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Improving treatment plan and mental health in children with abdominal infection for broad-spectrum bacterial infections

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World Journal of Psychiatry 2024年第9期14卷 1319-1325页

作者： gui-bo Wang Xue-Feng Zhang Bing Liang Jie Lei Jun Xue Department of Pediatric Surgery the First Affiliated Hospital of Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Department of General Surgery the First Affiliated Hospital of Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina

BACKGROUND Pediatric abdominal infection is a common but serious disease that requires timely and effective *** surgical treatment,accurate diagnosis and rational application of antibiotics are the keys to improving treatment *** To investigate the effect of broad-spectrum bacterial detection on postoperative antibiotic *** A total of 100 children with abdominal infection who received surgical treatment in our hospital from September 2020 to July 2021 were *** observation group collected blood samples upon admission and sent them for broad-spectrum bacterial infection nucleic acid testing,and collected pus or exudate during the operation for bacterial culture and drug sensitivity testing;the control group only sent bacterial culture and drug sensitivity testing during the *** White blood cell count,C-reactive protein,procalcitonin,3 days after surgery,showed better postoperative index than the control group(Pguide the appropriate use of antibiotics,improving treatment outcomes and reducing medical costs to some extent.

关键词： Pediatric abdominal infection Nucleic acid detection of broad-spectrum bacterial infection Bacterial culture Drug sensitivity testing Treatment effect Cost Mental health

习近平关于道德治理重要论述的时代意涵、关系结构及目标指向

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石河子大学学报（哲学社会科学版） 2024年第3期38卷 38-44页

作者：邹贵波电子科技大学马克思主义学院四川成都611731 贵州师范大学贵州阳明文化研究院贵州贵阳550001

道德治理作为利益分歧、价值纷争与思想分化境遇下聚焦道德领域突出问题和明显短板的独特性道德建设活动,其不仅是一场以惩恶扬善为目标的精神洗礼,更是一次以提升道德境界为主题的伦理觉醒。党的十八大以来,习近平总书记将马克思主义... 详细信息

道德治理作为利益分歧、价值纷争与思想分化境遇下聚焦道德领域突出问题和明显短板的独特性道德建设活动,其不仅是一场以惩恶扬善为目标的精神洗礼,更是一次以提升道德境界为主题的伦理觉醒。党的十八大以来,习近平总书记将马克思主义道德观同中国道德实际相结合、同中华优秀传统道德相结合,以核心价值导向作为道德治理的灵魂、维护共同利益作为道德治理的根本、丰富精神世界作为道德治理的主题,形成了人民治理、系统治理、科学治理相互支撑、有机衔接、同向同行的中国特色道德治理模式,不断赋予道德治理鲜明价值追求、构筑道德治理完整制度体系、推动道德治理生动社会实践,实现了以德立人、以德兴国与以德强党的道德治理目标。

关键词：习近平道德治理道德建设

核心素养培养在“三步九核”教学法的探索与实践——以“洗涤剂和化妆品生产实训”课程为例

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南方职业教育学刊 2024年第1期14卷 66-76页

作者：江贵波黄丹莹揭阳职业技术学院化学工程系广东揭阳522000

为落实教育部关于全面深化课程改革、落实立德树人根本任务的要求,以“洗涤剂和化妆品生产实训”课程教学为依托,以核心素养培养为主,任务驱动的项目教学为辅,结合高职院校的课程特点和学生的职业需求与岗位实际,对教学内容进行模块化整... 详细信息

为落实教育部关于全面深化课程改革、落实立德树人根本任务的要求,以“洗涤剂和化妆品生产实训”课程教学为依托,以核心素养培养为主,任务驱动的项目教学为辅,结合高职院校的课程特点和学生的职业需求与岗位实际,对教学内容进行模块化整合,提出了“三步九核”项目任务驱动教学法。探索与实践证明,“三步九核”项目任务驱动教学法将核心素养融入课堂,推动课堂转型,贴近岗位实际,较好地培养和发展学生的核心素养,实施效果显著,有助于培养学生的核心素养和科研实践创新能力。

关键词：核心素养 “三步九核” 项目教学化妆品洗涤剂

Storage life prediction under pre-strained thermally-accelerated aging of HTPB coating using the change of crosslinking density

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Defence Technology（防务技术） 2021年第4期17卷 1387-1394页

作者： Yong-qiang Du Jian Zheng gui-bo Yu Shijiazhuang Campus Army Engineering UniversityShijiazhuang050003China

In order to predict the storage life of a certain type of HTPB(hydroyl-terminated polybutadiene)coating at 25℃ and analyze the influence of pre-strain on the storage life,the accelerated aging tests of HTPB coating at 40℃,50℃,60℃,70℃ with the pre-strain of 0%,3%,6%,9%,respectively were carried *** variation regularity of the change of crosslinking density was analyzed and the aging model of HTPB coating under pre-strained thermally-accelerated aging was *** storage life of HTPB coating at 25℃ was estimated by using the Berthelot equation as the end point of the aging life with a 30% decrease in maximum *** results showed that the change of crosslinking density of HTPB coating increased with the increase of aging temperature and aging time,and decreased with the increase of *** 0% prestrain,the relationship between the change of crosslinking density of HTPB coating and the aging time can be described by the logarithmic model with the confidence probability greater than 99%.The stress relaxation phenomenon existed under 3%,6%and 9%pre-strained *** aging model considering chemical aging and pre-strain was established with the confidence probability greater than 90%.The storage life of HTPB coating was 15.2935 years at 25C under 0% prestrain,which was reduced by 13.9007%,75.6949% and 89.7859% under 3%,6% and 9% pre-strain,*** existence of pre-strain has a serious impact on the storage life of HTPB coating,therefore,the pre-strain should be avoided as much as possible during the actual storage.

关键词： HTPB coating Crosslinking density Aging model Storage life prediction Berthelot

Logistic回归和机器学习模型预测胸腔镜肺部分切除术患者单肺通气期间低SpO_(2)的比较

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临床麻醉学杂志 2024年第10期40卷 1022-1028页

作者：许斯洋王君渠磊秋桂波阮姗南京医科大学附属老年医院麻醉疼痛科 210024

目的比较Logistic回归和机器学习模型对胸腔镜肺部分切除术(TPPR)患者单肺通气(OLV)期间发生低SpO_(2)的预测效能,并探讨低SpO_(2)的危险因素。方法选择2022年8月1日至2023年4月30日行单侧TPPR患者127例,男61例,女66例,年龄18~80岁,ASA... 详细信息

目的比较Logistic回归和机器学习模型对胸腔镜肺部分切除术(TPPR)患者单肺通气(OLV)期间发生低SpO_(2)的预测效能,并探讨低SpO_(2)的危险因素。方法选择2022年8月1日至2023年4月30日行单侧TPPR患者127例,男61例,女66例,年龄18~80岁,ASAⅠ—Ⅲ级。根据术中OLV期间是否出现SpO_(2)boost)、决策树(DT)、逻辑回归(LogR)、支持向量机(SVM)5种机器学习模型构建的预测模型进行比较,绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC)评价预测模型的效能。采用沙普利加和解释法(SHAP)解释输出的最佳模型,确定TPPR患者OLV期间低SpO_(2)的危险因素。结果多因素Logistic回归分析显示,年龄增大(OR=1.087,95%CI 1.006~1.175,P=0.036)、BMI升高(OR=1.299,95%CI 1.050~1.608,P=0.016)、术前血糖浓度升高(OR=2.028,95%CI 1.378~2.983,Pboost的AUC为0.940(95%CI 0.812~0.981),DT的AUC为0.919(95%CI 0.828~0.982),LogR的AUC为0.892(95%CI 0.831~0.980),SVM的AUC为0.922(95%CI 0.832~0.982),XGboost预测的AUC最高,且高于传统的Logistic回归预测模型。经SHAP方法处理后,XGboost输出模型中最重要的危险因素是年龄增大、BMI和术前血糖浓度升高。结论年龄增大、BMI和术前血糖浓度升高是TPPR患者OLV期间低SpO_(2)的危险因素,机器学习模型XGboost预测OLV期间低SpO_(2)发生的效能优于传统的Logistic回归,能分析变量与结局间的复杂关系,更精准地个体化预测OLV期间低SpO_(2)的发生风险。

关键词：机器学习胸腔镜肺部分切除术单肺通气年龄体重指数血糖

Tuning Energy Transfer in Metal-OrganicFrameworks for Fluorescence Turn-on Sensing of Hg(Ⅱ)Ions

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Chinese Journal of Chemistry 2023年第9期41卷 1051-1056页

作者： Xuejiao Wang Arindam Mal bo gui Cheng Wang Sauvage Center for Molecular Sciences and Hubei Key Lab on Organic and Polymeric Optoelectronic Materials College of Chemistry and Molecular SciencesWuhan UniversityWuhanHubei 430072China

Tuning F?rster resonance energy transfer(FRET)in metal-organic frameworks for fluorescence turn on sensing is rarely ***,we designed and synthesized several FRET-based metal-organic frameworks(MOFs)with different donor/acceptor *** the oxidation of the acceptor,the FRET process in MOFs can be efficiently modulated so as to turn-on the fluorescence of the framework in a controlled ***,the MOF with an optimized donor/acceptor ratio of 7.0 was used as an efficient fluorescence turn on sensor for Hg(Ⅱ)ions with good sensitivity and *** believe our present study will not only give a useful method to construct fluorescence turn-on sensors but also trigger the construction of novel FRET-based MOFs for the fluo-rescence turn-on sensing of target analytes in the future.

关键词： Energy transfer FluorescenceHg(Ⅱ)ions Sensors Metal-organic frameworks

Spin Polarization Properties of Na Doped Meridianal Tris（8-Hydroxyquinoline） Aluminum Studied by First Principles Calculations

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Chinese Physics Letters 2014年第4期31卷 193-196页

作者： REN Jun-Feng YUAN Xiao-bo HU gui-Chao College of Physics and Electronics Shandong Normal University Jinan 250014

We theoretically investigate the electronic structure and spin polarization properties of Na-doped meridianal tris（S-hydroxyquinoline） aluminum （Alq3） by first principles calculations. It is found that the spin density is distributed mainly in the Alq3 part in the Alq3：Na complex. Electron charge transfer takes place from the Na atom to the Alq3 molecule, which induces asymmetric changing of the molecule bond lengths, thus the spin density distribution becomes asymmetric. Spin polarization of the complex originates from the preferable filling of the spin-split nitrogen and carbon p-orbitals because of the different bond length changes of the Aiq3 molecule upon Na doping.

关键词： SPIN polarization ELECTRONIC structure SODIUM -- Spectra SEMICONDUCTOR doping HYDROXYQUINOLINE CHARGE exchange

Transverse relaxation characteristic and stress relaxation model considering molecular chains of HTPB coating based on pre-strained thermal aging

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Defence Technology（防务技术） 2021年第3期17卷 821-828页

作者： Yong-qiang Du Jian Zheng gui-bo Yu Jian-zhuang Zhi Shijiazhuang Campus Army Engineering UniversityShijiazhuang050003China Intelligent Manufacturing Institute Hebei College of Industry and TechnologyShijiazhuang050003China

In order to accurately describe the transverse relaxation characteristic and stress relaxation modulus of HTPB coating during pre-strain thermal aging process,a one month thermal aging test was carried out at70C with pre-strain of 0%,3%,6%and 9%,*** low-field1 H NMR and stress relaxation modulus tests were carried out for HTPB coating at different aging *** stress relaxation model considering the molecular chains was proposed according to the changes of crosslinking chain and dangling chain of HTPB coating during pre-strain *** results showed that with the increase of aging time,the decay rate of transverse relaxation curve became faster,the transverse relaxation time decreased,the value of combined parameter q Mrl increased,the proportion of crosslinking chain decreased,while the proportion of dangling chain ***,the stress relaxation modulus increased,the crosslinking network structure of HTPB coating became denser and the degree of crosslinking *** the initial aging stage,the pre-strain will destroy the crosslinking network structure of HTPB coating to a certain *** the increase of aging time,the effect of pre-strain will gradually weaken and the influence of aging on materials will gradually *** correlations between the stress relaxation model considering the molecular chains and the test results were more than 0.9950,which can accurately describe the stress relaxation modulus of HTPB coating during the pre-strain thermal aging process.

关键词： HTPB Pre-strain aging Transverse relaxation characteristic Molecular chain Stress relaxation model

Postsynthetic Modification of Metal-Organic Frameworks through Click Chemistry

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Chinese Journal of Chemistry 2016年第2期34卷 186-190页

作者： bo gui Xiangshi Meng Hai Xu Cheng Wang Key Laboratory of Biomedical Polymers (Ministry of Education) College of Chemistry and Molecular Sciences Wuhan University Wuhan Hubei 430072 China College of Chemistry and Chemical Engineering Central South University Changsha Hunan 410083 China

The postsynthetic modification （PSM） of metal-organic frameworks （MOFs） has emerged as a powerful tool to chemically tailor the interior of MOFs. In this review, we summarize the research progress of PSM of MOFs t... 详细信息

关键词： postsynthetic modification metal-organic frameworks click chemistry azide-alkyne click reaction thiol-ene reaction