检索结果-南通市图书馆

Can incidental sighting data be used to elucidate habitat preferences and areas of suitable habitat for a cryptic species?

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2017年第3期12卷 186-197页

作者： wesley R.HAUSER Sigrid R.HEISE-PAVLOV Indiana University School of Public and Environmental AffairsBloomingtonIndianaUSA Centre for Rainforest Studies School for Field StudiesYungaburraQueenslandAustralia

The involvement of communities in ecological studies has been shown to augment conservation efforts,especially for cryptic ***,there is a lack of studies addressing the utility of incidental sighting records from community members in gaining knowledge on habitat preferences and distribution of suitable habitat for these *** study compares preferences of the Lumholtz’s tree kangaroo(Dendrolagus lumholtzi;LTK),a cryptic rainforest folivore in northeastern Australia,for various habitat and climatic variables derived from data collected during scientific projects to those derived from incidental sighting records using ArcGIS and *** sighting records suggest that the species uses a wider range of altitudes,annual rainfalls,annual mean temperatures and vegetation types than predicted by scientific *** records also show that the species can persist in areas of lower rainfall during the wettest month and lower minimum temperature during the coldest *** data place the species within a comparable range of rainfalls during the driest month,maximum temperatures of the warmest month and soil *** using identified preferences to assess the extent and distribution of suitable habitat,incidental records predicted more areas of suitable habitat than scientific records with an overlap of up to 91%between *** present study proves that incidental sighting records can be a valuable part of the study of cryptic species and should be considered complementarily alongside scientific studies to obtain comprehensive ecological information of a species that can assist in its conservation.

关键词： cryptic species Dendrolagus lumholtzi incidental sighting data habitat preferences Lumholtz’s tree kangaroo

Time's up:mutation rate and lifespan

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第9期7卷 3166-3167页

作者： Anjali Cremer wesley T.Abplanalp Michael A.Rieger Department of Medicine Hematology/OncologyGoethe University FrankfurtFrankfurt am MainGermany Frankfurt Cancer Institute Frankfurt am MainGermany German Cancer Consortium(DKTK)and German Cancer Research Center(DKTK) HeidelbergGermany Institute for Cardiovascular Regeneration Centre of Molecular MedicineGoethe University FrankfurtFrankfurt am MainGermany German Center for Cardiovascular Research DZHK Partner site Frankfurt Rhine-MainBerlinGermany Cardiopulmonary Institute Goethe University FrankfurtFrankfurtGermany EnABLE Consortium Goethe University FrankfurtFrankfurtGermany

In a recent study published in Nature,Alex Cagan,Adrian Baez-Ortega and colleagues found that many mammalian species present a similar somatic mutational load at the end of *** mutational burden is independent of lifetime and body mass,only varying by a relatively small fold change among species.1These data may suggest that mutational burden predicts mortality.

关键词： species. life lifetime

Investigation on Adipose Mechanical Properties under Compression Loading for Improving Human Body Modelling

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Investigation on Adipose Mechanical Properties under Compres...

作者： wesley Chebii Rutto 湖南大学

学位级别：硕士

迄今为止,旨在减轻弹道和弹片攻击的军事级装甲材料在抵抗爆炸冲击方面效果较差。为了改善装甲的爆炸吸收特性,第一步是彻底了解爆炸对人体本身的影响。皮下脂肪组织与人体其他软组织一样,容易受到爆炸冲击和弹片穿透等影响。但是,目前... 详细信息

迄今为止,旨在减轻弹道和弹片攻击的军事级装甲材料在抵抗爆炸冲击方面效果较差。为了改善装甲的爆炸吸收特性,第一步是彻底了解爆炸对人体本身的影响。皮下脂肪组织与人体其他软组织一样,容易受到爆炸冲击和弹片穿透等影响。但是,目前尚缺乏表征脂肪对变化负荷条件的生物力学响应的研究。这为研究脂肪组织负荷的机理提供了充分的依据,这将是改善保护装置设计的关键一步。基于改进PPE的需要,当前的研究工作旨在通过研究在不同应变率下的准静态和动态压缩载荷下的力学性能,来研究脂肪组织的力学。主要目的是通过实验测试和数值模拟来了解组织的应变率响应,并确定最能预测皮下组织AT载荷-变形行为的模型。获得脂肪组织的力学特性,并与现有脂肪组织相结合,为今后生物力学领域的建模提供参考。取猪皮下脂肪组织作为标本。利用MTS万能试验机对试件进行单轴压缩试验,获得应力应变响应数据。试件被切割成10×10×10mm的立方体。分别在0.05%/s、0.5%/s和5%/s三个应变速率范围内进行了试验。选择三阶QLV和一阶Ogden的材料本构模型对皮下脂肪组织的被动行为进行建模。用python代码对实验数据进行数值模拟。超弹性的材料参数;α=8.41μ=16.4,C=-136.980,C=-225.60,C=3636.85。设计了一个有限元模型来模拟脂肪组织。为了得到准确的结果,对它进行了精细的网格划分。0.05%～5%应变率的平均弹性模量和剪切模量为:初始E≈12.71±10.93 k Pa,最终E≈1300±66.60 k Pa。初始刚度模量G≈4.23±2.30 k Pa,最终G≈433.30±22.20 k PaOgden和拟线性粘弹性模型的相关系数R=0.9809,R=0.9986。这些是模型与实验数据在0.5%应变率下的确定系数。实验和仿真结果的比较表明,该模型能够较准确地再现应力应变曲线。因此,所建议的材料参数能够较好地预测皮下脂肪组织的负荷和变形。皮下脂肪组织具有应变速率依赖性,在稳态载荷下表现出非线性的应力-应变响应。它在准静态载荷作用下表现出柔软、顺从的特性,在动态载荷作用下表现出刚性、回弹性的特性。

关键词：皮下脂肪组织应变率有限变形粘弹性单轴压缩

Cloud computing for integrated stochastic groundwater uncertainty analysis

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2013年第4期6卷 313-337页

作者： Yong Liu Alexander Y.Sun Keith Nelson wesley E.Hipke National Center for Supercomputing Applications University of Illinois at Urbana-ChampaignUrbanaILUSA Bureau of Economic Geology University of Texas at AustinAustinTXUSA Arizona Department of Water Resources PhoenixAZUSA

One of the major scientific challenges and societal concerns is to make informed decisions to ensure sustainable groundwater availability when facing deep uncertainties.A major computational requirement associated with this is on-demand computing for risk analysis to support timely *** paper presents a scientific modeling service called‘ModflowOnAzure’which enables large-scale ensemble runs of groundwater flow models to be easily executed in parallel in the Windows Azure *** technical issues were addressed,including the conjunctive use of desktop tools in MATLAB to avoid license issues in the cloud,integration of Dropbox with Azure for improved usability and‘Drop-and-Compute,’and automated file exchanges between desktop and the *** scientific use cases are presented in this paper using this service with significant computational *** case is from Arizona,where six plausible alternative conceptual models and a streamflow stochastic model are used to evaluate the impacts of different groundwater pumping *** case is from Texas,where a global sensitivity analysis is performed on a regional groundwater availability *** of both cases show informed uncertainty analysis results that can be used to assist the groundwater planning and sustainability study.

关键词： MODFLOW groundwatersustainability uncertaintyanalysis global sensitivity analysis cloudcomputing WindowsAzure Dropbox alternative conceptual model cyberinfrastructure eScience

A Case Report of Methylobacterium radiotolerans Bacteremia and Brain Abscesses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Microbes & Diseases 2021年第2期3卷 112-114页

作者： wesley Tang Alpa Desai Kunal Desai Department of Medicine Kettering Medical CenterKetteringOhioUSA Department of Internal Medicine Boonshoft School of MedicineWright State UniversityDaytonOhioUSA Kettering Health Network KetteringOhioUSA.

Methylobacterium radiotolerans is a ubiquitous organism found in the environment and is considered an opportunistic pathogen of low virulence in *** human infections from *** have been reported in immunocompromised hosts and have been reported mainly as bloodstream infections related to central venous *** present the first known case of *** as a causative agent of multiple brain abscesses in an immunocompromised host.

关键词： brain abscesses immunocompromise Methylobacterium opportunistic infections

Mechanical testing of two-dimensional materials:a brief review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Smart and Nano Materials 2020年第3期11卷 207-246页

作者： Karrar K.Al-Quraishi Qing He wesley Kauppila Min Wang Yingchao Yang Department of Mechanical Engineering University of MaineOronoMEUSA Department of Mechanical Engineering Quzhou UniversityQuzhouZhejiangChina Department of Mechanical Engineering University of MaineOronoME 04469USA

Two-dimensional(2D)materials have dominated nanoscience for the last two *** all 2D materials,graphene,MoS_(2),and h-BN are extremely popular and have been tenta-tively scaled up to fabricate nanocomposites,energy storage devices,flexible electronics,etc.,ex situ and in situ mechanical characterization of 2D crystals can help us understand their mechanical behavior and measure their mechanical properties,which are of great significance in both fundamental science and practical *** date,a great effort has been devoted to both theoretical and experimental mechanics with a focus on unveiling mechanical behaviors and quantifying mechanical *** original research,several insightful review works have been published with a specific focus on the mechanics of 2D *** have a complementary contribu-tion to the overview of the mechanics of 2D materials,we would like to review the developed experimental techniques being used to mechanically characterize 2D *** work-ing mechanism and associated advantages and disadvantages of the techniques will be briefly *** on the exis-tence of arguments in mechanical properties and behaviors of 2D crystals,and immature mechanical characterization of 2D materials,more intensive and comprehensive studies are expected toward a full understanding of these novel and pro-mising materials.

关键词： 2D materials mechanical property mechanical behavior

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Agricultural Science and Engineering 2017年第3期4卷 260-267页

作者： Ying HUANG Clement wesley GNANADURAI Zhenfang FU Department of Pathology College of Veterinary MedicineUniversity of Georgia State Key Laboratory of Agricultural Microbiology College of Veterinary MedicineHuazhong Agricultural University

The innate immune response is the first line of defense against viral invasion and pro-inflammatory chemokines and cytokines have a critical function in the innate immune responses against virus infections. The ability of a rabies virus(RABV) to induce the expression of chemokines and cytokines can lead to viral clearance from the central nervous system(CNS), whereas the ability to evade such expression and activation contributes to virulence and pathogenicity. In this review, the crucial contribution of chemokines/cytokines to clearing RABV from the CNS is discussed, including recruiting leukocytes into the CNS, enhancement of blood brain barrier permeability and activation of various immune cells that are essential for viral clearance. In addition, recombinant RABV expressing cytokines and chemokines can induce elevated innate and adaptive immune responses which result in clearing an established wild-type RABV infection in the CNS.

关键词： antiviral blood brain barrier chemokines and cytokines innate immunity rabies virus

Effect of 5-FU on modulation of disarrangement of immune-associated cytokines in experimental acute pancreatitis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第16期15卷 2032-2037页

作者： Xiao-Li Chen Sang-Zhu Ciren Hui Zhang Li-Geng Duan Alexander J wesley Department of General Surgery The Huaxi Hospital Medical Center University of Sichuan Chengdu 610041 China Department of Surgery Transplantation Division University of Cincinnati Medical Center Cincinnati OH 45267-0558 United States

AIM： To investigate the effects of 5-Fluorouracil （5-FU） on modulation of pro-inflammatory and anti-inflammatory cytokines in acute pancreatitis and the mechanism of it in the treatment of acute pancreatitis. METHODS： Male Sprague Dawley rats were assigned to 3 Groups： Group A, sham operated rats as controls （n = 7）; Group B, acute pancreatitis induced by ductal injection with 5% sodium cholate at a volume of 1.0 mL/kg without any other treatment; Group C, after the pancreatitis was induced as in Group B, the rats were injected intravenously with 5-FU 40 mg/kg. The animals in Groups B and C were killed at 2, 6 and 24 h after operation （n = 7）, and blood samples were taken for measurement of tumor necrosis factor-α （TNF-α）, interleukin-1 （IL-1）, interleukin-6 （IL-6）（by bioassay）, and interleukin-10 （IL-10）, transforming growth factor-β （TGF-β）（by ELISA）. The wet weight of pancreatic tissue, serum amylase levels and white blood cells were also measured. RESULTS： Four rats in Group B and one in Group C died after pancreatitis was induced. Both pro-inflammatory cytokines （TNF-α, IL-1, IL-6） at the 2 and 6 h period and the anti-inflammatory cytokines （IL-10, TGF-β） at 24 h increased significantly （P 〈 0.05） in rats of Group B. After treatment with 5-FU, TNF-α, IL-1, and IL-6 in serum of rats of Group C were inhibited at 2 and 6 h after operation （P 〈 0.05）, and IL-IO, TGF-13 were inhibited at 24 h compared to Group B （P 〈 0.05）. Obvious improvements in the severity of the acute pancreatitis, including the amylase levels, wet weight of pancreatic tissue and neutrophil counts, were also observed after treatment with 5-FU. CONCLUSION： 5-FU is an anti-metabolic and immunosuppressive agent which can minimize the abnormal immune o/tokine response and relieve the pathophysiological disorders associated with experimental acute pancreatitis.

关键词： Pancreatitis Cytokines Systemic inflammatory response syndrome 5-Fluorouracil

Linear synchronization and circuit implementation of chaotic system with complete amplitude control

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2017年第12期26卷 124-133页

作者：李春彪 wesley Joo-Chen Thio Julien Clinton Sprott 张若洵陆天爱 Jiangsu Key Laboratory of Meteorological Observation and Information Processing Nanjing University of Information Science & Technology Nanjing 210044 China School of Electronic & Information Engineering Nanjing University of Information Science & Technology Nanjing 210044 China Department of Electrical and Computer Engineering The Ohio State University Columbus OH 43210 USA Department of Physics University of Wisconsin-Madison Madison WI 53706 USA College of Teacher Education Xingtai University Xingtai 054001 China

Although chaotic signals are considered to have great potential applications in radar and communication engineering, their broadband spectrum makes it difficult to design an applicable amplifier or an attenuator for amplitude conditioning. Moreover, the transformation between a unipolar signal and a bipolar signal is often required. In this paper, a more intelligent hardware implementation based on field programmable analog array （FPAA） is constructed for chaotic systems with complete amplitude control. Firstly, two chaotic systems with complete amplitude control are introduced, one of which has the property of offset boosting with total amplitude control, while the other has offset boosting and a parameter for partial control. Both cases can achieve complete amplitude control including amplitude rescaling and offset boosting. Secondly, linear synchronization is established based on the special structure of chaotic system. Finally, experimental circuits are constructed on an FPAA where the predicted amplitude control is realized through only two independent configurable analog module （CAM） gain values.

关键词： complete amplitude control amplitude rescaling offset boosting linear synchronization