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The influence of resistance exercise training prescription variables on skeletal muscle mass,strength,and physical function in healthy adults:An umbrella review

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Journal of Sport and Health Science 2024年第1期13卷 47-60页

作者： Jonathan C.mcleod Brad S.Currier Caroline V.Lowisz Stuart m.phillips Department of Kinesiology Faculty of ScienceMcMaster UniversityHamilton L8S4L8Canada

Purpose:The aim of this umbrella review was to determine the impact of resistance training(RT)and individual RT prescription variables on muscle mass,strength,and physical function in healthy ***:Following Preferred Reporting Items for Systematic Reviews and meta-Analyses(PRISmA)guidelines,we systematically searched and screened eligible systematic reviews reporting the effects of differing RT prescription variables on muscle mass(or its proxies),strength,and/or physical function in healthy adults aged>18 ***:We identified 44 systematic reviews that met our inclusion *** methodological quality of these reviews was assessed using A measurement Tool to Assess Systematic Reviews;standardized effectiveness statements were *** found that RT was consistently a potent stimulus for increasing skeletal muscle mass(4/4 reviews provide some or sufficient evidence),strength(4/6 reviews provided some or sufficient evidence),and physical function(1/1 review provided some evidence).RT load(6/8 reviews provided some or sufficient evidence),weekly frequency(2/4 reviews provided some or sufficient evidence),volume(3/7 reviews provided some or sufficient evidence),and exercise order(1/1 review provided some evidence)impacted RT-induced increases in muscular *** discovered that 2/3 reviews provided some or sufficient evidence that RT volume and contraction velocity influenced skeletal muscle mass,while 4/7 reviews provided insufficient evidence in favor of RT load impacting skeletal muscle *** was insufficient evidence to conclude that time of day,periodization,inter-set rest,set configuration,set end point,contraction velocity/time under tension,or exercise order(only pertaining to hypertrophy)influenced skeletal muscle adaptations.A paucity of data limited insights into the impact of RT prescription variables on physical ***:Overall,RT increased muscle mass,strength,and physical function compared to no ***

关键词： Hypertrophy Resistance training Resistance training prescription variables Strength Umbrella review

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采用Kalman滤波器的实时混合试验方法

采用Kalman滤波器的实时混合试验方法

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全国结构振动与动力学学术研讨会暨第四届结构动力学专业委员会会议

作者：吴斌史鹏飞 Billie F.Spencer brian m.phillips Chia-ming Chang 哈尔滨工业大学土木工程学院中国建筑股份有限公司技术中心 Department of Civil and Environmental Engineering University of Illinois at Urbana-ChampaignIL 61801USA

等效力控制方法采用力反馈控制代替隐式积分方法中的迭代过程,从而使等效力控制方法在避免隐式积分方法的迭代过程的同时仍具有隐式积分方法的无条件稳定性。利用该力反馈控制,等效力控制方法还具有对实时混合试验中的时滞进行补偿的作... 详细信息

等效力控制方法采用力反馈控制代替隐式积分方法中的迭代过程,从而使等效力控制方法在避免隐式积分方法的迭代过程的同时仍具有隐式积分方法的无条件稳定性。利用该力反馈控制,等效力控制方法还具有对实时混合试验中的时滞进行补偿的作用。但是,在实际的实时混合试验中,能够影响等效力控制方法时滞补偿效果的因素有很多,测量噪声就是其中之一。本文研究了测量噪声(反馈至作动器位移命令)对等效力控制方法的影响。为了对等效力反馈中的噪声进行滤波,本文设计了Kalman滤波器。采用该Kalman滤波器,能够增加PID控制器的比例增益的取值且不损失系统的稳定性,从而提高等效力控制方法的时滞补偿效果。一系列实时混合试验表明等效力控制方法能够有效地补偿时滞。

关键词：等效力控制实时混合试验时滞补偿 Kalman滤波器磁流变阻尼器

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Emerging role of galectin 3 in neuroinflammation and neurodegeneration

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Neural Regeneration Research 2024年第9期19卷 2004-2009页

作者： brian m.Lozinski Khanh Ta Yifei Dong Department of Clinical Neuroscience University of CalgaryCalgaryABCanada Deparment of Biochemistry Microbiology&ImmunologyUniversity of SaskatchewanSaskatoonSKCanada

Neuroinflammation and neurodegeneration are key processes that mediate the development and progression of neurological ***,the mechanisms modulating these processes in different diseases remain incompletely *** in single cell based multi-omic analyses have helped to identify distinct molecular signatures such as Lgals3 that is associated with neuroinflammation and neurodegeneration in the central nervous system(CNS).Lgals3 encodes galectin-3(Gal3),aβ-galactoside and glycan binding glycoprotein that is frequently upregulated by reactive microglia/macrophages in the CNS during various neurological *** Gal3 has previously been associated with non-CNS inflammatory and fibrotic diseases,recent studies highlight Gal3 as a prominent regulator of inflammation and neuroaxonal damage in the CNS during diseases such as multiple sclerosis,Alzheimer’s disease,and Parkinson’s *** this review,we summarize the pleiotropic functions of Gal3 and discuss evidence that demonstrates its detrimental role in neuroinflammation and neurodegeneration during different neurological *** also consider the challenges of translating preclinical observations into targeting Gal3 in the human CNS.

关键词： Alzheimer’s disease Galectin 3 microglia multiple sclerosis neurodegeneration neuroinflammation Parkinson’s disease therapeutics

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Kinetics of glyphosate and aminomethylphosphonic acid sorption onto montmorillonite clays in soil and their translocation to genetically modified corn

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Journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： meichen Wang Kelly J Rivenbark Timothy D phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and aminomethylphosphonic acid(AmPA)in contaminated water,soil,sediment and plants is a cause for concern due to potential threats to the ecosystem and human health.A major route of exposure is through contact with contaminated soil and consumption of crops containing GLP and AmPA ***,clay-based sorption strategies for mixtures of GLP and AmPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AmPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(Cm)and acid processed montmorillonite(APm)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent manner without detectable *** treated with 0.5%and 1%APm inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that montmorillonite clays could be added as soil supplements to reduce hazardous mixtures of GLP and AmPA in soils and plants.

关键词： Glyphosate AmPA Adsorption Soil remediation Plant Hydroponic system

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采用Kalman滤波器的实时混合试验方法

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结构工程师 2011年第B1期27卷 52-56页

作者：史鹏飞吴斌 Billie F. Spencer, Jr. brian m. phillips Chia-ming Chang 哈尔滨工业大学土木工程学院黑龙江哈尔滨150090 美国伊利诺伊大学香槟建筑与环境工程学院伊利诺伊61801

等效力控制方法采用力反馈控制代替隐式积分方法中的迭代过程,从而使等效力控制方法在避免隐式积分方法的迭代过程的同时仍具有隐式积分方法的无条件稳定性。利用该力反馈控制,等效力控制方法还具有对实时子结构试验中的时滞进行补偿的... 详细信息

等效力控制方法采用力反馈控制代替隐式积分方法中的迭代过程,从而使等效力控制方法在避免隐式积分方法的迭代过程的同时仍具有隐式积分方法的无条件稳定性。利用该力反馈控制,等效力控制方法还具有对实时子结构试验中的时滞进行补偿的作用。但是,在实际的实时子结构试验中,能够影响等效力控制方法时滞补偿效果的因素有很多,噪声就是其中之一。本文研究了噪声对等效力控制方法稳定性的影响。提高等效力PID控制器的比例增益可对系统时滞起到补偿作用,但是当比例增益较大时,等效力反馈中的噪声会降低等效力控制方法的稳定性。为了对等效力反馈中的噪声进行滤波,本文采用了基于作动器模型设计的Kalman滤波器,并通过实时子结构实验方法对其滤波效果进行研究。研究结果表明此滤波器能够有效地过滤噪声,消除噪声对等效力控制方法稳定性的影响。

关键词：实时子结构实验等效力控制 Kalman滤波器磁流变阻尼器

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mesenchymal stem cell-based TRAIL delivery inhibits the metastatic state of clinical therapy-resistant progressive neuroblastoma

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World Journal of Pediatrics 2024年第3期20卷 287-293页

作者： Dinesh Babu Somasundaram Andrew maher Sheeja Aravindan Zhongxin Yu brian mBesch Natarajan Aravindan Department of Radiation Oncology University of Oklahoma Health Sciences CenterOklahoma CityOKUSA Stephenson Cancer Center Oklahoma CityOKUSA Department of Pathology University of Oklahoma Health Sciences CenterOklahoma CityOKUSA Radiation Biology Laboratory University of Oklahoma Health Sciences CenterBSEB 302F941 Stanton L.Young BoulevardOklahoma CityOK 73104USA

Progressive neuroblastomas(pNBs)that defy current intensive multimodal clinical therapy(ImCT)are a significant contributor to overall childhood cancer deaths[l].Neuroblastomas(NBs)that survive first-line ImCT actively evolve to acquire genetic and molecular rearrangements and display unparalleled plasticity and evolution,which causes frequent relapses in a rapidly accelerating timeline[2-4].

关键词： neuroblastoma clinical evolve

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New Opportunities for Neutrons in Environmental and Biological Sciences

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 179-186页

作者： Alexander Johs Shuo Qian Leighton Coates brian H.Davison James G.Elkins Xin Gu Jennifer morrell-Falvey Hugh O'Neill Jeffrey m.Warren Eric m.Pierce Kenneth Herwig Oak Ridge National Laboratory Oak RidgeTN37831USA

The use of neutron methods in environmental and biological sciences is rapidly emerging and accelerating with the development of new instruments at neutron user *** article,based on a workshop held at Oak Ridge National Laboratory(ORNL),offers insights into the application of neutron techniques in environmental and biological *** highlight recent advances and identify key challenges and potential future research *** include soil and rhizosphere processes,root water dynamics,plant-microbe interactions,structure and dynamics of biological systems,applications in synthetic biology and enzyme engineering,next-generation bioproducts,biomaterials and bioenergy,nanoscale structure,and fluid dynamics of porous materials in *** provide an outlook on emerging opportunities with an emphasis on new capabilities that will be enabled at the Spallation Neutron Source Second Target Station currently under design at *** mission of scientific neutron user facilities worldwide is to enable science using state-of-the-art neutron *** aim to encourage researchers in the environmental and biological research community to explore the unique capability afforded by neutrons at these facilities.

关键词： Neutrons Environment Biology Neutron imaging Neutron scattering Second Target Station(STS)

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PRELImINARY STUDY ON CHLORINE-36 DATING OF HALITE IN SALT LAKES FROm QAIDAm BASIN

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Chinese Science Bulletin 1990年第1期35卷 32-36页

作者：黄麒 Fred m.phillips Institute of Salt Lakes Academia Sinica Xining 810008 PRC New mexico Institute of mining and Technology USA

The Qaidam Basin is a large intermontane depression. It has been in existence since the Jurassic. The mean elevation of the basin floor is 2800 m. It covers an area of 120,000 km^2 with a catchment area of about 250,000 km^2. By the end of the Pliocene, great changes had taken place. Some of the lakes were evolving to the evaporite formation stage. The deposition continued through the Pliocene and the late Pleistocene to produce a sequence 2000—3000 m thick, and the total thickness of halite sequence is more than 1000 m. The Qaidam Basin contains some of the richest salt resources, the sediments deposited on

关键词： salt lake halite chlorine-36 dating.

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Advancements in endoscopic hemostasis for non-variceal upper gastrointestinal bleeding

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World Journal of Gastrointestinal Endoscopy 2024年第7期16卷 376-384页

作者： Xue Jing Li brian m Fung Department of Gastroenterology and Hepatology Banner-University Medical Center PhoenixPhoenixAZ 85006United States

Non-variceal upper gastrointestinal(GI)bleeding is a significant cause of morbidity and ***,through-the-scope(TTS)clips,thermal therapy,and injection therapies are used to treat GI *** this review,we provide an overview of novel endoscopic treatments that can be used to achieve ***,we discuss the efficacy and applicability of over-thescope clips,hemostatic agents,TTS doppler ultrasound,and endoscopic ultrasound,each of which offer an effective method of reducing rates of GI rebleeding.

关键词： Doppler probe Endoscopic ultrasound Endoscopy techniques Gastrointestinal bleeding Hemospray Hemostasis Hemostatic agents Over-the-scope clips Ovesco

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EVOLUTIONARY CHARACTERISTICS OF LAKES AND PALAEOCLImATIC UNDULATION IN THE Q AID Am BASIN,CHINA

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Chinese Journal of Oceanology and Limnology 1993年第1期11卷 34-45页

作者：黄麒 Teh-Lung Ku Fred m.phillips Institute of Salt Lakes Academia Sinica Xining 810008 Department of Geological Sciences University of Southern California Los Angeles CA. 90089-0740 U.S.A. Geoscience Department New Mexico Institute of Mining and Technology Socorro NM 87801 U.S.A

The Qaidam Basin is. a tectonically controlled depression at 2700 m altitude on the northern margin of the Tibet Plateau. A succession of Neogene clastic sediments indicates lake depocentre migration from NW to SE. Towards late Pliocene, evaporative conditions developed with formation of gypsum, halite, celestite, mirabilite and bloedite. Continued deformation through Pleistocene developed a series of NW- SE trending domes and troughs. This setting continued to exert a controlling influence on basin and brine evolution and the progressive development of sulfate to chloride brines as, dry conditions intensified in late Pleistocene, at the end of which, extensive flat floors were formed in Dalangtan, Qarhan and other ***, model, which was set up based on the synthetic analyses, divides the fluctuating palaeoclimate since 750ka,B. P. into 11 warm and humid stages and 10 dry and cold stages. The water of the lakes evaporated during the dry-cold periods and were freshened during the warm-humid

关键词： evolution of salt lakes organic carbon stratigraphy undulating model of paleoclimate

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