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Some Developments in Nielsen Fixed Point Theory

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Acta Mathematica Sinica,English Series 2018年第1期34卷 91-102页

作者： bo ju jiang Xue Zhi ZHAO School of Mathematical Sciences Peking University Department of Mathematics Capital Normal University

We give a brief survey of some developments in Nielsen fixed point theory. After a look at early history and a digress to various generalizations, we confine ourselves to several topics on fixed points of self-maps on manifolds and polyhedra. Special attention is paid to connections with geometric group theory and dynamics, as well as some formal approaches.

关键词： Fixed points Nielsen theory

Case Report： Concurrent pulmonary thrombosis with systemic embolism： a case report

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2014年第9期15卷 838-844页

作者： Xiao-jie XIE ju-bo jiang jun jiang Jian-an WANG Department of Cardiology the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

Based on different mechanisms of blood coagulation, coexistence of venous thromboembolism and arterial thrombosis in a single individual is extremely rare in clinical practice. both antiplatelet and anticoagulation therapy should be adopted for patients with arteriovenous embolism. Balancing the risk of ischemia and hemorrhage is especially challenging in these patients in order to achieve an optimal clinical benefit. We report on a 55-year-old female with acute pulmonary embolism （PE）, subsequently diagnosed as having acute myocardial infarction （AMI） and a cerebral infarction. Examinations had been carried out, excluding potential arteriovenous shunts, cancer, an- tiphospholipid syndrome and other common hypercoagulable states. A combination of an anticoagulant drug （rivaroxaban, an Xa inhibitor） and an antiplatelet agent （clopidogrel, an ADP receptor inhibitor） was prescribed with a β-blocker and atorvastatin. The embolus was gradually shrunk during the next 10 months, and then it turned back into expanding. During the 16 months＇ follow-up, an aneurysm of left ventricular apex was found through an echocardiogram and an angiotensin-converting enzyme inhibitor was administered. We conclude that combined anticoagulation and antiplatelet therapy significantly relieved the symptoms and improved the prognosis in patients suffering from arteriovenous embolism without any major clinical bleeding events.

关键词： Pulmonary thrombosis Cerebral infarction Acute myocardial infarction (AMI) Ventricular aneurysm

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肺栓塞合并体循环栓塞的个案报道(英文)

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2014年第9期15卷 838-844页

作者： Xiao-jie XIE ju-bo jiang jun jiang Jian-an WANG Department of Cardiology the Second Affiliated HospitalSchool of MedicineZhejiang University

研究目的:通过一例罕见肺栓塞合并体循环栓塞病例报道及定期随访,为临床诊断思路和合理治疗方案的制定提供依据。研究方法:本文报道一例在急诊室发生急性肺动脉栓塞,后继又出现急性心肌梗死和脑梗塞的病例。患者住院期间接受了严密监护... 详细信息

研究目的:通过一例罕见肺栓塞合并体循环栓塞病例报道及定期随访,为临床诊断思路和合理治疗方案的制定提供依据。研究方法:本文报道一例在急诊室发生急性肺动脉栓塞,后继又出现急性心肌梗死和脑梗塞的病例。患者住院期间接受了严密监护并排除各种病因,出院后随访16个月,动态观察肺动脉栓塞病情的进展和心脏重构的过程(如图3)。结果显示,早期溶栓治疗,合理进行抗凝和抗血小板为主的综合治疗能显著缓解患者症状,改善生活质量和预后。重要结论:临床上动静脉系统同时发生栓塞虽然比较罕见,但仍需提高警惕并及早诊断,早期进行合理的治疗。抗凝和抗血小板为主的联合治疗能显著改善症状,提高患者生活质量,改善预后。

关键词：肺栓塞脑梗塞急性心肌梗死室壁瘤

Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement

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World Journal of Emergency Medicine 2022年第1期13卷 32-39页

作者： Stella Ng Qi-feng Zhu ju-bo jiang Chun-hui Liu Jia-qi Fan Ye-ming Xu Xian-bao Liu Jian-an Wang Department of Cardiology the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhou 310009China Zhejiang University School of Medicine Hangzhou 310058China

BACKGROUND: Anemia is prevalent in patients undergoing transcatheter aortic valve replacement(TAVR) and has been linked to impaired outcomes after the procedure. Few studies have evaluated the impact of anemia and new ischemic lesions post ***: We prospectively enrolled 158 patients who received TAVR in our center. Anemia was defined according to the World Health Organization criteria as hemoglobin <12 g/dL in women and <13 g/dL in men. All patients underwent diffusion-weighted magnetic resonance imaging(DW-MRI) procedure before and within 4–7 days after TAVR. RESULTS: Anemia was present in 85(53.8%) patients who underwent TAVR, and 126(79.7%) patients had 718 new DW-MRI positive lesions with a mean of 4.54±5.26 lesions per patient. The incidence of new ischemic lesions was 81.2% in patients with anemia versus 78.1% in patients without anemia(P=0.629). Moreover, anemic patients had bigger total volume/lesions in the anterior cerebral artery/middle cerebral artery(ACA/MCA) and MCA regions compared to the non-anemic patients(31.89±55.78 mm^(3) vs. 17.08±37.39 mm^(3), P=0.049;and 54.54±74.72 mm^(3) vs. 33.75±46.03 mm^(3), P=0.034). Anemia was independently associated with the volume/lesion in the ACA/MCA(β=16.796, 95% confidence interval [95% CI] 2.001 to 31.591, P=0.026) and in the MCA zone(β=0.020, 95% CI 0.001 to 0.040, P=0.041). CONCLUSIONS: Patients with pre-procedural anemia may have bigger total volume/lesions in the ACA/MCA and MCA regions compared to the non-anemic patients. Whether the consequences of bigger total volume/lesions impact neurological and cognitive outcomes remains to be investigated.

关键词： Aortic stenosis Anemia Cerebral ischemic lesions Transcatheter aortic valve replacement

Ascending aortic dilatation rate after transcatheter aortic valve replacement in patients with bicuspid and tricuspid aortic stenosis: A multidetector computed tomography follow-up study

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World Journal of Emergency Medicine 2019年第4期10卷 197-204页

作者： Yu-xin He Jia-qi Fan Qi-feng Zhu Qi-jing Zhou ju-bo jiang Li-han Wang Stella Ng Xian-bao Liu Jian-an Wang Department of Cardiology the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Radiology the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China

BACKGROUND: Current data is lacking about the progression of ascending aortic dilatation after transcatheter aortic valve replacement(TAVR) in aortic stenosis(AS) patients with bicuspid aortic valve(BAV) and tricuspid aortic valve(TAV). This study aims to assess the ascending aortic dilatation rate(mm/year) after TAVR in patients with BAV versus TAV using a multidetector computed tomography(MDCT) fol ow-up and to determine the predictors of ascending aortic dilatation ***: Severe AS patients undergoing TAVR from March 2013 to March 2018 at our center with MDCT follow-ups were included. BAV and TAV were identified using baseline MDCT. Baseline and follow-up MDCT images were analyzed,and the diameters of ascending aorta were measured. Study end point is ascending aortic dilatation rate(mm/year). Furthermore,factors predicting ascending aortic dilatation rate were also ***: Two hundred and eight patients were included,comprised of 86 BAV and 122 TAV patients. Five,4,3,2,and 1-year MDCT follow-ups were achieved in 7,9,30,46,and 116 patients. The ascending aortic diameter was significantly increased after TAVR in both BAV group(43.7±4.4 mm vs. 44.0±4.5 mm;P<0.001) and TAV group(39.1±4.8 mm vs. 39.7±5.1 mm;P<0.001). However,no difference of ascending aortic dilatation rate was found between BAV and TAV group(0.2±0.8 mm/year vs. 0.3±0.8 mm/year,P=0.592). Multivariate linear regression revealed paravalvular leakage(PVL) grade was independently associated with ascending aortic dilatation rate in the whole population and BAV group,but not TAV group. No aortic events occurred during ***: Ascending aortic size continues to grow after TAVR in BAV patients,but the dilatation rate is mild and comparable to that of TAV patients. PVL grade is associated with ascending aortic dilatation rate in BAV patients post-TAVR.

关键词： Transcatheter aortic valve replacement Aortic dilatation Bicuspid aortic valve

Treatment of a dyeing wastewater from a woolen mill using an A/O membrane bio-reactor

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Journal of Environmental Sciences 2000年第3期12卷 344-348页

An anaerobic/oxic membrane bioreactor (A/O MBR) was used for treatment of dyeing wastewater from a woolen mill. COD and color of the wastewater were 54—473 mg/L and 40—400 dilution time (DT) respectively. The ratio of boD 5/COD was less than 0.13. By the A/O MBR process, the average removal of COD, boD 5, color and turbidity was 82%, 96%, 71% and 99%, respectively. The average COD, boD 5, color and turbidity of effluent was 37 mg/L, 0.8 mg/L, 40 DT and 0.44 NUT respectively. The effluent COD met the local standard of reuse water in Beijing, China. The average COD volume load of the anaerobic biological tank was 0.0483 kgCOD/(m 3·d) and that of the aeration tank of the MBR was 0.3589 kgCOD/(m 3·d). The sludge load of the MBR was 0.19 kgCOD/(kg·MLSS·d) on average and the maximum of that was 0.4 kgCOD/(kg·MLSS·d). The flux of the A/O membrane bioreactor could be remained at larger than 50 L/(h·m 2·0.1MPa). The results indicated that A/O membrane bioreactor has technical feasibility for treatment of woolen mill wastewater.

关键词： membrane bioreactor dyeing wastewater biological process membrane technology activated sludge

The first four cases of successful NeoChord procedure in Chinese mainland

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World Journal of Emergency Medicine 2019年第3期10卷 133-137页

作者： Li-han Wang Zhao-xia Pu Min-jian Kong ju-bo jiang Kai-da Ren Feng Gao Xin-ping Lin Lei Yu Wei He Min Yan Xian-bao Liu Jian-an Wang Cardiovascular Department the Second Affiliated HospitalZhejiang University School of Medicine

BACKGROUND:Transapical off-pump NeoChord procedure is a novel minimally invasive surgical repair of degenerative mitral regurgitation(MR).Here,we report the first four cases of NeoChord procedure in patients with mitral valve prolapse in Chinese ***:Four patients,aged 86,84,80 and 60 years,with severe MR due to posterior middle scallop prolapse(P2),underwent transapical off-pump artifi cial chordae implantation on April 9 and 10,*** procedure was performed by left mini-thoracotomy under general anaesthesia and guided by 2D and 3D dimensional transoesophageal echocardiography(TEE).RESULTS:Mitral valve repair via NeoChord procedure was successfully performed with implantation of 3 artifi cial chordae in the fi rst patient and 3,2,and 3 artifi cial chordae in the following patients,*** TEE and pre-discharge transthoracic echocardiography(TTE)showed only mild to moderate MR of these four patients and no postoperative complications were *** were no changes of TTE fi nding between one-month follow-up and ***:The successful NeoChord procedures in four Chinese indicate that the valve repair using the NeoChord system for Chinese population is feasible.

关键词： Mitral regurgitation Mitral valve repair NeoChord system

The first two cases of transcatheter mitral valve repair with ARTO system in Asia

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World Journal of Emergency Medicine 2020年第1期11卷 33-36页

作者： Kai-da Ren Zhao-xia Pu Lei Yu Feng Gao Li-han Wang Stella Ng ju-bo jiang Hua-jun Li Yong Xu Wei He Min Yan Xian-bao Liu Jian-an Wang Cardiovascular Department the Second Affiliated Hospital Zhejiang University School of Medicine

BACKGROUND:MAVERIC(Mitral Valve Repair Clinical Trial)validates the safety and effi cacy of the ARTO *** here report the fi rst two successful cases of utilizing the ARTO system in patients with symptomatic heart failure(HF)with functional mitral regurgitation(FMR)in ***:Two patients,aged 70 and 63,had severe HF with *** echocardiography confirmed that the left ventricular ejection fractions were less than 50%with severe mitral regurgitation(MR)in both *** drug treatment could not mitigate their ***,we used the ARTO system to repair the mitral valve for these patients on March 5 and 6,2019,***:Mitral valve repairs using the ARTO system were successfully performed under general anaesthesia for these two *** was decreased immediately after the procedures in both *** 30-day and 3-month transthoracic echocardiography(TTE)revealed a moderate to severe MR in both patients,and the New York Heart Association(NYHA)scales were also partially ***:The first two cases in Asia indicate that the ARTO system is feasible for patients with heart failure with FMR,and the patient selection appears to be crucial.

关键词： Mitral regurgitation Mitral valve repair ARTO system

Effect of Tai Chi exercise on blood lipid profiles: a meta-analysis of randomized controlled trials

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2016年第8期17卷 640-648页

作者： Xiao-hong PAN Amina MAHEMUTI Xue-hua ZHANG Ya-ping WANG Po HU ju-bo jiang Mei-xiang XIANG Gang LIU Jian-an WANG Department of Cardiology the Second Affiliated Hospital School of Medicine Zhejiang University Department of Cardiology the First People's Hospital of Aksu District in Xinjiang Uygur Autonomous Region

Objective： Studies have demonstrated that Tai Chi exercise improves blood lipid level with inconsistent results. A meta-analysis was conducted to quantify the effects of Tai Chi on blood lipid profiles in humans. Methods： We screened the databases of PubMed, EMBASE, Cochrane Library （Central）, Web of Science, China National Knowledge Infrastructure （CNKI）, Wanfang data, and *** for randomized controlled trials with Physio- therapy Evidence Database （PEDro） score more than 3 points up to june 2015. Six studies involving 445 subjects were included. Most trials applied 12-week Tai Chi intervention courses. Results： In comparison with the control group, blood triglyceride （TG） level difference between follow-up and baseline was statistically significantly lower in the Tai Chi practicing group （weighted mean difference （WMD） -16.81 mg/dl; 95% confidence intervals （CI） -31.27 to -2.35 mg/dl; P=-0.02）. A trend to improving total cholesterol （TC） reduction was found with Tai Chi （WMD -7.96 mg/dl; 95% CI -17.30 to 1.39 mg/dl; P=-0.10）. However, no difference was found in blood low-density lipoprotein cholesterol （LDL-C） or high-density lipoprotein cholesterol （HDL-C）. Conclusions： Tai Chi exercise lowered blood TG level with a trend to decrease blood TC level. Our data suggest that Tai Chi has the potential to implement meaningful blood lipid modification and serve as an adjunctive exercise modality. The relationship between Tai Chi exercise regimen and lipid profile change might have a scientific priority for future investigation.

关键词： Tai Chi Blood lipid Triglycerides Meta-analysis