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Dietary stimulation of the endogenous somatotropic axis in weaner and growerfinisher pigs using medium chain triglycerides and cysteamine hydrochloride

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Journal of Animal Science and Biotechnology 2017年第2期8卷 405-416页

作者： David W.Miller Zoe prosser Edward Y.W.Chee Christian F.Hansen Frank R.Dunshea bruce p.mullan John R.pluske School of Veterinary and Life Sciences Murdoch UniversityMurdochWA6150Australia Department of Large Animal Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenGroennegaardsvej 21870 Frederiksberg CDenmark Melbourne School of Land and Environment University of MelbourneParkvilleVlC 3051Australia Department of Agriculture and Food Western Australia Bentley Delivery CenterLocked Bag4BentleyWA 6983Australia

Background： Three experiments were conducted to examine the overall hypothesis that addition of medium chain triglycerides（MCT） and cysteamine hydrochloride（CSH） into the diets of young and growing pigs would stimulate the endogenous somatotropic axis to improve growth and ***： In Experiment 1, weaner pigs were given either a 5 d dietary supplement of 5 % MCT（n = 8） or a control diet（n = 8）. MCT increased the plasma concentration of growth hormone（GH; p ＆lt; 0.05） and the GH secretagogue,ghrelin（p ＆lt; 0.05）. Additionally, the MCT treatment reduced scouring（p ＆lt; 0.05）, maintained villous height in the small intestine（p ＆lt; 0.05） and stabilised daily weight gain（p ＆lt; 0.05）, compared to the controls. Experiment 2compared the effects of 4 levels（0, 1, 3 and 6 % v/v） of MCT supplementation in grower-finisher male pigs, of approximately 35 kg live weight（n = 15 per treatment）. Blood samples taken after 7 wk of treatment showed that the MCT supplementation increased circulating ghrelin（p ＆lt; 0.001）, GH（p ＆lt; 0.01） and insulin（p ＆lt; 0.05）concentrations in a dose-dependent manner. Daily weight gain, feed intake and feed conversion ratio were not affected by the MCT diets. In Experiment 3, 64 female pigs of approximately 60 kg live weight were allocated to one of three dietary treatments： control（n = 20）; 6 % MCT（n = 21）; and 70 mg/kg CSH（n = 21）. After 3 wk of supplementation, the MCT treated pigs had a higher plasma concentration of ghrelin compared to the control and CSH pigs（p ＆lt; 0.05）. plasma concentrations of GH and weight were not affected by any of the dietary ***： Evidence is provided in Experiment 1 to support the use of dietary MCT supplements, perhaps acting via stimulation of somatotropic endocrine pathways, to minimise weaning-associated disorders such as slowing of growth and diarrhoea. In Experiments 2 and 3, although there was no effect on weight gain or feed conversion ratio in either experiment, MCT and CSH incr

关键词： Ghrelin Growth pig Somatotropin

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日粮中添加中链甘油三酯和半胱胺酸盐对断奶仔猪和生长育肥猪内源性生长轴的影响

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猪业科学 2016年第12期33卷 24-26页

作者：孟春春(译) david w.miller zoe prosser edward y.w.chee christian f.hansen frank r.dunshea bruce p.mullan john r.pluske 北京百迈客生物科技有限公司北京101300 不详

该文通过3个试验来检验总体假设,即在仔猪和生长猪的日粮中添加中链甘油三酯(MCT)和半胱胺酸盐(CSH)将会刺激其内源性生长轴,从而改善其生长和性能。试验1结果显示:日粮中添加MCT增加了断奶仔猪血浆中生长激素(GH)(p<0.05)和生长激素促... 详细信息

该文通过3个试验来检验总体假设,即在仔猪和生长猪的日粮中添加中链甘油三酯(MCT)和半胱胺酸盐(CSH)将会刺激其内源性生长轴,从而改善其生长和性能。试验1结果显示:日粮中添加MCT增加了断奶仔猪血浆中生长激素(GH)(ppppppppp<0.05),而血浆GH浓度和体重则不受任何处理的影响。结论:试验1的结果表明日粮中添加MCT,可能是通过刺激生长激素内分泌途径将断奶相关病症(例如生长迟缓和腹泻)降到最低。在试验2和试验3中,尽管MCT和CSH的添加对猪只的增重或饲料转化率没有影响,但是增加了其生长轴的内分泌组分。

关键词： Ghrelin 生长猪促生长激素细胞

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Acetylsalicylic acid supplementation improves protein utilization efficiency while vitamin E supplementation reduces markers of the inflammatory response in weaned pigs challenged with enterotoxigenic ***

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Journal of Animal Science and Biotechnology 2017年第1期8卷 143-153页

作者： Jae Cheol Kim bruce p. mullan John L. Black Robert J. E. Hewitt Robert J. van Barneveld John R. pluske School of Veterinary and Life Sciences Murdoch University Murdoch WA 6150 Australia Department of Agriculture and Food Pork Innovation South Perth WA 6151 Australia John L Black Consulting Warrimoo NSW 2774 Australia Sunpork Farms Solutions Loganholme QLD 4129 Australia Barneveld Nutrition pry Ltd Loganholme QLD 4129 Australia

Background： This experiment was conducted to test the hypothesis that vitamin E（Vit E） and acetylsalicylic acid（ASA）, a cyclooxygenase-2（COX-2） inhibitor, will additively reduce the production of the immunosuppressive molecule prostaglandin E_2（pGE_2） and hence reduce inflammatory responses in weaner pigs experimentally infected with an enterotoxigenic strain of E. ***： The experiment was conducted in a research facility with 192 individually-housed male weaner pigs（Landrace × Large White） weighing 6.6 ± 0.04 kg（mean ± SEM）. The pigs were experimentally infected with an enterotoxigenic strain of E. coli and were allocated to a 2 × 3 factorial design with the respective factors being without and with 125 ppm ASA and three levels of Vit E supplementation（50, 100 or 200 IU/kg diet, dl-α-tocopheryl acetate）.Results： Acetylsalicylic acid supplementation improved average daily gain（p 〈 0.05） and tended to improve feed：gain ratio（p 〈 0.10） during the first 14 d after weaning. Acetylsalicylic acid supplementation also improved（p 〈 0.001） amino acid utilization efficiency（as assessed by plasma urea level） and tended to decrease（p 〈 0.10） pGE2 production in the liver without affecting smal intestinal histology and tight junction protein mR NA expression in the jejunal epithelium. Vitamin E supplementation greater than 100 IU/kg diet sustained both the plasma Vit E concentration（p 〈 0.001） and plasma haptoglobin content（p 〈 0.001） after weaning. However, there was no additive effects of the combined supplementation of ASA and Vit E on performance, intestinal barrier function and inflammatory responses of weaned ***： Although ASA and vitamin E improved amino acid utilization efficiency and reduced acute inflammatory responses, ASA and vitamin E did not additively reduce production of pGE2 and inflammatory responses in weaner pigs experimental y infected with an enterotoxigenic strain of E. coli.

关键词： Acetylsalicylic acid E.coli infection pGE_2 Vitamin E Weaner pigs

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Fracturing,caving propagation and influence of mining on groundwater above longwall panels–a review of predictive models

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International Journal of Mining Science and Technology 2020年第1期30卷 49-54页

作者： bruce Hebblewhite School of Minerals and Energy Resources Engineering University of New South WalesSydney 2052Australia

Historically there have been a number of different hypotheses and empirical models developed in an attempt to describe the nature of fracturing above longwall panels in underground coal *** motivation for suchmodels varies,ranging fromunderstanding the impact ofmining on surface subsidence,to back-analysis of caving behaviour in the immediate roof behind the longwall *** of the most critical motivating factors that is taking on increased importance in many coalfields,is the need for better understanding,and hence prediction of the impact of mining on overlying strata,particularly strata units acting as aquifers for different groundwater *** paper reviews some of the major prediction models in the context of observed behaviour of strata displacement and fracturing above longwall panels in the southern coalfields of New South Wales,south of *** paper discusses the parameter often referred to as"height of fracturing"in terms of the critical parameters that influence it,and the relevance and appropriateness of this terminology in the context of overlying sub-surface subsidence and groundwater *** paper proposes an alternative terminology for this parameter that better reflects what it is and how it is *** paper also addresses the potential role of major bedding shear planes mobilised by mining and their potential influence on overlying subsidence and groundwater interference.

关键词： Longwall mining Subsidence Groundwater Caving Underground coal mining

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From physics to fixtures to food:current and potential LED efficacy

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Horticulture Research 2020年第1期7卷 2271-2279页

作者： paul Kusuma p.Morgan pattison bruce Bugbee Crop physiology Laboratory Utah State UniversityLogan 84341 UTUSA Solid State Lighting Services Johnson City 37604 TNUSA

Overview Light-emitting diodes(LEDs)have enabled a historic increase in the conversion of electric energy to photons,but this is approaching a physical *** theoretical maximum efficiency occurs when all input energy is converted to energy in photosynthetic *** LEDs can be 93%efficient,phosphor-converted“whites”76%efficient,and red LEDs 81%*** improvements open new opportunities for horticultural lighting.

关键词： diodes phosphor approaching

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Study of Electron Beam Surfi-sculpt during Composite Materials Joining

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稀有金属材料与工程 2011年第S4期40卷 292-296页

作者： bruce Dance The Welding Institute(TWI) Cambridge CB1 6ALUK

Electron beam surfi-sculpt is a new metal surface processing technology,which is widely used in the areas of materials surface treatment,composite materials manufacturing,and so *** this paper,comeld technology,which was an application technology of electron beam surfi-sculpt during composite materials area,was *** tensile experiments results and failure forms of Ti6Al4V/Carbon fibre single step joints were compared with different joining methods,such as slick embedding,adhesive bonding,riveting and *** was found that comeld joint had more advantage of tensile property than other joining *** the same time,tensile process of comeld joint was analyzed with numerical simulation,and key factors of protrusions influenced tensile property were obtained,which was of importance to structure design and joint property improvement.

关键词： electron beam surfi-sculpt comeld joining methods tensile experiments numerical simulation

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微量元素与养猪生产（四）-平衡法则：微量元素需求与环境污染

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中国饲料添加剂 2010年第7期 15-17页

作者： bruce mullan 西澳大利亚大学农业和食品系澳大利亚QAF Meat Industries

随着养猪生产规模的日益增大，一个猪舍内饲养几千头猪是司空见惯的事。因此，人们越来越关注每年百万吨因生猪养殖而造成的氮、磷、钾的高浓度微量元素的污染排放问题。越来越多的呼声要求养猪业担当责任以降低因养猪生产的排放而造成... 详细信息

随着养猪生产规模的日益增大，一个猪舍内饲养几千头猪是司空见惯的事。因此，人们越来越关注每年百万吨因生猪养殖而造成的氮、磷、钾的高浓度微量元素的污染排放问题。越来越多的呼声要求养猪业担当责任以降低因养猪生产的排放而造成的污染。

关键词：养猪生产环境污染微量元素法则平衡排放问题生产规模生猪养殖

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A review of the geomechanics aspects of a double fatality coal burst at Austar Colliery in NSW,Australia in April 2014

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International Journal of Mining Science and Technology 2017年第1期27卷 3-7页

作者： Hebblewhite bruce Calvin Jim School of Mining Engineering UNSWSydney 2052Australia

A coal burst occurred on 15 April, 2014 at the Austar Coal Mine, located west of Newcastle, NSW,Australia. The burst resulted in fatal injuries to two men working as part of the mining crew at the development face. At the time, a continuous miner was being used to mine a longwall development gate road through heavily structured coal, at a depth of approximately 550 m. A number of pre-cursor bumps had occurred on previous shifts, emanating from the coal ribs of the roadway, in proximity to the coal *** paper reviews the geological, geotechnical and mining conditions and circumstances leading up to the coal burst event; and presents and discusses the available evidence and possible interpretations relating to the geomechanical behaviour mechanisms that may have been critical factors in this incident. The paper also discusses some key technical and operational considerations of ground support systems and mining practices and strategies needed for operating in such conditions in the future.

关键词： Underground coal mining Roadway development Strata controlCoal burst Coal geology Mine safety

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Biology past and Biology Future:Where have we been and where are we going?

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Neural Regeneration Research 2013年第25期8卷 2309-2316页

作者： bruce Alberts Department of Biochemistry and Biophysics the University of California San Francisco

bruce Alberts, a prominent biochemist with a strong commitment to the improvement of science and mathematics education, serves as Editor-in-Chief of Science and as one of president Obama＇s first three Science Envoys. Alberts is also professor Emeritus in the Department of Biochemistry and Biophysics at the University of California, San Francisco, to which he returned after serving two six-year terms as the president of the National Academy of Sciences （NAS）.

关键词： Biology past and Biology Future

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Two different mathematical schemes for solving chemical dissolution-front instability problems in fluid-saturated rocks

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Science China(Technological Sciences) 2022年第1期65卷 147-156页

作者： ZHAO ChongBin HOBBS bruce ORD Alison Computational Geosciences Research Centre Central South UniversityChangsha 410083China Key Laboratory of Metallogenic prediction of Nonferrous Metals and Geological Environment Monitoring Ministry of EducationCentral South UniversityChangsha 410083China School of Earth and Environment The University of Western AustraliaCrawleyWA 6009Australia

Chemical dissolution-front instability(CDFI)problems usually involve multiple temporal and spatial scales,as well as multiple processes.A key issue associated with solving a CDFI problem in a fluid-saturated rock is to mathematically establish a theoretical criterion,which can be used to judge the instability of a chemical dissolution-front(CDF)propagating in the fluidsaturated *** theoretical paper deals with how two different mathematical schemes can be used to precisely establish such a theoretical criterion in a purely mathematical manner,rather than in a numerical simulation *** main distinguishment between these two different mathematical schemes is that in the first mathematical scheme,a curved surface coordinate system is used,while in the second mathematical scheme,a planar surface coordinate system is *** particular,all the key mathematical deduction steps associated with using these two different mathematical schemes are described and discussed in great *** main theoretical outcomes of this study have demonstrated that(1)two different mathematical schemes under consideration can produce exactly the same theoretical criterion;(2)the main advantage of using the first mathematical scheme is that the interface conditions at the curved interface between the downstream and upstream regions can be easily described mathematically;(3)the main advantage of using the second mathematical scheme is that the first-order perturbation equations of the CDFI problem can be easily described in a purely mathematical manner.

关键词： chemical dissolution theoretical analysis mathematical scheme front instability fluid-saturated rocks

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