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Asian Pacific Journal of Tropical Medicine 2016年第5期9卷 420-424页

作者： Silmara Baroni bruno ambrosio da rocha Juliana Oliveira de Melo Jurandir Fernando Comar Silvana Martins Caparroz-Assef Ciomar Aparecida Bersani-Amado Department of Pharmacology and Therapeutic State University of MaringaParanaBrazil Department of Biochemistry State University of MaringaParanaBrazil

Objective: To evaluate the effect of hydroethanolic extract of yacon on the hyperglycemia induced by streptozotocin(STZ) in neonatal rats. Methods: Wistar rats aged two days old received an intraperitoneal injection of STZ(160 mg/kg); after seven weeks, glycosuria was determined and animals with glucose levels above 250 mg/d L were included in the study. Groups of diabetic and non-diabetic rats were treated orally with yacon extract at a dose of 400 mg/kg/d for 14 d. Tests were made for phytochemical characterization, glucose tolerance and toxicity. Results: The results showed that treatment with the extract reduced the glucose levels of fed diabetic rats and did not change the glucose levels of fasting diabetic and normal rats. Additionally, also it was observed that treatment with the extract reduced blood glucose levels of diabetic rats during the oral and intravenous glucose tolerance tests. There was no change in body weight, liver enzymes or mortality with yacon extract treatment. The phytochemical screening revealed the presence of caffeic acid, chlorogenic acid, ferulic acid and gallic acid. Conclusions: The data suggest that yacon extract reduces hyperglycemia, possibly by improving insulin sensibility through its phytochemicals constituents(phenolic compounds).

关键词： Yacon extract Hyperglycemia Insulin sensibility Streptozotocin

ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de Matos Rodrigues Walmer bruno rocha Martins Victor Pereira de Oliveira Myriam Suelen da Silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis Oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

Automatic detection and evaluation of sugarcane planting rows in aerial images

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Information Processing in Agriculture 2023年第3期10卷 400-415页

作者： bruno Moraes rocha Afonso Ueslei da Fonseca Helio Pedrini Fabrızzio Soares Instituto de Informa´tica Universidade Federal de Goia´sGoiaˆnia 74690-900GOBrazil Institute of Computing University of CampinasCampinas 13083-852SPBrazil

Sugarcane planting is an important and growing activity in ***,several techniques have been developed over the years to maximize crop productivity and profit,amongst them,processing of sugarcane field *** this sense,this research aims to identify and analyze crop rows and measure their gaps from aerial images of sugarcane *** this,a small Remotely Piloted Aircraft captured the images,generating orthomosaics of the areas for ***,each orthomosaic is classified with the K-Nearest Neighbor algorithm to segment regions of *** row orientation is estimated using the RGB gradient *** operations and computational geometry models are then used to detect and map rows and gaps along the planting row *** evaluate the results,crop rows are mapped and compared to manually taken *** technique obtained an error smaller than 2%when compared to gap length in crop rows from an orthomosaic with the area of 8.05 ha(ha).The proposed approach can map the positioning of the automatically generated row segments appropriately onto manually created ***,our method also achieved similar results when confronted with a manual technique for differing growth stages(40 and 80 days after harvest)of the sugarcane *** proposed method presents a great potential to be adopted in sugarcane planting monitoring。

关键词： Sugarcane Planting Rows Aerial Images Remotely Piloted Aircraft

Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis

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World Journal of Gastroenterology 2014年第28期20卷 9458-9467页

作者： bruno César da Silva Andre Castro Lyra Raquel rocha Genoile Oliveira Santana Post-graduate Program in Medicine and Health Federal University of Bahia Gastroenterology Department of the University Hospital Professor Edgard Santos Federal University of Bahia Gastro-Hepatology Service of Hospital S?o Rafael Department of Sciences of Nutrition School of NutritionFederal University of Bahia

Ulcerative colitis(UC)is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and *** hallmark clinical symptom of UC is bloody *** clinical course is marked by exacerbations and remissions,which may occur spontaneously or in response to treatment changes or intercurrent *** is most commonly diagnosed in late adolescence or early adulthood,but it can occur at any *** incidence of UC has increased worldwide over recent decades,especially in developing *** contrast,during this period,therapeutic advances have improved the life expectancy of patients,and there has been a decrease in the mortality rate over *** is important to emphasize that there is considerable variability in the phenotypic presentation of *** this context,certain clinical and demographic characteristics are useful in identifying patients who tend to have more severe evolution of the disease and a poor *** this group of patients,better clinical surveillance and more intensive therapy may change the natural course of the *** aim of this article was to review the epidemiology and demographic characteristics of UC and the factors that may be associated with its clinical prognosis.

关键词： Ulcerative colitis Incidence Prevalence Risk factors Predictive factors

Radiographic and tomographic description of marlin sucker Remora osteochir, Pisces: Echeneidae—preliminary data of one specimen

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Marine Life Science & Technology 2020年第3期2卷 246-251页

作者： AndréLuiz Veiga Conrado Renata Stecca lunes Carlos Eduardo Malavasi bruno Aline Tiemi Shiraishi rocha JoséRoberto Machado Cunha da Silva Laboratory of Evolutive Histophysiology Department of Cell and Developmental BiologyInstitute of Biomedical SciencesUniversity of Sao PauloAvenida ProfLineu Prestes1524Cidade UniversitariaSao Paulo 05508-000Brazil Laboratory of Immunological Techniques Applied to Morphophysiology School of Veterinary Medicine and Animal ScienceDepartment of SurgeryUniversity of Sao PauloAvenida Prof.Di.Orlando Marques de Paiva87.Cidade UniversitariaSao Paulo 05508-270Brazil

Remoras are commensal fish of various marine species,such as sharks,swordfishes,turtles,dolphins,manta rays and *** specimen of marlin sucker Remora osteochir was evaluated using computed tomography for skeletal digital reconstruction,digital radiology for general evaluation and bone counting,and the double contrast technique to distinguish coelomic *** radiographic images,it was possible to observe otoliths in the center of the neurocranium,to count 27 vertebrae,nine pairs of ribs,and to detect the presence of the hipural and epural bones near of the caudal *** double contrast images,it was possible to visualize the swim bladder,gills,heart,liver,stomach and *** the tomographic images and reconstructions,it was possible to identify the intercalar bones of the cephalic disc;the spine with vertebral bodies composed of neural arches and ventral ribs;and the pectoral girdle formed by posttemporal,cleithrum and scapulocoracoid *** was concluded that digital radiology and computed tomography were able to describe anatomical structures of marlin sucker *** without the need for dissection.

关键词： Teleost fish Double contrast Computed tomography Digital radiology Skeleton

ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Oral pharmacological treatment for patent ductus arteriosus in premature neonates with hemodynamic repercussions

林业研究（英文版） 2024年第1期 87页

作者： Julia Isabella de Matos Rodrigues Walmer bruno rocha Martins Victor Pereira de Oliveira Myriam Suelen da Silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis Oliveira

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Asian Pacific Journal of Tropical Medicine 2017年第11期10卷 1080-1083页

作者： Clarissa de Albuquerque Botura bruno Ambrósio da rocha Thiely Balensiefer Franciele Queiroz Ames Ciomar Aparecida Bersani-Amado Roberto Kenji Nakamura Cuman Department of Medicine Faculdade Uningá Department of Pharmacology and Therapeutics State University of Maringá Hospital Pharmacy at Santa Rita Hospital

Objective: To evaluate the efficacy of oral indomethacin, ibuprofen, and paracetamol in oral dosage form on patent ductus arteriosus(Pda) in premature neonates with significant clinical and hemodynamic repercussions(CHRs) and to determine the effect of these respective treatments on renal ***: A retrospective study of cases of Pda in premature neonates in the Neonatal Intensive Care Unit was conducted. The treatments consisted of indomethacin[0.2 mg/(kg$d), 3-day cycle], ibuprofen [10 mg/(kg$d) followed by 5 mg/(kg$d), 3-day cycle], and paracetamol(15 mg/kg every 6 h, 5-day cycle). The drugs were administered as an oral solution. The following variables were considered: gestational age,newborn weight at birth, Apgar score, diuresis, serum creatinine and urea levels, and serum electrolyte levels(sodium and potassium).Results: Treatment with indomethacin presented efficacy of 87.5% in closure of the ductus with a mean outcome period of 3.5 d. In premature neonates with CHRs and contraindications for indomethacin, the initial treatment with either ibuprofen or paracetamol failed to close the ductus. However, when this treatment was followed by indomethacin, closure occurred in 66.7% of the neonates, with an outcome period of9.66 d. The initial treatment with one cycle of ibuprofen followed by one or two cycles of paracetamol failed to close the ***: Oral indomethacin was effective for closure of the Pda in premature neonates with severe CHRs. Oral paracetamol or ibuprofen for Pda closure in premature neonates with severe CHRs and contraindications for indomethacin was ***, results in clinical improvements of neonates allowed the subsequent use of indomethacin and successful closure of the ductus. A significant reduction of diuresis occurred in neonates who were treated with indomethacin, either as a first-line treatment or after the failure of ibuprofen or paracetamol.

关键词： Patent ductus arteriosus Premature neonatal Indomethacin Ibuprofen Paracetamol

Obtaining morphometric variables from gullies using two methods of interpolation laser scanner data:the case study of Vassouras,Brazil

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Journal of Mountain Science 2020年第12期17卷 3012-3023页

作者： OLIVEIRA Carlos Magno Moreira de FRANCELINO Márcio rocha MENDONCA bruno Araujo Furtado de RAMOS Isabela Queiroz Instituto Federal do Norte de Minas Gerais-Campus Arinos Rodovia MG 202Km 407 s/nZona RuralArinos-MG38680-000Brazil Departamento de Solos Universidade Federal de VigosaAv.Peter Henry Rolfss/n-Campus UniversitarioViqosa-MG36570-900Brazil Departamento de Silvicultura Universidade Federal Rural do Rio de JaneiroBR 465 Km 07Seropedica-RJ23890-000Brazil Instituto do Meio Ambiente e dos Recursos Hidricos do Distrito Federal SEPN 511Bloco C70750-543BrasiliaDFBrazil

Gully erosion is a worldwide problem of land degradation and water quality,and it is also frequent in ***,anthropic influence is the major driver of gully *** study and monitor gullies it is necessary to use specific instruments and methods to obtain accurate *** objective of this study was to use Terrestrial Laser Scanning(TLS) to create digital elevation model(DEM) accurately and define morphometric variables that characterize gullies in a mountainous *** different interpolations were evaluated using the Topogrid and GridSurfaceCreate algorithms to elaborate *** profile for gullies was used to assess modeling *** DEM of the Gully 1(G1) from the Topogrid algorithm estimated soil loss of 49%,whereas the GridSurfaceCreate algorithm estimated a soil loss of97%,in a period of 1 *** estimated soil loss for the Gully 2(G2) was 14% from the Topogrid,and 8%from the GridSurfaceCreate *** GridSurfaceCreate algorithm underestimated the volume to area ratio for G2 due to a failure on interpolating a region of low point *** Topogrid algorithm represented better the terrain irregularities,as observed through the topographic profiles traced in three regions of G1 and *** analysis showed that the GridSurfaceCreate algorithm presented lower accuracy in estimating *** underestimation trend of this algorithm was also observed in *** gullies showed considerable soil losses,which may reduce the areas suitable for agricultural activities,and silting up of water *** Topogrid algorithm presented satisfactory results,denoting great potential to produce morphometric data of gullies.

关键词： Erosion process Interpolation algorithms Spatial statistics Digital Elevation Model Topographic profile

Potential of four marine-derived fungi extracts as anti-proliferative and cell death-inducing agents in seven human cancer cell lines

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Asian Pacific Journal of Tropical Medicine 2015年第10期8卷 782-790页

作者： Alice Abreu Ramos Maria Prata-Sena bruno Castro-Carvalho Tida Dethoup Suradet Buttachon Anake Kijjoa Eduardo rocha Interdisciplinary Center for Marine and Environmental Research(CIIMAR) CIMAR Associate Laboratory(CIMAR LA)University of Porto(U.Porto) ICBAS-Institute of Biomedical Sciences Abel Salazar University of Porto(U.Porto) Department of Plant Pathology Faculty of AgricultureKasetsart University

Objective:To evaluate the in vitro anticancer activity of crude ethyl acetate extracts of the culture of four marine-derived fungi Aspergillus similanensis KUFA 0013(E1),Neosartorya paulistemis KUFC 7897(E2),Neosartorya siamensis KUFA 0017(E4) and Talaromyces trachyspermus KUFC 0021(E3) on a panel of seven human cancer cell ***:Effects on cell proliferation,induction of DNA damage and cell death were assessed by MTT and clonogenic assays,comet assay and nuclear condensation assay,***:The proliferation of HepG2,HCTl 16 and A375 cells decreased after incubation with the extracts E2 and *** anti-proliterative effect was confirmed by morphologic alterations and by clonogenic *** extracts also induced cell death in HepG2 and HCT116 *** was used as a positive control and showed in vitro anticancer ***:This study demonstrated,for the first time,that extracts of Neosartorya paulistensis and Neosartorya siamensis have selective anti-proliferative and cell death activities in HepG2,HCT16 and A375 *** bioactivity of these extracts suggests a potential for biotechnological applications and substantiates that both should be further considered for the elucidation of the molecular targets and signal transduction pathways involved.

关键词： Anti-proliferative activity Antineoplastic agents

Environmental licensing of new transmission systems in brazil: framing criteria by environmental agency

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Global Energy Interconnection 2020年第5期3卷 423-429页

作者： Ricardo Abranches Felix Cardoso Junior Alessandra Schwertner Hoffmann Lillian Monteath Carolina Vasconcellos Salcedo Benoit Lagore bruno Busato rocha Agriculture and Environmental Engineering Department-Engineering School.Universidade Federal Fluminense.R.Passo da Pátria 156-237-São DomingosNiteróiRJ24210-240Brazil Water Resources and Environmental Engineering Department-Engineering School.Universidade Federal Fluminense.R.Passo da Pátria 156-209-São DomingosNiteróiRJ24210-240Brazil Electric Sector Study Group-Federal University of Rio de Janeiro(UFRJ)-Institute of Economics Red Beach Campus Av.Pasteur 250-UrcaRio de JaneiroRJ22290-240Brazil

The growing demand for electricity in large Brazilian cities and the distance to the region with the largest energy production have encouraged the construction of transmission lines thousands of kilometers long, crossing several states of the federation. Therefore, the heterogeneity of requirements in federal, state and district environmental laws tend to lead to uncertainty for the investor regarding procedures and investments necessary for the completion of the project, as well as the time that the requirements will take to be fulfilled. In the present study, we identify and compare the criteria used by the various environmental licensing agencies for classifying transmission system projects in the different procedures(simplified and ordinary) of environmental licensing. It was possible to expose the differences and demonstrate some inconsistencies in the legislation of some Brazilian states. In particular, we note an absence of proportionality between the licensing requirements and the expected environmental impacts for projects on the physical, biological and social environments. Additionally, it was identified subjectivity in the requirement for social participation through public hearings, demanded by the legislation for the projects classified in the ordinary procedure.

关键词： environmental licensing environmental permitting transmission lines Brazil