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Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases:A systematic review and meta-analysis

World Journal of Gastroenterology 2024年第7期30卷 742-758页

作者： Eyad Gadour Abeer Awad Zeinab Hassan Khalid Jebril Shrwani bogdan miutescu Hussein Hassan Okasha Department of Gastroenterology and Hepatology King Abdulaziz Hospital-National GuardAhsa 31982Saudi Arabia Department of Internal Medicine Faculty of MedicineZamzam University CollegeKhartoum 11113Sudan Department of Hepatogastroenterology Kasar Alainy HospitalFaculty of MedicineCairo UniversityCairo 11451Egypt Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Public Health Authority Saudi Center for Disease Prevention and ControlJazan 45142Saudi Arabia Department of Clinical Infection Microbiology and ImmunologyInstitute of Infection and Global HealthSchool of Medicine and Life SciencesUniversity of LiverpoolLiverpoolUnited Kingdom Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Center in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 30041Romania Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt

BACKGROUND In hepatology,the clinical use of endoscopic ultrasound(EUS)has experienced a notable increase in recent *** applications range from the diagnosis to the treatment of various liver ***,this systematic review summarizes the evidence for the diagnostic and therapeutic roles of EUS in liver *** To examine and summarize the current available evidence of the possible roles of the EUS in making a suitable diagnosis in liver diseases as well as the therapeutic accuracy and *** PubMed,Medline,Cochrane Library,Web of Science,and Google Scholar databases were extensively searched until October *** methodological quality of the eligible articles was assessed using the Newcastle-Ottawa scale or Cochrane Risk of Bias *** addition,statistical analyses were performed using the Comprehensive Meta-Analysis *** Overall,45 articles on EUS were included(28 on diagnostic role and 17 on therapeutic role).Pooled analysis demonstrated that EUS diagnostic tests had an accuracy of 92.4%for focal liver lesions(FLL)and 96.6%for parenchymal liver ***-guided liver biopsies with either fine needle aspiration or fine needle biopsy had low complication rates when sampling FLL and parenchymal liver diseases(3.1%and 8.7%,respectively).Analysis of data from four studies showed that EUS-guided liver abscess had high clinical(90.7%)and technical success(90.7%)without significant ***,EUS-guided interventions for the treatment of gastric varices(GV)have high technical success(98%)and GV obliteration rate(84%)with few complications(15%)and rebleeding events(17%).CONCLUSION EUS in liver diseases is a promising technique with the potential to be considered a first-line therapeutic and diagnostic option in selected cases.

关键词： Focal liver lesion Liver abscess drainage Fine needle aspiration Gastric varices Endoscopic ultrasound

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Linear endoscopic ultrasound:Current uses and future perspectives in mediastinal examination

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World Journal of Gastroenterology 2024年第33期30卷 3803-3809页

作者： Eyad Gadour Sarah Al Ghamdi bogdan miutescu Hossam E Shaaban Zeinab Hassan Aymen Almuhaidb Hussein H Okasha Department of Gastroenterology and Hepatology King Abdulaziz National Guard HospitalAhsa 36428Saudi Arabia Department of Internal Medicine Zamzam University CollegeSchool of MedicineKhartoum 11113Sudan Department of Medicine Division of GastroenterologyKing Abdulaziz UniversityJeddah 3646Saudi Arabia Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Center in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Department of Internal Medicine and Gastroenterology NhtmriCairo 11796Egypt Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Department of Gastroenterology King Faisal Specialist Hospital and Research CenterRiyadh 11211Saudi Arabia Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt

This editorial elaborates on the current and future applications of linear endoscopic ultrasound(EUS),a substantial diagnostic and therapeutic modality for various anatomical *** scope of endosonographic assessment is broad and,among other factors,allows for the evaluation of the mediastinal anatomy and related pathologies,such as mediastinal lymphadenopathy and the staging of central malignant lung ***,EUS assessment has proven more accurate in detecting small lesions missed by standard imaging examinations,such as computed tomography or magnetic resonance *** focus on its current uses in the mediastinum,including lung and esophageal cancer staging,as well as evaluating mediastinal lymphadenopathy and submucosal *** editorial also explores future perspectives of EUS in mediastinal examination,including ultrasound-guided therapies,artificial intelligence integration,advancements in mediastinal modalities,and improved diagnostic approaches for various mediastinal lesions.

关键词： Linear endoscopic ultrasound Mediastinal examination Lung cancer Computed tomography Magnetic resonance imaging

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Practical approach to linear endoscopic ultrasound examination of the gallbladder

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World Journal of Radiology 2024年第6期16卷 184-195页

作者： Hussein Hassan Okasha Eyad Gadour Hassan Atalla Omar AbdAllah AbdEl-Hameed Reem Ezzat Ahmed Elsayed Alzamzamy Elsayed Ghoneem Rasha Ahmad Matar Zeinab Hassan bogdan miutescu Ayman Qawasmi Katarzyna M Pawlak Ahmed Elmeligui Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt Department of Gastroenterology and Hepatology King Abdulaziz Hospital-National GuardAhsa 31982Saudi Arabia Department of Medicine School of MedicineZamzam University CollegeKhartoum 11113Sudan Department of Internal Medicine Hepatology and Gastroenterology UnitFaculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Internal Medicine Faculty of MedicineAssiut UniversityAssiut 71511Egypt Department of Gastroenterology and Heptology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11728Egypt Department of Gastroenterology and Advance Endoscopy Sultant Qaboos Comprehensive Cancer Care and Research CentreMuscat 0961Oman Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Centre in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 30041Romania Department of Gastroenterology Al-Makassed Islamic Charitable Society HospitalCairo 11124Egypt Division of Gastroenterology St.Michael’s HospitalUniversity of TorontoToronto M5B 1W8Canada Department of Gastroenterology Southend University HospitalEssex SS26XTUnited Kingdom

The gallbladder(GB)is a susceptible organ,prone to various pathologies that can be identified using different imaging *** ultrasound(TUS)is typically the initial diagnostic method due to its numerous well-established ***,in cases of uncertainty or when a definitive diagnosis cannot be established,computed tomography(CT)or magnetic resonance imaging may be employed to provide more detailed ***,CT scans may sometimes offer inadequate spatial resolution,which can limit the differentiation of GB lesions,particularly when smaller yet clinically relevant abnormalities are ***,endoscopic ultrasound(EUS)provides higher frequency compared to TUS,superior spatial resolution,and the option for contrast-enhanced harmonic imaging,enabling a more comprehensive ***,EUS can serve as a supplementary tool when conventional imaging methods are *** review will describe the standard EUS examination of the GB,focusing on its endosonographic characteristics in various GB path-ologies.

关键词： Endoscopic ultrasound Linear endoscopic ultrasound Gallbladder anatomy Gallbladder pathologies Therapeutic endoscopic ultrasound

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Bridging element-free Galerkin and pluri-Gaussian simulation for geological uncertainty estimation in an ensemble smoother data assimilation framework

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Petroleum Science 2024年第3期21卷 1683-1698页

作者： bogdan Sebacher Remus Hanea Department of Applied Informatics Military Technical Academy“Ferdinand I”Bucharest 050141Romania Equinor Sandslivegen 905254 SandsliBergenNorway

The facies distribution of a reservoir is one of the biggest concerns for geologists,geophysicists,reservoir modelers,and reservoir engineers due to its high importance in the setting of any reliable decisionmaking/optimization of field development *** approach for parameterizing the facies distribution as a random variable comes naturally through using the probability *** the prior probability fields of facies come either from a seismic inversion or from other sources of geologic information,they are not conditioned to the data observed from the cores extracted from the *** paper presents a regularized element-free Galerkin(R-EFG)method for conditioning facies probability fields to facies *** conditioned probability fields respect all the conditions of the probability theory(*** the values are between 0 and 1,and the sum of all fields is a uniform field of 1).This property achieves by an optimization procedure under equality and inequality constraints with the gradient projection *** conditioned probability fields are further used as the input in the adaptive pluri-Gaussian simulation(APS)methodology and coupled with the ensemble smoother with multiple data assimilation(ES-MDA)for estimation and uncertainty quantification of the facies *** history-matching of the facies models shows a good estimation and uncertainty quantification of facies distribution,a good data match and prediction capabilities.

关键词： Element free Galerkin(EFG) Adaptive pluri-Gaussian simulation(APS) Facies distribution estimation Ensemble smoother with multipledata assimilation(ESMDA)

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Disaster Awareness and Preparedness Among Older Adults in Canada Regarding Floods, Wildfires, and Earthquakes

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International Journal of Disaster Risk Science 2024年第2期15卷 198-212页

作者： Evalyna bogdan Rachel Krueger Julie Wright Kyle Woods Shaieree Cottar School of Administrative Studies Disaster and Emergency Management ProgramYork UniversityTorontoOntario M3J 1P3Canada Department of Geography and Environmental Management University of WaterlooWaterlooOntario N2L 3G1Canada Partners for Action Faculty of EnvironmentUniversity of WaterlooWaterlooOntario N2L 3G1Canada

Older adults are significantly impacted by natural hazards and disasters that are exacerbated by climate change. Understanding their awareness and preparedness is essential for enhancing disaster resilience. This study investigated the attitudes, actions, and recommendations of older adults regarding natural hazards that pose risks in their geographic area—specifically floods, wildfires, and/or earthquakes in Canada. Methods for this study included survey and focus groups with older adults(n = 161 and n = 10, respectively) and other high-risk groups from across Canada, that are vulnerable to these natural hazards. The main findings from this study are that current awareness and preparedness among older adults is low, though stronger perceptions of risks are associated with risks specific to geographic locations where respondents live. Several barriers, such as hazard vulnerability misperceptions, cost-related reasons, and lack of hazard awareness have resulted in low awareness and preparedness among these populations. The two main recommendations arising from this research are:(1) improve awareness and preparedness with tailor-made emergency preparedness materials for older adults;and(2) adopt community-based approaches to disaster preparedness through existing community groups to strengthen social connections with a focus on locally specific hazards. The findings from this research can be applied to other hazards, including heatwaves and pandemics.

关键词： Canada Community-based disaster risk management Disaster awareness and preparedness Disaster resilience Natural hazards Older adults

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High Impact Polylactide Based on Organosilicon Nucleation Agent

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Chinese Journal of Polymer Science 2024年第6期42卷 787-797页

作者： Daria Pakuła Bogna Sztorch Eliza Romańczuk-Ruszuk bogdan Marciniec Robert E.Przekop Faculty of Chemistry Adam Mickiewicz University in PoznańUniwersytetu Poznańskiego 861-614PoznańPoland Centre for Advanced Technologies Adam Mickiewicz University in PoznańUniwersytetu Poznańskiego 1061-614PoznańPoland Institute of Biomedical Engineering Faculty of Mechanical EngineeringBialystok University of TechnologyWiejska 45C15-351BialystokPoland

Various sectors of the industry are searching for new materials with specific requirements,providing improved *** study presents novel composite materials based on polylactide that have been modified with the organosilicon compound,(3-thiopropyl)polysilsesquioxane(SSQ-SH).The SSQ-SH compound is a mixture of cage structures and not fully condensed random *** composite materials were obtained through injection *** study includes a comprehensive characterization of the new materials that analyze their functional properties,such as rheology(MFR),mechanical strength(tensile strength,Charpy impact strength),and thermal *** microscopic photos were also taken to analyze the microstructure of the *** addition of a 5%by-weight organosilicon compound to polylactide resulted in a significant increase in MFR by 73.8%compared to the neat *** greatest improvement in impact strength was achieved for the 5%SSQ-SH/PLA composite,increasing it by 32.0 kJ/m^(2)compared to PLA,which represents an increase of up to 187%.The conducted research confirms the possibility of modifying the properties of the polymer by employing organosilicon compounds.

关键词： Octa(3-thiopropyl)silsesquioxane 8SH-POSS Polylactide(PLA) Injection moulding Composites

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High-speed performance self-powered short wave ultraviolet radiation detectors based onκ(ε)-Ga_(2)O_(3)

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Journal of Semiconductors 2024年第4期45卷 56-62页

作者： Aleksei Almaev Alexander Tsymbalov bogdan Kushnarev Vladimir Nikolaev Alexei Pechnikov Mikhail Scheglov Andrei Chikiryaka Petr Korusenko Research and Development Center for Advanced Technologies in Microelectronics National Research Tomsk State UniversityTomsk 634050Russia Fokon LLC Kaluga 248035Russia Department of Semiconductor Electronics and Physics of Semiconductors National University of Science and Technology MISISMoscow 119049Russia Perfect Crystals LLC Saint Petersburg 194223Russia Department of Solid-State Electronics Saint Petersburg State UniversitySaint Petersburg 199034Russia Department of Physics Omsk State Technical UniversityOmsk 644050Russia

High-speed solar-blind short wavelength ultraviolet radiation detectors based onκ(ε)-Ga_(2)O_(3)layers with Pt contacts were demonstrated and their properties were studied in ***κ(ε)-Ga_(2)O_(3)layers were deposited by the halide vapor phase epitaxy on patterned GaN templates with sapphire *** spectral dependencies of the photoelectric properties of struc-tures were analyzed in the wavelength interval 200-370 *** maximum photo to dark current ratio,responsivity,detectiv-ity and external quantum efficiency of structures were determined as:180.86 ***.,3.57 A/W,1.78×10^(12) Hz^(0.5)∙cm·W^(-1) and 2193.6%,respectively,at a wavelength of 200 nm and an applied voltage of 1 *** enhancement of the photoresponse was caused by the decrease in the Schottky barrier at the Pt/κ(ε)-Ga_(2)O_(3)interface under ultraviolet *** detectors demon-strated could functionalize in self-powered mode due to built-in electric field at the Pt/κ(ε)-Ga_(2)O_(3)*** responsivity and external quantum efficiency of the structures at a wavelength of 254 nm and zero applied voltage were 0.9 mA/W and 0.46%,*** rise and decay times in self-powered mode did not exceed 100 ms.

关键词： κ(ε)-gallium oxide solar-blind shortwave ultraviolet radiation detectors self-powered operation mode

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Self-powered UVC detectors based on α-Ga_(2)O_(3) with enchanted speed performance

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Journal of Semiconductors 2024年第8期45卷 74-80页

作者： Aleksei Almaev Alexander Tsymbalov bogdan Kushnarev Vladimir Nikolaev Alexei Pechnikov Mikhail Scheglov Andrei Chikiryaka Laboratory of Metal Oxide Semiconductors Research and Development Center for Advanced Technologies in MicroelectronicsNational Research Tomsk State UniversityTomsk 634050Russia Fokon LLC Kaluga 248035Russia Department of Semiconductor Electronics and Physics of Semiconductors National University of Science and Technology MISISMoscow 119049Russia Perfect Crystals LLC Saint Petersburg 194223Russia

Detectors were developed for detecting irradiation in the short-wavelength ultraviolet(UVC)interval using high-quality single-crystallineα-Ga_(2)O_(3) films with Pt interdigital *** films ofα-Ga_(2)O_(3) were grown on planar sapphire substrates with c-plane orientation using halide vapor phase *** spectral dependencies of the photo to dark current ratio,responsivity,external quantum efficiency and detectivity of the structures were investigated in the wavelength interval of 200−370 *** maximum of photo to dark current ratio,responsivity,external quantum efficiency,and detectivity of the structures were 1.16×10^(4) ***.,30.6 A/W,1.65×10^(4)%,and 6.95×10^(15) Hz^(0.5)·cm/W at a wavelength of 230 nm and an applied voltage of 1 *** high values of photoelectric properties were due to the internal enhancement of the photoresponse associated with strong hole ***α-Ga_(2)O_(3) film-based UVC detectors can function in self-powered operation mode due to the built-in electric field at the Pt/α-Ga_(2)O_(3) *** a wavelength of 254 nm and zero applied voltage,the structures exhibit a responsivity of 0.13 mA/W and an external quantum efficiency of 6.2×10^(−2)%.The UVC detectors based on theα-Ga_(2)O_(3) films demonstrate high-speed performance with a rise time of 18 ms in self-powered mode.

关键词： HVPE gallium oxide solar-blind ultraviolet detector self-powered mode

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Photoluminescence,structural and antibacterial properties of co-dopedβ-Ca_(3)(PO_(4))_(2)-type phosphates Ca_(8)CuRE(PO_(4))_(7)(RE=Eu-Er)

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Journal of Rare Earths 2024年第9期42卷 1658-1668,I0002页

作者： Ivan V.Nikiforov Ekaterina V.Iliin bogdan I.Lazoryak Sergey M.Aksenov Pavel V.Slukin Dina V.Deyneko Department of Chemistry Lomonosov Moscow State University119991MoscowRussia Laboratory of Arctic Mineralogy and Material Sciences Kola Science CentreRussian Academy of Sciences184209ApatityRussia Geological Institute Kola Science CentreRussian Academy of Sciences184209ApatityRussia State Scientific Center of Applied Microbiology and Biotechnology of Rospotrebnadzor 24 Block A142279ObolenskRussia

Novel Ca_(8)CuRE(PO_(4))_(7)where RE^(3+)=Eu^(3+),Tb^(3+),Dy^(3+),Ho^(3+)and Er^(3+)were synthesized by a solid-state method in *** structures of the samples were characterized by powder X-ray diffraction using Rietveld refinement to determine the occupation of crystal *** samples are found to have a centrosymmetric structure with space group R3c,as shown by dielectric *** synthesized Ca_(8)CuRE(PO_(4))_(7)samples have multifunctional *** Cu^(2+)ions provide antibacterial properties,while the rare earth elements ions exhibit luminescence properties,and theβ-Ca_3(PO_(4))_(2)-type host is *** photoluminescence properties of RE^(3+)ions were studied and compared with other simmilar Ca_(8)MRE(PO_(4))_(7)phosphates,where M is a divalent *** photoluminescence intensity quenching in terms of energy transfer from RE^(3+)to Cu^(2+)is *** bioactive properties were studied in relation to antibacterial activity against *** and *** syntesized Ca_(8)CuRE(PO_(4))_(7)samples demonstrate very high and stable inhibition of bacteria *** correlation between crystal structure and properties is *** combining multiple approaches to the directio nal design of such materials,several important properties within a single chemical compound to achieve biovisualization and bioactive properties simultaneously can be combined.

关键词： β-Ca_(3)(PO_(4))_(2) Whitlockite-type structure Bioactive phosphates TCP Photoluminescence Rare earths

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Competitive effect, but not competitive response, varies along a climatic gradient depending on tree species identity

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Forest Ecosystems 2024年第2期11卷 142-151页

作者： Teresa Valor Lluís Coll David I.Forrester Hans Pretzsch Miren del Río Kamil Bielak bogdan Brzeziecki Franz Binder Torben Hilmers Zuzana Sitková Roberto Tognetti Aitor Ameztegui Department of Agricultural and Forest Sciences and Engineering(DCEFA) University of LleidaAv.Alcalde Rovira Roure 191E25198 LleidaSpain Joint Research Unit CTFC-AGROTECNIO-CERCA Ctra.Sant LlorençKm.225280SolsonaSpain Swiss Federal Institute of Forest Snow and Landscape Research WSLZürcherstrasse 1118903BirmensdorfSwitzerland CSIRO Land and Water GPO Box 1700CanberraACT2601Australia Chair of Forest Growth and Yield Science School of Life Sciences WeihenstephanTechnical University of MunichHans-Carl-Von-Carlowitz-Platz 285354FreisingGermany Forest Research Center INIA-CSICCtra.A Coruña Km 7.528040MadridSpain IuFOR Sustainable Forest Management Research InstituteUniversity of Valladolid&INIASpain Department of Silviculture Institute of Forest SciencesWarsaw University of Life SciencesNowoursynowska 159/3402776WarsawPoland Bavarian State Institute of Forestry(LWF) Hans-Carl-von-Carlowitz-Platz 1D-85354FreisingGermany National Forest Centre Forest Research InstituteT.G.Masaryka 2296001ZvolenSlovakia Faculty of Agricultural Environmental and Food SciencesFree University of Bozen-Bolzano Piazza Università1 I-39100Bolzano

Background: Understanding the role of species identity in interactions among individuals is crucial for assessing the productivity and stability of mixed forests over time. However, there is limited knowledge concerning the variation in competitive effect and response of different species along climatic gradients. In this study, we investigated the importance of climate, tree size, and competition on the growth of three tree species: spruce(Picea abies), fir(Abies alba), and beech(Fagus sylvatica), and examined their competitive response and effect along a climatic ***: We selected 39 plots distributed across the European mountains with records of the position and growth of 5,759 individuals. For each target species, models relating tree growth to tree size, climate and competition were proposed. Competition was modelled using a neighbourhood competition index that considered the effects of inter-and intraspecific competition on target trees. Competitive responses and effects were related to *** methods and information theory were used to select the best ***: Our findings revealed that competition had a greater impact on target species growth than tree size or climate. Climate did influence the competitive effects of neighbouring species, but it did not affect the target species? response to competition. The strength of competitive effects varied along the gradient, contingent on the identity of the interacting species. When the target species exhibited an intermediate competitive effect relative to neighbouring species, both higher inter-than intraspecific competitive effects and competition reduction occurred along the gradient. Notably, species competitive effects were most pronounced when the target species' growth was at its peak and weakest when growing conditions were far from their ***: Climate modulates the effects of competition from neighbouring trees on the target tree and not the susceptibility of th

关键词： Competition coefficient Competition reduction Interspecific competition Intraspecific competition Mixing effects Mixed species forest Neighbourhood models Plant-plant interactions

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