rocks from six plutons that occur within the Archean Itacambira-Monte Azul block(BIMA),to discuss their petrogenesis and the tectonic implications for the São francisco *** new U–Pb ages range from ca.2.06 Ga to 1.98 Ga and reveal long-lasting potassic magmatism within the BIMA,which is within the late-to-post-collisional stage of the São francisco paleocontinent *** ultrapotassic rocks are compatible with a fluid-related metasomatized mantle source enriched by previous subduction events,whereas the potassic rocks are bimodal and have a transitional shoshonitic to A-type *** rocks have a hybrid nature,possible related to the mixing between the mafic potassic/ultrapotassic rocks and high temperature crustal melts of the Archean continental *** results also show an increase of within-plate signature towards the younger potassic *** participation of an important Archean crustal component in the genesis of these rocks is highlighted by the common and occasionally abundant occurrence of Archean inherited *** Hf isotopic record shows that most of the zircon inheritance has dominantly subchondriticεHf(t)values,which fits a crustal reworking derivation from a similar Eo-to Paleoarchean precursor ***,the presence of juvenile 2.36 Ga zircon inheritance in an ultrapotassic sample reveal the existence of a hidden reservoir that is somewhat similar to the described for the Mineiro Belt in southern São francisco paleocontinent.

关键词： Late-to post-collisional Potassic-ultrapotassic rocks U–Pb dating São francisco paleocontinent Rhyacian-Orosirian orogenic system

Preoperative albumin-bilirubin score is a prognostic factor for gastric cancer patients after curative gastrectomy

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1125-1137页

作者： Daniel Jose Szor Marina Alessandra Pereira Marcus Fernando Kodama Pertille Ramos francisco Tustumi Andre Roncon Dias bruno Zilberstein Ulysses Ribeiro Jr Department of Gastroenterology Instituto do CancerHospital das Clinicas HCFMUSPFaculdade de MedicinaUniversidade de Sao PauloSao Paulo 01246000Brazil

BACKGROUND Albumin-bilirubin(ALBI)score is an indicator of liver dysfunction and is useful for predicting prognosis of hepatocellular ***,this liver function index has been used to predict prognosis in other ***,the significance of ALBI score in gastric cancer(GC)after radical resection has not been *** To evaluate the prognostic value of the preoperative ALBI status in patients with GC who received curative *** Patients with GC who underwent curative intended gastrectomy were retrospectively evaluated from our prospective *** score was calculated as follows:(log10 bilirubin×0.660)+(albumin×-0.085).The receiver operating characteristic curve with area under the curve(AUC)was plotted to evaluate the ability of ALBI score in predicting recurrence or *** optimal cutoff value was determined by maximizing Youden’s index,and patients were divided into low and high-ALBI *** Kaplan-Meier curve was used to analyze the survival,and the log-rank test was used for comparison between *** A total of 361 patients(235 males)were *** median ALBI value for the entire cohort was-2.89(IQR-3.13;-2.59).The AUC for ALBI score was 0.617(95%CI:0.556-0.673,P<0.001),and the cutoff value ***,211(58.4%)patients were classified as low-ALBI group and 150(41.6%)as high-ALBI *** age(P=0.005),lower hemoglobin level(P<0.001),American Society of Anesthesiologists classification III/IV(P=0.001),and D1 lymphadenectomy P=0.003)were more frequent in the high-ALBI *** was no difference between both groups in terms of Lauren histological type,depth of tumor invasion(pT),presence of lymph node metastasis(pN),and pathologic(pTNM)*** postoperative complication,and mortality at 30 and 90 days were higher in the high-ALBI *** the survival analysis,the high-ALBI group had worse disease-free survival(DFS)and overall survival(OS)compared to those with low-ALBI(P<0.001).

关键词： Stomach neoplasms Adenocarcinoma Albumin-bilirubin Biomarker Prognosis Survival

Is it possible to adopt the same oncological approach in urgent surgery for colon cancer?

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World Journal of Clinical Oncology 2022年第11期13卷 896-906页

作者： bruno Yuki Yoshida Raphael L C Araujo José francisco M Farah Alberto Goldenberg Goldenberg Department of Surgery Federal University of Sao PauloSao Paulo 04024-002Sao PauloBrazil Department of General and Oncological Surgery Sao Paulo State Employee HospitalSao Paulo 04029-000Sao PauloBrazil

BACKGROUND Locoregional complications may occur in up to 30%of patients with colon *** they are frequent events in the natural history of this disease,there should be a concern in offering an oncologically adequate surgical treatment to these *** To compare the oncological radicality of surgery for colon cancer between urgent and elective *** One-hundred and eighty-nine consecutive patients with non-metastatic colon adenocarcinoma were studied over two years in a single institution,who underwent surgical resection as the first therapeutic approach,with 123 elective and 66 urgent *** assessment of oncological radicality was performed by analyzing the extension of the longitudinal margins of resection,the number of resected lymph nodes,and the percentage of surgeries with 12 or more resected lymph *** clinicopathological variables were compared between the two groups in terms of sex,age,tumor location,type of urgency,surgical access,staging,compromised lymph nodes rate,differentiation grade,angiolymphatic and perineural invasion,and early *** There was no difference between the elective and urgency group concerning the longitudinal margin of resection(average of 6.1 in elective vs 7.3 cm in urgency,P=0.144),number of resected lymph nodes(average of 17.7 in elective vs 16.6 in urgency,P=0.355)and percentage of surgeries with 12 or more resected lymph nodes(75.6%in elective vs 77.3%in urgency,P=0.798).It was observed that the percentage of patients aged 80 and over was higher in the urgency group(13.0%in elective vs 25.8%in urgency,P=0.028),and the early mortality was 4.9%in elective vs 15.2%in urgency(P=0.016,OR:3.48,95%CI:1.21–10.06).Tumor location(P=0.004),surgery performed(P=0.016)and surgical access(P<0.001)were also different between the two *** was no difference in other clinicopathological variables *** Oncological radicality of colon cancer surgery may be achieved in both emergency and

关键词： Colorectal cancer Intestinal obstruction Intestinal perforation Surgical oncology Lymph node excision

Mangiferin,a natural xanthone,accelerates gastrointestinal transit in mice involving cholinergic mechanism

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World Journal of Gastroenterology 2012年第25期18卷 3207-3214页

作者： Talita Cavalcante Morais Synara Cavalcante Lopes Karine Maria Martins Bezerra Carvalho bruno Rodrigues Arruda francisco Thiago Correia de Souza Maria Teresa Salles Trevisan Vietla Satyanarayana Rao Flávia Almeida santos Department of Physiology and Pharmacology Brazilian SemiArid Institute of BiomedicineFaculty of MedicineFederal University of CearáFortaleza 60430-270Brazil Post-Graduate Programme in Medical Sciences Faculty of MedicineFederal University of CearáFortaleza 60430-140Brazil Department of Organic and Inorganic Chemistry Federal University of CearáFortaleza 60451-970Brazil

AIM:To investigate the effects of mangiferin on gastrointestinal transit(GIT) in normal and constipated mice,together with the possible ***:Intragastrically-administered charcoal mealwas used to measure GIT in overnight starved Swiss *** the first experiments,mangiferin(3 mg/kg,10 mg/kg,30 mg/kg,and 100 mg/kg,po) or tegaserod(1 mg/kg,ip) were administered 30 min before the charcoal meal to study their effects on normal *** the second series,mangiferin(30 mg/kg) was tested on delayed GIT induced by several different pharmacological agonists(morphine,clonidine,capsaicin) or antagonists(ondansetron,verapamil,and atropine) whereas in the third series,mangiferin(30 mg/kg,100 mg/kg and 300 mg/kg) or tegaserod(1 mg/kg) were tested on 6 h fecal pellets outputted by freely fed *** ratio of wet to dry weight was calculated and used as a marker of fecal water ***:Mangiferin administered orally significantly(P < 0.05) accelerated GIT at 30 mg/kg and 100 mg/kg(89% and 93%,respectively),similarly to 5-hydroxytryptamine4(5-HT4) agonist tegaserod(81%) when compared to vehicle-treated control(63%).Co-administered mangiferin(30 mg/kg) totally reversed the inhibitory effect of opioid agonist morphine,5-HT3-receptor antagonist ondansetron and transient receptor potential vanilloid-1 receptor agonist capsaicin on GIT,but only to a partial extent with the GIT-delay induced by 2-adrenoceptor agonist clonidine,and calcium antagonist ***,co-administered atropine completely blocked the stimulant effect of mangiferin on GIT,suggesting the involvement of muscarinic acetylcholine receptor *** mangiferin significantly enhanced the 6 h fecal output at higher doses(245.5 ± 10.43 mg vs 161.9 ± 10.82 mg and 227.1 ± 20.11 mg vs 161.9 ± 10.82 mg of vehicle-treated control,at 30 and 100 mg/kg,P < 0.05,respectively),the effect of tegaserod was more potent(297.4 ± 7.42 mg vs 161.9 ± 10.82 mg of vehicle-treated control,P < 0.05).Unlik

关键词：生理机制胃肠蠕动肾上腺素受体激动剂芒果小鼠氧杂蒽酮胆碱能受体拮抗剂

Nanocellulose: Effect on Thermal, Structural, Molecular Mobility and Rheological Characteristics of Poly(Butylenes Adipate-Co-Butylene Terephthalate) Nanocomposites

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Materials Sciences and Applications 2022年第4期13卷 249-277页

作者： Gerson Alberto Valencia Albitres francisco Pereira Araujo Junior Daniela França Silva Freitas Danielle Mattos Mariano Maria Ines bruno Tavares Luis Claudio Mendes Universidade Federal do Rio de Janeiro Instituto de Macromoléculas Professora Eloisa Mano Rio de Janeiro Brazil

The concern with environmental preservation is a very current and relevant topic. Regarding polymers, the search for potentially ecofriendly matters has been the subject of scientific research. In this context, this work aimed to study the effect of adding nanocellulose (nCE) with 1, 3, and 5 wt.% on poly(butylene adipate-co-butylene terephthalate) (PBAT). Thermal, structural, relaxometric, and rheological assessments were carried out. Quantitative evaluation of PBAT copolymer by high field NMR revealed 56.4 and 43.6 m.% of the butylene adipate and butylene terephthalate segments, respectively. WAXD measurement on the deconvoluted diffraction patterns identified that nCE was a mixing of Cellulose I and Cellulose II polymorph structures. At any composition, nanocellulose interfered with the PBAT crystallisation process. Also, a series of new PBAT crystallographic planes appeared as a function of nanocellulose content. PBAT hydrogen molecular relaxation varied randomly with nanocellulose content and had a strong effect on the hydrogen relaxation. PBAT cold crystallisation and melting temperatures (Tcc and Tm) were almost unchangeable. Although Tcc did not change during polymer solidification from PBAT molten state, the sample’s degree of crystallinity varied with composition through the transcrystallization phenomenon. Nanocomposite thermal stability decreased possibly owing to the catalytic action of sulfonated amorphous cellulose chains. For the sample with 3 wt.% of nanocellulose, the highest values of complex viscosity and storage modulus were achieved.

关键词： Nanocellulose Poly(Butylene Adipate-Co-Butylene Terephthalate) Molecular Relaxation Nanocomposite

A measure of ionospheric irregularities:zonal velocity and its implications for L-band scintillation at low-latitudes

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Earth and Planetary Physics 2021年第5期5卷 450-461页

作者： Claudio Cesaroni Luca Spogli Giorgiana De Franceschi Juliana Garrido Damaceno Marcin Grzesiak bruno Vani Joao francisco Galera Monico Vincenzo Romano Lucilla Alfonsi Massimo Cafaro Istituto Nazionale di Geofisica e Vulcanologia Italy SpacEarth Technology Italy Space Research Centre of the Polish Academy of Sciences Poland Instituto Federal de Educação Ciência e Tecnologia de São PauloBrazil Universidade Estadual Paulista“Júlio de Mesquita Filho” Brazil University of Salento Italy

We estimate the zonal drift velocity of small-scale ionospheric irregularities at low latitude by leveraging the spaced-receivers technique applied to two GNSS receivers for scintillation monitoring installed along the magnetic parallel passing in Presidente Prudente(Brazil,magnetic latitude 12.8°S).The investigated ionospheric sector is ideal to study small-scale irregularities,being located close to the expected position of the southern crest of the equatorial ionospheric *** measurement campaign took place between September 2013 and February 2014,*** and summer solstice seasons under solar maximum,during which the probability of formation of small-scale irregularities is expected to *** found that the hourly average of the velocity increases up to 135 m/s right after the local sunset at ionospheric altitudes and then smoothly decreases in the next *** measurements are in agreement with independent estimations of the velocity made by the Incoherent Scatter Radar located at the Jicamarca Radio Observatory(magnetic latitude 0.1°N),by the Boa Vista Ionosonde(magnetic latitude 12.0°N),and by applying a recently-developed empirical regional short-term forecasting ***,we investigated the relationship with the percentage occurrence of amplitude scintillation;we report that it is exponentially dependent on the zonal velocity of the irregularities that cause it.

关键词： ionospheric irregularities GNSS scintillation plasma drift velocity low-latitude ionosphere spaced receivers Equatorial Plasma Bubbles