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Application of double-balloon enteroscopy in the diagnosis and therapy of small intestinal diseases

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Chinese Medical Journal 2007年第23期120卷 2075-2080页

作者： WU Cheng-rong HUANG Liu-ye SONG bo YI long-zhi CUI Jun Department of Gastroenterology Yantai Yuhuangding HospitalAffiliated to Medical College of Qingdao University Yantai264000 China

Background X-ray of the digestive tract and radionuclide examination could not accurately detect diseases of the small intestine. Double-balloon enteroscopy has been used to increase the detection rate of these diseases in addition to endoscopic biopsy and therapy. The purpose of this study was to determine the value of double-balloon enteroscopy in the diagnosis and treatment of diseases of the small intestine. Methods A total of 258 double-balloon enteroscopies via the mouth and/or anus were performed in 208 patients. If no lesion was detected on one side （mouth or anus）, examination on the other side （anus or mouth） was made. If active small intestinal bleeding was detected, endoscopic hemostasis was done to treat the bleeding. Results In the 208 patients, 50 were subjected to double-balloon enteroscopy via both mouth and anus. Lesions were detected in 151 patients, giving a rate of 72.6% （151/208）. The detection rates for obscure digestive tract bleeding, diarrhea, abdominal pain and weight loss were 90.2% （92/102）, 64.9% （24/37）, 48.5% （16/33） and 43.3% （13/30）, respectively. Lesions of the 151 patients were confirmed by endoscopic biopsy, surgery, clinical studies, and follow-up. In the 102 patients with bleeding of the digestive tract, active bleeding was detected in 27 patients. Endoscopic hemostasis was successful in 25 of them （92.6%, 25/27）. No serious complications occurred in all the patients, the average time for the procedure was 100 minutes. Conclusions Double-balloon enteroscopy is safe, effective in the diagnosis of diseases of the small intestine in addition to endoscopic therapy.

关键词： double-balloon enteroscopy small intestinal disease diagnosis

带运输时间和一个不可用约束的两台平行机排序

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兰州大学学报（自然科学版） 2009年第4期45卷 140-144页

作者：陈伯龙兰州大学数学与统计学院兰州730000 兰州大学大气科学学院兰州730000

考虑了两台平行机的排序问题,其中一台机器带有一个固定的不可用约束区间,任务的加工是不可中断的,而且每一个任务带有一个运输时间,目标函数是最小化最大运输完工时间.这个问题是强NP-难的.提出一个最坏情况比是8/5的多项式时间近似算... 详细信息

考虑了两台平行机的排序问题,其中一台机器带有一个固定的不可用约束区间,任务的加工是不可中断的,而且每一个任务带有一个运输时间,目标函数是最小化最大运输完工时间.这个问题是强NP-难的.提出一个最坏情况比是8/5的多项式时间近似算法,并指出这个界是紧界.同时还用动态规划方法求解该问题.

关键词：不可用约束运输时间最坏情况比近似算法动态规划

Robotic-assisted low anterior resection for rectal cancer shows similar clinical efficacy to laparoscopic surgery: A propensity score matched study

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1558-1570页

作者： Shen-Xiang long Xin-Ning Wang Shu-bo Tian Yu-Fang Bi Shen-Shuo Gao Yu Wang Xiao-bo Guo Department of Gastrointestinal Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Nursing The People’s Hospital of Zhangqiu AreaJinan 250200Shandong ProvinceChina Medical Center for Gastrointestinal Surgery Weifang People’s HospitalWeifang 261000Shandong ProvinceChina

BACKGROUND Rectal cancer ranks as the second leading cause of cancer-related mortality worldwide,necessitating surgical resection as the sole treatment *** the years,there has been a growing adoption of minimally invasive surgical techni-ques such as robotic and laparoscopic *** surgery represents an innovative modality that effectively addresses the limitations associated with traditional laparoscopic *** previous studies have reported favo-rable perioperative outcomes for robot-assisted radical resection in rectal cancer patients,further evidence regarding its oncological safety is still *** To conduct a comparative analysis of perioperative and oncological outcomes between robot-assisted and laparoscopic-assisted low anterior resection(LALAR)*** The clinical data of 125 patients who underwent robot-assisted low anterior resection(RALAR)and 279 patients who underwent LALAR resection at Shandong Provincial Hospital Affiliated to Shandong First Medical University from December 2019 to November 2022 were retrospectively *** performing a 1:1 propensity score matching,the patients were divided into two groups:The RALAR group and the LALAR group(111 cases in each group).Subsequently,a comparison was made between the short-term outcomes within 30 d after surgery and the 3-year survival outcomes of these two *** Compared to the LALAR group,the RALAR group exhibited a significantly earlier time to first flatus[2(2-2)d vs 3(3-3)d,P=0.000],as well as a shorter time to first fluid diet[4(3-4)d vs 5(4-6)d,P=0.001].Additionally,the RALAR group demonstrated reduced postoperative indwelling catheter time[2(1-3)d vs 4(3-5)d,P=0.000]and decreased length of hospital stay after surgery[5(5-7)d vs 7(6-8)d,P=0.009].Moreover,there was an observed increase in total cost of hospitalization for the RALAR group compared to the LALAR group[10777(10780-11850)dollars vs 10550(8766-11715)dollars,P=0.012].No signi

关键词： Rectal cancer Robotic surgical procedures Laparoscopy Low anterior resection Clinical efficacy

Highly efficient photo-thermal synergistic catalysis of CO_(2)methanation over La_(1-x)Ce_(x)NiO_(3)perovskite-catalyst

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Nano Research 2024年第9期17卷 7945-7956页

作者： Ting Li Zhen-Yu Zhang De-Cun Luo bo-Yu Xu Rong-Jiang Zhang Ji-long Yao Dan Li Tao Xie Institute of Industrial Catalysis School of Chemical Engineering and TechnologyXi’an Jiaotong UniversityXi’an 710049China

Solar-driven photo-thermal catalytic CO_(2)methanation reaction is a promising technology to alleviate the problems posed by greenhouse gases ***,designing advanced photo-thermal catalysts remains a research challenge for CO_(2)methanation *** this work,a series of Abo3(A=lanthanide,B=transition metal)perovskite catalysts with Ce-substituted LaNiO3(La_(1-x)Ce_(x)NiO_(3),x=0,0.2,0.5,0.8,1)were synthesized for CO_(2)*** La_(0.2)Ce_(0.8)NiO_(3) exhibited the highest CH_(4) formation rate of 258.9 mmol·g^(-1)·hcat-1,CO_(2)conversion of 55.4%and 97.2%CH_(4) selectivity at 300℃with the light intensity of 2.9 W·cm^(-2).Then the catalysts were thoroughly analyzed by physicochemical structure and optical properties *** partial substitution of the A-site provided more active sites for the adsorption and activation of CO_(2)/H_(2).The sources of the active sites were considered to be the oxygen vacancies(O_(v))created by lattice distortions due to different species of ions(La^(3+),Ce^(4+),Ce^(3+))and exsolved Ni0 by H_(2)*** catalysts have excellent light absorption absorbance and low electron-hole(e^(-)/h^(+))recombination rate,which greatly contribute to the excellent performance in photo-thermal synergistic catalysis(PTC)CO_(2)*** results of in situ irradiated electron paramagnetic resonance spectrometer(ISI-EPR)and ISI-X-ray photoelectron spectroscopy(XPS)indicated that the aggregation of unpaired electrons near the defects and Ni metal(from La and Ce ions to Ov and Ni0)accelerated adsorption and activation of CO_(2)/H_(2).At last,the catalyst properties and structure were correlated with the proposed reaction mechanism from the in situ diffuse reflection infrared Fourier transform spectrum(DRIFTS)*** in situ precipitation of the B-site enhanced the dispersion of Ni,while its enriched photoelectrons upon illumination further promote hydrogen *** H^(*)spillover accelerated t

关键词： photo-thermal catalysis CO_(2)methanation perovskite A-site substitution in situ diffuse reflection infrared Fourier transform spectrum(DRIFTS)

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神经外科护士伦理敏感性现状及影响因素研究

护理管理杂志 2024年第1期24卷 6-10页

作者：黄斌陈偶英张茜龙波陈晓霞李婵吴景张汝桢欧阳海艳湖南中医药大学护理学院长沙市410036 中南大学湘雅二医院肿瘤中心长沙市410012 湖南中医药大学第一附属医院神经外科长沙市410007 湖南省脑科医院中心重症监护室长沙市410021 中南大学湘雅二医院神经外科长沙市410012 长沙市中心医院神经外科 410028 湖南省脑科医院神经外科长沙市410021

目的调查神经外科护士伦理敏感性现状,分析其影响因素,为管理者制订针对性措施,提高护士伦理敏感性水平提供依据。方法采用一般资料调查问卷、中文版护士伦理敏感性问卷、医院伦理氛围量表、杰弗逊共情量表对长沙市3所三级甲等综合医院... 详细信息

目的调查神经外科护士伦理敏感性现状,分析其影响因素,为管理者制订针对性措施,提高护士伦理敏感性水平提供依据。方法采用一般资料调查问卷、中文版护士伦理敏感性问卷、医院伦理氛围量表、杰弗逊共情量表对长沙市3所三级甲等综合医院197名神经外科护士进行调查。结果神经外科护士伦理敏感性得分为(35.20±7.57)分,医院伦理氛围得分为(91.50±13.95)分,共情得分为(75.78±12.04)分;神经外科护士伦理敏感性与医院伦理氛围及共情得分均呈正相关(r_(1)=0.597,r_(2)=0.679,均P<0.01)。多元线性回归分析显示,护龄、工作强度、伦理道德教育经历、医院伦理氛围、共情是神经外科护士伦理敏感性的影响因素(P<0.05)。结论神经外科护士伦理敏感性处于中等水平,护龄短、工作强度大、无伦理道德教育经历、医院伦理氛围差、共情能力弱的护士伦理敏感性低,管理者应重视并制订针对性干预措施进一步提高其伦理敏感性。

关键词：神经外科护士伦理敏感性医院伦理氛围共情能力

Thermal properties of closed-cell aluminum foams prepared by melt foaming technology

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Transactions of Nonferrous Metals Society of China 2016年第12期26卷 3147-3153页

作者： Hui WANG Xiang-yang ZHOU bo long Juan YANG Hong-zhuan LIU School of Metallurgy and Environment Central South University Changsha 410083 China

Closed-cell aluminum foam has incomparable advantages over other traditional materials for thermal insulation and heatpreservation because of small thermal conductivity coefficient. Spherical bubble three-dimensional model of aluminum foam is builtto deduce the relationship among pore wall thickness, porosity and average pore size. Non-uniform closed-cell foam aluminummodel with different structural parameters and random pore distribution is established based on the relationship via C programminglanguage. And the temperature distribution is analyzed with ANSYS software. Results indicate that thermal conductivity increaseswith the reducing of porosity. For the aluminum foam with the same porosity, different pore distributions result in different thermalconductivities. The temperature distribution in aluminum foam is non-uniform, which is closely related with the pore size anddistribution. The pores which extend or distribute along the direction perpendicular to heat flow strengthen obstructive capability forheat flow. When pores connect along the direction perpendicular to heat flow, a “wall of high thermal resistance” appears to declinethe thermal conductivity rapidly, which shows that only porosity cannot completely determine effective thermal conductivity ofclosed-cell aluminum foam.

关键词： closed-cell aluminum foam thermal conductivity porosity pore distribution temperature distribution

Fabrication of a 3D bioprinting model for posterior capsule opacification using GelMA and PLMA hydrogel-coated resin

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Regenerative Biomaterials 2024年第4期3卷 52-65页

作者： Xin Liu Jiale Li Shuyu Liu Yan long Ching Kang Chen Zhao Ling Wei Shaoqi Huang Yi Luo bo Dai Xiangjia Zhu Cataract and Lens Refractive Surgery Group Department of OphthalmologyEye&ENT Hospital of Fudan UniversityShanghai 200031People’s Republic of China NHC Key Laboratory of Myopia Key Laboratory of MyopiaChinese Academy of Medical SciencesFudan UniversityShanghai 200031People’s Republic of China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031People’s Republic of China Engineering Research Center of Optical Instrument and System the Ministry of EducationShanghai Key Laboratory of Modern Optical SystemUniversity of Shanghai for Science and TechnologyShanghai 200093China

Posterior capsule opacification(PCO)remains the predominant complication following cataract surgery,significantly impairing visual function *** this study,we developed a PCO model that closely mimics the anatomical structure of the crystalline lens capsule *** model incorporated a threaded structure for accurate positioning and observation,allowing for opening and *** 3D printing technology,a stable external support system was created using resin material consisting of a rigid,hollow base and *** replicate the lens capsule structure,a thin hydrogel coating was applied to the resin *** biocompatibility and impact on cellular functionality of various hydrogel compositions were assessed through an array of staining techniques,including calcein-AM/PI staining,rhodamine staining,boDIPY-C11 staining and EdU staining in conjunction with transwell ***,the PCO model was utilized to investigate the effects of eight drugs with anti-inflammatory and anti-proliferative properties,including 5-aminoimidazole-4-carboxamide ribonucleotide(AICAR),THZ1,sorbinil,4-octyl itaconate(4-OI),xanthohumol,zebularine,rapamycin and caffeic acid phenethyl ester,on human lens epithelial cells(HLECs).Confocal microscopy facilitated comprehensive imaging of the PCO *** results demonstrated that the GelMA 605%þPLMA 2%composite hydrogel exhibited superior biocompatibility and minimal lipid peroxidation levels among the tested ***,compared to using hydrogel as the material for 3D printing the entire model,applying surface hydrogel spin coating with parameters of 2000 rpm�2 on the resin-based 3D printed base yielded a more uniform cell distribution and reduced ***,rapamycin,4-OI and AICAR demonstrated potent antiproliferative effects in the drug intervention *** microscopy imaging revealed a uniform distribution of HLECs along the anatomical structure of the crystalline lens capsule with

关键词： posterior capsule opacification(PCO) human lens epithelial cells(HLECs) 3D bioprinting hydrogel resin

A new infrageneric classification of Gastrochilus(Orchidaceae:Epidendroideae)based on molecular and morphological data

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Plant Diversity 2024年第4期46卷 435-447页

作者： Jun-Yi Zhang Yue-Hong Cheng Min Liao Yu Feng Sen-long Jin Ting-Mei He Hai He bo Xu China-Croatia“Belt and Road”Joint Laboratory on Biodiversity and Ecosystem Services CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan ProvinceChengdu Institute of BiologyChinese Academy of SciencesP.O.Box 416Chengdu 610041SichuanChina College of Life Sciences Chongqing Normal UniversityChongqing 401331China Wolong National Natural Reserve Administration Bureau Wenchuan 623006SichuanChina University of Chinese Academy of Sciences Beijing 100049China

Gastrochilus is an orchid genus containing 73 species of mainly epiphytic on trees or rocks in mountain forests of tropical and subtropical *** phylogenetic analyses and morphological assessments have failed to produce a well-resolved phylogeny at the infrageneric *** the present study,a new infrageneric classification of Gastrochilus is proposed based on thoroughly morphological and phylogenetic analyses based on 52 *** phylogenetic analysis divided the genus into six sections including three new sections,***,*** and *** also reinstate *** to the specific ***,two new species,*** Jun ***,***&Yue *** and *** Jun ***,***&Yue ***,are described and illustrated.A key to six sections of the genus is presented.

关键词： Gastrochilus Phylogeny Character evolution Taxonomy New species

Metabotropic glutamate receptors(mGluRs)in epileptogenesis:an update on abnormal mGluRs signaling and its therapeutic implications

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Neural Regeneration Research 2024年第2期19卷 360-368页

作者： Leyi Huang Wenjie Xiao Yan Wang Juan Li Jiaoe Gong Ewen Tu Lili long bo Xiao Xiaoxin Yan Lily Wan Department of Anatomy and Neurobiology Central South University Xiangya Medical SchoolChangshaHunan ProvinceChina Department of Neurology Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Neurology Hunan Children’s HospitalChangshaHunan ProvinceChina Department of Neurology Brain Hospital of Hunan ProvinceChangshaHunan ProvinceChina

Epilepsy is a neurological disorder characterized by high morbidity,high recurrence,and drug *** signaling through the excitatory neurotransmitter glutamate is intricately associated with *** glutamate receptors(mGluRs)are G protein-coupled receptors activated by glutamate and are key regulators of neuronal and synaptic *** mGluR signaling has been associated with various neurological disorders,and numerous studies have shown a close relationship between mGluRs expression/activity and the development of *** this review,we first introduce the three groups of mGluRs and their associated signaling ***,we detail how these receptors influence epilepsy by describing the signaling cascades triggered by their activation and their neuroprotective or detrimental roles in *** addition,strategies for pharmacological manipulation of these receptors during the treatment of epilepsy in experimental studies is also *** hope that this review will provide a foundation for future studies on the development of mGluR-targeted antiepileptic drugs.

关键词： antiepileptic drugs epileptogenesis metabotropic glutamate receptors(mGluRs) signal pathways therapeutic potentials