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Frequency and severity of OSAHS in Mexican adolescents. The role of BMI and neck circumference

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Health 2013年第8期5卷 1-8页

作者： Armando Partida-Gaytán Arturo Berber blanca Estela del Río-Navarro reyes Haro-Valencia Chief of Sleep Breathing Disorders Clinic Universidad Nacional Autónoma de México Hospital General de México Secretaria de Salud Distrito Federal México Departamento de Alergia e Inmunología Clínica Pediátrica Hospital Infantil de México Federico Gómez Instituto Nacional de Salud Secretaria de Salud Distrito Federal México

Background: Overweight and obesity are major public-health issues in Mexico. Sleep breathing disorders directly impact the health of affected subjects. The aim of this study was to describe the frequency and severity of obstructive sleep apnea/hypopnea syndrome (OSAHS) in Mexican adolescents grouped by weight status. Secondary objectives were to describe the influence of body mass index (BMI) and neck circumference (NC) as predictive factors of OSAH. Method: Somatometric, demographic data and full-night polysomnography were done. Linear and logistic regression models described the relationship between BMI and NC with OSAHS presence and severity. receiver-Operating-Characteristics (ROC) curves showed different sensitivity and specificity performances of BMI and NC cutoff-values. results: OSAHS frequency and severity were significantly greater in obese and extremely-obese adolescents (8% vs 22% vs 67%;p regression showed an AHI increase of 0.940 events/hour for every centimeter-increase in NC and 0.696 events/hour for every1 kg/m2-increase in BMI. Logistic-regression showed extreme-obesity as the main risk factor (OR 9.9) for diagnosis of OSAHS. ROC curves showed an area under the curve (AUC) of 0.83 for BMI defined cutoff-values, and of 0.80 for BMI percentile-for-age cutoff-values. The AUC of NC ROC curve was 0.8043. Conclusion: This is the largest study made on Latin-American population evaluating the frequency and severity of OSAHS with full-night polysomnography. We showed that obese and extremely-obese Mexican-adolescents are at highest risk for OSAHS. Increasing BMI and NC showed positive correlation with AHI. Different BMI cut-off values showed similar diagnostic performance. Extreme-obesity increases 8 times the risk association for OSAHS.

关键词： Obesity Obstructive Sleep Apnea Hyopopnea Syndrome (OSAHS) Obstructive Sleep Apnea Sleep Apnea Syndromes Polysomnography Body Mass Index (BMI) Neck Circumference Adolescents

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恋上萨里的阳光

现代装饰（家居） 2013年第9期 112-119页

作者： blanca Sanchez Robert Sanderson 肖俊英国Halo Design Interiors

本案是一栋建于2003年的房子,根据目前的房屋状况,急需对其进行个性化和现代化改造。业主是一对年轻夫妇和他们的两个小男孩。业主对本次改造的要求是对房屋进行全面更新的同时,着眼于对主卧套房的改造,使其纳入一个全新的卫浴间和更衣... 详细信息

本案是一栋建于2003年的房子,根据目前的房屋状况,急需对其进行个性化和现代化改造。业主是一对年轻夫妇和他们的两个小男孩。业主对本次改造的要求是对房屋进行全面更新的同时,着眼于对主卧套房的改造,使其纳入一个全新的卫浴间和更衣室。此外。

关键词：卫浴间主卧现代化改造萨里儿童房 patio kitchen 室内设计 floor 两层楼

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萨里初印象

现代装饰（家居） 2014年第3期 96-101页

作者： blanca Sanchez Roxanne Holland 肖俊英国Halo Design Interiors

本案是受乔治王时期艺术风格的启发而新建的一栋位于英国萨甩琊的宅邸。建筑的中央是一个全高的八角形中庭，源源不断的自然光线从中庭上方的灯笼窗口倾泻而下。

关键词：印象艺术风格自然光线中庭建筑

Triage and Risk Concept: Application Proposal for Pre-Hospital Emergencies in a Psychiatric Ambulance in the City of Buenos Aires

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Open Journal of Emergency Medicine 2023年第1期11卷 21-31页

作者： Mazzoglio Y. Nabar Martín Javier Rubén Daniel Algieri Gabriel Schraier blanca Lopez Sergio Giordano Department of Psychiatric Emergencies “Torcuato de Alvear” Psychiatric Emergency Hospital Buenos Aires Argentina

The heterogeneity of clinical presentations in psychiatric emergencies creates difficulties in the response by interdisciplinary Mental Health teams. This is aggravated and difficult when the care is carried out on public roads or the patient’s home, that is, it is a pre-hospital context. Our Psychiatric Emergency Hospital, located in the City of Buenos Aires, provides pre-hospital care with a psychiatric ambulance, which is then referred to general hospitals or other health system providers. Not all effectors in the network have the same resources and, at the time of the emergency, the reasons for consultation such as the patient’s clinic are heterogeneous and require the greatest effectiveness in the intervention that is taken. The triage system is a resource that allows the systematization of approaches against the multiplicity of reasons for consultation and presentation of mental pathologies in the emergency room, in addition to providing greater effectiveness in interventions, homogeneity for the health system and consensus among the health effectors. Framed in the Mental Health Law, and especially in the concept of risk, a triage proposal was designed for pre-hospital interventions by the psychiatric ambulance dependent on Hospital Alvear and under current legal regulations with the aim of homogenizing care and referrals with the highest rate of effectiveness to provide quality interdisciplinary medicine.

关键词： Psychiatry Ambulance Emergencies Triage

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馨雅时刻

现代装饰（家居） 2016年第8期 84-93页

作者： blanca Sanchez 范嘉苑英国Halo Design Interiors

项目地址英国设计单位Halo Design InteriorsHalo Design Interiors在近期翻新了一座建于80年代的独栋住屋。由于房子原来的厨房采用了封闭式的布局,看上去昏暗老旧,且对其它空间的布局也造成了影响,所以厨房成为了设计团队首先改造的... 详细信息

项目地址英国设计单位Halo Design InteriorsHalo Design Interiors在近期翻新了一座建于80年代的独栋住屋。由于房子原来的厨房采用了封闭式的布局,看上去昏暗老旧,且对其它空间的布局也造成了影响,所以厨房成为了设计团队首先改造的区域。通过移除厨房原先的两面墙体,使之拥有了开放式的格局,并与餐区及家庭活动室相连。厨房色调以白色及金色为主调,橱柜采用了哑光白及抛光金的质感与色调,并配备了纯白的光面操作台。经过改造后的厨房看起来更加干净明亮,营造出一种平和宁静的空间调性。

关键词：项目地址纯白英国设计过渡区主卧 kitchen interior bases bronze 觉木

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1.3 μm emitting SrF2：Nd^3＋ nanoparticles for high contrast in vivo imaging in the second biological window

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Nano research 2015年第2期8卷 649-665页

作者： Irene Villa Anna Vedda Irene Xochilt Cantarelli Marco Pedroni Fabio Piccinelli Marco Bettinelli Adolfo Speghini Marta Quintanilla Fiorenzo Vetrone Ueslen Rocha Carlos Jacinto Elisa Carrasco Francisco Sanz Rodrfguez Angeles Juarranz blanca del Rosal Dirk H. Ortgies Patricia Haro Gonzalez Jose Garcia Sole Daniel Jaque Garcia Department of Materials Science University of Milano-Bicocca Via R. Cozzi 55 20125 Milano Italy Dipartimento di Biotecnologie Universita di Verona and INSTM UdR Verona Strada le Grazie 15 37134 Verona Italy Institut National de la recherche Scientifique-Energie Materiaux et Telecommunications Universitd du Quebec Varennes QC PQ J3X 1S2 Canada Grupo de Fotonica e Fluidos Complexos Instituto de Fisica Universidade Federal de Alagoas 57072-970 Maceio Alagoas Brazil Departamento de Biologia Facultad de Ciencias Campus de Cantoblanco Universidad Autdnoma de Madrid Madrid 28049 Spain Fluorescence Imaging Group Departamento de Fisica de Maferiales Facultad de Ciencias Campus de Cantoblanco Universidad Aut6noma de Madrid Madrid 28049 Spain

Novel approaches for high contrast, deep tissue, in vivo fluorescence biomedical imaging are based on infrared-emitting nanoparticles working in the so-called second biological window （1,000-1,400 nm）. This allows for the acquisition of high resolution, deep tissue images due to the partial transparency of tissues in this particular spectral range. In addition, the optical excitation with low energy （infrared） photons also leads to a drastic reduction in the contribution of autofluorescence to the in vivo image. Nevertheless, as is demonstrated here, working solely in this biological window does not ensure a complete removal of autofluorescence as the specimens diet shows a remarkable infrared fluorescence that extends up to 1,100 nm. In this work, we show how the 1,340 nm emission band of Nd3. ions embedded in SrF2 nanoparticles can be used to produce autofluorescence free, high contrast in vivo fluorescence images. It is also dem- onstrated that the complete removal of the food-related infrared autofluorescence is imperative for the development of reliable biodistribution studies.

关键词： fluorescence imaging rare earth dopednanoparticles nanomedicine

Towards neurotoxicity testing in the 22nd century:a vision,a taste or a smell?

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Towards neurotoxicity testing in the 22nd century:a vision,a...

Extracellular vesicles from oviductal and uterine fluids supplementation in sequential in vitro culture improves bovine embryo quality

Neurotoxicity and Neurodegeneration:Local Effect and Global Impact--13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health

作者： Jordi Llorens Carla Soler-Martín blanca Cutillas Lara Sedó Sandra Saldaa-Ruiz Departament de Ciencies Fisiologiques Ⅱ Universitat de Barcelona - IDIBELLHospitalet de LlobregatSpain

The report "Toxicity testing in the 21 century:A vision and a strategy"（NRC,US NAS）,advocates for a toxicity testing strategy that relies on high throughput in vitro tests sensitive to key effects on "toxicity pathw... 详细信息

关键词： Towards neurotoxicity testing in the 22 century:a vision,a taste or a smell

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Journal of Animal Science and Biotechnology 2023年第1期14卷 114-133页

作者： Cláudia Lima Verde Leal Karina Canón-Beltrán Yulia N.Cajas Meriem Hamdi Aracelli Yaryes María Gemma Millán de la blanca Paula Beltrán-Brena Rosane Mazzarella Juliano Coelho da Silveira Alfonso Gutiérrez-Adán Encina M González Dimitrios Rizos Department of Animal reproduction National Center Institute for Agriculture and Food Research and Technology(CSIC-INIA)28040 MadridSpain. Departamento de Medicina Veterinaria Faculdade de Zootecnia e Engenharia de AlimentosUniversidade de Sao Paulo(FZEA-USP)PirassunungaBrazil. Facultad de Ciencias Agrarias y Ambientales Programa de Medicina VeterinariaFundacion Universitaria Juan de CastellanosTunjaColombia. Laboratorio de Biotecnologia de la reproduccion Animal Facultad de Ciencias AgropecuariasUniversidad de Cuenca(UC)EC010205 CuencaEcuador. Department of Anatomy and Embryology Veterinary Faculty-Universidad Complutense de Madrid(UCM)MadridSpain.

Background:In vitro production of bovine embryos is a well-established technology,but the in vitro culture(IVC)system still warrants improvements,especially regarding embryo *** study aimed to evaluate the effect of extracellular vesicles(EVs)isolated from oviductal(OF)and uterine fluid(UF)in sequential IVC on the development and quality of bovine *** were cultured in SOF supplemented with either BSA or EVs-depleted fetal calf serum(dFCS)in the presence(BSA-EV and dFCS-EV)or absence of EVs from OF(D1 to D4)and UF(D5 to D8),mimicking in vivo *** from oviducts(early luteal phase)and uterine horns(mid-luteal phase)from slaughtered heifers were isolated by size exclusion *** rate was recorded on days 7-8 and their quality was assessed based on lipid contents,mitochondrial activity and total cell numbers,as well as survival rate after *** mRNA abundance for lipid metabolism-related transcripts and levels of phosphorylated hormonesensitive lipase(pHSL)proteins were also ***,the expression levels of 383 miRNA in OF-and UF-EVs were assessed by ***:Blastocyst yield was lower(Preatments compared with dFCS *** rates after vitrification/warming were improved in dFCS-EVs(Preased(Pred with respective controls(dFCS and BSA),while lipid content was decreased in dFCSEV(P0.05).Lipid metabolism transcripts were affected by EVs and showed interaction with type of protein source in medium(PPARGC1B,LDLR,CD36,FASN and PNPLA2,Pre lower in dFCS(Pre differentially expressed between OF-and UF-EVs and only bta-miR-148b was increased in OF-EVs(P<0.05).Conclusions:Mimicking physiological conditions using EVs from OF and UF in sequential IVC does not affect embryo development but improves blast

关键词： Cattle Cryopreservation Embryo development Exosomes Lipid metabolism miRNAs Oviduct Uterus

Qigong improves balance in young women: a pilot study

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Journal of Integrative Medicine 2013年第4期11卷 241-245页

作者： María Victoria González López-Arza Enrique Varela-Donoso Jesús Montanero-Fernández Juan Rodríguez-Mansilla blanca González-Sánchez Luis González López-Arza Medicine and Surgery Department Extremadura University School of Medicine Adolor research Group of the Extremadura University Physical and rehabilitation Medicine Department Complutense University School of Medicine Mathematics Department Extremadura University School of Sciences Health Care Centre of Zafra

BACKGROUND： Balance problems are common in people of all ages and can lead to falls, thus causing fractures with consequent disability. Qigong practice has long been part of daily life in Chinese culture, and has good effects on physical health maintenance. OBJECTIVE： The present work describes the change in balance in young, healthy women after practising Qigong for eight weeks. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： The study took the form of a controlled, randomised longitudinal trial, and involved 30 women aged 18-25 years. The subjects had no prior experience of Qigong or Tai Chi and were unaware of the aims of the study. Subjects were randomly assigned to a Qigong intervention group or a control group. Those in the Qigong intervention group performed ＂exercises in 20 figures for health and long-life＂（Wang Ziping） for 1 h twice per week, for 4 weeks. The control group undertook no exercise at all. MAIN OUTCOME MEASUreS： The main outcome measure was the stabilometry values. These were obtained in a unipodal support test, using a plantar pressure platform with optical sensors. reSULTS： The Qigong subjects showed a significant improvement in their stabilometry results （40.1% pre-intervention and 56.4% post-intervention）（P〈0.045）, while no improvement was seen in the control group （51.2% pre-intervention and 53.5% post-intervention）. At the beginning of the intervention, the stabilometry values recorded for the Qigong intervention group were worse than those recorded for the control group （40.15% and 51.21% respectively; P=0.121）. However, a comparison of the post-intervention values between these groups showed that these differences have disappeared （P=0.653）. CONCLUSION： Qigong can improve balance in healthy, young women.

关键词： Qigong musculoskeletal equilibrium women pilot projects